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    Immunohistochemistry

    Immunohistochemistry: an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease. IHC is widely used for diagnosis of cancers; specific tumor antigens are expressed de novo or up-regulated in certain cancers. The IHC technique is routinely used as an important tool in health care and pathology for e.g. diagnostic purposes or to stratify patients for optimized treatment regimes. IHC is also widely used in research where molecules of interest are analyzed to study their roles in both healthy and diseased cells and tissues on the molecular, cellular or tissue level.

    Webinars

    • NOV 07, 2019 | 10:00 AM
      Akoya Biosciences Webinar Series: Validating Multiplexed Antibody Panels for Pancreatic Research Applications
      Akoya Biosciences Webinar Series: Validating Multiplexed Antibody...
      DATE: November 7, 2019TIME: 10:00am PST, 1:00pm EST Studying the pathogenesis of diabetes requires detailed analysis of the pancreatic islet microenvironment and its numerous c...
      Speaker: Diane Saunders, PhD , Grady Carlson, PhD
      Sponsored By: Akoya Biosciences
      5
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      OCT 10, 2019 | 10:30 AM
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
      Speaker: Troy McEachron, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      SEP 26, 2019 | 10:30 AM
      Discover the genes that matter while preserving spatial information: The Visium Gene Expression Solution
      Discover the genes that matter while preserving spatial information:...
      The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, the...
      Speaker: Nikhil Rao
      Presented at: Cell Biology Virtual Event Series 2019
      1
      AUG 27, 2019 | 9:00 AM
      Akoya Biosciences Webinar Series:  Comprehensive Meta-analysis of Biomarker Technologies for Predictive Response of PD-1/PD-L1 Checkpoint Therapies
      Akoya Biosciences Webinar Series: Comprehensive Meta-analysis...
      DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
      Speaker: Cliff Hoyt, PhD , Steve Lu
      Sponsored By: Akoya Biosciences
      5
      JUL 30, 2019 | 10:00 AM
      Validating antibodies for research applications in IHC
      Validating antibodies for research applications in IHC
      DATE: July 30, 2019TIME: 10:00am PT/ 1:00pm ET The importance of building a validation structure within your lab cannot be overstated. Once in place, the ability to identify high...
      Speaker: Will Howat, PhD , Damian Cockfield
      Sponsored By: Leica Biosystems
      12
      JUN 05, 2019 | 5:00 PM
      Everyday culture practice - Improving reproducibility in cell culture
      Everyday culture practice - Improving reproducibility in cell...
      DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
      Speaker: Jessica Wagener, PhD
      Sponsored By: Eppendorf
      23 2
      MAY 16, 2019 | 4:00 PM
      Towards Standardized Workflows - A focus on microbiome insights
      Towards Standardized Workflows - A focus on microbiome insights
      DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
      Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
      Sponsored By: Eppendorf
      10 2
      MAR 21, 2019 | 7:00 AM
      Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
      Phenotyping the tumor micro-environment with advanced tissue-based...
      DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
      Speaker: Katir Patel, PhD
      Sponsored By: Ultivue
      11
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      NOV 15, 2018 | 10:00 AM
      Multiplex fluorescence immunohistochemistry using the Ultivue InSituPlex platform on the Leica Biosystems BOND RX
      Multiplex fluorescence immunohistochemistry using the Ultivue...
      DATE:  November 15, 2018TIME:  10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
      Speaker: Traci DeGeer, BS, HT (ASCP) HTL, QIHC , Alexander Klimowicz
      Sponsored By: Leica Biosystems
      6 1
      OCT 17, 2018 | 9:00 AM
      A comparative study of turnaround times for common hematopathology panels on the Leica Biosystems BOND‑III and the Roche Tissue Diagnostics BenchMark ULTRA instruments.
      A comparative study of turnaround times for common hematopathology...
      DATE: October 17, 2018TIME: 09:00am PT, 11:00pm CT, 12:00pm, ET Each patient case request can vary in what is required to make a diagnosis by the pathologist.Many times, the patholog...
      Speaker: David Roche , Melissa Boyd
      Sponsored By: Leica Biosystems
      4
      OCT 03, 2018 | 9:00 AM
      Mechanisms of Myeloid Immunosuppression:  Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
      Mechanisms of Myeloid Immunosuppression: Functional Characterization...
      DATE:  October 3, 2018TIME:  9:00am PDT, 12:00pm EDT Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) a...
      Speaker: Christopher Grange
      Sponsored By: Cell Signaling Technology
      3
      MAY 02, 2018 | 8:00 AM
      Five steps for publication-quality immunohistochemistry imaging
      Five steps for publication-quality immunohistochemistry imaging
      Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
      Speaker: Jason Kilgore
      Sponsored By: Thermo Fisher Scientific
      10
      APR 12, 2018 | 10:30 AM
      The Genome in 3D: A Clinical Biomarker Platform
      The Genome in 3D: A Clinical Biomarker Platform
      In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
      Speaker: Kevin Little, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      FEB 22, 2018 | 7:30 AM
      Keynote Presentation: Predictive Biomarkers to Diagnostic Tests - Scientific and Regulatory Consideration in Development of Companion Diagnostic Tests
      Keynote Presentation: Predictive Biomarkers to Diagnostic Tests...
      The path form biomarker discovery to conversion to a clinically useful companion diagnostic test presents many challenges. The talk will outline the regulatory requirements to developing a su...
      Speaker: Janaki Veeraraghavan, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      DEC 06, 2017 | 9:00 AM
      Immunohistochemistry Protocol Optimization and Troubleshooting Tips
      Immunohistochemistry Protocol Optimization and Troubleshooting...
      DATE: December 13, 2017TIME: 9:00am PT, 12:00pm ET Listen in as our scientific expert, Tom Ruyle, discusses how to optimize your IHC  protocol and reviews top troublesho...
      Speaker: Thomas Ruyle
      Presented at: Abcam virtual exhibition: support and products to advance your research
      Sponsored By: Abcam
      8 1
      NOV 08, 2017 | 12:00 PM
      Combined immunohistochemistry and RNA in situ hybridization to elucidate tumor molecular heterogeneity in prostate cancer
      Combined immunohistochemistry and RNA in situ hybridization to...
      Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
      Speaker: Nallasivam Palanisamy, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      Sponsored By: Advanced Cell Diagnostics
      3
      JUL 01, 2017 | 8:00 AM
      Examining the negative impacts of bioflavonoids on the DNA damage response and DNA repair mechanisms in mouse embryonic stem cells
      Examining the negative impacts of bioflavonoids on the DNA damage...
      Bioflavonoids are dietary agents found in everyday food items such as fruits, vegetables, and legumes. It has been suggested that bioflavonoids be used with chemotherapeutics as an anti-cance...
      Speaker: Donna Goodenow
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUL 01, 2017 | 12:00 AM
      Comparison of the Teratoma assay and in vitro surrogate tests for assessment of pluripotency of human pluripotent stem cells
      Comparison of the Teratoma assay and in vitro surrogate tests...
      For optimal use of human induced pluripotent stem cells (hiPSCs) it is essential to identify lines that are fully reprogrammed and of high quality with proven pluripotency in terms of differe...
      Speaker: Christian Freund
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      MAY 30, 2017 | 9:00 AM
      Protein and Cell Analysis Education Series featuring the Antibody Validation Forum
      Protein and Cell Analysis Education Series featuring the Antibody...
      Addressing the antibody reproducibility crisis: A panel discussion with key scientific leaders  Reproducibility and antibody validation standards are two significant challenges f...
      Speaker: Aled Edwards, PhD , Matt Baker , Anita Bandrowski, PhD , Paul Wallace, PhD , John Rogers, PhD , Christoph Hergersberg, PhD
      Presented at: Protein and Cell Analysis Education Series
      15
      APR 25, 2017 | 10:00 AM
      WEBINAR: Discover Potentially Predictive Immuno-Oncology Biomarkers using Next-Gen Sequencing
      WEBINAR: Discover Potentially Predictive Immuno-Oncology Biomarkers...
      DATE: April 25, 2017TIME: 10:00am PT, 1:00pm ETImmunotherapy has emerged as one of the most promising options for the future treatment of a growing number of cancers and is to...
      Speaker: Fiona Hyland , Carl Morrison MD, DVM
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      6 1
      MAR 21, 2017 | 10:00 AM
      WEBINAR: Application of combined RNA in situ hybridization and multiplex immunohistochemistry to unravel tumor heterogeneity in prostate cancer
      WEBINAR: Application of combined RNA in situ hybridization and...
      DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By:      Prostate cancer is a complex disease with multiple tumors originating independent...
      Speaker: Nallasivam Palanisamy, PhD , Courtney Anderson, PhD
      Sponsored By: Novus Biologicals a Bio-Techne Brand
      20 9
      JAN 17, 2017 | 8:00 AM
      An Introduction to Immunohistochemistry Principles with Troubleshooting Tips
      An Introduction to Immunohistochemistry Principles with Troubleshooting...
      Discuss common IHC problems and review tips and techniques for your experiments with Dr Carolyn Miazga including, sample processing antigen retrieval signal amplification controls...
      Speaker: Carolyn Miazga, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      5
    NOV 07, 2019 | 10:00 AM
    Akoya Biosciences Webinar Series: Validating Multiplexed Antibody Panels for Pancreatic Research Applications
    Akoya Biosciences Webinar Series: Validating Multiplexed Antibody...
    DATE: November 7, 2019TIME: 10:00am PST, 1:00pm EST Studying the pathogenesis of diabetes requires detailed analysis of the pancreatic islet microenvironment and its numerous c...
    Speaker: Diane Saunders, PhD , Grady Carlson, PhD
    Sponsored By: Akoya Biosciences
    5
    OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
    OCT 10, 2019 | 10:30 AM
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
    Speaker: Troy McEachron, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    SEP 26, 2019 | 10:30 AM
    Discover the genes that matter while preserving spatial information: The Visium Gene Expression Solution
    Discover the genes that matter while preserving spatial information:...
    The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, the...
    Speaker: Nikhil Rao
    Presented at: Cell Biology Virtual Event Series 2019
    1
    AUG 27, 2019 | 9:00 AM
    Akoya Biosciences Webinar Series:  Comprehensive Meta-analysis of Biomarker Technologies for Predictive Response of PD-1/PD-L1 Checkpoint Therapies
    Akoya Biosciences Webinar Series: Comprehensive Meta-analysis...
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    Speaker: Cliff Hoyt, PhD , Steve Lu
    Sponsored By: Akoya Biosciences
    5
     
     
  • JUL 30, 2019 | 10:00 AM
    Validating antibodies for research applications in IHC
    Validating antibodies for research applications in IHC
    DATE: July 30, 2019TIME: 10:00am PT/ 1:00pm ET The importance of building a validation structure within your lab cannot be overstated. Once in place, the ability to identify high...
    Speaker: Will Howat, PhD , Damian Cockfield
    Sponsored By: Leica Biosystems
    12
    JUN 05, 2019 | 5:00 PM
    Everyday culture practice - Improving reproducibility in cell culture
    Everyday culture practice - Improving reproducibility in cell...
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    Speaker: Jessica Wagener, PhD
    Sponsored By: Eppendorf
    23 2
    MAY 16, 2019 | 4:00 PM
    Towards Standardized Workflows - A focus on microbiome insights
    Towards Standardized Workflows - A focus on microbiome insights
    DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
    Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
    Sponsored By: Eppendorf
    10 2
    MAR 21, 2019 | 7:00 AM
    Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
    Phenotyping the tumor micro-environment with advanced tissue-based...
    DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
    Speaker: Katir Patel, PhD
    Sponsored By: Ultivue
    11
    FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
     
     
  • NOV 15, 2018 | 10:00 AM
    Multiplex fluorescence immunohistochemistry using the Ultivue InSituPlex platform on the Leica Biosystems BOND RX
    Multiplex fluorescence immunohistochemistry using the Ultivue...
    DATE:  November 15, 2018TIME:  10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
    Speaker: Traci DeGeer, BS, HT (ASCP) HTL, QIHC , Alexander Klimowicz
    Sponsored By: Leica Biosystems
    6 1
    OCT 17, 2018 | 9:00 AM
    A comparative study of turnaround times for common hematopathology panels on the Leica Biosystems BOND‑III and the Roche Tissue Diagnostics BenchMark ULTRA instruments.
    A comparative study of turnaround times for common hematopathology...
    DATE: October 17, 2018TIME: 09:00am PT, 11:00pm CT, 12:00pm, ET Each patient case request can vary in what is required to make a diagnosis by the pathologist.Many times, the patholog...
    Speaker: David Roche , Melissa Boyd
    Sponsored By: Leica Biosystems
    4
    OCT 03, 2018 | 9:00 AM
    Mechanisms of Myeloid Immunosuppression:  Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
    Mechanisms of Myeloid Immunosuppression: Functional Characterization...
    DATE:  October 3, 2018TIME:  9:00am PDT, 12:00pm EDT Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) a...
    Speaker: Christopher Grange
    Sponsored By: Cell Signaling Technology
    3
    MAY 02, 2018 | 8:00 AM
    Five steps for publication-quality immunohistochemistry imaging
    Five steps for publication-quality immunohistochemistry imaging
    Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
    Speaker: Jason Kilgore
    Sponsored By: Thermo Fisher Scientific
    10
    APR 12, 2018 | 10:30 AM
    The Genome in 3D: A Clinical Biomarker Platform
    The Genome in 3D: A Clinical Biomarker Platform
    In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
    Speaker: Kevin Little, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
     
     
  • FEB 22, 2018 | 7:30 AM
    Keynote Presentation: Predictive Biomarkers to Diagnostic Tests - Scientific and Regulatory Consideration in Development of Companion Diagnostic Tests
    Keynote Presentation: Predictive Biomarkers to Diagnostic Tests...
    The path form biomarker discovery to conversion to a clinically useful companion diagnostic test presents many challenges. The talk will outline the regulatory requirements to developing a su...
    Speaker: Janaki Veeraraghavan, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    DEC 06, 2017 | 9:00 AM
    Immunohistochemistry Protocol Optimization and Troubleshooting Tips
    Immunohistochemistry Protocol Optimization and Troubleshooting...
    DATE: December 13, 2017TIME: 9:00am PT, 12:00pm ET Listen in as our scientific expert, Tom Ruyle, discusses how to optimize your IHC  protocol and reviews top troublesho...
    Speaker: Thomas Ruyle
    Presented at: Abcam virtual exhibition: support and products to advance your research
    Sponsored By: Abcam
    8 1
    NOV 08, 2017 | 12:00 PM
    Combined immunohistochemistry and RNA in situ hybridization to elucidate tumor molecular heterogeneity in prostate cancer
    Combined immunohistochemistry and RNA in situ hybridization to...
    Currently, prostate cancer is the second leading cause of death from cancer in North America, the most frequent malignancy in men from all ethnicities, surpassing lung cancer. Prostate tumors...
    Speaker: Nallasivam Palanisamy, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    Sponsored By: Advanced Cell Diagnostics
    3
    JUL 01, 2017 | 8:00 AM
    Examining the negative impacts of bioflavonoids on the DNA damage response and DNA repair mechanisms in mouse embryonic stem cells
    Examining the negative impacts of bioflavonoids on the DNA damage...
    Bioflavonoids are dietary agents found in everyday food items such as fruits, vegetables, and legumes. It has been suggested that bioflavonoids be used with chemotherapeutics as an anti-cance...
    Speaker: Donna Goodenow
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUL 01, 2017 | 12:00 AM
    Comparison of the Teratoma assay and in vitro surrogate tests for assessment of pluripotency of human pluripotent stem cells
    Comparison of the Teratoma assay and in vitro surrogate tests...
    For optimal use of human induced pluripotent stem cells (hiPSCs) it is essential to identify lines that are fully reprogrammed and of high quality with proven pluripotency in terms of differe...
    Speaker: Christian Freund
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
     
     
  • MAY 30, 2017 | 9:00 AM
    Protein and Cell Analysis Education Series featuring the Antibody Validation Forum
    Protein and Cell Analysis Education Series featuring the Antibody...
    Addressing the antibody reproducibility crisis: A panel discussion with key scientific leaders  Reproducibility and antibody validation standards are two significant challenges f...
    Speaker: Aled Edwards, PhD , Matt Baker , Anita Bandrowski, PhD , Paul Wallace, PhD , John Rogers, PhD , Christoph Hergersberg, PhD
    Presented at: Protein and Cell Analysis Education Series
    15
    APR 25, 2017 | 10:00 AM
    WEBINAR: Discover Potentially Predictive Immuno-Oncology Biomarkers using Next-Gen Sequencing
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    DATE: April 25, 2017TIME: 10:00am PT, 1:00pm ETImmunotherapy has emerged as one of the most promising options for the future treatment of a growing number of cancers and is to...
    Speaker: Fiona Hyland , Carl Morrison MD, DVM
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
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    MAR 21, 2017 | 10:00 AM
    WEBINAR: Application of combined RNA in situ hybridization and multiplex immunohistochemistry to unravel tumor heterogeneity in prostate cancer
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    DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By:      Prostate cancer is a complex disease with multiple tumors originating independent...
    Speaker: Nallasivam Palanisamy, PhD , Courtney Anderson, PhD
    Sponsored By: Novus Biologicals a Bio-Techne Brand
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    JAN 17, 2017 | 8:00 AM
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    Presented at: Abcam virtual exhibition: support and products to advance your research
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