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    High Throughput

    High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.

    Webinars

    • FEB 13, 2019 | 10:30 AM
      Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
      Accurate Clinical Concentration-Response Predictions for Cardiac...
      Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
      Speaker: Weihsueh Chiu, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 1
      JAN 31, 2019 | 1:30 PM
      Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
      Standardization of Cell Viability Assays in Primary Cells as a...
      Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
      Speaker: Simon Kaja, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      2
      JAN 31, 2019 | 12:00 PM
      From Start to Finish, Bio-Techne Solutions for Bioprocessing
      From Start to Finish, Bio-Techne Solutions for Bioprocessing
      As the pace of biotherapeutic approvals increases, so does the pressure on makers of new biologics to complete their development processes faster and more efficiently. The success of the drug...
      Speaker: Christopher Heger, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      Sponsored By: ACD - A Bio-Techne Brand
      3 1
      JAN 31, 2019 | 10:30 AM
      Overcoming Limitations of Conventional Tag Systems - Strep-Tactin® XT Applications
      Overcoming Limitations of Conventional Tag Systems - Strep-Tactin®...
      The Strep-Tactin®XT:Twin-Strep-tag®-purification system enables protein purification at high yields and purity under physiological conditions. Providing the highest binding affinity a...
      Speaker: Dennis Karthaus, MS
      Presented at: BioProcessing Virtual Event Series 2019
      2
      JAN 31, 2019 | 10:30 AM
      Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries to Improve Process Efficiencies
      Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries...
      Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
      Speaker: Buzz Lobbezoo
      Presented at: BioProcessing Virtual Event Series 2019
      Sponsored By: Astrea Bioseparations
      1
      JAN 31, 2019 | 9:00 AM
      Streamlining the Biologics Development Process: From Transient to Stable Production in the ExpiCHO System
      Streamlining the Biologics Development Process: From Transient...
      The biologics development process is fraught with risks from pre-clinical studies through clinical evaluation. Prominent among these risks are changes in the critical quality attributes of th...
      Speaker: Jon Zmuda, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      JAN 31, 2019 | 7:30 AM
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      JAN 31, 2019 | 6:00 AM
      Overcoming Challenges in EuCODE Cell Culture Platform Development
      Overcoming Challenges in EuCODE Cell Culture Platform Development
      Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
      Speaker: Weimin Lin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      3
      DEC 11, 2018 | 10:00 AM
      Combining Reichert's SPR Systems With Other Informative Techniques
      Combining Reichert's SPR Systems With Other Informative Techniques
      DATE: December 11, 2018TIME: 11:00 PSTThis webinar will focus on how Reichert's Surface Plasmon Resonance (SPR) systems can generate additional valuable information that is not...
      Speaker: Phillip Page, PhD , Mary Murphy, PhD
      Sponsored By: Ametek
      3
      DEC 06, 2018 | 7:00 AM
      Image-based screening for precision medicine and immunotherapy
      Image-based screening for precision medicine and immunotherapy
      DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
      Speaker: Dr. Gregory Vladimer
      Sponsored By: Revvity
      6
      DEC 06, 2018 | 8:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      2
      DEC 06, 2018 | 1:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      8
      NOV 29, 2018 | 7:00 AM
      Quatro Décadas de Hepatite C. Testar, Tratar, Curar
      Quatro Décadas de Hepatite C. Testar, Tratar, Curar
      DATE:    November 29, 2018TIME:    15:00pm WET, 07:00am PST O vírus da Hepatite C (HCV) é uma infeção mundial, que...
      Speaker: Rui Tato Marinho, MD, PhD
      Sponsored By: Abbott
      6
      NOV 15, 2018 | 11:00 AM
      LIVE TRAINING: Differentiating neurons
      LIVE TRAINING: Differentiating neurons
      Generation of robust iPSC-derived neural stem cell cultures and neurons with shorter maturation times provide opportunities for quick and reliable generation of neuronal in vitro models. This...
      Speaker: Jordan Dizon
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      7
      NOV 07, 2018 | 8:00 PM
      Analysis of Surface Antigens on Exosomes
      Analysis of Surface Antigens on Exosomes
      DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
      Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      3 1
      NOV 07, 2018 | 7:00 AM
      Analysis of Surface Antigens on Exosomes
      Analysis of Surface Antigens on Exosomes
      DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...
      Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      11 1
      NOV 01, 2018 | 12:00 AM
      Real-time analysis of cellular phagocytosis
      Real-time analysis of cellular phagocytosis
      Alongside intense efforts to exploit T-cells as immunotherapies for cancer (e.g. checkpoint inhibitors, CAR-T, T-cell metabolism), researchers are increasingly considering other immune cell t...
      Speaker: Tim Dale
      Presented at: Dimension of Time: From Culture to Assay
      1
      NOV 01, 2018 | 12:00 AM
      Advanced 3D cell models for cancer biology using real time live-cell analysis
      Advanced 3D cell models for cancer biology using real time live-cell...
      Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
      Speaker: Kalpana Patel
      Presented at: Dimension of Time: From Culture to Assay
      2
      OCT 30, 2018 | 10:00 AM
      Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
      Post-translational Modifications and Data-Independent Acquisitions...
      DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
      Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
      Sponsored By: Cell Signaling Technology
      5
      OCT 25, 2018 | 12:00 PM
      Through the Looking Glass, and What Amino Acids Found There
      Through the Looking Glass, and What Amino Acids Found There
      Analytical chemistry can take you to strange places - for me it has been to the bottom of a quarry, being covered in dirt, excavating sesame-seed sized fossils that allow us to work out when...
      Speaker: Kirsty Penkman, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      OCT 25, 2018 | 10:30 AM
      Trash or Treasure: Optimizing Titration Electrodes and Consumables
      Trash or Treasure: Optimizing Titration Electrodes and Consumables
      Everyone that uses titration in their lab knows how simple and fast the technique can be.  However, uncertainty around when to replace electrodes creates confusion. Reagent quality, tubi...
      Speaker: Jessica McVay , Lori Spafford
      Presented at: Analytical Chemistry Virtual Event Series 2018
      Sponsored By: Metrohm USA
      1
      OCT 24, 2018 | 1:30 PM
      Accessories and Techniques for FT-IR Sample Analysis
      Accessories and Techniques for FT-IR Sample Analysis
      This intensive workshop will introduce infrared spectroscopy, outline the various sample handling methods and provide guidance on the numerous transmission and reflectance methods available f...
      Speaker: Richard Larsen, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      OCT 24, 2018 | 12:00 PM
      Ion Mobility-Mass Spectrometry in the -Omics
      Ion Mobility-Mass Spectrometry in the -Omics
      Ion mobility-mass spectrometry (IM-MS) is a rapid, gas-phase separation technique that has become an integral part of the analytical repertoire of techniques for the -omics. This method coupl...
      Speaker: Christopher Chouinard, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      OCT 24, 2018 | 9:00 AM
      Keynote Presentation: Solid Phase Microextraction: New Developments in Bioanalysis and Medical Applications
      Keynote Presentation: Solid Phase Microextraction: New Developments...
      Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
      Speaker: Barbara Bojko, PhD , Janusz Pawliszyn, PhD, FCIC, FRSC
      Presented at: Analytical Chemistry Virtual Event Series 2018
      2
    FEB 13, 2019 | 10:30 AM
    Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
    Accurate Clinical Concentration-Response Predictions for Cardiac...
    Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
    Speaker: Weihsueh Chiu, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 1
    JAN 31, 2019 | 1:30 PM
    Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
    Standardization of Cell Viability Assays in Primary Cells as a...
    Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
    Speaker: Simon Kaja, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    2
    JAN 31, 2019 | 12:00 PM
    From Start to Finish, Bio-Techne Solutions for Bioprocessing
    From Start to Finish, Bio-Techne Solutions for Bioprocessing
    As the pace of biotherapeutic approvals increases, so does the pressure on makers of new biologics to complete their development processes faster and more efficiently. The success of the drug...
    Speaker: Christopher Heger, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    Sponsored By: ACD - A Bio-Techne Brand
    3 1
    JAN 31, 2019 | 10:30 AM
    Overcoming Limitations of Conventional Tag Systems - Strep-Tactin® XT Applications
    Overcoming Limitations of Conventional Tag Systems - Strep-Tactin®...
    The Strep-Tactin®XT:Twin-Strep-tag®-purification system enables protein purification at high yields and purity under physiological conditions. Providing the highest binding affinity a...
    Speaker: Dennis Karthaus, MS
    Presented at: BioProcessing Virtual Event Series 2019
    2
    JAN 31, 2019 | 10:30 AM
    Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries to Improve Process Efficiencies
    Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries...
    Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
    Speaker: Buzz Lobbezoo
    Presented at: BioProcessing Virtual Event Series 2019
    Sponsored By: Astrea Bioseparations
    1
     
     
  • JAN 31, 2019 | 9:00 AM
    Streamlining the Biologics Development Process: From Transient to Stable Production in the ExpiCHO System
    Streamlining the Biologics Development Process: From Transient...
    The biologics development process is fraught with risks from pre-clinical studies through clinical evaluation. Prominent among these risks are changes in the critical quality attributes of th...
    Speaker: Jon Zmuda, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    JAN 31, 2019 | 7:30 AM
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    JAN 31, 2019 | 6:00 AM
    Overcoming Challenges in EuCODE Cell Culture Platform Development
    Overcoming Challenges in EuCODE Cell Culture Platform Development
    Ambrx’s mammalian expression platform (EuCODE™) enables non-native amino acids (nnAAs) through an expanded genetic code to both generate novel bio-therapeutics and to optimize the...
    Speaker: Weimin Lin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    3
    DEC 11, 2018 | 10:00 AM
    Combining Reichert's SPR Systems With Other Informative Techniques
    Combining Reichert's SPR Systems With Other Informative Techniques
    DATE: December 11, 2018TIME: 11:00 PSTThis webinar will focus on how Reichert's Surface Plasmon Resonance (SPR) systems can generate additional valuable information that is not...
    Speaker: Phillip Page, PhD , Mary Murphy, PhD
    Sponsored By: Ametek
    3
    DEC 06, 2018 | 7:00 AM
    Image-based screening for precision medicine and immunotherapy
    Image-based screening for precision medicine and immunotherapy
    DATE: December 06, 2018TIME:  7:00AM PSTHigh-throughput confocal microscopy has changed the way drug screening can be performed, by enabling the detection of single-cell pheno...
    Speaker: Dr. Gregory Vladimer
    Sponsored By: Revvity
    6
     
     
  • DEC 06, 2018 | 8:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    2
    DEC 06, 2018 | 1:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    8
    NOV 29, 2018 | 7:00 AM
    Quatro Décadas de Hepatite C. Testar, Tratar, Curar
    Quatro Décadas de Hepatite C. Testar, Tratar, Curar
    DATE:    November 29, 2018TIME:    15:00pm WET, 07:00am PST O vírus da Hepatite C (HCV) é uma infeção mundial, que...
    Speaker: Rui Tato Marinho, MD, PhD
    Sponsored By: Abbott
    6
    NOV 15, 2018 | 11:00 AM
    LIVE TRAINING: Differentiating neurons
    LIVE TRAINING: Differentiating neurons
    Generation of robust iPSC-derived neural stem cell cultures and neurons with shorter maturation times provide opportunities for quick and reliable generation of neuronal in vitro models. This...
    Speaker: Jordan Dizon
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    7
    NOV 07, 2018 | 8:00 PM
    Analysis of Surface Antigens on Exosomes
    Analysis of Surface Antigens on Exosomes
    DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
    Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    3 1
     
     
  • NOV 07, 2018 | 7:00 AM
    Analysis of Surface Antigens on Exosomes
    Analysis of Surface Antigens on Exosomes
    DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...
    Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    11 1
    NOV 01, 2018 | 12:00 AM
    Real-time analysis of cellular phagocytosis
    Real-time analysis of cellular phagocytosis
    Alongside intense efforts to exploit T-cells as immunotherapies for cancer (e.g. checkpoint inhibitors, CAR-T, T-cell metabolism), researchers are increasingly considering other immune cell t...
    Speaker: Tim Dale
    Presented at: Dimension of Time: From Culture to Assay
    1
    NOV 01, 2018 | 12:00 AM
    Advanced 3D cell models for cancer biology using real time live-cell analysis
    Advanced 3D cell models for cancer biology using real time live-cell...
    Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
    Speaker: Kalpana Patel
    Presented at: Dimension of Time: From Culture to Assay
    2
    OCT 30, 2018 | 10:00 AM
    Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
    Post-translational Modifications and Data-Independent Acquisitions...
    DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
    Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
    Sponsored By: Cell Signaling Technology
    5
    OCT 25, 2018 | 12:00 PM
    Through the Looking Glass, and What Amino Acids Found There
    Through the Looking Glass, and What Amino Acids Found There
    Analytical chemistry can take you to strange places - for me it has been to the bottom of a quarry, being covered in dirt, excavating sesame-seed sized fossils that allow us to work out when...
    Speaker: Kirsty Penkman, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
     
     
  • OCT 25, 2018 | 10:30 AM
    Trash or Treasure: Optimizing Titration Electrodes and Consumables
    Trash or Treasure: Optimizing Titration Electrodes and Consumables
    Everyone that uses titration in their lab knows how simple and fast the technique can be.  However, uncertainty around when to replace electrodes creates confusion. Reagent quality, tubi...
    Speaker: Jessica McVay , Lori Spafford
    Presented at: Analytical Chemistry Virtual Event Series 2018
    Sponsored By: Metrohm USA
    1
    OCT 24, 2018 | 1:30 PM
    Accessories and Techniques for FT-IR Sample Analysis
    Accessories and Techniques for FT-IR Sample Analysis
    This intensive workshop will introduce infrared spectroscopy, outline the various sample handling methods and provide guidance on the numerous transmission and reflectance methods available f...
    Speaker: Richard Larsen, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
    OCT 24, 2018 | 12:00 PM
    Ion Mobility-Mass Spectrometry in the -Omics
    Ion Mobility-Mass Spectrometry in the -Omics
    Ion mobility-mass spectrometry (IM-MS) is a rapid, gas-phase separation technique that has become an integral part of the analytical repertoire of techniques for the -omics. This method coupl...
    Speaker: Christopher Chouinard, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
    OCT 24, 2018 | 9:00 AM
    Keynote Presentation: Solid Phase Microextraction: New Developments in Bioanalysis and Medical Applications
    Keynote Presentation: Solid Phase Microextraction: New Developments...
    Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
    Speaker: Barbara Bojko, PhD , Janusz Pawliszyn, PhD, FCIC, FRSC
    Presented at: Analytical Chemistry Virtual Event Series 2018
    2
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