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    Nuclear DNA

    Nuclear DNA is a molecule with a double helix structure that is contained within the nuclei of eukaryotic cells. Nucleic DNA encodes the vast majority of the organism's genome, or the genetic information inherited from each parent.

    Webinars

    • AUG 19, 2021 | 8:00 AM
      Investigating the effect of diabetes on bone quality via changes in gene expression of glycation and bone remodeling markers in osteocytes
      Investigating the effect of diabetes on bone quality via changes...
      DATE: August 19, 2020 TIME: 8:00am PT, 11:00pm ET Type 2 diabetes mellitus (T2D) is associated with an increased risk of osteoporotic fractures. Several factors have been identified as being...
      Speaker: Rachana Vaidya
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      APR 20, 2021 | 12:00 AM
      Measurement of DNA Methylation and Nuclear Organization with Nanopore Sequencing
      Measurement of DNA Methylation and Nuclear Organization with Nanopore...
      Nanopore sequencing has enormous potential in epigenetic applications; unlike traditional sequencing-by-synthesis technologies, it can distinguish covalently modified nucleotides directly th...
      Speaker: Roham Razaghi, PhD Candidate
      Presented at: Genetics Week Virtual Event Series 2021
      1
      MAR 16, 2021 | 10:00 AM
      Getting started with Cryo-EM: Writing the NIH Shared Instrumentation Grant Application - Strategies for Success
      Getting started with Cryo-EM: Writing the NIH Shared Instrumentation...
      Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
      Speaker: Christopher Dant, PhD
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      7
      FEB 24, 2021 | 7:00 AM
      DeepCLIP: Predicting the effect of mutations on protein-RNA binding with deep learning
      DeepCLIP: Predicting the effect of mutations on protein-RNA binding...
      Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
      Speaker: Thomas Doktor, PhD.
      Sponsored By: GenScript
      12
      SEP 09, 2020 | 12:00 AM
      Immune-derived extracellular traps in COVID-19 and other infections
      Immune-derived extracellular traps in COVID-19 and other infections
      As a response to various inflammatory stimuli, neutrophils and macrophages expel a mixture of their nuclear and granular elements in the form of extracellular traps (ETs). These web-like sub...
      Speaker: Imre Varju, MD, PhD, MPH
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      AUG 06, 2020 | 10:00 AM
      Part VIII: The "Real" Nuclear Physics: Tracking Genome Dynamics in Time and Space
      Part VIII: The "Real" Nuclear Physics: Tracking Genome Dynamics...
      Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
      Speaker: Massa Shoura, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 02, 2020 | 12:15 PM
      Microsatellite instability analysis for studying immunotherapy and Lynch syndrome-related cancers
      Microsatellite instability analysis for studying immunotherapy...
      Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
      Speaker: Charles Baudo, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      MAY 08, 2020 | 8:00 AM
      Development of a novel molecular MSI assay with an expanded panel and automated MSI status calling
      Development of a novel molecular MSI assay with an expanded panel...
      DATE: May 8, 2020 TIME: 8:00am PT, 11:00am ET Microsatellite instability (MSI) is the condition of genetic hypermutability that results from impaired DNA mismatch repair (MMR). Studies indic...
      Speaker: Charles Baudo, Ph.D.
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      8 2
      MAY 06, 2020 | 7:30 AM
      Keynote Presentation: Complexities of characterizing mineral particle toxicity at the pulmonary interface
      Keynote Presentation: Complexities of characterizing mineral particle...
      The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
      Speaker: Christopher Weis, PhD, DABT
      Presented at: Forensic Sciences Virtual Event Series 2020
      1
      APR 14, 2020 | 9:00 AM
      Gibco Cell Culture Heroes: Work From Home Edition
      Gibco Cell Culture Heroes: Work From Home Edition
      DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
      Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12 1
      JAN 31, 2019 | 7:30 AM
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      OCT 11, 2018 | 1:30 PM
      Breast Cancer as a Global Disease: Are We Up to The Challenge?
      Breast Cancer as a Global Disease: Are We Up to The Challenge?
      As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
      Speaker: Benjamin Anderson, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      3
      OCT 11, 2018 | 12:00 PM
      Lung Cancer Evolution and Immune Escape
      Lung Cancer Evolution and Immune Escape
      Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
      Speaker: Nicholas McGranahan, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      APR 27, 2018 | 10:00 AM
      Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
      Investigating DNA repair mechanisms in hypoxic brain tumours and...
      DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
      Speaker: Sophie Cowman
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 4
    AUG 19, 2021 | 8:00 AM
    Investigating the effect of diabetes on bone quality via changes in gene expression of glycation and bone remodeling markers in osteocytes
    Investigating the effect of diabetes on bone quality via changes...
    DATE: August 19, 2020 TIME: 8:00am PT, 11:00pm ET Type 2 diabetes mellitus (T2D) is associated with an increased risk of osteoporotic fractures. Several factors have been identified as being...
    Speaker: Rachana Vaidya
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    APR 20, 2021 | 12:00 AM
    Measurement of DNA Methylation and Nuclear Organization with Nanopore Sequencing
    Measurement of DNA Methylation and Nuclear Organization with Nanopore...
    Nanopore sequencing has enormous potential in epigenetic applications; unlike traditional sequencing-by-synthesis technologies, it can distinguish covalently modified nucleotides directly th...
    Speaker: Roham Razaghi, PhD Candidate
    Presented at: Genetics Week Virtual Event Series 2021
    1
    MAR 16, 2021 | 10:00 AM
    Getting started with Cryo-EM: Writing the NIH Shared Instrumentation Grant Application - Strategies for Success
    Getting started with Cryo-EM: Writing the NIH Shared Instrumentation...
    Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
    Speaker: Christopher Dant, PhD
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    7
    FEB 24, 2021 | 7:00 AM
    DeepCLIP: Predicting the effect of mutations on protein-RNA binding with deep learning
    DeepCLIP: Predicting the effect of mutations on protein-RNA binding...
    Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
    Speaker: Thomas Doktor, PhD.
    Sponsored By: GenScript
    12
    SEP 09, 2020 | 12:00 AM
    Immune-derived extracellular traps in COVID-19 and other infections
    Immune-derived extracellular traps in COVID-19 and other infections
    As a response to various inflammatory stimuli, neutrophils and macrophages expel a mixture of their nuclear and granular elements in the form of extracellular traps (ETs). These web-like sub...
    Speaker: Imre Varju, MD, PhD, MPH
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • AUG 06, 2020 | 10:00 AM
    Part VIII: The "Real" Nuclear Physics: Tracking Genome Dynamics in Time and Space
    Part VIII: The "Real" Nuclear Physics: Tracking Genome Dynamics...
    Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
    Speaker: Massa Shoura, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 02, 2020 | 12:15 PM
    Microsatellite instability analysis for studying immunotherapy and Lynch syndrome-related cancers
    Microsatellite instability analysis for studying immunotherapy...
    Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
    Speaker: Charles Baudo, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    MAY 08, 2020 | 8:00 AM
    Development of a novel molecular MSI assay with an expanded panel and automated MSI status calling
    Development of a novel molecular MSI assay with an expanded panel...
    DATE: May 8, 2020 TIME: 8:00am PT, 11:00am ET Microsatellite instability (MSI) is the condition of genetic hypermutability that results from impaired DNA mismatch repair (MMR). Studies indic...
    Speaker: Charles Baudo, Ph.D.
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    8 2
    MAY 06, 2020 | 7:30 AM
    Keynote Presentation: Complexities of characterizing mineral particle toxicity at the pulmonary interface
    Keynote Presentation: Complexities of characterizing mineral particle...
    The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
    Speaker: Christopher Weis, PhD, DABT
    Presented at: Forensic Sciences Virtual Event Series 2020
    1
    APR 14, 2020 | 9:00 AM
    Gibco Cell Culture Heroes: Work From Home Edition
    Gibco Cell Culture Heroes: Work From Home Edition
    DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
    Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12 1
     
     
  • JAN 31, 2019 | 7:30 AM
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    OCT 11, 2018 | 1:30 PM
    Breast Cancer as a Global Disease: Are We Up to The Challenge?
    Breast Cancer as a Global Disease: Are We Up to The Challenge?
    As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
    Speaker: Benjamin Anderson, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    3
    OCT 11, 2018 | 12:00 PM
    Lung Cancer Evolution and Immune Escape
    Lung Cancer Evolution and Immune Escape
    Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
    Speaker: Nicholas McGranahan, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
     
     
  • OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    APR 27, 2018 | 10:00 AM
    Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
    Investigating DNA repair mechanisms in hypoxic brain tumours and...
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    Speaker: Sophie Cowman
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 4
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