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    Transcriptional Regulation

    Transcriptional Regulation: In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA, thereby orchestrating gene activity.

    Webinars

    • OCT 24, 2023 | 10:00 AM
      An epic advance in epigenomics: Automated CUT&RUN enables chromatin profiling for scaled research & drug discovery applications
      An epic advance in epigenomics: Automated CUT&RUN enables chromatin...
      Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
      Speaker: Andrea Johnstone, Ph.D. , Lori Euler
      Sponsored By: Beckman Coulter Life Sciences
      30
      FEB 14, 2023 | 10:00 AM
      A spatially-resolved transcriptional atlas of the murine dorsal pontine tegmentum
      A spatially-resolved transcriptional atlas of the murine dorsal...
      Date: February 14, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The dorsal pontine tegmentum (PnTg) is part of the Pons, the largest section of the brainstem. It is a complex region...
      Speaker: Stefano Nardone, PhD , Cory Brannigan
      Sponsored By: Vizgen
      6
      NOV 03, 2022 | 6:00 AM
      Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions
      Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral...
      Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
      Speaker: Mohamed Abdel-Mohsen
      Sponsored By: GenScript
      16
      AUG 16, 2022 | 11:00 AM
      How to Leverage Laser Capture Microdissection Technology for Advanced Oncology Research
      How to Leverage Laser Capture Microdissection Technology for Advanced...
      Date: August 16, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) Understanding genomic variation in the context of cancer is paramount to identifying disease drivers and informing pers...
      Speaker: Katherine Walter
      Sponsored By: Thermo Fisher Scientific
      12
      JUN 30, 2022 | 9:00 AM
      The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf® Gene Expression Test for Kidney Rejection
      The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf®...
      Date: June 30, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Subclinical acute rejection (SubAR) is a significant risk for kidney transplant recipients, affecting 1 in 4 patients. Ea...
      Speaker: Juston Weems, Ph.D.
      Sponsored By: Standard BioTools
      8
      APR 19, 2022 | 1:30 PM
      C.E. CREDITS
      Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular Depletion
      Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular...
      Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
      Speaker: Dante DeAscanis
      Presented at: Genetics Week Virtual Event Series 2022
      Sponsored By: Jumpcode Genomics
      3
      MAR 29, 2022 | 9:00 AM
      Accelerating commercialization with custom OEM solutions and GMP
      Accelerating commercialization with custom OEM solutions and GMP
      Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
      Speaker: Matthew Davies , Amy Webster , Mitch Gore , Renee Rathjen
      Sponsored By: Cytiva, IDT
      5
      NOV 17, 2021 | 7:00 AM
      CRISPR-based transcriptional activation tools for silent genes in filamentous fungi
      CRISPR-based transcriptional activation tools for silent genes...
      DATE: November 17, 2021 TIME: 7:00am PST, 10:00am EST, 4:00pm CET Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of field...
      Speaker: Laszlo Mozsik
      Sponsored By: GenScript
      13 2
      SEP 29, 2021 | 12:00 PM
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
      Speaker: Domenica Martorana, PhD
      Presented at: CRISPR Virtual Event Series 2021
      Sponsored By: QIAGEN
      1
      AUG 25, 2021 | 10:30 AM
      Methods for Culturing Primary Adult CNS Neurons
      Methods for Culturing Primary Adult CNS Neurons
      In 1910, Harrison published the first report of frog embryonic sympathetic ganglia grown in hanging drops of lymph for a few days, where single neurons extended nerve fibers with complex gro...
      Speaker: Erna van Niekerk, Ph.D.
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: Miltenyi Biotec
      2
      JUN 10, 2021 | 10:00 AM
      GABA-receptive microglia selectively sculpt developing inhibitory circuits
      GABA-receptive microglia selectively sculpt developing inhibitory...
      Date: June 10, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Microglia, the primary brain macrophages, regulate a plethora of processes that impact the organization of neural circuits, including sy...
      Speaker: Loic Binan, Ph.D , Emilia Favuzzi, Ph.D
      Sponsored By: Vizgen
      13 3
      JUN 09, 2021 | 7:00 AM
      Preventing cell misidentification in your daily lab routine
      Preventing cell misidentification in your daily lab routine
      Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
      Speaker: Gabriela Saldanha , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      40 3
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      APR 20, 2021 | 9:00 AM
      Enhancer-Promoter Interactome Drives Neuronal Cell Differentiation and Contextualizes Alzheimer's Associated Polymorphisms
      Enhancer-Promoter Interactome Drives Neuronal Cell Differentiation...
      Chromatin Immunoprecipitation, coupled with sequencing, has shaped our understanding of how transcriptional machinery interacts with genomes to facilitate gene regulation. These protein-DNA...
      Speaker: Cory Padilla, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      Sponsored By: Dovetail Genomics
      1
      MAR 23, 2021 | 9:00 AM
      Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
      Targeted degradation of the enhancer lysine acetyltransferases...
      Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
      Speaker: Christopher Ott, PhD , Tim Geiger, PhD
      Sponsored By: ACD - A Bio-Techne Brand
      8
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      FEB 24, 2021 | 7:00 AM
      DeepCLIP: Predicting the effect of mutations on protein-RNA binding with deep learning
      DeepCLIP: Predicting the effect of mutations on protein-RNA binding...
      Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
      Speaker: Thomas Doktor, PhD.
      Sponsored By: GenScript
      12
      DEC 02, 2020 | 8:00 AM
      Optimize your bioprocess - From shaker to bioreactor
      Optimize your bioprocess - From shaker to bioreactor
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      Speaker: Ines Hartmann , David Solbach
      Sponsored By: Eppendorf
      11
      NOV 19, 2020 | 9:00 AM
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
      Speaker: Kok Hao Chen , Alan Mullan, PhD
      Sponsored By: Andor
      6 2
      NOV 16, 2020 | 8:00 AM
      Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
      Targeted single-cell RNA sequencing enables genome-scale CRISPR...
      Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
      Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
      Sponsored By: Illumina
      11
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      OCT 08, 2020 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      33 5
      OCT 08, 2020 | 12:00 AM
      Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
      Transcriptome analysis of breast cancer clinical specimens with...
      Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
      Speaker: Masahito Kawazu, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
    OCT 24, 2023 | 10:00 AM
    An epic advance in epigenomics: Automated CUT&RUN enables chromatin profiling for scaled research & drug discovery applications
    An epic advance in epigenomics: Automated CUT&RUN enables chromatin...
    Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
    Speaker: Andrea Johnstone, Ph.D. , Lori Euler
    Sponsored By: Beckman Coulter Life Sciences
    30
    FEB 14, 2023 | 10:00 AM
    A spatially-resolved transcriptional atlas of the murine dorsal pontine tegmentum
    A spatially-resolved transcriptional atlas of the murine dorsal...
    Date: February 14, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The dorsal pontine tegmentum (PnTg) is part of the Pons, the largest section of the brainstem. It is a complex region...
    Speaker: Stefano Nardone, PhD , Cory Brannigan
    Sponsored By: Vizgen
    6
    NOV 03, 2022 | 6:00 AM
    Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions
    Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral...
    Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
    Speaker: Mohamed Abdel-Mohsen
    Sponsored By: GenScript
    16
    AUG 16, 2022 | 11:00 AM
    How to Leverage Laser Capture Microdissection Technology for Advanced Oncology Research
    How to Leverage Laser Capture Microdissection Technology for Advanced...
    Date: August 16, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) Understanding genomic variation in the context of cancer is paramount to identifying disease drivers and informing pers...
    Speaker: Katherine Walter
    Sponsored By: Thermo Fisher Scientific
    12
    JUN 30, 2022 | 9:00 AM
    The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf® Gene Expression Test for Kidney Rejection
    The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf®...
    Date: June 30, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Subclinical acute rejection (SubAR) is a significant risk for kidney transplant recipients, affecting 1 in 4 patients. Ea...
    Speaker: Juston Weems, Ph.D.
    Sponsored By: Standard BioTools
    8
     
     
  • APR 19, 2022 | 1:30 PM
    C.E. CREDITS
    Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular Depletion
    Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular...
    Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
    Speaker: Dante DeAscanis
    Presented at: Genetics Week Virtual Event Series 2022
    Sponsored By: Jumpcode Genomics
    3
    MAR 29, 2022 | 9:00 AM
    Accelerating commercialization with custom OEM solutions and GMP
    Accelerating commercialization with custom OEM solutions and GMP
    Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
    Speaker: Matthew Davies , Amy Webster , Mitch Gore , Renee Rathjen
    Sponsored By: Cytiva, IDT
    5
    NOV 17, 2021 | 7:00 AM
    CRISPR-based transcriptional activation tools for silent genes in filamentous fungi
    CRISPR-based transcriptional activation tools for silent genes...
    DATE: November 17, 2021 TIME: 7:00am PST, 10:00am EST, 4:00pm CET Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of field...
    Speaker: Laszlo Mozsik
    Sponsored By: GenScript
    13 2
    SEP 29, 2021 | 12:00 PM
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
    Speaker: Domenica Martorana, PhD
    Presented at: CRISPR Virtual Event Series 2021
    Sponsored By: QIAGEN
    1
    AUG 25, 2021 | 10:30 AM
    Methods for Culturing Primary Adult CNS Neurons
    Methods for Culturing Primary Adult CNS Neurons
    In 1910, Harrison published the first report of frog embryonic sympathetic ganglia grown in hanging drops of lymph for a few days, where single neurons extended nerve fibers with complex gro...
    Speaker: Erna van Niekerk, Ph.D.
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: Miltenyi Biotec
    2
     
     
  • JUN 10, 2021 | 10:00 AM
    GABA-receptive microglia selectively sculpt developing inhibitory circuits
    GABA-receptive microglia selectively sculpt developing inhibitory...
    Date: June 10, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Microglia, the primary brain macrophages, regulate a plethora of processes that impact the organization of neural circuits, including sy...
    Speaker: Loic Binan, Ph.D , Emilia Favuzzi, Ph.D
    Sponsored By: Vizgen
    13 3
    JUN 09, 2021 | 7:00 AM
    Preventing cell misidentification in your daily lab routine
    Preventing cell misidentification in your daily lab routine
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    Speaker: Gabriela Saldanha , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    40 3
    MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    APR 20, 2021 | 9:00 AM
    Enhancer-Promoter Interactome Drives Neuronal Cell Differentiation and Contextualizes Alzheimer's Associated Polymorphisms
    Enhancer-Promoter Interactome Drives Neuronal Cell Differentiation...
    Chromatin Immunoprecipitation, coupled with sequencing, has shaped our understanding of how transcriptional machinery interacts with genomes to facilitate gene regulation. These protein-DNA...
    Speaker: Cory Padilla, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    Sponsored By: Dovetail Genomics
    1
    MAR 23, 2021 | 9:00 AM
    Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
    Targeted degradation of the enhancer lysine acetyltransferases...
    Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
    Speaker: Christopher Ott, PhD , Tim Geiger, PhD
    Sponsored By: ACD - A Bio-Techne Brand
    8
     
     
  • FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
    FEB 24, 2021 | 7:00 AM
    DeepCLIP: Predicting the effect of mutations on protein-RNA binding with deep learning
    DeepCLIP: Predicting the effect of mutations on protein-RNA binding...
    Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
    Speaker: Thomas Doktor, PhD.
    Sponsored By: GenScript
    12
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
    NOV 19, 2020 | 9:00 AM
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
    Speaker: Kok Hao Chen , Alan Mullan, PhD
    Sponsored By: Andor
    6 2
    NOV 16, 2020 | 8:00 AM
    Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
    Targeted single-cell RNA sequencing enables genome-scale CRISPR...
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
    Sponsored By: Illumina
    11
     
     
  • NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
    OCT 08, 2020 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    33 5
    OCT 08, 2020 | 12:00 AM
    Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
    Transcriptome analysis of breast cancer clinical specimens with...
    Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
    Speaker: Masahito Kawazu, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
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