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    High Throughput Screening

    High Throughput Screening: a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry[1][2]. Using robotics, data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to quickly conduct millions of chemical, genetic, or pharmacological tests. Through this process one can rapidly identify active compounds, antibodies, or genes that modulate a particular biomolecular pathway.

    Webinars

    • MAY 07, 2020 | 7:00 AM
      A complete workflow for analysis of cfDNA: from plasma to variants
      A complete workflow for analysis of cfDNA: from plasma to variants
      DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
      Speaker: Shilpa Parakh , Nicole Roseman
      Sponsored By: Beckman Coulter Life Sciences, IDT
      13 10
      APR 30, 2020 | 9:00 AM
      Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
      Tools and methods for CRISPR-Cas9 screening for functional genomics...
      DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
      Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
      Sponsored By: Thermo Fisher Scientific
      23 1
      APR 29, 2020 | 6:00 AM
      High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
      High-Throughput assessment of ChIP-grade capability with Luminex...
      Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
      Speaker: Michael-Christopher Keogh, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 29, 2020 | 6:00 AM
      Experimental Design and Analytics for Customized High Throughput Ligand Screening in Developing Affinity Purification Solutions
      Experimental Design and Analytics for Customized High Throughput...
      ...
      Speaker: Sidharth Mohan
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 07, 2020 | 8:00 AM
      Best Practice Criteria for Pluripotent Stem Cell Lines
      Best Practice Criteria for Pluripotent Stem Cell Lines
      DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
      Speaker: Lyn Healy
      Sponsored By: STEMCELL Technologies
      22
      MAR 31, 2020 | 7:00 AM
      Investigation of NK cell-driven tumor immunity using novel image cytometry detection method
      Investigation of NK cell-driven tumor immunity using novel image...
      DATE: March 31, 2020 TIME: 7:00am PT, 10:00am PT Please join us for this webinar, during which we will present and discuss the promotion of NK cell-driven tumor immunity. In addition, we wil...
      Speaker: Lucas Ferrari de Andrade, Ph.D. , Leo Chan, Ph.D.
      Sponsored By: Nexcelom Bioscience
      10
      MAR 25, 2020 | 6:00 AM
      Metabolomics: An Evolving Approach to Cannabis Breeding
      Metabolomics: An Evolving Approach to Cannabis Breeding
      Household produce varieties such as ‘Red Delicious,’ ‘Campari,’ and ‘Earlidew’ have been selectively bred and have been enhanced for flavor since the 1990...
      Speaker: Caleb King
      Presented at: Cannabis Sciences Virtual Event Series 2020
      2
      MAR 24, 2020 | 10:00 AM
      Save your time on data analysis with new Batch Analysis feature in Axon pCLAMP 11 Software
      Save your time on data analysis with new Batch Analysis feature...
      DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
      Speaker: Jeffrey Tang, Ph.D.
      Sponsored By: Molecular Devices
      10
      MAR 05, 2020 | 9:00 AM
      An Update on H. pylori testing with a focus on the Houston Consensus recommendations
      An Update on H. pylori testing with a focus on the Houston Consensus...
      Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
      Speaker: David Graham, MD
      8
      FEB 19, 2020 | 11:00 AM
      Emerging as the New Gold Standard in Quality & Safety: Parallel DNA Based Cannabis Testing of Multiple Microbes
      Emerging as the New Gold Standard in Quality & Safety: Parallel...
      DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
      Speaker: Michael Hogan, Ph.D. , Benjamin Katchman, Ph.D.
      Sponsored By: PathogenDx
      7
      JAN 14, 2020 | 9:00 AM
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
      Speaker: Roy Sherwood, BSc, MSC, DPhil
      Sponsored By: Diasorin S.p.A.
      5
      JAN 14, 2020 | 8:00 AM
      CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
      CiPA initiative and validation of high-throughput methods to characterize...
      DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
      Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
      Sponsored By: Molecular Devices, Eurofins Discovery
      3
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Human Tissue models for better therapies
      Human Tissue models for better therapies
      The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
      Speaker: Sebastiaan Trietsch, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      DEC 05, 2019 | 9:00 AM
      Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
      Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
      DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
      Speaker: Mathias Holpert, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
      Sponsored By: Leica Biosystems, NanoString Technologies
      8
      NOV 06, 2019 | 7:30 AM
      Toward a universal influenza virus vaccine
      Toward a universal influenza virus vaccine
      Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
      Speaker: Adolfo Garcia-Sastre, PhD
      Presented at: Influenza Virtual Event Series 2019
      4
      OCT 24, 2019 | 10:30 AM
      Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
      Supercritical fluid chromatography of polar biomolecules at the...
      Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
      Speaker: Raffeal Bennett, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      OCT 24, 2019 | 6:00 AM
      Multidimension Chromatography; a Disruptive Technology - A Netflix Effect in the World of Chromatography!
      Multidimension Chromatography; a Disruptive Technology - A Netflix...
      Chromatography is the first choice in separation technique for a wide selection of applications, across many fields, ranging from simple to highly complex extracts. The main rationale for it...
      Speaker: Claude Mallet, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 24, 2019 | 8:00 AM
      Interrogating 3D spheroid versus 2D monolayer cell models in drug discovery using cell health microplate assays
      Interrogating 3D spheroid versus 2D monolayer cell models in drug...
      DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
      Speaker: Dr. Adyary Fallarero, Ph.D. Adjunct Professor/Docent in Pharmaceutical Biology , Dr. Leticia Montoya, Ph.D., Chemistry and Biochemistry
      Sponsored By: Thermo Fisher Scientific
      9
      SEP 17, 2019 | 6:00 AM
      Post-translational modification enrichment and quantitation for precision medicine and drug development
      Post-translational modification enrichment and quantitation for...
      DATE: September 17, 2019TIME: 6:00 am PDT, 9:00am EDT, 2:00pm BST, 3:00pm CEST Abstract: Learning Objectives: one two Webina...
      Speaker: Connie Jimenez, PhD , Manuel Tzouros, PhD
      Sponsored By: Cell Signaling Technology
      8 2
      SEP 11, 2019 | 9:00 AM
      Microbial Detection Total Solution Based on MGISEQ High-Throughput Sequencing Platform - Accelerating the Application of Metagenomics in the Screening and Prevention of Infectious Disease
      Microbial Detection Total Solution Based on MGISEQ High-Throughput...
      Traditional pathogen detection methods rely on the identification of pathogens known to be associated with a particular syndrome. In many cases, it involves complex methodology, lengthy proce...
      Speaker: Kin Kuok, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      2
      SEP 05, 2019 | 7:00 AM
      The bread and butter method of genomics: How to improve your (q)PCR
      The bread and butter method of genomics: How to improve your (q)PCR
      DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
      Speaker: Tim Schommartz, PhD
      Sponsored By: Eppendorf
      17 1
      AUG 22, 2019 | 6:00 AM
      In Vitro Screening Approaches to Estimate Human Hepatic Responses to Xenobiotic Exposures
      In Vitro Screening Approaches to Estimate Human Hepatic Responses...
      Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
      Speaker: Stephen Ferguson, PhD
      Presented at: Forensics & Toxicology 2019
      1
    MAY 07, 2020 | 7:00 AM
    A complete workflow for analysis of cfDNA: from plasma to variants
    A complete workflow for analysis of cfDNA: from plasma to variants
    DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
    Speaker: Shilpa Parakh , Nicole Roseman
    Sponsored By: Beckman Coulter Life Sciences, IDT
    13 10
    APR 30, 2020 | 9:00 AM
    Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
    Tools and methods for CRISPR-Cas9 screening for functional genomics...
    DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
    Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
    Sponsored By: Thermo Fisher Scientific
    23 1
    APR 29, 2020 | 6:00 AM
    High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
    High-Throughput assessment of ChIP-grade capability with Luminex...
    Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
    Speaker: Michael-Christopher Keogh, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 29, 2020 | 6:00 AM
    Experimental Design and Analytics for Customized High Throughput Ligand Screening in Developing Affinity Purification Solutions
    Experimental Design and Analytics for Customized High Throughput...
    ...
    Speaker: Sidharth Mohan
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 07, 2020 | 8:00 AM
    Best Practice Criteria for Pluripotent Stem Cell Lines
    Best Practice Criteria for Pluripotent Stem Cell Lines
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    Speaker: Lyn Healy
    Sponsored By: STEMCELL Technologies
    22
     
     
  • MAR 31, 2020 | 7:00 AM
    Investigation of NK cell-driven tumor immunity using novel image cytometry detection method
    Investigation of NK cell-driven tumor immunity using novel image...
    DATE: March 31, 2020 TIME: 7:00am PT, 10:00am PT Please join us for this webinar, during which we will present and discuss the promotion of NK cell-driven tumor immunity. In addition, we wil...
    Speaker: Lucas Ferrari de Andrade, Ph.D. , Leo Chan, Ph.D.
    Sponsored By: Nexcelom Bioscience
    10
    MAR 25, 2020 | 6:00 AM
    Metabolomics: An Evolving Approach to Cannabis Breeding
    Metabolomics: An Evolving Approach to Cannabis Breeding
    Household produce varieties such as ‘Red Delicious,’ ‘Campari,’ and ‘Earlidew’ have been selectively bred and have been enhanced for flavor since the 1990...
    Speaker: Caleb King
    Presented at: Cannabis Sciences Virtual Event Series 2020
    2
    MAR 24, 2020 | 10:00 AM
    Save your time on data analysis with new Batch Analysis feature in Axon pCLAMP 11 Software
    Save your time on data analysis with new Batch Analysis feature...
    DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
    Speaker: Jeffrey Tang, Ph.D.
    Sponsored By: Molecular Devices
    10
    MAR 05, 2020 | 9:00 AM
    An Update on H. pylori testing with a focus on the Houston Consensus recommendations
    An Update on H. pylori testing with a focus on the Houston Consensus...
    Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
    Speaker: David Graham, MD
    8
    FEB 19, 2020 | 11:00 AM
    Emerging as the New Gold Standard in Quality & Safety: Parallel DNA Based Cannabis Testing of Multiple Microbes
    Emerging as the New Gold Standard in Quality & Safety: Parallel...
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    Speaker: Michael Hogan, Ph.D. , Benjamin Katchman, Ph.D.
    Sponsored By: PathogenDx
    7
     
     
  • JAN 14, 2020 | 9:00 AM
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
    Speaker: Roy Sherwood, BSc, MSC, DPhil
    Sponsored By: Diasorin S.p.A.
    5
    JAN 14, 2020 | 8:00 AM
    CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
    CiPA initiative and validation of high-throughput methods to characterize...
    DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
    Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
    Sponsored By: Molecular Devices, Eurofins Discovery
    3
    JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Human Tissue models for better therapies
    Human Tissue models for better therapies
    The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
    Speaker: Sebastiaan Trietsch, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    DEC 05, 2019 | 9:00 AM
    Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
    Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
    DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
    Speaker: Mathias Holpert, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
    Sponsored By: Leica Biosystems, NanoString Technologies
    8
     
     
  • NOV 06, 2019 | 7:30 AM
    Toward a universal influenza virus vaccine
    Toward a universal influenza virus vaccine
    Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
    Speaker: Adolfo Garcia-Sastre, PhD
    Presented at: Influenza Virtual Event Series 2019
    4
    OCT 24, 2019 | 10:30 AM
    Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
    Supercritical fluid chromatography of polar biomolecules at the...
    Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
    Speaker: Raffeal Bennett, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
    OCT 24, 2019 | 6:00 AM
    Multidimension Chromatography; a Disruptive Technology - A Netflix Effect in the World of Chromatography!
    Multidimension Chromatography; a Disruptive Technology - A Netflix...
    Chromatography is the first choice in separation technique for a wide selection of applications, across many fields, ranging from simple to highly complex extracts. The main rationale for it...
    Speaker: Claude Mallet, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 24, 2019 | 8:00 AM
    Interrogating 3D spheroid versus 2D monolayer cell models in drug discovery using cell health microplate assays
    Interrogating 3D spheroid versus 2D monolayer cell models in drug...
    DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
    Speaker: Dr. Adyary Fallarero, Ph.D. Adjunct Professor/Docent in Pharmaceutical Biology , Dr. Leticia Montoya, Ph.D., Chemistry and Biochemistry
    Sponsored By: Thermo Fisher Scientific
    9
     
     
  • SEP 17, 2019 | 6:00 AM
    Post-translational modification enrichment and quantitation for precision medicine and drug development
    Post-translational modification enrichment and quantitation for...
    DATE: September 17, 2019TIME: 6:00 am PDT, 9:00am EDT, 2:00pm BST, 3:00pm CEST Abstract: Learning Objectives: one two Webina...
    Speaker: Connie Jimenez, PhD , Manuel Tzouros, PhD
    Sponsored By: Cell Signaling Technology
    8 2
    SEP 11, 2019 | 9:00 AM
    Microbial Detection Total Solution Based on MGISEQ High-Throughput Sequencing Platform - Accelerating the Application of Metagenomics in the Screening and Prevention of Infectious Disease
    Microbial Detection Total Solution Based on MGISEQ High-Throughput...
    Traditional pathogen detection methods rely on the identification of pathogens known to be associated with a particular syndrome. In many cases, it involves complex methodology, lengthy proce...
    Speaker: Kin Kuok, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    2
    SEP 05, 2019 | 7:00 AM
    The bread and butter method of genomics: How to improve your (q)PCR
    The bread and butter method of genomics: How to improve your (q)PCR
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    Speaker: Tim Schommartz, PhD
    Sponsored By: Eppendorf
    17 1
    AUG 22, 2019 | 6:00 AM
    In Vitro Screening Approaches to Estimate Human Hepatic Responses to Xenobiotic Exposures
    In Vitro Screening Approaches to Estimate Human Hepatic Responses...
    Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
    Speaker: Stephen Ferguson, PhD
    Presented at: Forensics & Toxicology 2019
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