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    Sequencing

    Sequencing: is the process of determining the nucleic acid sequence - the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine.

    Webinars

    • FEB 05, 2014 | 9:00 AM
      Going Back to Nature: The Benefits of Wood Enrichment
      Going Back to Nature: The Benefits of Wood Enrichment
      Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
      Speaker: Karen Froberg-Fejko, LATg, VMD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 9:00 AM
      C.E. CREDITS
      Certifying competence
      Certifying competence
      Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
      Speaker: Bryan R Howard, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      42
      FEB 05, 2014 | 8:00 AM
      The 8th Edition of the Guide: An Environmental Impact
      The 8th Edition of the Guide: An Environmental Impact
      The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
      Speaker: John Bradfield, PhD, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 05, 2014 | 7:00 AM
      C.E. CREDITS
      Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs
      Simplifying Rodent Surgery... Tips for improving technique without...
      Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      47
      FEB 05, 2014 | 6:00 AM
      C.E. CREDITS
      Bedding vs. Thermoregulation
      Bedding vs. Thermoregulation
      This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
      Speaker: Andrea Gay
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      28 1
      NOV 20, 2013 | 11:00 AM
      Tools to accelerate biomarker screening for CDx
      Tools to accelerate biomarker screening for CDx
      ...
      Speaker: Dan Rhodes, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      199
      NOV 20, 2013 | 10:00 AM
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
      2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
      Speaker: Nicole Littmann
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      50
      NOV 08, 2013 | 12:00 PM
      Childhood cancer with various genomic assay including whole genome sequencing
      Childhood cancer with various genomic assay including whole genome...
      The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
      Speaker: Jaime Guidry Auvil, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      4
      OCT 17, 2013 | 1:00 PM
      C.E. CREDITS
      Transcriptome sequencing in translational oncology research
      Transcriptome sequencing in translational oncology research
      Invading cancer cells leave the tumor to form distant metastases and are ultimately responsible for 90% of deaths in cancer. Reducing the ability of cancer cells to invade and metastasize cou...
      Speaker: Milan Radovich, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      64
      OCT 17, 2013 | 9:00 AM
      Using DNASTAR Software to Identify Cancer Variations in Targeted Resequencing Data
      Using DNASTAR Software to Identify Cancer Variations in Targeted...
      DNASTAR offers an integrated suite of software for assembling and analyzing data from all major next-generation sequencing platforms. The software supports a variety of reference guided and d...
      Speaker: Matthew Keyser, MS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      48
      OCT 17, 2013 | 8:00 AM
      C.E. CREDITS
      Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
      Next-generation Cancer Care in the Age of Genomics, Precision...
      Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
      Speaker: C Jimmy Lin, MD, PhD, MHS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      52
      OCT 17, 2013 | 7:00 AM
      Noninvasive Cancer Genomics
      Noninvasive Cancer Genomics
      Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
      Speaker: Charles Cantor, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      50
      OCT 17, 2013 | 7:00 AM
      Advancing Translational Cancer Research through Automated RNASeq Sample Preparation from Archival FFPE Tissue Specimens
      Advancing Translational Cancer Research through Automated RNASeq...
      RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...
      Speaker: Michaela Bowden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      98
      OCT 17, 2013 | 6:00 AM
      A Bioinformatics Approach to Clinical Sequencing
      A Bioinformatics Approach to Clinical Sequencing
      The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
      Speaker: Dan Rhodes, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 3:00 PM
      C.E. CREDITS
      The roles of Ack family kinases in Drosophila development
      The roles of Ack family kinases in Drosophila development
      Deregulation of ACK1, a non-receptor tyrosine kinase originally identified by its ability to bind to GTP-bound Cdc42 (hence the name: activated Cdc42-associated kinase)(Manser et al., 1993),...
      Speaker: Henry Chang, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      42
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      68
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
      Resistance to AR Signaling Inhibitors in Castration Resistant...
      While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
      Speaker: Elahe A Mostaghel, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 11:00 AM
      C.E. CREDITS
      Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
      Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
      Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
      Speaker: Ross L. Cagan, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      78
      OCT 16, 2013 | 11:00 AM
      SuperSelective PCR Primers for the Detection of Rare Mutant Cancer Cells in Clinical Samples Containing Abundant Normal Cells
      SuperSelective PCR Primers for the Detection of Rare Mutant Cancer...
      "SuperSelective" primers, by virtue of their unique design, enable only a few molecules of a mutant sequence to generate amplicons in conventional, real-time PCR assays without interference...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      90
      OCT 16, 2013 | 10:00 AM
      C.E. CREDITS
      Keynote: Is Personalized (Molecularly-Based) Medicine our Best Hope to Finally Defeat Cancer?
      Keynote: Is Personalized (Molecularly-Based) Medicine our Best...
      The current paradigm of detecting established cancer (often too late) and treating routinely with cytotoxic drugs is beginning to change. Advanced technologies such as whole genome sequencin...
      Speaker: Anna Barker, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      37
      OCT 16, 2013 | 9:00 AM
      C.E. CREDITS
      Keynote: Breast Cancer Genomics and Genetics
      Keynote: Breast Cancer Genomics and Genetics
      It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
      Speaker: Charles M. Perou, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      132
      OCT 16, 2013 | 7:00 AM
      C.E. CREDITS
      Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
      Prognostic, predictive, and surrogate biomarkers in men with castration...
      With the rapid rise in the number of therapeutic options for men with castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision-making, emphasizing the nee...
      Speaker: Andrew Armstrong, MD ScM FACP
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      96
      OCT 16, 2013 | 6:00 AM
      Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium development of a tool for clinical research applications
      Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium...
      The knowledge of molecular alterations involved in colon carcinoma (CRC) and non-small-cell lung carcinoma (NSCLC) has significantly increased in the past few years. Molecular subgroups of t...
      Speaker: Nicola Normanno, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      102
      AUG 22, 2013 | 4:00 PM
      C.E. CREDITS
      Complexity of Mammalian Transcription
      Complexity of Mammalian Transcription
      The next generation sequencing technologies are profoundly influencing our way to study biology. We have previously developed cap-analysis gene expression (CAGE) to simultaneously mRNA/noncod...
      Speaker: Piero Carninci, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      50
    FEB 05, 2014 | 9:00 AM
    Going Back to Nature: The Benefits of Wood Enrichment
    Going Back to Nature: The Benefits of Wood Enrichment
    Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
    Speaker: Karen Froberg-Fejko, LATg, VMD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 9:00 AM
    C.E. CREDITS
    Certifying competence
    Certifying competence
    Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
    Speaker: Bryan R Howard, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    42
    FEB 05, 2014 | 8:00 AM
    The 8th Edition of the Guide: An Environmental Impact
    The 8th Edition of the Guide: An Environmental Impact
    The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
    Speaker: John Bradfield, PhD, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 05, 2014 | 7:00 AM
    C.E. CREDITS
    Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs
    Simplifying Rodent Surgery... Tips for improving technique without...
    Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    47
    FEB 05, 2014 | 6:00 AM
    C.E. CREDITS
    Bedding vs. Thermoregulation
    Bedding vs. Thermoregulation
    This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
    Speaker: Andrea Gay
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    28 1
     
     
  • NOV 20, 2013 | 11:00 AM
    Tools to accelerate biomarker screening for CDx
    Tools to accelerate biomarker screening for CDx
    ...
    Speaker: Dan Rhodes, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    199
    NOV 20, 2013 | 10:00 AM
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
    2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
    Speaker: Nicole Littmann
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    50
    NOV 08, 2013 | 12:00 PM
    Childhood cancer with various genomic assay including whole genome sequencing
    Childhood cancer with various genomic assay including whole genome...
    The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
    Speaker: Jaime Guidry Auvil, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    4
    OCT 17, 2013 | 1:00 PM
    C.E. CREDITS
    Transcriptome sequencing in translational oncology research
    Transcriptome sequencing in translational oncology research
    Invading cancer cells leave the tumor to form distant metastases and are ultimately responsible for 90% of deaths in cancer. Reducing the ability of cancer cells to invade and metastasize cou...
    Speaker: Milan Radovich, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    64
    OCT 17, 2013 | 9:00 AM
    Using DNASTAR Software to Identify Cancer Variations in Targeted Resequencing Data
    Using DNASTAR Software to Identify Cancer Variations in Targeted...
    DNASTAR offers an integrated suite of software for assembling and analyzing data from all major next-generation sequencing platforms. The software supports a variety of reference guided and d...
    Speaker: Matthew Keyser, MS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    48
     
     
  • OCT 17, 2013 | 8:00 AM
    C.E. CREDITS
    Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
    Next-generation Cancer Care in the Age of Genomics, Precision...
    Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
    Speaker: C Jimmy Lin, MD, PhD, MHS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    52
    OCT 17, 2013 | 7:00 AM
    Noninvasive Cancer Genomics
    Noninvasive Cancer Genomics
    Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
    Speaker: Charles Cantor, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    50
    OCT 17, 2013 | 7:00 AM
    Advancing Translational Cancer Research through Automated RNASeq Sample Preparation from Archival FFPE Tissue Specimens
    Advancing Translational Cancer Research through Automated RNASeq...
    RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...
    Speaker: Michaela Bowden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    98
    OCT 17, 2013 | 6:00 AM
    A Bioinformatics Approach to Clinical Sequencing
    A Bioinformatics Approach to Clinical Sequencing
    The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
    Speaker: Dan Rhodes, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    OCT 16, 2013 | 3:00 PM
    C.E. CREDITS
    The roles of Ack family kinases in Drosophila development
    The roles of Ack family kinases in Drosophila development
    Deregulation of ACK1, a non-receptor tyrosine kinase originally identified by its ability to bind to GTP-bound Cdc42 (hence the name: activated Cdc42-associated kinase)(Manser et al., 1993),...
    Speaker: Henry Chang, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    42
     
     
  • OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    68
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
    Resistance to AR Signaling Inhibitors in Castration Resistant...
    While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
    Speaker: Elahe A Mostaghel, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    OCT 16, 2013 | 11:00 AM
    C.E. CREDITS
    Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
    Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
    Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
    Speaker: Ross L. Cagan, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    78
    OCT 16, 2013 | 11:00 AM
    SuperSelective PCR Primers for the Detection of Rare Mutant Cancer Cells in Clinical Samples Containing Abundant Normal Cells
    SuperSelective PCR Primers for the Detection of Rare Mutant Cancer...
    "SuperSelective" primers, by virtue of their unique design, enable only a few molecules of a mutant sequence to generate amplicons in conventional, real-time PCR assays without interference...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    90
    OCT 16, 2013 | 10:00 AM
    C.E. CREDITS
    Keynote: Is Personalized (Molecularly-Based) Medicine our Best Hope to Finally Defeat Cancer?
    Keynote: Is Personalized (Molecularly-Based) Medicine our Best...
    The current paradigm of detecting established cancer (often too late) and treating routinely with cytotoxic drugs is beginning to change. Advanced technologies such as whole genome sequencin...
    Speaker: Anna Barker, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    37
     
     
  • OCT 16, 2013 | 9:00 AM
    C.E. CREDITS
    Keynote: Breast Cancer Genomics and Genetics
    Keynote: Breast Cancer Genomics and Genetics
    It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
    Speaker: Charles M. Perou, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    132
    OCT 16, 2013 | 7:00 AM
    C.E. CREDITS
    Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
    Prognostic, predictive, and surrogate biomarkers in men with castration...
    With the rapid rise in the number of therapeutic options for men with castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision-making, emphasizing the nee...
    Speaker: Andrew Armstrong, MD ScM FACP
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    96
    OCT 16, 2013 | 6:00 AM
    Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium development of a tool for clinical research applications
    Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium...
    The knowledge of molecular alterations involved in colon carcinoma (CRC) and non-small-cell lung carcinoma (NSCLC) has significantly increased in the past few years. Molecular subgroups of t...
    Speaker: Nicola Normanno, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    102
    AUG 22, 2013 | 4:00 PM
    C.E. CREDITS
    Complexity of Mammalian Transcription
    Complexity of Mammalian Transcription
    The next generation sequencing technologies are profoundly influencing our way to study biology. We have previously developed cap-analysis gene expression (CAGE) to simultaneously mRNA/noncod...
    Speaker: Piero Carninci, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    50
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