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    Glycosylation

    Glycosylation is the event in which a carbohydrate is bonded to a hydroxyl or other reactive functional group. This is most commonly studied in terms of glycosylated proteins. Glycosylation of proteins is one of the most common post-translational modifications in cells. The most common of these are called N or O linked glycosylation.

    Webinars

    • APR 13, 2023 | 8:00 AM
      Novel subunit analysis for biotherapeutic development: increased coverage from a single injection
      Novel subunit analysis for biotherapeutic development: increased...
      Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
      Speaker: Haichuan Liu
      Sponsored By: SCIEX
      6
      NOV 30, 2022 | 11:00 AM
      How Cystatin C measurement contributes to health care equity
      How Cystatin C measurement contributes to health care equity
      Date: November 30 Time: 11:00am (PDT), 2:00pm (EDT), Kidney function is assessed in the laboratory by measuring serum creatinine (Cr) and/or......
      Speaker: Gabriella Lakos MD, PhD, D (ABMLI)
      Sponsored By: Binding Site
      12
      NOV 03, 2022 | 6:00 AM
      Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions
      Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral...
      Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
      Speaker: Mohamed Abdel-Mohsen
      Sponsored By: GenScript
      16
      DEC 09, 2021 | 6:00 AM
      Assessment of quality attributes of biotherapeutics leveraging a novel fragmentation technique
      Assessment of quality attributes of biotherapeutics leveraging...
      Date: December 9, 2021 Time: 6:00am (PDT), 9:00 am (EDT) As the number of biotherapeutic candidates in development is increasing, the requirements of analytical tools to understand the molec...
      Speaker: Armelle Martelet
      Sponsored By: SCIEX
      5
      OCT 27, 2021 | 6:00 AM
      Comprehensive characterization of Etanercept using the ZenoTOF 7600 system
      Comprehensive characterization of Etanercept using the ZenoTOF...
      Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
      Speaker: Xuezhi Bi, PhD
      Sponsored By: SCIEX
      5
      OCT 20, 2021 | 9:00 AM
      Comprehensive analysis of next generation biologics using advanced data interpretation software
      Comprehensive analysis of next generation biologics using advanced...
      Date: October 20, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Protein therapeutics is one of the major drug modalities in biopharma industry. With more and more elucidation of disease pathology,...
      Speaker: Zoe Zhang
      Sponsored By: SCIEX
      27
      OCT 12, 2021 | 9:00 AM
      An overview and demonstration of SCIEX Biologics Explorer software for biologics characterization
      An overview and demonstration of SCIEX Biologics Explorer software...
      Date: October 12, 2021 Time: 9:00am (PDT), 12:00pm (EDT) SCIEX’s next-generation Biologics Explorer software is an innovative platform for the comprehensive and deep characterization o...
      Speaker: Mona Hamada, Ph.D. , Stephen Sciuto, Ph.D.
      Sponsored By: SCIEX
      6
      AUG 24, 2021 | 11:00 AM
      EAD easy as 1-2-3: Making characterization of complex biotherapeutics routine
      EAD easy as 1-2-3: Making characterization of complex biotherapeutics...
      Date: August 24, 2021 Time: 11:00am (PDT), 1:00pm (EDT) Electron-based dissociation mechanisms have shown great promise for advanced characterization of biomolecules. However, routine adopti...
      Speaker: Matt Stone, PhD , Claire Bramwell, PhD
      Sponsored By: Sciex
      9 1
      SEP 22, 2020 | 10:30 AM
      Agilent LC-MS Released Glycan Workflow
      Agilent LC-MS Released Glycan Workflow
      The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This make...
      Speaker: Christopher Colangelo, PhD, MBA
      Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
      1
      SEP 22, 2020 | 10:00 AM
      Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software
      Characterization of N-linked glycans with the Released Glycans...
      Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
      Speaker: Rebecca Glaskin
      Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
      1
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      DEC 10, 2019 | 8:00 AM
      Expi293: New Tools for Structural Biology and Difficult to Express Proteins
      Expi293: New Tools for Structural Biology and Difficult to Express...
      DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
      Speaker: Jon Zmuda, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      NOV 06, 2019 | 6:00 AM
      Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
      Understanding the Pathogenesis of Human Influenza Virus: A Systems...
      Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
      Speaker: Rafael Medina Silva, PhD
      Presented at: Influenza Virtual Event Series 2019
      1
      NOV 01, 2018 | 12:00 AM
      Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
      Glycosylation and stabilization of programmed death ligand-1 suppresses...
      The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
      Speaker: Chia-Wei Li, PhD
      Presented at: Dimension of Time: From Culture to Assay
      1
      OCT 30, 2018 | 10:00 AM
      Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
      Post-translational Modifications and Data-Independent Acquisitions...
      DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
      Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
      Sponsored By: Cell Signaling Technology
      5
      OCT 10, 2017 | 7:00 AM
      WEBINAR: Achieving Higher Resolution Protein Impurity Analysis with Microfluidic CE
      WEBINAR: Achieving Higher Resolution Protein Impurity Analysis...
      DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
      Speaker: Anubhav Tripathi, PhD , James White, PhD
      Sponsored By: Revvity
      7
      SEP 07, 2017 | 9:00 AM
      WEBINAR: Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
      WEBINAR: Glycosylation and stabilization of programmed death ligand-1...
      DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
      Speaker: Chia-Wei Li, PhD
      Sponsored By: Essen BioScience
      5
      MAY 10, 2017 | 1:00 PM
      Modification of Glycans in Bioprocessing
      Modification of Glycans in Bioprocessing
      Glycosylation is an important product quality attribute for biotherapeutic proteins expressed in CHO cells. Glycoform variability can significantly affect the safety and efficacy of therapeut...
      Speaker: Ryan Boniface
      Presented at: 2017 Gibco ExpressionWorld
      4
      MAR 24, 2017 | 7:30 AM
      WEBINAR: Monoclonal Antibody Glycan Analysis 5 Times Faster Than HILIC
      WEBINAR: Monoclonal Antibody Glycan Analysis 5 Times Faster Than...
      DATE: March 24th, 2017TIME: 7:30AM PT, 10:30AM ET There is a growing demand in the biopharmaceutical industry for rapid N-glycosylation profiling of therapeutic antibodies....
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      12
      MAR 16, 2017 | 1:30 PM
      Humans and fish to study the cellular mechanisms of neuromuscular development
      Humans and fish to study the cellular mechanisms of neuromuscular...
      Studying the genetics of rare congenital disorders disrupting cognitive function has led to the identification of multiple disease genes that helped us better understand the mechanisms underl...
      Speaker: Chiara Manzini, PhD
      Presented at: Neuroscience Virtual Event Series 2017
      1
      FEB 01, 2017 | 8:00 AM
      WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques for the Analysis of a Development‐Phase Therapeutic Glycoprotein
      WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques...
      DATE: February 1, 2017TIME: 8:00AM PT, 11:00AM ETIn this presentation the complementarity of various liquid phase bioseparation methods including capillary electrophoresis and liquid ch...
      Speaker: Laura Salmeron
      Sponsored By: SCIEX
      13 3
      JUN 15, 2016 | 7:30 AM
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
      Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
      Speaker: Guinevere Kammeijer, MSc
      Sponsored By: Sciex, Sciex
      11 2
      MAR 10, 2016 | 8:00 AM
      Fully Automated, One Hour Sample Preparation for Ultrafast N-Glycosylation Analysis of Antibody Therapeutics
      Fully Automated, One Hour Sample Preparation for Ultrafast N-Glycosylation...
      DATE: March 10, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time SCIEX has recently introduced an easy-to-use magnetic bead based sample preparation workflow, enabling the prepa...
      Speaker: Andras Guttman, PhD
      Sponsored By: Sciex, Sciex
      9
    APR 13, 2023 | 8:00 AM
    Novel subunit analysis for biotherapeutic development: increased coverage from a single injection
    Novel subunit analysis for biotherapeutic development: increased...
    Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
    Speaker: Haichuan Liu
    Sponsored By: SCIEX
    6
    NOV 30, 2022 | 11:00 AM
    How Cystatin C measurement contributes to health care equity
    How Cystatin C measurement contributes to health care equity
    Date: November 30 Time: 11:00am (PDT), 2:00pm (EDT), Kidney function is assessed in the laboratory by measuring serum creatinine (Cr) and/or......
    Speaker: Gabriella Lakos MD, PhD, D (ABMLI)
    Sponsored By: Binding Site
    12
    NOV 03, 2022 | 6:00 AM
    Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions
    Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral...
    Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
    Speaker: Mohamed Abdel-Mohsen
    Sponsored By: GenScript
    16
    DEC 09, 2021 | 6:00 AM
    Assessment of quality attributes of biotherapeutics leveraging a novel fragmentation technique
    Assessment of quality attributes of biotherapeutics leveraging...
    Date: December 9, 2021 Time: 6:00am (PDT), 9:00 am (EDT) As the number of biotherapeutic candidates in development is increasing, the requirements of analytical tools to understand the molec...
    Speaker: Armelle Martelet
    Sponsored By: SCIEX
    5
    OCT 27, 2021 | 6:00 AM
    Comprehensive characterization of Etanercept using the ZenoTOF 7600 system
    Comprehensive characterization of Etanercept using the ZenoTOF...
    Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
    Speaker: Xuezhi Bi, PhD
    Sponsored By: SCIEX
    5
     
     
  • OCT 20, 2021 | 9:00 AM
    Comprehensive analysis of next generation biologics using advanced data interpretation software
    Comprehensive analysis of next generation biologics using advanced...
    Date: October 20, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Protein therapeutics is one of the major drug modalities in biopharma industry. With more and more elucidation of disease pathology,...
    Speaker: Zoe Zhang
    Sponsored By: SCIEX
    27
    OCT 12, 2021 | 9:00 AM
    An overview and demonstration of SCIEX Biologics Explorer software for biologics characterization
    An overview and demonstration of SCIEX Biologics Explorer software...
    Date: October 12, 2021 Time: 9:00am (PDT), 12:00pm (EDT) SCIEX’s next-generation Biologics Explorer software is an innovative platform for the comprehensive and deep characterization o...
    Speaker: Mona Hamada, Ph.D. , Stephen Sciuto, Ph.D.
    Sponsored By: SCIEX
    6
    AUG 24, 2021 | 11:00 AM
    EAD easy as 1-2-3: Making characterization of complex biotherapeutics routine
    EAD easy as 1-2-3: Making characterization of complex biotherapeutics...
    Date: August 24, 2021 Time: 11:00am (PDT), 1:00pm (EDT) Electron-based dissociation mechanisms have shown great promise for advanced characterization of biomolecules. However, routine adopti...
    Speaker: Matt Stone, PhD , Claire Bramwell, PhD
    Sponsored By: Sciex
    9 1
    SEP 22, 2020 | 10:30 AM
    Agilent LC-MS Released Glycan Workflow
    Agilent LC-MS Released Glycan Workflow
    The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This make...
    Speaker: Christopher Colangelo, PhD, MBA
    Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
    1
    SEP 22, 2020 | 10:00 AM
    Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software
    Characterization of N-linked glycans with the Released Glycans...
    Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
    Speaker: Rebecca Glaskin
    Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
    1
     
     
  • JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    DEC 10, 2019 | 8:00 AM
    Expi293: New Tools for Structural Biology and Difficult to Express Proteins
    Expi293: New Tools for Structural Biology and Difficult to Express...
    DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
    Speaker: Jon Zmuda, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    NOV 06, 2019 | 6:00 AM
    Understanding the Pathogenesis of Human Influenza Virus: A Systems Virology Approach
    Understanding the Pathogenesis of Human Influenza Virus: A Systems...
    Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
    Speaker: Rafael Medina Silva, PhD
    Presented at: Influenza Virtual Event Series 2019
    1
    NOV 01, 2018 | 12:00 AM
    Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
    Glycosylation and stabilization of programmed death ligand-1 suppresses...
    The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
    Speaker: Chia-Wei Li, PhD
    Presented at: Dimension of Time: From Culture to Assay
    1
     
     
  • OCT 30, 2018 | 10:00 AM
    Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
    Post-translational Modifications and Data-Independent Acquisitions...
    DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
    Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
    Sponsored By: Cell Signaling Technology
    5
    OCT 10, 2017 | 7:00 AM
    WEBINAR: Achieving Higher Resolution Protein Impurity Analysis with Microfluidic CE
    WEBINAR: Achieving Higher Resolution Protein Impurity Analysis...
    DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
    Speaker: Anubhav Tripathi, PhD , James White, PhD
    Sponsored By: Revvity
    7
    SEP 07, 2017 | 9:00 AM
    WEBINAR: Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
    WEBINAR: Glycosylation and stabilization of programmed death ligand-1...
    DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
    Speaker: Chia-Wei Li, PhD
    Sponsored By: Essen BioScience
    5
    MAY 10, 2017 | 1:00 PM
    Modification of Glycans in Bioprocessing
    Modification of Glycans in Bioprocessing
    Glycosylation is an important product quality attribute for biotherapeutic proteins expressed in CHO cells. Glycoform variability can significantly affect the safety and efficacy of therapeut...
    Speaker: Ryan Boniface
    Presented at: 2017 Gibco ExpressionWorld
    4
    MAR 24, 2017 | 7:30 AM
    WEBINAR: Monoclonal Antibody Glycan Analysis 5 Times Faster Than HILIC
    WEBINAR: Monoclonal Antibody Glycan Analysis 5 Times Faster Than...
    DATE: March 24th, 2017TIME: 7:30AM PT, 10:30AM ET There is a growing demand in the biopharmaceutical industry for rapid N-glycosylation profiling of therapeutic antibodies....
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    12
     
     
  • MAR 16, 2017 | 1:30 PM
    Humans and fish to study the cellular mechanisms of neuromuscular development
    Humans and fish to study the cellular mechanisms of neuromuscular...
    Studying the genetics of rare congenital disorders disrupting cognitive function has led to the identification of multiple disease genes that helped us better understand the mechanisms underl...
    Speaker: Chiara Manzini, PhD
    Presented at: Neuroscience Virtual Event Series 2017
    1
    FEB 01, 2017 | 8:00 AM
    WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques for the Analysis of a Development‐Phase Therapeutic Glycoprotein
    WEBINAR: N‐Linked Glycosylation Profiling: Rapid Separation Techniques...
    DATE: February 1, 2017TIME: 8:00AM PT, 11:00AM ETIn this presentation the complementarity of various liquid phase bioseparation methods including capillary electrophoresis and liquid ch...
    Speaker: Laura Salmeron
    Sponsored By: SCIEX
    13 3
    JUN 15, 2016 | 7:30 AM
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
    Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
    Speaker: Guinevere Kammeijer, MSc
    Sponsored By: Sciex, Sciex
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