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    Small Molecule

    Small Molecule: Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight organic compound that may regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.

    Webinars

    • SEP 22, 2021 | 12:00 PM
      Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC® ONIX2 Microfluidic Platform
      Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC®...
      While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
      Speaker: Jun Park, PhD
      Presented at: Cell Biology Virtual Event Series 2021
      Sponsored By: MilliporeSigma
      0
      SEP 14, 2021 | 7:00 AM
      What prevents you from increasing your PCR productivity?
      What prevents you from increasing your PCR productivity?
      Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
      Speaker: Arora Phang, PhD
      Sponsored By: Eppendorf
      24 1
      AUG 25, 2021 | 10:30 AM
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
      Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
      Speaker: Jason D. Hinman, PhD, MD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: Luminex
      2
      AUG 25, 2021 | 7:30 AM
      Keynote Presentation: Development of Pharmacological Chaperones Targeting the Intrinsically Disordered State of Misfolding Proteins in Neurodegenerative Diseases
      Keynote Presentation: Development of Pharmacological Chaperones...
      The misfolding of intrinsically disordered proteins (IDPs) such as tau and α-synuclein (αSyn) has been associated with the on-set and progression of Alzheimer’s (AD) and Pa...
      Speaker: Gergely Tóth, PhD, MBA
      Presented at: Neuroscience Virtual Event Series 2021
      6
      AUG 25, 2021 | 12:00 AM
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
      Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
      Speaker: Andrii Domanskyi, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      5
      AUG 25, 2021 | 12:00 AM
      A Novel Mouse Model of Ataxia Telangiectasia for Testing Small Molecule Readthrough (SMRT) Compounds
      A Novel Mouse Model of Ataxia Telangiectasia for Testing Small...
      Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
      JUL 20, 2021 | 10:00 AM
      Drug Stability Testing 101: How to Ensure Your Pharmaceutical Testing Can Handle the Heat
      Drug Stability Testing 101: How to Ensure Your Pharmaceutical...
      Date: July 20, 2021 Time: 10:00am PDT From raw material identification to finished and packaged pharmaceutical products, stability testing is a critical step for both research and developmen...
      Speaker: Felisha Pierre-Louis, MBA , Bernie Schwartz, BSBA
      Sponsored By: Thermo Fisher Scientific
      9 2
      JUN 15, 2021 | 10:00 AM
      Single cell & label free binding affinity: applications with Genentech
      Single cell & label free binding affinity: applications with Genentech
      Date: June 15, 2021 Time: 10:00am (PDT), 1:00pm (EDT) SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time binding affinity and kinetics of...
      Speaker: Elaine Mai, MS , Dr. Shijie Wu
      Sponsored By: Biosensing Instrument
      3
      JUN 10, 2021 | 7:00 AM
      Simplify complex genetic diseases by quantifying structural and copy number variants
      Simplify complex genetic diseases by quantifying structural and...
      Date: June 10, 2021 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Discover how to categorize small-to-large genetic modifications using molecular combing. Our Proprietary Genome Morse Cod...
      Speaker: Mario Avarello, MSc
      Sponsored By: Genomic Vision
      8 1
      JUN 09, 2021 | 7:00 AM
      Preventing cell misidentification in your daily lab routine
      Preventing cell misidentification in your daily lab routine
      Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
      Speaker: Gabriela Saldanha , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      40 3
      JUN 02, 2021 | 7:00 AM
      At the edge of genomics: Sequencing single viral particles, One at a time.
      At the edge of genomics: Sequencing single viral particles, One...
      DATE: June 02, 2021 TIME: 7:00am PDT In this talk we will present how we have optimized single-cell technologies to sort single viral particles by advanced flow cytometry and whole genome am...
      Speaker: Dr. Manuel Martinez-Garcia
      Sponsored By: GenScript
      17 1
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      APR 22, 2021 | 6:00 AM
      Panel Presentation: Powering the precision in "precision medicine" - The role of curated data, databases and knowledge: Does a gold standard exist?
      Panel Presentation: Powering the precision in "precision medicine"...
      As NGS panels grow, test interpretation becomes more complex and time-consuming / With the explosion of NGS data, the need for consolidated databases with reliable and transparent curation a...
      Speaker: Dominic John , Simon Forbes, PhD , Shawn Bauer , Lisa Barrow-Laing
      Presented at: Genetics Week Virtual Event Series 2021
      Sponsored By: QIAGEN
      2
      APR 14, 2021 | 3:00 PM
      Quick and Easy Sequencing of SARS-CoV-2 to Identify Variants of Concern
      Quick and Easy Sequencing of SARS-CoV-2 to Identify Variants of...
      Dr. Jordan RoseFigura from Swift Biosciences will present on the technology created to enable this research that covers 99.7 % of the SARS-CoV-2 genome from limited viral titers. Including a...
      Speaker: Jordan RoseFigura, PhD
      Presented at: Coronavirus Series
      Sponsored By: Swift Biosciences
      4
      MAR 17, 2021 | 8:00 AM
      Advanced enzymes to facilitate SARS-CoV-2 research
      Advanced enzymes to facilitate SARS-CoV-2 research
      Date: March 17, 2021 Time: 08:00am (PST) Research focused on SARS-CoV-2 has become a primary focus in genomic and molecular biology fields. With a constantly changing field with new methods...
      Speaker: Li Lavelle
      Sponsored By: Thermo Fisher Scientific
      24 1
      FEB 24, 2021 | 3:00 PM
      PROTACs: A Chemistry Journey of Protein Degraders
      PROTACs: A Chemistry Journey of Protein Degraders
      This talk reviews the advances in the field of Proteolysis Targeting Chimeras (PROTACs). It is divided to five topics: (1) Ligand-induced Target Protein Destabilization; (2) Small-Molecule L...
      Speaker: Jie Jack Li, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      Sponsored By: ChemPartner
      2
      FEB 24, 2021 | 1:30 PM
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
      Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      1
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      FEB 24, 2021 | 9:00 AM
      Keynote Panel Presentation: Biomarker assays - bioanalytical meets CLIA
      Keynote Panel Presentation: Biomarker assays - bioanalytical meets...
      Reliable diagnostic, prognostic, predictive, pharmacodynamic, and pharmacokinetic biomarkers are critical to assure correct patient selection, drug dosing, and monitoring. Being able to iden...
      Speaker: Andrew Roche, PhD , Roger Hayes, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      1
      FEB 24, 2021 | 12:00 AM
      Evolution of a Platform-Based Non-Clinical Safety Assessment Approach for Vaccines
      Evolution of a Platform-Based Non-Clinical Safety Assessment Approach...
      Platform based therapeutics and vaccines offer a unique opportunity to simplify and streamline the drug development process. Moderna has taken the approach of harnessing the power of mRNA as...
      Speaker: Joseph J. Senn, PhD, DABT
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      2
      JAN 12, 2021 | 8:00 AM
      Storage and Logistics of Vaccines at Ultra Low Temperatures
      Storage and Logistics of Vaccines at Ultra Low Temperatures
      DATE: January 12, 2021 TIME: 8:00 am PST, 11:00 am EST, 5:00pm CET Transferring a biologic candidate from the research and development phase to commercial production usually requires increas...
      Speaker: Dr. Alex Esmon
      Sponsored By: Thermo Fisher Scientific
      9
      DEC 09, 2020 | 7:00 AM
      Characterization of RNA therapeutics from small to large
      Characterization of RNA therapeutics from small to large
      Date: December 9, 2020 Time: 7:00am (PST), 10:00am (EST) In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messen...
      Speaker: Stephen Lock, PhD
      Sponsored By: SCIEX
      5
      DEC 08, 2020 | 7:00 AM
      Best TLC & HPTLC practices in pharmaceutical separations
      Best TLC & HPTLC practices in pharmaceutical separations
      Thin-Layer Chromatography (TLC) and High-Performance Thin-Layer Chromatography (HPTLC) are convenient, fast, and efficient separation techniques for analytical methods without demanding comp...
      Speaker: Monika Bäeumle , Michaela Oberle , Melanie Broszat
      Sponsored By: MilliporeSigma
      14 1
      DEC 02, 2020 | 8:00 AM
      Optimize your bioprocess - From shaker to bioreactor
      Optimize your bioprocess - From shaker to bioreactor
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      Speaker: Ines Hartmann , David Solbach
      Sponsored By: Eppendorf
      11
    SEP 22, 2021 | 12:00 PM
    Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC® ONIX2 Microfluidic Platform
    Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC®...
    While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
    Speaker: Jun Park, PhD
    Presented at: Cell Biology Virtual Event Series 2021
    Sponsored By: MilliporeSigma
    0
    SEP 14, 2021 | 7:00 AM
    What prevents you from increasing your PCR productivity?
    What prevents you from increasing your PCR productivity?
    Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
    Speaker: Arora Phang, PhD
    Sponsored By: Eppendorf
    24 1
    AUG 25, 2021 | 10:30 AM
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
    Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
    Speaker: Jason D. Hinman, PhD, MD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: Luminex
    2
    AUG 25, 2021 | 7:30 AM
    Keynote Presentation: Development of Pharmacological Chaperones Targeting the Intrinsically Disordered State of Misfolding Proteins in Neurodegenerative Diseases
    Keynote Presentation: Development of Pharmacological Chaperones...
    The misfolding of intrinsically disordered proteins (IDPs) such as tau and α-synuclein (αSyn) has been associated with the on-set and progression of Alzheimer’s (AD) and Pa...
    Speaker: Gergely Tóth, PhD, MBA
    Presented at: Neuroscience Virtual Event Series 2021
    6
    AUG 25, 2021 | 12:00 AM
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
    Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
    Speaker: Andrii Domanskyi, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    5
     
     
  • AUG 25, 2021 | 12:00 AM
    A Novel Mouse Model of Ataxia Telangiectasia for Testing Small Molecule Readthrough (SMRT) Compounds
    A Novel Mouse Model of Ataxia Telangiectasia for Testing Small...
    Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
    JUL 20, 2021 | 10:00 AM
    Drug Stability Testing 101: How to Ensure Your Pharmaceutical Testing Can Handle the Heat
    Drug Stability Testing 101: How to Ensure Your Pharmaceutical...
    Date: July 20, 2021 Time: 10:00am PDT From raw material identification to finished and packaged pharmaceutical products, stability testing is a critical step for both research and developmen...
    Speaker: Felisha Pierre-Louis, MBA , Bernie Schwartz, BSBA
    Sponsored By: Thermo Fisher Scientific
    9 2
    JUN 15, 2021 | 10:00 AM
    Single cell & label free binding affinity: applications with Genentech
    Single cell & label free binding affinity: applications with Genentech
    Date: June 15, 2021 Time: 10:00am (PDT), 1:00pm (EDT) SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time binding affinity and kinetics of...
    Speaker: Elaine Mai, MS , Dr. Shijie Wu
    Sponsored By: Biosensing Instrument
    3
    JUN 10, 2021 | 7:00 AM
    Simplify complex genetic diseases by quantifying structural and copy number variants
    Simplify complex genetic diseases by quantifying structural and...
    Date: June 10, 2021 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Discover how to categorize small-to-large genetic modifications using molecular combing. Our Proprietary Genome Morse Cod...
    Speaker: Mario Avarello, MSc
    Sponsored By: Genomic Vision
    8 1
    JUN 09, 2021 | 7:00 AM
    Preventing cell misidentification in your daily lab routine
    Preventing cell misidentification in your daily lab routine
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    Speaker: Gabriela Saldanha , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    40 3
     
     
  • JUN 02, 2021 | 7:00 AM
    At the edge of genomics: Sequencing single viral particles, One at a time.
    At the edge of genomics: Sequencing single viral particles, One...
    DATE: June 02, 2021 TIME: 7:00am PDT In this talk we will present how we have optimized single-cell technologies to sort single viral particles by advanced flow cytometry and whole genome am...
    Speaker: Dr. Manuel Martinez-Garcia
    Sponsored By: GenScript
    17 1
    MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    APR 22, 2021 | 6:00 AM
    Panel Presentation: Powering the precision in "precision medicine" - The role of curated data, databases and knowledge: Does a gold standard exist?
    Panel Presentation: Powering the precision in "precision medicine"...
    As NGS panels grow, test interpretation becomes more complex and time-consuming / With the explosion of NGS data, the need for consolidated databases with reliable and transparent curation a...
    Speaker: Dominic John , Simon Forbes, PhD , Shawn Bauer , Lisa Barrow-Laing
    Presented at: Genetics Week Virtual Event Series 2021
    Sponsored By: QIAGEN
    2
    APR 14, 2021 | 3:00 PM
    Quick and Easy Sequencing of SARS-CoV-2 to Identify Variants of Concern
    Quick and Easy Sequencing of SARS-CoV-2 to Identify Variants of...
    Dr. Jordan RoseFigura from Swift Biosciences will present on the technology created to enable this research that covers 99.7 % of the SARS-CoV-2 genome from limited viral titers. Including a...
    Speaker: Jordan RoseFigura, PhD
    Presented at: Coronavirus Series
    Sponsored By: Swift Biosciences
    4
    MAR 17, 2021 | 8:00 AM
    Advanced enzymes to facilitate SARS-CoV-2 research
    Advanced enzymes to facilitate SARS-CoV-2 research
    Date: March 17, 2021 Time: 08:00am (PST) Research focused on SARS-CoV-2 has become a primary focus in genomic and molecular biology fields. With a constantly changing field with new methods...
    Speaker: Li Lavelle
    Sponsored By: Thermo Fisher Scientific
    24 1
     
     
  • FEB 24, 2021 | 3:00 PM
    PROTACs: A Chemistry Journey of Protein Degraders
    PROTACs: A Chemistry Journey of Protein Degraders
    This talk reviews the advances in the field of Proteolysis Targeting Chimeras (PROTACs). It is divided to five topics: (1) Ligand-induced Target Protein Destabilization; (2) Small-Molecule L...
    Speaker: Jie Jack Li, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    Sponsored By: ChemPartner
    2
    FEB 24, 2021 | 1:30 PM
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
    Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    1
    FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
    FEB 24, 2021 | 9:00 AM
    Keynote Panel Presentation: Biomarker assays - bioanalytical meets CLIA
    Keynote Panel Presentation: Biomarker assays - bioanalytical meets...
    Reliable diagnostic, prognostic, predictive, pharmacodynamic, and pharmacokinetic biomarkers are critical to assure correct patient selection, drug dosing, and monitoring. Being able to iden...
    Speaker: Andrew Roche, PhD , Roger Hayes, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    1
    FEB 24, 2021 | 12:00 AM
    Evolution of a Platform-Based Non-Clinical Safety Assessment Approach for Vaccines
    Evolution of a Platform-Based Non-Clinical Safety Assessment Approach...
    Platform based therapeutics and vaccines offer a unique opportunity to simplify and streamline the drug development process. Moderna has taken the approach of harnessing the power of mRNA as...
    Speaker: Joseph J. Senn, PhD, DABT
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    2
     
     
  • JAN 12, 2021 | 8:00 AM
    Storage and Logistics of Vaccines at Ultra Low Temperatures
    Storage and Logistics of Vaccines at Ultra Low Temperatures
    DATE: January 12, 2021 TIME: 8:00 am PST, 11:00 am EST, 5:00pm CET Transferring a biologic candidate from the research and development phase to commercial production usually requires increas...
    Speaker: Dr. Alex Esmon
    Sponsored By: Thermo Fisher Scientific
    9
    DEC 09, 2020 | 7:00 AM
    Characterization of RNA therapeutics from small to large
    Characterization of RNA therapeutics from small to large
    Date: December 9, 2020 Time: 7:00am (PST), 10:00am (EST) In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messen...
    Speaker: Stephen Lock, PhD
    Sponsored By: SCIEX
    5
    DEC 08, 2020 | 7:00 AM
    Best TLC & HPTLC practices in pharmaceutical separations
    Best TLC & HPTLC practices in pharmaceutical separations
    Thin-Layer Chromatography (TLC) and High-Performance Thin-Layer Chromatography (HPTLC) are convenient, fast, and efficient separation techniques for analytical methods without demanding comp...
    Speaker: Monika Bäeumle , Michaela Oberle , Melanie Broszat
    Sponsored By: MilliporeSigma
    14 1
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
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