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    Systems Biology

    Systems Biology: Systems biology is the computational and mathematical modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach to biological research.

    Webinars

    • MAR 20, 2014 | 6:00 AM
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
      Speaker: Scott W. Emmons, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      54
      MAR 19, 2014 | 1:00 PM
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
      Speaker: Radosveta Koldamova, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      56
      MAR 19, 2014 | 1:00 PM
      Engineering reproducible neural tissue from pluripotent stem cells
      Engineering reproducible neural tissue from pluripotent stem cells
      The Willerth lab investigates how to engineer neural tissue by combining pluripotent stem cells, controlled drug delivery and biomaterial scaffolds. When generating these replacement tissues,...
      Speaker: Stephanie Willerth, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      70
      MAR 19, 2014 | 12:00 PM
      Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal Coupling in Neuronal Growth Cones
      Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal...
      Axonal growth and pathfinding is fundamental to the development and regeneration of the nervous system. Src tyrosine kinase has been implicated in this process; however, the detailed molecula...
      Speaker: Daniel Suter, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 19, 2014 | 12:00 PM
      Abeta oligomer receptor antagonists as disease-modifying Alzheimers therapeutics
      Abeta oligomer receptor antagonists as disease-modifying Alzheimers...
      Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...
      Speaker: Susan Catalano, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      46
      MAR 19, 2014 | 12:00 PM
      Chemogenetics: a transformational technology for neuroscience
      Chemogenetics: a transformational technology for neuroscience
      ...
      Speaker: Bryan L. Roth, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      162
      MAR 19, 2014 | 10:00 AM
      NMDA receptor regulation in health and disease
      NMDA receptor regulation in health and disease
      Neuron-glial interactions are increasingly recognized as being key for physiological and pathological processes in the central nervous system. Microglia have been found to play a causal role...
      Speaker: Michael Salter, MD, PhD, FRSC
      Presented at: Neuroscience Virtual Event Series 2014
      54
      MAR 19, 2014 | 9:00 AM
      Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic Plasticity
      Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic...
      Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
      Speaker: Kristen Harris, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      24
      MAR 19, 2014 | 8:00 AM
      BRAIN Initiative Panel Discussion - science overview
      BRAIN Initiative Panel Discussion - science overview
      The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
      Speaker: Emery N. Brown, MD, PhD, William Newsome, PhD, Justin Sanchez, PhD, Terrence J Sejnowski, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      59
      MAR 19, 2014 | 7:00 AM
      A Unique B Cell Derived Signature of Multiple Sclerosis and its Biologic Implications
      A Unique B Cell Derived Signature of Multiple Sclerosis and its...
      Multiple Sclerosis (MS) is an autoimmune disease that leads to widespread pathology within the central nervous system (CNS) and is the most common cause of neurologic disability among young a...
      Speaker: Benjamin Greenberg, MD
      Presented at: Neuroscience Virtual Event Series 2014
      34
      MAR 19, 2014 | 7:00 AM
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
      Speaker: Ahmad Salehi, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      15
      MAR 19, 2014 | 6:00 AM
      The Novel Neurotechnology: implications for science, medicine and society
      The Novel Neurotechnology: implications for science, medicine...
      In physical systems built with many components, emergent properties, such as magnetism, are often generated from the interactions among these particles. These emergent properties are often in...
      Speaker: Rafael Yuste, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      138
      FEB 06, 2014 | 12:00 PM
      Your role in the design and construction of an animal facility
      Your role in the design and construction of an animal facility
      Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
      Speaker: Paulina Bugyis, International AIA
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 11:00 AM
      Formation of Bacterial Biofilms
      Formation of Bacterial Biofilms
      Biofilms, are defined as communities of microorganisms that grow embedded in a self-generated matrix of exopolysaccharides and adhered to an inert surface or a live tissue. They are formed 95...
      Speaker: Yvonne M Heuze de lcaza, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 10:00 AM
      Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community of Scholars
      Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community...
      A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
      Speaker: Hugh Hammer, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 9:00 AM
      C.E. CREDITS
      Zebrafish Husbandry An Overview of Successful Practices
      Zebrafish Husbandry An Overview of Successful Practices
      As the prevalence of the use of Zebrafish as an animal model continues its ballistic growth, the need for a better understanding of the factors that add up to success is needed. Topics cover...
      Speaker: Erik Sanders, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      11
      FEB 05, 2014 | 2:00 PM
      Behavioral Management Strategies that Allow Nonhuman Primates to Voluntarily Participate in Their Own Care
      Behavioral Management Strategies that Allow Nonhuman Primates...
      Nonhuman primates in captivity are typically provided with a multitude of behavioral management opportunities, including naturalistic social groupings, foraging devices, complex physical envi...
      Speaker: Steven J Schapiro
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 2:00 PM
      Rodent Health Surveillance:  Innovation driving changes
      Rodent Health Surveillance: Innovation driving changes
      Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
      Speaker: Charles Clifford, DVM, PhD, DACVP
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      4
      FEB 05, 2014 | 11:00 AM
      C.E. CREDITS
      A Good Life for Laboratory Animals
      A Good Life for Laboratory Animals
      Almost all discussion to date on the ethics of animal use in research has revolved around the balance of harms (to the animals) versus benefits (to us) associated with conducting the researc...
      Speaker: Daniel Weary, Dphil
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      100
      FEB 05, 2014 | 10:00 AM
      C.E. CREDITS
      Right-Sizing Small Animal Anesthesia
      Right-Sizing Small Animal Anesthesia
      An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scien...
      Speaker: Andrew H Ide, BS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      13
      FEB 05, 2014 | 10:00 AM
      Building a better rat cage: The impact of color on the laboratory rat?
      Building a better rat cage: The impact of color on the laboratory...
      In the laboratory setting, rats are commonly housed in clear caging in brightly lit rooms. As their natural history suggests a preference for low-light conditions, this practice is likely str...
      Speaker: Melissa Swan, RVT, AAS, RALAT
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 9:00 AM
      What Germs? Hiring and Training Gnotobiotic Technicians
      What Germs? Hiring and Training Gnotobiotic Technicians
      The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
      Speaker: Michelle Hull, MS RLATg
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      3
      FEB 05, 2014 | 6:00 AM
      C.E. CREDITS
      Bedding vs. Thermoregulation
      Bedding vs. Thermoregulation
      This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
      Speaker: Andrea Gay
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      28
      OCT 17, 2013 | 3:00 PM
      C.E. CREDITS
      From Genomic Questions to Clinical Answers in Cancer
      From Genomic Questions to Clinical Answers in Cancer
      Although genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with cancer, the contribution to risk of these variants is small, rende...
      Speaker: Kenan Onel MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      46
    MAR 20, 2014 | 6:00 AM
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
    Speaker: Scott W. Emmons, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    54
    MAR 19, 2014 | 1:00 PM
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
    Speaker: Radosveta Koldamova, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    56
    MAR 19, 2014 | 1:00 PM
    Engineering reproducible neural tissue from pluripotent stem cells
    Engineering reproducible neural tissue from pluripotent stem cells
    The Willerth lab investigates how to engineer neural tissue by combining pluripotent stem cells, controlled drug delivery and biomaterial scaffolds. When generating these replacement tissues,...
    Speaker: Stephanie Willerth, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    70
    MAR 19, 2014 | 12:00 PM
    Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal Coupling in Neuronal Growth Cones
    Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal...
    Axonal growth and pathfinding is fundamental to the development and regeneration of the nervous system. Src tyrosine kinase has been implicated in this process; however, the detailed molecula...
    Speaker: Daniel Suter, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 19, 2014 | 12:00 PM
    Abeta oligomer receptor antagonists as disease-modifying Alzheimers therapeutics
    Abeta oligomer receptor antagonists as disease-modifying Alzheimers...
    Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...
    Speaker: Susan Catalano, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    46
     
     
  • MAR 19, 2014 | 12:00 PM
    Chemogenetics: a transformational technology for neuroscience
    Chemogenetics: a transformational technology for neuroscience
    ...
    Speaker: Bryan L. Roth, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    162
    MAR 19, 2014 | 10:00 AM
    NMDA receptor regulation in health and disease
    NMDA receptor regulation in health and disease
    Neuron-glial interactions are increasingly recognized as being key for physiological and pathological processes in the central nervous system. Microglia have been found to play a causal role...
    Speaker: Michael Salter, MD, PhD, FRSC
    Presented at: Neuroscience Virtual Event Series 2014
    54
    MAR 19, 2014 | 9:00 AM
    Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic Plasticity
    Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic...
    Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
    Speaker: Kristen Harris, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    24
    MAR 19, 2014 | 8:00 AM
    BRAIN Initiative Panel Discussion - science overview
    BRAIN Initiative Panel Discussion - science overview
    The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
    Speaker: Emery N. Brown, MD, PhD, William Newsome, PhD, Justin Sanchez, PhD, Terrence J Sejnowski, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    59
    MAR 19, 2014 | 7:00 AM
    A Unique B Cell Derived Signature of Multiple Sclerosis and its Biologic Implications
    A Unique B Cell Derived Signature of Multiple Sclerosis and its...
    Multiple Sclerosis (MS) is an autoimmune disease that leads to widespread pathology within the central nervous system (CNS) and is the most common cause of neurologic disability among young a...
    Speaker: Benjamin Greenberg, MD
    Presented at: Neuroscience Virtual Event Series 2014
    34
     
     
  • MAR 19, 2014 | 7:00 AM
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
    Speaker: Ahmad Salehi, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    15
    MAR 19, 2014 | 6:00 AM
    The Novel Neurotechnology: implications for science, medicine and society
    The Novel Neurotechnology: implications for science, medicine...
    In physical systems built with many components, emergent properties, such as magnetism, are often generated from the interactions among these particles. These emergent properties are often in...
    Speaker: Rafael Yuste, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    138
    FEB 06, 2014 | 12:00 PM
    Your role in the design and construction of an animal facility
    Your role in the design and construction of an animal facility
    Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
    Speaker: Paulina Bugyis, International AIA
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 06, 2014 | 11:00 AM
    Formation of Bacterial Biofilms
    Formation of Bacterial Biofilms
    Biofilms, are defined as communities of microorganisms that grow embedded in a self-generated matrix of exopolysaccharides and adhered to an inert surface or a live tissue. They are formed 95...
    Speaker: Yvonne M Heuze de lcaza, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 06, 2014 | 10:00 AM
    Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community of Scholars
    Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community...
    A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
    Speaker: Hugh Hammer, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
     
     
  • FEB 06, 2014 | 9:00 AM
    C.E. CREDITS
    Zebrafish Husbandry An Overview of Successful Practices
    Zebrafish Husbandry An Overview of Successful Practices
    As the prevalence of the use of Zebrafish as an animal model continues its ballistic growth, the need for a better understanding of the factors that add up to success is needed. Topics cover...
    Speaker: Erik Sanders, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    11
    FEB 05, 2014 | 2:00 PM
    Behavioral Management Strategies that Allow Nonhuman Primates to Voluntarily Participate in Their Own Care
    Behavioral Management Strategies that Allow Nonhuman Primates...
    Nonhuman primates in captivity are typically provided with a multitude of behavioral management opportunities, including naturalistic social groupings, foraging devices, complex physical envi...
    Speaker: Steven J Schapiro
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 2:00 PM
    Rodent Health Surveillance:  Innovation driving changes
    Rodent Health Surveillance: Innovation driving changes
    Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
    Speaker: Charles Clifford, DVM, PhD, DACVP
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    4
    FEB 05, 2014 | 11:00 AM
    C.E. CREDITS
    A Good Life for Laboratory Animals
    A Good Life for Laboratory Animals
    Almost all discussion to date on the ethics of animal use in research has revolved around the balance of harms (to the animals) versus benefits (to us) associated with conducting the researc...
    Speaker: Daniel Weary, Dphil
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    100
    FEB 05, 2014 | 10:00 AM
    C.E. CREDITS
    Right-Sizing Small Animal Anesthesia
    Right-Sizing Small Animal Anesthesia
    An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scien...
    Speaker: Andrew H Ide, BS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    13
     
     
  • FEB 05, 2014 | 10:00 AM
    Building a better rat cage: The impact of color on the laboratory rat?
    Building a better rat cage: The impact of color on the laboratory...
    In the laboratory setting, rats are commonly housed in clear caging in brightly lit rooms. As their natural history suggests a preference for low-light conditions, this practice is likely str...
    Speaker: Melissa Swan, RVT, AAS, RALAT
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 9:00 AM
    What Germs? Hiring and Training Gnotobiotic Technicians
    What Germs? Hiring and Training Gnotobiotic Technicians
    The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
    Speaker: Michelle Hull, MS RLATg
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    3
    FEB 05, 2014 | 6:00 AM
    C.E. CREDITS
    Bedding vs. Thermoregulation
    Bedding vs. Thermoregulation
    This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
    Speaker: Andrea Gay
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    28
    OCT 17, 2013 | 3:00 PM
    C.E. CREDITS
    From Genomic Questions to Clinical Answers in Cancer
    From Genomic Questions to Clinical Answers in Cancer
    Although genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with cancer, the contribution to risk of these variants is small, rende...
    Speaker: Kenan Onel MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    46
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