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    Stem Cell Disease Modeling

    Stem cell disease modeling is technology that uses cell culture and imaging techniques to develop new therapeutic approaches to treat disease. An example of stem cell disease models include induced pluripotent stem cells (iPSCs).

    Webinars

    • MAR 07, 2019 | 7:00 AM
      Pluripotent stem cells:  How to raise the quality of your PSC culture
      Pluripotent stem cells: How to raise the quality of your PSC...
      DATE:    March 7, 2019TIME:    4:00pm CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      4
      MAR 06, 2019 | 11:00 PM
      Pluripotent stem cells: How to raise the quality of your PSC culture
      Pluripotent stem cells: How to raise the quality of your PSC culture
      DATE:    March 7, 2019TIME:    8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      5
      FEB 27, 2019 | 1:30 PM
      Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
      Advances in Three-Dimensional Cell Culture in Drug Research and...
      Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
      Speaker: Richard Eglen, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 8:00 AM
      Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
      Prepare for success: GMP cell banks as part of a staged, standardized,...
      DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
      Speaker: Benjamin Fryer
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
      FEB 20, 2019 | 9:00 AM
      Choosing the best system to answer your question - What question are you looking to answer?
      Choosing the best system to answer your question - What question...
      DATE:  February 20, 2019TIME:  9:00am PST  ...
      Speaker: David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      15 1
      JAN 31, 2019 | 1:30 PM
      Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
      Standardization of Cell Viability Assays in Primary Cells as a...
      Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
      Speaker: Simon Kaja, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      2
      DEC 06, 2018 | 9:00 AM
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      DEC 05, 2018 | 8:00 PM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      5 3
      DEC 05, 2018 | 7:00 AM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      DEC 04, 2018 | 7:00 AM
      Pluripotent stem cells:  How to raise the quality of your PSC culture
      Pluripotent stem cells: How to raise the quality of your PSC...
      DATE:    December 4, 2018TIME:    4:00pm CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      5
      DEC 03, 2018 | 11:00 PM
      Pluripotent stem cells: How to raise the quality of your PSC culture
      Pluripotent stem cells: How to raise the quality of your PSC culture
      DATE:    December 4, 2018TIME:    8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      5
      NOV 15, 2018 | 12:00 PM
      Using human stem cells to model neocortical gyration phenotypes
      Using human stem cells to model neocortical gyration phenotypes
      Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
      Speaker: Ashleigh Schaffer
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      6 1
      NOV 15, 2018 | 11:00 AM
      LIVE TRAINING: Differentiating neurons
      LIVE TRAINING: Differentiating neurons
      Generation of robust iPSC-derived neural stem cell cultures and neurons with shorter maturation times provide opportunities for quick and reliable generation of neuronal in vitro models. This...
      Speaker: Jordan Dizon
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      7
      NOV 15, 2018 | 10:00 AM
      Applications of Brain-Model Technology
      Applications of Brain-Model Technology
      The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thou...
      Speaker: Alysson Muotri
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      4
      NOV 15, 2018 | 8:00 AM
      Precise Gene Editing of Human Pluripotent Stem Cells
      Precise Gene Editing of Human Pluripotent Stem Cells
      CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
      Speaker: Kris Saha
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      11
      NOV 15, 2018 | 7:00 AM
      Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
      Use of stem-cell derived endothelial cells for disease relevant...
      The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
      Speaker: Filip Roudnicky
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      8
      NOV 15, 2018 | 4:00 AM
      Generation and application of 3D-organoid cell culture models using human induced pluripotent stem cells (iPSCs) for drug discovery
      Generation and application of 3D-organoid cell culture models...
      Development of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...
      Speaker: Ryan Hicks
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      10 2
      NOV 14, 2018 | 3:00 PM
      Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
      Modeling Inflammation and Fibrosis in Humans with PSC-derived...
      Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
      Speaker: Takanori Takebe
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      8
      NOV 02, 2018 | 12:00 AM
      A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
      A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
      Despite exciting recent developments in neuroscience, identifying novel, truly effective treatments for patients with neurological and psychiatric conditions remains highly challenging. There...
      Speaker: Susana Alcantara
      Presented at: Dimension of Time: From Culture to Assay
      3
      OCT 25, 2018 | 8:00 AM
      Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
      Disease modeling and cancer therapy in stem cell-derived 3D organoid...
      DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
      Speaker: Devanjali Dutta, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
    MAR 07, 2019 | 7:00 AM
    Pluripotent stem cells:  How to raise the quality of your PSC culture
    Pluripotent stem cells: How to raise the quality of your PSC...
    DATE:    March 7, 2019TIME:    4:00pm CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    4
    MAR 06, 2019 | 11:00 PM
    Pluripotent stem cells: How to raise the quality of your PSC culture
    Pluripotent stem cells: How to raise the quality of your PSC culture
    DATE:    March 7, 2019TIME:    8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    5
    FEB 27, 2019 | 1:30 PM
    Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
    Advances in Three-Dimensional Cell Culture in Drug Research and...
    Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
    Speaker: Richard Eglen, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 8:00 AM
    Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
    Prepare for success: GMP cell banks as part of a staged, standardized,...
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    Speaker: Benjamin Fryer
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
    FEB 20, 2019 | 9:00 AM
    Choosing the best system to answer your question - What question are you looking to answer?
    Choosing the best system to answer your question - What question...
    DATE:  February 20, 2019TIME:  9:00am PST  ...
    Speaker: David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
    15 1
     
     
  • JAN 31, 2019 | 1:30 PM
    Standardization of Cell Viability Assays in Primary Cells as a Prerequisite for Novel Bioprocessing Applications
    Standardization of Cell Viability Assays in Primary Cells as a...
    Development of novel types of therapeutics require adaptation of traditional bioprocessing applications to include the use of primary cells, such as stem cells, fibroblasts, astrocytes and ne...
    Speaker: Simon Kaja, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    2
    DEC 06, 2018 | 9:00 AM
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    DEC 05, 2018 | 8:00 PM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    5 3
    DEC 05, 2018 | 7:00 AM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    DEC 04, 2018 | 7:00 AM
    Pluripotent stem cells:  How to raise the quality of your PSC culture
    Pluripotent stem cells: How to raise the quality of your PSC...
    DATE:    December 4, 2018TIME:    4:00pm CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    5
     
     
  • DEC 03, 2018 | 11:00 PM
    Pluripotent stem cells: How to raise the quality of your PSC culture
    Pluripotent stem cells: How to raise the quality of your PSC culture
    DATE:    December 4, 2018TIME:    8:00am CET PSCs represent an important tool in a wide range of applications, including basic research, disease...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    5
    NOV 15, 2018 | 12:00 PM
    Using human stem cells to model neocortical gyration phenotypes
    Using human stem cells to model neocortical gyration phenotypes
    Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
    Speaker: Ashleigh Schaffer
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    6 1
    NOV 15, 2018 | 11:00 AM
    LIVE TRAINING: Differentiating neurons
    LIVE TRAINING: Differentiating neurons
    Generation of robust iPSC-derived neural stem cell cultures and neurons with shorter maturation times provide opportunities for quick and reliable generation of neuronal in vitro models. This...
    Speaker: Jordan Dizon
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    7
    NOV 15, 2018 | 10:00 AM
    Applications of Brain-Model Technology
    Applications of Brain-Model Technology
    The complexity of the human brain, with thousands of neuronal types, permits the development of sophisticated behavioral repertoires, such as language, tool use, self-awareness, symbolic thou...
    Speaker: Alysson Muotri
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    4
    NOV 15, 2018 | 8:00 AM
    Precise Gene Editing of Human Pluripotent Stem Cells
    Precise Gene Editing of Human Pluripotent Stem Cells
    CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
    Speaker: Kris Saha
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    11
     
     
  • NOV 15, 2018 | 7:00 AM
    Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
    Use of stem-cell derived endothelial cells for disease relevant...
    The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
    Speaker: Filip Roudnicky
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    8
    NOV 15, 2018 | 4:00 AM
    Generation and application of 3D-organoid cell culture models using human induced pluripotent stem cells (iPSCs) for drug discovery
    Generation and application of 3D-organoid cell culture models...
    Development of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...
    Speaker: Ryan Hicks
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    10 2
    NOV 14, 2018 | 3:00 PM
    Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
    Modeling Inflammation and Fibrosis in Humans with PSC-derived...
    Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
    Speaker: Takanori Takebe
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    8
    NOV 02, 2018 | 12:00 AM
    A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
    A Neuroscientist's Guide to Live-Cell Analysis: Techniques & Benefits
    Despite exciting recent developments in neuroscience, identifying novel, truly effective treatments for patients with neurological and psychiatric conditions remains highly challenging. There...
    Speaker: Susana Alcantara
    Presented at: Dimension of Time: From Culture to Assay
    3
    OCT 25, 2018 | 8:00 AM
    Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
    Disease modeling and cancer therapy in stem cell-derived 3D organoid...
    DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
    Speaker: Devanjali Dutta, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
     
     
  • OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
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