This event is now apart of the Neuroscience Virtual Event Series. Labroots' two-day international Laboratory Animal Science (LAS) virtual conference, that took place on February 3rd and ...
The fate of all but a very few laboratory animals is to be killed at the end of their experimental lives. There is a moral responsibility to give the animals used in science a humane death by...
In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently. With regard to scientific public...
Animal studies performed on behalf of GlaxoSmithKline (GSK) are expected to uphold the core principles established by Corporate Policy 403, ‘Care, Welfare and Treatment of Animals by GS...
DATE: February 3rd, 2016
TIME: 10am pacific time, 1pm eastern time
Instituting a laboratory outreach program achieves a multitude of benefits beyond driving optimization, test...
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
Quality animal research is based on quality animal care and use. This is achieved by coordinating several key personnel and activities, and implementing appropriate animal care and use proced...
Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
An industry leader in delivering instrument systems, reagents, and services to life science researchers,Beckman Coulter Life Sciences helps enable new discoveries in biology-based research...
January 28, 2016, 8:00am PT, 11:00am ET, 3:00pm GMT
The relationship of particle size distribution (PSD) in cement and its impact on both strength and curing time of concrete make PSD crit...
DATE: January 26th, 2016
TIME: 8am pacific, 11am eastern
PTEN gene loss occurs frequently in castration-resistant prostate cancer (CRPC) and may drive progression through activation of th...
DATE: January 21, 2016
TIME: 8am Pacific time, 11am Eastern time
In this webinar, you will learn:
basics of pooled lentiviral screening workflows
implications of ...
Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
DATE: January 15, 2016
TIME: 7am EST, 12pm UK, 1pm CET
With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
January 12, 2016, 8:00am PT, 11:00am ET, 3:00pm GMT
Targeted nanoparticle applications have become a major focus of translational development of both diagnostics and therapeutics for clini...
Innate Lymphoid Cells (ILC) are lymphocytes that share the same morphological features of classical lymphocytes. They lack specific antigen receptors (Spits and Cupedo Annu Rev Immunol 2012)....
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
In this webinar, you will learn about an innovative approach to a traditional technology which encompasses several advanced features that are unusual for a flow cytometer. For example, ...
We compared the workflow of the Beckman Coulter automated Aquios CL flow cytometer, using AQUIOS Tetra software, to a single platform method using the Beckman Coulter TQ-Prep lysing system wi...
November 5, 2015, 8:00am PT, 11:00am ET, 3:00pm GMT
T-cells form an integral part of the human immune system by fighting off infection and eliminating transformed cells. Over the last deca...
A fundamental aspect of the thermodynamic characterization of macromolecular complexes is the determination of the component stoichiometry. There are a number of approaches that may be employ...
During the development of oral cancer (OC), cancer-associated fibroblasts (CAFs) create a supporting niche by maintaining a bidirectional crosstalk with cancer cells, mediated by classically ...