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    Stem Cell Disease Modeling

    Stem cell disease modeling is technology that uses cell culture and imaging techniques to develop new therapeutic approaches to treat disease. An example of stem cell disease models include induced pluripotent stem cells (iPSCs).

    Webinars

    • OCT 03, 2018 | 12:00 PM
      Using CRISPR and Stem Cells to Treat Genetic Disease
      Using CRISPR and Stem Cells to Treat Genetic Disease
      Decoding human genetic disease allows us to develop models of the pathology that can be directly tested with gene correction or targeted drug therapy.  Dominant negative mutations are pa...
      Speaker: Bruce Conklin, MD
      Presented at: CRISPR Virtual Event Series 2018
      1
      OCT 03, 2018 | 10:30 AM
      Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
      Integrating Novel Advances in Gene Delivery and Genome Engineering...
      There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
      Speaker: David Schaffer, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      SEP 27, 2018 | 1:30 PM
      Cilia Abnormalities and Developmental Defects in Lowe Syndrome
      Cilia Abnormalities and Developmental Defects in Lowe Syndrome
      Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
      Speaker: R. Claudio Aguilar, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      2
      SEP 13, 2018 | 1:30 PM
      Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
      Mechanisms of Antimicrobial Bioconversion by Environmental and...
      The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
      Speaker: Terence Crofts, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 13, 2018 | 10:30 AM
      Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic Resistance
      Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic...
      Horizontal gene transfer (HGT) – or the non-genealogical transmission of DNA between organisms – is the dominant mode responsible for the spread of antibiotic resistance genes. Co...
      Speaker: Allison Lopatkin, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 13, 2018 | 10:30 AM
      Studying Environmental Sensing and Response in a Bacterial Plant Pathogen - Inside Out
      Studying Environmental Sensing and Response in a Bacterial Plant...
      The bacterium Pantoea stewartii subsp. stewartii causes Stewart’s wilt disease in corn and serves as a model for other xylem-dwelling phytopathogens. P. stewartii is transmitted to plan...
      Speaker: Ann Stevens, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 13, 2018 | 6:00 AM
      The Hurricane Microbiome Project: Environmental Exposures and Population Health
      The Hurricane Microbiome Project: Environmental Exposures and...
      The Alkek Center for Metagenomics and Microbiome Research (CMMR) at Baylor College of Medicine is pursuing numerous research and development efforts in the study of how the microbiome impacts...
      Speaker: Joseph Petrosino, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      1
      SEP 13, 2018 | 6:00 AM
      The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
      The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
      In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data...
      Speaker: Siobain Duffy, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      1
      SEP 12, 2018 | 10:30 AM
      Bacteria that Eat Electricity: Understanding Biocathodes Using Culture Independent Techniques
      Bacteria that Eat Electricity: Understanding Biocathodes Using...
      Some bacteria can use an electrode as an electron donor for respiration, generating an electrical current in the process. We are trying to understand a bacterial community that uses electrici...
      Speaker: Brian Eddie, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      2 1
      AUG 01, 2018 | 12:00 AM
      Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
      Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
      Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
      Speaker: Kapil Bharti
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      3
      JUL 19, 2018 | 9:00 AM
      Investigating the role of microRNAs in pancreatic cancer progression
      Investigating the role of microRNAs in pancreatic cancer progression
      DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
      Speaker: Silvia Ottaviani, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 5
      MAY 09, 2018 | 1:30 PM
      Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
      Next-Generation Sequencing to Understand the Function of miRNAs...
      There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
      Speaker: Ulrich Broeckel, MD , Amy Turner, BS
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      MAR 27, 2018 | 9:00 AM
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
      Speaker: Amanda Haas
      Sponsored By: Horizon Discovery
      23 15
      MAR 22, 2018 | 9:00 AM
      Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
      Differentiation sensitizes stem-like glioblastoma tumor-initiating...
      DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
      Speaker: Jasmine Hughes
      Sponsored By: Thermo Fisher Scientific/Gibco
      6 4
      MAR 15, 2018 | 10:30 AM
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
      Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
      The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
      Speaker: Jill Weimer, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      MAR 14, 2018 | 9:00 AM
      IPSC-Derived Human Neurons: Introduction and Application
      IPSC-Derived Human Neurons: Introduction and Application
      Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
      Speaker: Michael Hendrickson
      Presented at: Neuroscience Virtual Event Series 2018
      Sponsored By: BrainXell
      3 1
      MAR 01, 2018 | 12:00 AM
      Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
      Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
      The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
      Speaker: William Hendriks
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      2
      FEB 28, 2018 | 12:00 AM
      Improved Neuronal Performance with the Gibco B-27 Plus Culture System
      Improved Neuronal Performance with the Gibco B-27 Plus Culture...
      TBD...
      Speaker: David Kuninger, PhD
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      2
      JAN 25, 2018 | 8:00 AM
      WEBINAR:  Understanding Immunosuppressive Myeloid Cells and Immunotherapy using Proteome Profiler™ Arrays
      WEBINAR: Understanding Immunosuppressive Myeloid Cells and Immunotherapy...
      DATE: January 25, 2018TIME:  8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
      Speaker: Xin Lu, PhD
      Sponsored By: ACD - A Bio-Techne Brand
      6
      JAN 01, 2018 | 10:00 AM
      Disease modelling with human pluripotent stem cells: general principles and specific applications to obesity
      Disease modelling with human pluripotent stem cells: general principles...
      The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
      Speaker: Florian Merkle
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      2
      JAN 01, 2018 | 12:00 AM
      Human stem cells for modelling neurological disease and its therapeutic applications
      Human stem cells for modelling neurological disease and its therapeutic...
      My talk shall encompass how the stem cell research field has evolved from embryonic stem cells to adult stem cells and currently induced pluripotent stem cells with special reference to the f...
      Speaker: Rakhi Pal
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      2
      DEC 01, 2017 | 12:00 AM
      Beyond Automated iPSC reprogramming: applications for a fully automated cell culture system for pluripotent stem cell research
      Beyond Automated iPSC reprogramming: applications for a fully...
      The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
      Speaker: Daniel Paull
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
      1
      NOV 16, 2017 | 9:00 AM
      WEBINAR: Breaking Bad with 3D: The development of high throughput screening platforms to interrogate physiologically relevant models
      WEBINAR: Breaking Bad with 3D: The development of high throughput...
      DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
      Speaker: Madhu Nag, PhD
      Sponsored By: Revvity
      4
    OCT 03, 2018 | 12:00 PM
    Using CRISPR and Stem Cells to Treat Genetic Disease
    Using CRISPR and Stem Cells to Treat Genetic Disease
    Decoding human genetic disease allows us to develop models of the pathology that can be directly tested with gene correction or targeted drug therapy.  Dominant negative mutations are pa...
    Speaker: Bruce Conklin, MD
    Presented at: CRISPR Virtual Event Series 2018
    1
    OCT 03, 2018 | 10:30 AM
    Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
    Integrating Novel Advances in Gene Delivery and Genome Engineering...
    There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
    Speaker: David Schaffer, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    SEP 27, 2018 | 1:30 PM
    Cilia Abnormalities and Developmental Defects in Lowe Syndrome
    Cilia Abnormalities and Developmental Defects in Lowe Syndrome
    Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
    Speaker: R. Claudio Aguilar, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    2
    SEP 13, 2018 | 1:30 PM
    Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
    Mechanisms of Antimicrobial Bioconversion by Environmental and...
    The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
    Speaker: Terence Crofts, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 13, 2018 | 10:30 AM
    Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic Resistance
    Understanding and Inhibiting Horizontal Gene Transfer of Antibiotic...
    Horizontal gene transfer (HGT) – or the non-genealogical transmission of DNA between organisms – is the dominant mode responsible for the spread of antibiotic resistance genes. Co...
    Speaker: Allison Lopatkin, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
     
     
  • SEP 13, 2018 | 10:30 AM
    Studying Environmental Sensing and Response in a Bacterial Plant Pathogen - Inside Out
    Studying Environmental Sensing and Response in a Bacterial Plant...
    The bacterium Pantoea stewartii subsp. stewartii causes Stewart’s wilt disease in corn and serves as a model for other xylem-dwelling phytopathogens. P. stewartii is transmitted to plan...
    Speaker: Ann Stevens, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 13, 2018 | 6:00 AM
    The Hurricane Microbiome Project: Environmental Exposures and Population Health
    The Hurricane Microbiome Project: Environmental Exposures and...
    The Alkek Center for Metagenomics and Microbiome Research (CMMR) at Baylor College of Medicine is pursuing numerous research and development efforts in the study of how the microbiome impacts...
    Speaker: Joseph Petrosino, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    1
    SEP 13, 2018 | 6:00 AM
    The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
    The Evolution of Diverse, Ubiquitous CRESS DNA Viruses
    In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data...
    Speaker: Siobain Duffy, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    1
    SEP 12, 2018 | 10:30 AM
    Bacteria that Eat Electricity: Understanding Biocathodes Using Culture Independent Techniques
    Bacteria that Eat Electricity: Understanding Biocathodes Using...
    Some bacteria can use an electrode as an electron donor for respiration, generating an electrical current in the process. We are trying to understand a bacterial community that uses electrici...
    Speaker: Brian Eddie, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    2 1
    AUG 01, 2018 | 12:00 AM
    Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
    Autologous iPS cell therapy for Macular Degeneration: From bench-to-bedside
    Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
    Speaker: Kapil Bharti
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    3
     
     
  • JUL 19, 2018 | 9:00 AM
    Investigating the role of microRNAs in pancreatic cancer progression
    Investigating the role of microRNAs in pancreatic cancer progression
    DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
    Speaker: Silvia Ottaviani, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 5
    MAY 09, 2018 | 1:30 PM
    Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
    Next-Generation Sequencing to Understand the Function of miRNAs...
    There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
    Speaker: Ulrich Broeckel, MD , Amy Turner, BS
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    MAR 27, 2018 | 9:00 AM
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
    Speaker: Amanda Haas
    Sponsored By: Horizon Discovery
    23 15
    MAR 22, 2018 | 9:00 AM
    Differentiation sensitizes stem-like glioblastoma tumor-initiating cells to mechanical inputs
    Differentiation sensitizes stem-like glioblastoma tumor-initiating...
    DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
    Speaker: Jasmine Hughes
    Sponsored By: Thermo Fisher Scientific/Gibco
    6 4
     
     
  • MAR 15, 2018 | 10:30 AM
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies for Novel Therapy Development
    Overcoming Hurdles in the Study of Rare Diseases: Innovative Strategies...
    The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
    Speaker: Jill Weimer, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    MAR 14, 2018 | 9:00 AM
    IPSC-Derived Human Neurons: Introduction and Application
    IPSC-Derived Human Neurons: Introduction and Application
    Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
    Speaker: Michael Hendrickson
    Presented at: Neuroscience Virtual Event Series 2018
    Sponsored By: BrainXell
    3 1
    MAR 01, 2018 | 12:00 AM
    Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
    Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
    The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
    Speaker: William Hendriks
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    2
    FEB 28, 2018 | 12:00 AM
    Improved Neuronal Performance with the Gibco B-27 Plus Culture System
    Improved Neuronal Performance with the Gibco B-27 Plus Culture...
    TBD...
    Speaker: David Kuninger, PhD
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    2
    JAN 25, 2018 | 8:00 AM
    WEBINAR:  Understanding Immunosuppressive Myeloid Cells and Immunotherapy using Proteome Profiler™ Arrays
    WEBINAR: Understanding Immunosuppressive Myeloid Cells and Immunotherapy...
    DATE: January 25, 2018TIME:  8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
    Speaker: Xin Lu, PhD
    Sponsored By: ACD - A Bio-Techne Brand
    6
     
     
  • JAN 01, 2018 | 10:00 AM
    Disease modelling with human pluripotent stem cells: general principles and specific applications to obesity
    Disease modelling with human pluripotent stem cells: general principles...
    The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
    Speaker: Florian Merkle
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    2
    JAN 01, 2018 | 12:00 AM
    Human stem cells for modelling neurological disease and its therapeutic applications
    Human stem cells for modelling neurological disease and its therapeutic...
    My talk shall encompass how the stem cell research field has evolved from embryonic stem cells to adult stem cells and currently induced pluripotent stem cells with special reference to the f...
    Speaker: Rakhi Pal
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    2
    DEC 01, 2017 | 12:00 AM
    Beyond Automated iPSC reprogramming: applications for a fully automated cell culture system for pluripotent stem cell research
    Beyond Automated iPSC reprogramming: applications for a fully...
    The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
    Speaker: Daniel Paull
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    1
    NOV 16, 2017 | 9:00 AM
    WEBINAR: Breaking Bad with 3D: The development of high throughput screening platforms to interrogate physiologically relevant models
    WEBINAR: Breaking Bad with 3D: The development of high throughput...
    DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
    Speaker: Madhu Nag, PhD
    Sponsored By: Revvity
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