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    Preclinical Imaging

    Preclinical imaging is the visualization of living animals for research purposes or to develop a modern and translational biomedical research. Preclinical imaging has a critical role in phenotyping, in drug discovery, and in providing a basic understanding of mechanisms of disease.

    Webinars

    • JAN 01, 2020 | 6:00 AM
      Human Tissue models for better therapies
      Human Tissue models for better therapies
      The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
      Speaker: Sebastiaan Trietsch, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      NOV 08, 2019 | 8:00 AM
      Polygenic Risk Score analysis for Alzheimer's disease risk
      Polygenic Risk Score analysis for Alzheimer's disease risk
      DATE: November 8, 2019TIME: 8:00am PT, 11:00am ET...
      Speaker: Richard Pither, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      6
      SEP 19, 2019 | 9:00 AM
      Automated Multiplex Immunofluorescence
      Automated Multiplex Immunofluorescence
      DATE: September 19, 2019TIME: 9:00am PT, 12:00pm ET Cancer research continues to push the boundaries with new advancements in tissue analysis and biomarker detection. Now, more...
      Speaker: Bethany Remeniuk, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
      Sponsored By: Leica Biosystems
      6
      JUL 30, 2019 | 10:00 AM
      Validating antibodies for research applications in IHC
      Validating antibodies for research applications in IHC
      DATE: July 30, 2019TIME: 10:00am PT/ 1:00pm ET The importance of building a validation structure within your lab cannot be overstated. Once in place, the ability to identify high...
      Speaker: Will Howat, PhD , Damian Cockfield
      Sponsored By: Leica Biosystems
      12
      MAR 14, 2019 | 9:00 AM
      A Gene Expression Based Screening Platform for Mouse Models of Late-Onset Alzheimer's Disease
      A Gene Expression Based Screening Platform for Mouse Models of...
      Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
      Speaker: Greg Carter, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      2
      FEB 14, 2019 | 7:30 AM
      Keynote Presentation: A Comparative Approach to Oncology Drug Development: Integrating Canine Models
      Keynote Presentation: A Comparative Approach to Oncology Drug...
      Comparative oncology is the study of naturally-occurring cancers in pet animals (mainly dogs) to broaden and deepen our collective understanding of cancers in both companion species and human...
      Speaker: Amy LeBlanc, DVM DACVIM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      FEB 14, 2019 | 6:00 AM
      Connected Data: Linking Pre-Clinical Data to Commercial Outcomes for Patients Today
      Connected Data: Linking Pre-Clinical Data to Commercial Outcomes...
      As we look towards data to help generate insight and analytics across the entire drug discovery value chain, learn how interconnected data is from the various stages of preclinical, clinical,...
      Speaker: Wu Wu
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      2
      FEB 13, 2019 | 1:30 PM
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
      Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5
      FEB 13, 2019 | 10:30 AM
      Qualitative, Biased, Personal and Speculative Remarks on Digitization, Digitalization & Digital Transformation
      Qualitative, Biased, Personal and Speculative Remarks on Digitization,...
      A collection of opinions, questions and other assorted thoughts about the intersection of these developing technologies and preclinical studies primarily focused on the early discovery (as op...
      Speaker: Sean Maguire, VMD, MS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      4
      FEB 13, 2019 | 10:30 AM
      Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
      Accurate Clinical Concentration-Response Predictions for Cardiac...
      Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
      Speaker: Weihsueh Chiu, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5 1
      FEB 13, 2019 | 9:00 AM
      Making Data Fly in Formation
      Making Data Fly in Formation
      In biomedical research, data should be treated as first-class corporate assets--they were expensive to create, they are expensive to maintain, and they have future business value. The petabyt...
      Speaker: Chuck Donnelly , Julie Morrison
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      1
      FEB 13, 2019 | 7:30 AM
      Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
      Keynote Presentation: Modernizing Drug Development Through Digital...
      Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      6
      DEC 10, 2018 | 10:00 PM
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
      DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
      Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
      Sponsored By: Revvity
      4 1
      DEC 06, 2018 | 8:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      2
      DEC 06, 2018 | 1:00 AM
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
      Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
      DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
      Speaker: Rob van 't Hof, BSc, MSc, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      8
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      SEP 20, 2018 | 8:00 AM
      Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
      Cardiovascular Disease: Applying MRI to study atherosclerosis,...
       DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
      Speaker: Claudia Calcagno Mani, MD, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      10
      SEP 20, 2018 | 1:00 AM
      Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
      Cardiovascular Disease: Applying MRI to study atherosclerosis,...
      DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
      Speaker: Claudia Calcagno Mani, MD, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      6 1
      JUN 26, 2018 | 9:00 AM
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
      Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
      Speaker: Laura Schaevitz, PhD
      Sponsored By: Vium
      6
      JUN 07, 2018 | 7:00 AM
      How microCT Can Provide Insight into Dynamic Disease Processes
      How microCT Can Provide Insight into Dynamic Disease Processes
      DATE: June 7, 2018TIME: 07:00AM PDT, 4:00PM CESTIn this webinar, Prof. Greetje Vande Velde will give an overview of her work, which involves lung and brain infections.  Dr Vande Ve...
      Speaker: Greetje Vande Velde
      Sponsored By: Bruker Microbiology & Diagnostics
      4 1
      MAY 30, 2018 | 10:30 AM
      Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
      Inhibitors of NSD2 Discovered by High-Throughput Screening with...
      NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
      Speaker: Nathan Coussens, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      1
      APR 06, 2018 | 9:00 AM
      Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
      Multiplex Immunofluorescence Profiling of Tumor Biopsies Using...
      DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
      Speaker: Helen Snyder, PhD , Marie-Louise Loupart, PhD
      Sponsored By: Leica Biosystems
      8
      FEB 08, 2018 | 1:30 PM
      Applications of Preclinical Translational Imaging Technologies for Improved Modeling and Decision Making
      Applications of Preclinical Translational Imaging Technologies...
      Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
      Speaker: Paul Makidon, DVM, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      3
      FEB 08, 2018 | 7:30 AM
      Modernization of Animal Studies
      Modernization of Animal Studies
      There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
      Speaker: Natalie Bratcher , Sean Maguire, VMD, MS, DACLAM , Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      2
    JAN 01, 2020 | 6:00 AM
    Human Tissue models for better therapies
    Human Tissue models for better therapies
    The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
    Speaker: Sebastiaan Trietsch, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    NOV 08, 2019 | 8:00 AM
    Polygenic Risk Score analysis for Alzheimer's disease risk
    Polygenic Risk Score analysis for Alzheimer's disease risk
    DATE: November 8, 2019TIME: 8:00am PT, 11:00am ET...
    Speaker: Richard Pither, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    6
    SEP 19, 2019 | 9:00 AM
    Automated Multiplex Immunofluorescence
    Automated Multiplex Immunofluorescence
    DATE: September 19, 2019TIME: 9:00am PT, 12:00pm ET Cancer research continues to push the boundaries with new advancements in tissue analysis and biomarker detection. Now, more...
    Speaker: Bethany Remeniuk, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
    Sponsored By: Leica Biosystems
    6
    JUL 30, 2019 | 10:00 AM
    Validating antibodies for research applications in IHC
    Validating antibodies for research applications in IHC
    DATE: July 30, 2019TIME: 10:00am PT/ 1:00pm ET The importance of building a validation structure within your lab cannot be overstated. Once in place, the ability to identify high...
    Speaker: Will Howat, PhD , Damian Cockfield
    Sponsored By: Leica Biosystems
    12
    MAR 14, 2019 | 9:00 AM
    A Gene Expression Based Screening Platform for Mouse Models of Late-Onset Alzheimer's Disease
    A Gene Expression Based Screening Platform for Mouse Models of...
    Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
    Speaker: Greg Carter, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    2
     
     
  • FEB 14, 2019 | 7:30 AM
    Keynote Presentation: A Comparative Approach to Oncology Drug Development: Integrating Canine Models
    Keynote Presentation: A Comparative Approach to Oncology Drug...
    Comparative oncology is the study of naturally-occurring cancers in pet animals (mainly dogs) to broaden and deepen our collective understanding of cancers in both companion species and human...
    Speaker: Amy LeBlanc, DVM DACVIM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
    FEB 14, 2019 | 6:00 AM
    Connected Data: Linking Pre-Clinical Data to Commercial Outcomes for Patients Today
    Connected Data: Linking Pre-Clinical Data to Commercial Outcomes...
    As we look towards data to help generate insight and analytics across the entire drug discovery value chain, learn how interconnected data is from the various stages of preclinical, clinical,...
    Speaker: Wu Wu
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    2
    FEB 13, 2019 | 1:30 PM
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
    Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5
    FEB 13, 2019 | 10:30 AM
    Qualitative, Biased, Personal and Speculative Remarks on Digitization, Digitalization & Digital Transformation
    Qualitative, Biased, Personal and Speculative Remarks on Digitization,...
    A collection of opinions, questions and other assorted thoughts about the intersection of these developing technologies and preclinical studies primarily focused on the early discovery (as op...
    Speaker: Sean Maguire, VMD, MS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    4
    FEB 13, 2019 | 10:30 AM
    Accurate Clinical Concentration-Response Predictions for Cardiac Arrhythmias Using a Population-Based in Vitro/In Silico Model
    Accurate Clinical Concentration-Response Predictions for Cardiac...
    Xenobiotic-induced cardiotoxicity is a major concern for both pharmaceuticals and chemicals in the marketplace. For drugs, "Thorough QT/corrected QT (QTc)" (TQT) studies are corners...
    Speaker: Weihsueh Chiu, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5 1
     
     
  • FEB 13, 2019 | 9:00 AM
    Making Data Fly in Formation
    Making Data Fly in Formation
    In biomedical research, data should be treated as first-class corporate assets--they were expensive to create, they are expensive to maintain, and they have future business value. The petabyt...
    Speaker: Chuck Donnelly , Julie Morrison
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    1
    FEB 13, 2019 | 7:30 AM
    Keynote Presentation: Modernizing Drug Development Through Digital Transformation and Non-Traditional Models
    Keynote Presentation: Modernizing Drug Development Through Digital...
    Digitalization has transformed virtually every industry, but it has been slow to gain traction within the preclinical phase of the drug development journey. Recent advances in digital vivariu...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    6
    DEC 10, 2018 | 10:00 PM
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
    DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
    Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
    Sponsored By: Revvity
    4 1
    DEC 06, 2018 | 8:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:  December 6, 2018TIME:   11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    2
    DEC 06, 2018 | 1:00 AM
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
    Using Micro-CT Imaging for the Phenotyping and Analysis of Bone...
    DATE:    December 6, 2018TIME:    10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
    Speaker: Rob van 't Hof, BSc, MSc, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    8
     
     
  • OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    SEP 20, 2018 | 8:00 AM
    Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
    Cardiovascular Disease: Applying MRI to study atherosclerosis,...
     DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
    Speaker: Claudia Calcagno Mani, MD, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    10
    SEP 20, 2018 | 1:00 AM
    Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
    Cardiovascular Disease: Applying MRI to study atherosclerosis,...
    DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
    Speaker: Claudia Calcagno Mani, MD, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    6 1
    JUN 26, 2018 | 9:00 AM
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
    Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
    Speaker: Laura Schaevitz, PhD
    Sponsored By: Vium
    6
    JUN 07, 2018 | 7:00 AM
    How microCT Can Provide Insight into Dynamic Disease Processes
    How microCT Can Provide Insight into Dynamic Disease Processes
    DATE: June 7, 2018TIME: 07:00AM PDT, 4:00PM CESTIn this webinar, Prof. Greetje Vande Velde will give an overview of her work, which involves lung and brain infections.  Dr Vande Ve...
    Speaker: Greetje Vande Velde
    Sponsored By: Bruker Microbiology & Diagnostics
    4 1
     
     
  • MAY 30, 2018 | 10:30 AM
    Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
    Inhibitors of NSD2 Discovered by High-Throughput Screening with...
    NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
    Speaker: Nathan Coussens, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    1
    APR 06, 2018 | 9:00 AM
    Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
    Multiplex Immunofluorescence Profiling of Tumor Biopsies Using...
    DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
    Speaker: Helen Snyder, PhD , Marie-Louise Loupart, PhD
    Sponsored By: Leica Biosystems
    8
    FEB 08, 2018 | 1:30 PM
    Applications of Preclinical Translational Imaging Technologies for Improved Modeling and Decision Making
    Applications of Preclinical Translational Imaging Technologies...
    Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
    Speaker: Paul Makidon, DVM, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
    3
    FEB 08, 2018 | 7:30 AM
    Modernization of Animal Studies
    Modernization of Animal Studies
    There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
    Speaker: Natalie Bratcher , Sean Maguire, VMD, MS, DACLAM , Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
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