Pharmacogenomics: the study of the role of the genome in drug response. Its name reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects his/her response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with pharmacokinetics (drug absorption, distribution, metabolism, and elimination) and pharmacodynamics.
Pharmacogenomics has emerged as an early use case of precision medicine. Delivering this new clinical data to clinicians in a ready to use format can be challenging. This talk wil...
Precision medicine allows for prediction of drug response and tailoring drug therapy based on genetic variability. This talk will provide examples of precision medicine initiatives at the Uni...
DATE: December 5, 2017TIME: 08:00am PST, 10:00am CST, 11:00am EST, 5:00pm CET Recently there has been a resurgence of Syphilis infections over the last several years with rates...
Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines. Pain does not go away, and may intensify...
DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
DATE: June 27, 2017TIME: 8:00am PT, 11:00am ETThe purpose of this study is to identify genetic variants that influence cellular responses, and patterns of M.tb infection and growth in h...
SMRT Sequencing is a DNA sequencing technology characterized by long read lengths and high consensus accuracy, regardless of the sequence complexity or GC content of the DNA sample. These cha...
Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
DATE: December 6, 2016
TIME: 8:00am PT, 11:00am ET
Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality in health care. In the US alone, an est...
Breast cancer is a complex heterogeneous disease, with each subtype characterized by distinct clinical features and molecular alterations. The heterogeneity of breast cancer has presented mas...
Emerging technologies facilitate basic science research, but their value in regulatory applications requires rigorous assessment and consensus within the research community. Next-generation s...
The advent of the microarray technology in 2000 has paved the way for advanced translational research methods that use molecular markers such as microRNA, proteins, metabolites and copy numbe...
Personalised Healthcare is essential to AstraZeneca’s approach to drug development and is adopted by more than 80% of drug products in clinical development. Selection of the right patie...
This lecture will provide attendees with the knowledge and skills to bring on new clinical laboratory tests in clinical chemistry and molecular diagnostics. The lecture will provide a general...
Learning Objectives for this presentation -
(1) Understand how human genetics can contribute to drug discovery and development.
(2) Understand the role of biomarkers and clinical proof-...
For personalized genomic medicine (PGM) to be readily adopted into clinical practice, there is a need for a multidisciplinary team, and a need to educate health care professionals and the...
Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
Pharmcogenomics (PGx) is the 2nd potential clinical application of genomic medicine, preceded by genomic application for cancer. In the recently published, 2012 Institute of Medicine report o...
Genome sequencing technologies have enabled a rapid expansion into understanding cancer biology, drug development, and treatment resistance. Research in our laboratory has focused on the app...
The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
Anticoagulation therapy is frequently employed to prevent stroke in patients with atrial fibrillation, prophylaxis of venous thromboembolism and pulmonary embolism in patients with prosthetic...
The goal of personalized medicine is to customize healthcare to the individual patient. Pharmacogenomics, the analysis of how a patient's genetic makeup affects the individual's response to c...
Increasingly genome sequence knowledge is unraveling the complexity of rare Mendelian disorders offering hope for our children's medical care through better disease diagnosis and ultimately p...
As a component of individualized medicine, pharmacogenetics (PGx) focuses on how genetic factors influence individual responses to specific medications. The clinical goals of pharmacogenetics...
Pharmacogenomics has emerged as an early use case of precision medicine. Delivering this new clinical data to clinicians in a ready to use format can be challenging. This talk wil...
Precision medicine allows for prediction of drug response and tailoring drug therapy based on genetic variability. This talk will provide examples of precision medicine initiatives at the Uni...
DATE: December 5, 2017TIME: 08:00am PST, 10:00am CST, 11:00am EST, 5:00pm CET Recently there has been a resurgence of Syphilis infections over the last several years with rates...
Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines. Pain does not go away, and may intensify...
DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
DATE: June 27, 2017TIME: 8:00am PT, 11:00am ETThe purpose of this study is to identify genetic variants that influence cellular responses, and patterns of M.tb infection and growth in h...
SMRT Sequencing is a DNA sequencing technology characterized by long read lengths and high consensus accuracy, regardless of the sequence complexity or GC content of the DNA sample. These cha...
Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
DATE: December 6, 2016
TIME: 8:00am PT, 11:00am ET
Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality in health care. In the US alone, an est...
Breast cancer is a complex heterogeneous disease, with each subtype characterized by distinct clinical features and molecular alterations. The heterogeneity of breast cancer has presented mas...
Emerging technologies facilitate basic science research, but their value in regulatory applications requires rigorous assessment and consensus within the research community. Next-generation s...
The advent of the microarray technology in 2000 has paved the way for advanced translational research methods that use molecular markers such as microRNA, proteins, metabolites and copy numbe...
Personalised Healthcare is essential to AstraZeneca’s approach to drug development and is adopted by more than 80% of drug products in clinical development. Selection of the right patie...
This lecture will provide attendees with the knowledge and skills to bring on new clinical laboratory tests in clinical chemistry and molecular diagnostics. The lecture will provide a general...
Learning Objectives for this presentation -
(1) Understand how human genetics can contribute to drug discovery and development.
(2) Understand the role of biomarkers and clinical proof-...
For personalized genomic medicine (PGM) to be readily adopted into clinical practice, there is a need for a multidisciplinary team, and a need to educate health care professionals and the...
Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
Pharmcogenomics (PGx) is the 2nd potential clinical application of genomic medicine, preceded by genomic application for cancer. In the recently published, 2012 Institute of Medicine report o...
Genome sequencing technologies have enabled a rapid expansion into understanding cancer biology, drug development, and treatment resistance. Research in our laboratory has focused on the app...
The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
Anticoagulation therapy is frequently employed to prevent stroke in patients with atrial fibrillation, prophylaxis of venous thromboembolism and pulmonary embolism in patients with prosthetic...
The goal of personalized medicine is to customize healthcare to the individual patient. Pharmacogenomics, the analysis of how a patient's genetic makeup affects the individual's response to c...
Increasingly genome sequence knowledge is unraveling the complexity of rare Mendelian disorders offering hope for our children's medical care through better disease diagnosis and ultimately p...
As a component of individualized medicine, pharmacogenetics (PGx) focuses on how genetic factors influence individual responses to specific medications. The clinical goals of pharmacogenetics...
Follow
