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    Microscopy

    Microscopy: is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of microscopy: optical, electron, and scanning probe microscopy.

    Webinars

    • MAR 23, 2022 | 3:00 PM
      Standardization in Cannabis Pesticide Testing: Development of an LC-MS/MS and GC-MS/MS Method to Meet AOAC Standard Method Performance Requirements
      Standardization in Cannabis Pesticide Testing: Development of...
      Cannabis falls into a number of categories such as medicine, recreational drug, food source, and fiber, but it is first and foremost an agricultural crop. As such, Cannabis is subject to tre...
      Speaker: Thomas Barkley
      Presented at: Cannabis Sciences Virtual Event Series 2022
      2
      MAR 10, 2022 | 1:30 PM
      Utilization of the Luminex Platform to Discover and Develop Dual Toll-like Receptor 2 and 9 Antagonists for the Treatment of Neurodegenerative Diseases
      Utilization of the Luminex Platform to Discover and Develop Dual...
      Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
      Speaker: Diana L. Price, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      Sponsored By: Luminex - A DiaSorin Company
      1
      MAR 10, 2022 | 10:30 AM
      Automated 3D Light Sheet Microscopy: Opening New Dimensions in Neuroscience
      Automated 3D Light Sheet Microscopy: Opening New Dimensions in...
      The ability of light sheet microscopy to interrogate organoids, whole brain, and systems in 3D enables the study of complex neurological pathways, vasculature and disease models in unique wa...
      Speaker: Amanda Burke, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      Sponsored By: Miltenyi Biotec
      3
      MAR 09, 2022 | 10:00 AM
      Time-resolved electron microscopy: synaptic ultrastructure millisecond by millisecond with high-pressure freezing
      Time-resolved electron microscopy: synaptic ultrastructure millisecond...
      Date: March 09, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severe...
      Speaker: Shigeki Watanabe, Ph.D , Grant Kusick
      Sponsored By: Leica Microsystems
      5
      MAR 01, 2022 | 8:00 AM
      Histology Hacks For Cryosectioning
      Histology Hacks For Cryosectioning
      Date: March 01, 2022 Time: 08:00am (PST), 11:00am (EST) Histology laboratorians in the research world move fast, but those who perform cryosectioning know that these particular tissues requi...
      Speaker: Marla Rivera-Oliver, PhD
      Sponsored By: Leica Biosystems
      22
      FEB 23, 2022 | 1:30 PM
      Human-Certified 'omics Data to Power Drug Discovery
      Human-Certified 'omics Data to Power Drug Discovery
      Integrating external and internal ‘omics data is a key element of hypothesis generation, target identification, and biomarker prioritization when it comes to drug discovery. It is neve...
      Speaker: Joseph Pearson, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      Sponsored By: QIAGEN
      1
      DEC 14, 2021 | 7:00 AM
      Understanding SARS-CoV-2 variants by Cryo-EM
      Understanding SARS-CoV-2 variants by Cryo-EM
      Date: December 14, 2021 Time: 7:00am (PST), 10:00am (EST) Several fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have become the dominant circulating...
      Speaker: Bing Chen
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      10 1
      NOV 16, 2021 | 10:00 AM
      Towards a mechanistic understanding of motile and primary cilia with CLEM and cryo-electron tomography and expansion microscopy
      Towards a mechanistic understanding of motile and primary cilia...
      Date: November 16, 2021 Time: 10:00am PDT In this talk I will show how the power of modern electron microscopy (EM) techniques, coupled with light microscopy and expansion methods, can open...
      Speaker: Gaia Pigino
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      1
      NOV 04, 2021 | 8:00 AM
      Label 3Differently - how 3D-IF-validated antibodies provide clear signals from cleared tissues in large-scale 3D imaging
      Label 3Differently - how 3D-IF-validated antibodies provide clear...
      Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
      Speaker: Dr. Markus Habich
      Sponsored By: Miltenyi Biotec
      2
      NOV 03, 2021 | 6:00 AM
      Introduction to AI Image Analysis in Microscopy
      Introduction to AI Image Analysis in Microscopy
      Date: November 03, 2021 Time: 6:00am (PDT), 9:00am (EDT) Artificial intelligence (AI) technologies already play a major role in our everyday lives, such as smart speakers that understand you...
      Speaker: Quyen Tran, Ph.D.
      Sponsored By: Leica Microsystems
      10
      OCT 26, 2021 | 8:00 AM
      Maximizing tumor microenvironment analysis for TILs from limited patient samples
      Maximizing tumor microenvironment analysis for TILs from limited...
      Date: October 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) A complex interaction among heterogenous immune and tumor cells within the tumorous tissue not only influences tumor progression, but...
      Speaker: Dr. César Evaristo
      Sponsored By: Miltenyi Biotec
      5
      OCT 20, 2021 | 9:00 AM
      Membrane Proteins: From gene to cryo-EM structure with Thermo Fisher GeneArt and Salipro Biotech
      Membrane Proteins: From gene to cryo-EM structure with Thermo...
      Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
      Speaker: Ieva Drulyte, PhD , Michael Liss, PhD , Jens Frauenfeld, PhD
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      4
      SEP 23, 2021 | 8:00 AM
      Automated surveillance for deep characterization of the tumor microenvironment using ultra-high content imaging
      Automated surveillance for deep characterization of the tumor...
      Date: September 23, 2021 Time: 8:00am (PDT), 11:00am (EDT) The tumor microenvironment (TME) comprises complex cellular and structural features. The processes and interactions within the TME...
      Speaker: Dr. Telma Santos , Dr. Nizar Yousif
      Sponsored By: Miltenyi Biotec
      3 1
      SEP 09, 2021 | 11:00 AM
      Cryogenic Electron Microscopy of Beam and Air-Sensitive Materials
      Cryogenic Electron Microscopy of Beam and Air-Sensitive Materials
      Date: September 9, 2021 Time: 11:00am (PDT), 12:00pm (EDT) Advances in cryogenic electron microscopy (cryo-EM), primarily driven by the life sciences, have emerged as powerful techniques for...
      Speaker: Daniel Long , John Watt
      Sponsored By: Leica Microsystems
      4
      AUG 26, 2021 | 7:00 AM
      Deciphering the cross-talk between immunosuppressive cells in pancreatic cancer using 3D light sheet microscopy
      Deciphering the cross-talk between immunosuppressive cells in...
      Date: August 26, 2021 Time: 7:00am (PDT), 10:00am (EDT) Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. In t...
      Speaker: Carole Siret, Ph.D.
      Sponsored By: Miltenyi Biotec
      9
      JUL 27, 2021 | 9:00 AM
      Cryo-EM in discovery and rational engineering of biologics
      Cryo-EM in discovery and rational engineering of biologics
      Date: July 27, 2021 Time: 9:00am PDT Dr. Yuri Iozzo presents "An integrated structural biology platform specialized for sub-100 kDa protein complexes to support biologics discovery and...
      Speaker: Yuri Iozzo , Dan Cannon
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      5
      JUN 29, 2021 | 11:00 AM
      Advancing Cellular Ultrastructure Research with Freeze-Fracture and Freeze-Etching
      Advancing Cellular Ultrastructure Research with Freeze-Fracture...
      Date: June 29, 2021 Time: 11:00am (PDT), 02:00pm (EDT) Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the...
      Speaker: Evan Krystofiak , Seth Villarreal
      Sponsored By: Leica Microsystems
      9 1
      JUN 24, 2021 | 9:00 AM
      Structural Oncology - Fighting Cancer with Cryo-EM
      Structural Oncology - Fighting Cancer with Cryo-EM
      Date: June 24, 2021 Time: 9:00am PDT Currently, there are insufficient therapies to fully eradicate human cancer or predict who it will strike. Rational-drug design based on structural insi...
      Speaker: Deb Kelly
      Sponsored By: Thermo Fisher Scientific
      5
      JUN 16, 2021 | 8:00 AM
      Simplicity that defies complexity - the MACSimaâ„¢ Platform for ultrahigh-content imaging
      Simplicity that defies complexity - the MACSimaâ„¢ Platform for...
      Date: June 16, 2021 Time: 8:00am PDT The MACSima™ Imaging Platform is the only complete solution for ultrahigh-content imaging of hundreds of markers, allowing you to understand the tu...
      Speaker: Dr. Ali Kinkhabwala , Dr. Markus Habich
      Sponsored By: Miltenyi Biotec
      7
      JUN 15, 2021 | 10:00 AM
      Single cell & label free binding affinity: applications with Genentech
      Single cell & label free binding affinity: applications with Genentech
      Date: June 15, 2021 Time: 10:00am (PDT), 1:00pm (EDT) SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time binding affinity and kinetics of...
      Speaker: Elaine Mai, MS , Dr. Shijie Wu
      Sponsored By: Biosensing Instrument
      3
      JUN 10, 2021 | 8:00 AM
      Capture Life As It Happens - The New Leica Nano Workflow
      Capture Life As It Happens - The New Leica Nano Workflow
      Date: June 10, 2021 Time: 8:00am (PDT), 11:00am (EDT) With the new Leica Nano Workflow, searching for the needle in the haystack is a thing of the past. Take advantage of correlative light a...
      Speaker: Dr. Julia Koenig
      Sponsored By: Leica Microsystems
      3
      JUN 09, 2021 | 7:00 AM
      Preventing cell misidentification in your daily lab routine
      Preventing cell misidentification in your daily lab routine
      Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
      Speaker: Gabriela Saldanha , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      40 3
      JUN 03, 2021 | 7:00 AM
      Elevating Laboratory Leadership: Transforming Your Career and Laboratory Through Collaboration
      Elevating Laboratory Leadership: Transforming Your Career and...
      DATE: June 03, 2021 TIME: 7:00am PDT Dr. Anne Kornreich will discuss her career journey in laboratory medicine that began with hematology and progressed to a leadership role through addition...
      Speaker: Dr. Anne Kornreich
      Sponsored By: Abbott
      17
      MAY 19, 2021 | 8:00 AM
      Turn on the lights in cryo-FIB tomography sample preparation
      Turn on the lights in cryo-FIB tomography sample preparation
      Date: May 19, 2021 Time: 8:00am PDT Cellular cryo-electron tomography is a high-resolution technique that enables imaging of the molecular machinery of a cell at close-to-native conditions....
      Speaker: Alex Rigort
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      10 1
    MAR 23, 2022 | 3:00 PM
    Standardization in Cannabis Pesticide Testing: Development of an LC-MS/MS and GC-MS/MS Method to Meet AOAC Standard Method Performance Requirements
    Standardization in Cannabis Pesticide Testing: Development of...
    Cannabis falls into a number of categories such as medicine, recreational drug, food source, and fiber, but it is first and foremost an agricultural crop. As such, Cannabis is subject to tre...
    Speaker: Thomas Barkley
    Presented at: Cannabis Sciences Virtual Event Series 2022
    2
    MAR 10, 2022 | 1:30 PM
    Utilization of the Luminex Platform to Discover and Develop Dual Toll-like Receptor 2 and 9 Antagonists for the Treatment of Neurodegenerative Diseases
    Utilization of the Luminex Platform to Discover and Develop Dual...
    Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
    Speaker: Diana L. Price, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    Sponsored By: Luminex - A DiaSorin Company
    1
    MAR 10, 2022 | 10:30 AM
    Automated 3D Light Sheet Microscopy: Opening New Dimensions in Neuroscience
    Automated 3D Light Sheet Microscopy: Opening New Dimensions in...
    The ability of light sheet microscopy to interrogate organoids, whole brain, and systems in 3D enables the study of complex neurological pathways, vasculature and disease models in unique wa...
    Speaker: Amanda Burke, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    Sponsored By: Miltenyi Biotec
    3
    MAR 09, 2022 | 10:00 AM
    Time-resolved electron microscopy: synaptic ultrastructure millisecond by millisecond with high-pressure freezing
    Time-resolved electron microscopy: synaptic ultrastructure millisecond...
    Date: March 09, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severe...
    Speaker: Shigeki Watanabe, Ph.D , Grant Kusick
    Sponsored By: Leica Microsystems
    5
    MAR 01, 2022 | 8:00 AM
    Histology Hacks For Cryosectioning
    Histology Hacks For Cryosectioning
    Date: March 01, 2022 Time: 08:00am (PST), 11:00am (EST) Histology laboratorians in the research world move fast, but those who perform cryosectioning know that these particular tissues requi...
    Speaker: Marla Rivera-Oliver, PhD
    Sponsored By: Leica Biosystems
    22
     
     
  • FEB 23, 2022 | 1:30 PM
    Human-Certified 'omics Data to Power Drug Discovery
    Human-Certified 'omics Data to Power Drug Discovery
    Integrating external and internal ‘omics data is a key element of hypothesis generation, target identification, and biomarker prioritization when it comes to drug discovery. It is neve...
    Speaker: Joseph Pearson, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    Sponsored By: QIAGEN
    1
    DEC 14, 2021 | 7:00 AM
    Understanding SARS-CoV-2 variants by Cryo-EM
    Understanding SARS-CoV-2 variants by Cryo-EM
    Date: December 14, 2021 Time: 7:00am (PST), 10:00am (EST) Several fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have become the dominant circulating...
    Speaker: Bing Chen
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    10 1
    NOV 16, 2021 | 10:00 AM
    Towards a mechanistic understanding of motile and primary cilia with CLEM and cryo-electron tomography and expansion microscopy
    Towards a mechanistic understanding of motile and primary cilia...
    Date: November 16, 2021 Time: 10:00am PDT In this talk I will show how the power of modern electron microscopy (EM) techniques, coupled with light microscopy and expansion methods, can open...
    Speaker: Gaia Pigino
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    1
    NOV 04, 2021 | 8:00 AM
    Label 3Differently - how 3D-IF-validated antibodies provide clear signals from cleared tissues in large-scale 3D imaging
    Label 3Differently - how 3D-IF-validated antibodies provide clear...
    Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
    Speaker: Dr. Markus Habich
    Sponsored By: Miltenyi Biotec
    2
    NOV 03, 2021 | 6:00 AM
    Introduction to AI Image Analysis in Microscopy
    Introduction to AI Image Analysis in Microscopy
    Date: November 03, 2021 Time: 6:00am (PDT), 9:00am (EDT) Artificial intelligence (AI) technologies already play a major role in our everyday lives, such as smart speakers that understand you...
    Speaker: Quyen Tran, Ph.D.
    Sponsored By: Leica Microsystems
    10
     
     
  • OCT 26, 2021 | 8:00 AM
    Maximizing tumor microenvironment analysis for TILs from limited patient samples
    Maximizing tumor microenvironment analysis for TILs from limited...
    Date: October 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) A complex interaction among heterogenous immune and tumor cells within the tumorous tissue not only influences tumor progression, but...
    Speaker: Dr. César Evaristo
    Sponsored By: Miltenyi Biotec
    5
    OCT 20, 2021 | 9:00 AM
    Membrane Proteins: From gene to cryo-EM structure with Thermo Fisher GeneArt and Salipro Biotech
    Membrane Proteins: From gene to cryo-EM structure with Thermo...
    Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
    Speaker: Ieva Drulyte, PhD , Michael Liss, PhD , Jens Frauenfeld, PhD
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    4
    SEP 23, 2021 | 8:00 AM
    Automated surveillance for deep characterization of the tumor microenvironment using ultra-high content imaging
    Automated surveillance for deep characterization of the tumor...
    Date: September 23, 2021 Time: 8:00am (PDT), 11:00am (EDT) The tumor microenvironment (TME) comprises complex cellular and structural features. The processes and interactions within the TME...
    Speaker: Dr. Telma Santos , Dr. Nizar Yousif
    Sponsored By: Miltenyi Biotec
    3 1
    SEP 09, 2021 | 11:00 AM
    Cryogenic Electron Microscopy of Beam and Air-Sensitive Materials
    Cryogenic Electron Microscopy of Beam and Air-Sensitive Materials
    Date: September 9, 2021 Time: 11:00am (PDT), 12:00pm (EDT) Advances in cryogenic electron microscopy (cryo-EM), primarily driven by the life sciences, have emerged as powerful techniques for...
    Speaker: Daniel Long , John Watt
    Sponsored By: Leica Microsystems
    4
    AUG 26, 2021 | 7:00 AM
    Deciphering the cross-talk between immunosuppressive cells in pancreatic cancer using 3D light sheet microscopy
    Deciphering the cross-talk between immunosuppressive cells in...
    Date: August 26, 2021 Time: 7:00am (PDT), 10:00am (EDT) Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. In t...
    Speaker: Carole Siret, Ph.D.
    Sponsored By: Miltenyi Biotec
    9
     
     
  • JUL 27, 2021 | 9:00 AM
    Cryo-EM in discovery and rational engineering of biologics
    Cryo-EM in discovery and rational engineering of biologics
    Date: July 27, 2021 Time: 9:00am PDT Dr. Yuri Iozzo presents "An integrated structural biology platform specialized for sub-100 kDa protein complexes to support biologics discovery and...
    Speaker: Yuri Iozzo , Dan Cannon
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    5
    JUN 29, 2021 | 11:00 AM
    Advancing Cellular Ultrastructure Research with Freeze-Fracture and Freeze-Etching
    Advancing Cellular Ultrastructure Research with Freeze-Fracture...
    Date: June 29, 2021 Time: 11:00am (PDT), 02:00pm (EDT) Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the...
    Speaker: Evan Krystofiak , Seth Villarreal
    Sponsored By: Leica Microsystems
    9 1
    JUN 24, 2021 | 9:00 AM
    Structural Oncology - Fighting Cancer with Cryo-EM
    Structural Oncology - Fighting Cancer with Cryo-EM
    Date: June 24, 2021 Time: 9:00am PDT Currently, there are insufficient therapies to fully eradicate human cancer or predict who it will strike. Rational-drug design based on structural insi...
    Speaker: Deb Kelly
    Sponsored By: Thermo Fisher Scientific
    5
    JUN 16, 2021 | 8:00 AM
    Simplicity that defies complexity - the MACSimaâ„¢ Platform for ultrahigh-content imaging
    Simplicity that defies complexity - the MACSimaâ„¢ Platform for...
    Date: June 16, 2021 Time: 8:00am PDT The MACSima™ Imaging Platform is the only complete solution for ultrahigh-content imaging of hundreds of markers, allowing you to understand the tu...
    Speaker: Dr. Ali Kinkhabwala , Dr. Markus Habich
    Sponsored By: Miltenyi Biotec
    7
    JUN 15, 2021 | 10:00 AM
    Single cell & label free binding affinity: applications with Genentech
    Single cell & label free binding affinity: applications with Genentech
    Date: June 15, 2021 Time: 10:00am (PDT), 1:00pm (EDT) SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time binding affinity and kinetics of...
    Speaker: Elaine Mai, MS , Dr. Shijie Wu
    Sponsored By: Biosensing Instrument
    3
     
     
  • JUN 10, 2021 | 8:00 AM
    Capture Life As It Happens - The New Leica Nano Workflow
    Capture Life As It Happens - The New Leica Nano Workflow
    Date: June 10, 2021 Time: 8:00am (PDT), 11:00am (EDT) With the new Leica Nano Workflow, searching for the needle in the haystack is a thing of the past. Take advantage of correlative light a...
    Speaker: Dr. Julia Koenig
    Sponsored By: Leica Microsystems
    3
    JUN 09, 2021 | 7:00 AM
    Preventing cell misidentification in your daily lab routine
    Preventing cell misidentification in your daily lab routine
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    Speaker: Gabriela Saldanha , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    40 3
    JUN 03, 2021 | 7:00 AM
    Elevating Laboratory Leadership: Transforming Your Career and Laboratory Through Collaboration
    Elevating Laboratory Leadership: Transforming Your Career and...
    DATE: June 03, 2021 TIME: 7:00am PDT Dr. Anne Kornreich will discuss her career journey in laboratory medicine that began with hematology and progressed to a leadership role through addition...
    Speaker: Dr. Anne Kornreich
    Sponsored By: Abbott
    17
    MAY 19, 2021 | 8:00 AM
    Turn on the lights in cryo-FIB tomography sample preparation
    Turn on the lights in cryo-FIB tomography sample preparation
    Date: May 19, 2021 Time: 8:00am PDT Cellular cryo-electron tomography is a high-resolution technique that enables imaging of the molecular machinery of a cell at close-to-native conditions....
    Speaker: Alex Rigort
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    10 1
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