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Glycosylation
Glycosylation is the event in which a carbohydrate is bonded to a hydroxyl or other reactive functional group. This is most commonly studied in terms of glycosylated proteins. Glycosylation of proteins is one of the most common post-translational modifications in cells. The most common of these are called N or O linked glycosylation.
APR 03, 2024 | 10:30 AM
C.E. CREDITS
We are leading the way in developing integrated online sampling and Process Analytical Technology (PAT) workflows for quick monitoring of critical quality attributes (CQA) to produce advance...
APR 03, 2024 | 9:00 AM
C.E. CREDITS
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
APR 13, 2023 | 8:00 AM
Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
APR 05, 2023 | 1:30 PM
Many commercially promising proteins are difficult-to-express (DTE) in living cells and are lost before an industrial production process can be established. Cell-free protein expression (CFP...
APR 05, 2023 | 1:15 PM
The biopharmaceutical industry is transitioning towards continuous biomanufacturing processes that require advanced analytical tools to monitor and control bioprocesses to produce high-quali...
NOV 30, 2022 | 11:00 AM
Date: November 30 Time: 11:00am (PDT), 2:00pm (EDT), Kidney function is assessed in the laboratory by measuring serum creatinine (Cr) and/or......
NOV 03, 2022 | 6:00 AM
Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
DEC 09, 2021 | 6:00 AM
Date: December 9, 2021 Time: 6:00am (PDT), 9:00 am (EDT) As the number of biotherapeutic candidates in development is increasing, the requirements of analytical tools to understand the molec...
OCT 27, 2021 | 6:00 AM
Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
OCT 20, 2021 | 9:00 AM
Date: October 20, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Protein therapeutics is one of the major drug modalities in biopharma industry. With more and more elucidation of disease pathology,...
OCT 12, 2021 | 9:00 AM
Date: October 12, 2021 Time: 9:00am (PDT), 12:00pm (EDT) SCIEX’s next-generation Biologics Explorer software is an innovative platform for the comprehensive and deep characterization o...
AUG 24, 2021 | 11:00 AM
Date: August 24, 2021 Time: 11:00am (PDT), 1:00pm (EDT) Electron-based dissociation mechanisms have shown great promise for advanced characterization of biomolecules. However, routine adopti...
SEP 22, 2020 | 10:30 AM
The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This make...
SEP 22, 2020 | 10:00 AM
Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
JUN 30, 2020 | 9:00 AM
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
MAY 12, 2020 | 9:00 AM
NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
DEC 10, 2019 | 8:00 AM
DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
NOV 06, 2019 | 6:00 AM
Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
NOV 01, 2018 | 12:00 AM
The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
OCT 30, 2018 | 10:00 AM
DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
OCT 10, 2017 | 7:00 AM
DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
