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    Assay Development

    Assay Development: one of the first steps in drug development and toxicity testing is creating test systems on which to evaluate the effects of chemical compounds on cellular, molecular or biochemical processes of interest.

    Webinars

    • FEB 22, 2017 | 12:00 PM
      Measurement Assurance for Tissue Engineering & Regenerative Medicine
      Measurement Assurance for Tissue Engineering & Regenerative Medicine
      Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
      Speaker: Carl Simon, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      1
      FEB 20, 2017 | 8:00 AM
      Characterization of Biosimilars by SPR
      Characterization of Biosimilars by SPR
      Development of biosimilars for marketed bio-therapeutics is expected to increase patient access and affordability of these therapeutics within the healthcare system.  One of the key aspe...
      Speaker: Shashank Sunkara
      Presented at: Protein Research Live
      4
      FEB 20, 2017 | 8:00 AM
      SPR - Companion from bench to bedside
      SPR - Companion from bench to bedside
      SPR technology is being improved steadily and today is an essential component in the biopharmaceutical industry. As SPR based assays extract valuable and reliable information at high accuracy...
      Speaker: Markus Sack, MSc
      Presented at: Protein Research Live
      5
      FEB 08, 2017 | 1:30 PM
      Managing genetically modified rodent strains: focus on the genotype and genetic background
      Managing genetically modified rodent strains: focus on the genotype...
      DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETThe powerful and expanding use of genetically modified mice introduces important aspects of genetics in managing these strains for breedi...
      Speaker: Steve Fiering, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      5 1
      FEB 08, 2017 | 1:30 PM
      Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
      Characterization of Niemann Pick Type C mutant mice using automated...
      DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
      Speaker: Sangeetha Iyer, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      1
      JAN 27, 2017 | 4:00 AM
      WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity Through Time and Space by Mass Cytometry
      WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity...
      DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
      Speaker: Bernd Bodenmiller, PhD , Randall Wetzel, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      16
      JAN 26, 2017 | 8:00 AM
      WEBINAR: Fast, Simple and Sensitive Electrochemical Biosensing using Screen-Printed Electrodes: A high throughput solution
      WEBINAR: Fast, Simple and Sensitive Electrochemical Biosensing...
      DATE:  January 26, 2017TIME: 8:00am PT, 11:00am ETThe demand for low-cost, disposable devices with short response times capable of performing routine electrochemical biosensing has...
      Speaker: Susana Campuzano, PhD , Laura Fernández Llano, PhD
      Sponsored By: Metrohm USA
      12
      JAN 19, 2017 | 8:00 AM
      Webinar: Detecting meaningful mutations from liquid biopsies by Anchored Multiplex PCR
      Webinar: Detecting meaningful mutations from liquid biopsies by...
      DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
      Speaker: Josh Stahl , Jonathan Doose
      Sponsored By: ArcherDX, ArcherDX
      9
      JAN 17, 2017 | 8:00 AM
      An Introduction to In-Cell ELISA
      An Introduction to In-Cell ELISA
      In-Cell ELISA, is a well-accepted assay approach to perform quantitative immunocytochemistry of cultured cells using either a colormetric or fluorometric readout.  Join our In-Cell ELISA...
      Speaker: John Constable, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      JAN 17, 2017 | 8:00 AM
      Benefits and limitations of primary and secondary antibody conjugates
      Benefits and limitations of primary and secondary antibody conjugates
      Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
      Speaker: Javier Vancells, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      DEC 14, 2016 | 7:30 AM
      Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
      Advances in modeling human diseases using induced pluripotent...
      DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
      Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      7 1
      DEC 07, 2016 | 9:00 AM
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
      Speaker: Edgar Jacoby, Ph.D.
      Sponsored By: DiscoverX, DiscoverX
      4
      DEC 01, 2016 | 8:00 AM
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
      DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
      Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
      Sponsored By: Revvity
      3
      NOV 23, 2016 | 8:00 AM
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
      Speaker: Moritz Voelker-Albert , Andreas Schmidt
      Sponsored By: SCIEX OMICS, SCIEX OMICS
      24
      NOV 17, 2016 | 8:30 AM
      Simultaneous, single-cell visualization of RNA and Protein
      Simultaneous, single-cell visualization of RNA and Protein
      DATE: November 17, 2016 TIME: 8:30am PT, 11:30am ET The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
      Speaker: Sara Becker-Catania, PhD
      Sponsored By: eBioscience Business Unit, Thermo Fisher Scientific, eBioscience Business Unit, Thermo Fisher Scientific
      4
      NOV 09, 2016 | 9:00 AM
      A duplexed assay to measure GPCR-mediated calcium signaling and β-Arrestin recruitment from single well using FDSS/µCell functional screening system
      A duplexed assay to measure GPCR-mediated calcium signaling and...
      DATE: November 9th, 2016 TIME: 9:00 AM PT, 12:00 PM ET The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...
      Speaker: Thierry Calmels, PhD
      Sponsored By: DiscoverX, DiscoverX
      3
      NOV 08, 2016 | 6:00 AM
      New Approaches to Antibody Validation Using Immunoprecipitation and Mass Spectrometry
      New Approaches to Antibody Validation Using Immunoprecipitation...
      Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications.  Hundreds of thousands o...
      Speaker: John Rogers, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      9 2
      NOV 03, 2016 | 1:30 PM
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
      We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
      Speaker: Fabrizio Bonelli, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 03, 2016 | 12:00 PM
      Point of Care Testing - Why Knowing Now Matters in the Emergency Department
      Point of Care Testing - Why Knowing Now Matters in the Emergency...
      There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes.  There is an association between waiting times and short term mo...
      Speaker: Ellis Jacobs, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      0
      NOV 03, 2016 | 12:00 PM
      Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate Precision in Breast Cancer Targeted Therapy
      Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate...
      Breast cancer is a complex heterogeneous disease, with each subtype characterized by distinct clinical features and molecular alterations. The heterogeneity of breast cancer has presented mas...
      Speaker: Julie Deschenes, MBA, PhD , Dilhan Weeraratne, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 03, 2016 | 10:30 AM
      Rapid, Low-cost Tools for Global Health:  Using Cell-free Synthetic Biology for Zika Virus Detection and the Portable Manufacture of Therapeutics
      Rapid, Low-cost Tools for Global Health: Using Cell-free Synthetic...
      The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions.  In early 2016 we developed a pipe...
      Speaker: Keith Pardee, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 03, 2016 | 10:30 AM
      Found in Translation: ST2 From Discovery to Clinical Adoption
      Found in Translation: ST2 From Discovery to Clinical Adoption
      Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
      Speaker: James Snider, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 03, 2016 | 10:30 AM
      The High Resolution Solution: Accurate Mass for the Clinical Research Laboratory
      The High Resolution Solution: Accurate Mass for the Clinical Research...
      Liquid chromatography high resolution time-of-flight mass spectrometry (LC-TOF-MS) is becoming increasingly popular in the clinical research laboratory. It can offer higher throughput and sup...
      Speaker: Natalie Rasmussen
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 03, 2016 | 9:00 AM
      KEYNOTE: Big data and the learning healthcare system: practical applications for the clinical laboratory
      KEYNOTE: Big data and the learning healthcare system: practical...
      The aim of the learning healthcare system is to leverage data stored in the electronic health record (EHR) to gain insights into and improve healthcare delivery. Laboratory testing represents...
      Speaker: Lee Schroeder, MD, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
    FEB 22, 2017 | 12:00 PM
    Measurement Assurance for Tissue Engineering & Regenerative Medicine
    Measurement Assurance for Tissue Engineering & Regenerative Medicine
    Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
    Speaker: Carl Simon, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    1
    FEB 20, 2017 | 8:00 AM
    Characterization of Biosimilars by SPR
    Characterization of Biosimilars by SPR
    Development of biosimilars for marketed bio-therapeutics is expected to increase patient access and affordability of these therapeutics within the healthcare system.  One of the key aspe...
    Speaker: Shashank Sunkara
    Presented at: Protein Research Live
    4
    FEB 20, 2017 | 8:00 AM
    SPR - Companion from bench to bedside
    SPR - Companion from bench to bedside
    SPR technology is being improved steadily and today is an essential component in the biopharmaceutical industry. As SPR based assays extract valuable and reliable information at high accuracy...
    Speaker: Markus Sack, MSc
    Presented at: Protein Research Live
    5
    FEB 08, 2017 | 1:30 PM
    Managing genetically modified rodent strains: focus on the genotype and genetic background
    Managing genetically modified rodent strains: focus on the genotype...
    DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETThe powerful and expanding use of genetically modified mice introduces important aspects of genetics in managing these strains for breedi...
    Speaker: Steve Fiering, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    5 1
    FEB 08, 2017 | 1:30 PM
    Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
    Characterization of Niemann Pick Type C mutant mice using automated...
    DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
    Speaker: Sangeetha Iyer, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    1
     
     
  • JAN 27, 2017 | 4:00 AM
    WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity Through Time and Space by Mass Cytometry
    WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity...
    DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
    Speaker: Bernd Bodenmiller, PhD , Randall Wetzel, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    16
    JAN 26, 2017 | 8:00 AM
    WEBINAR: Fast, Simple and Sensitive Electrochemical Biosensing using Screen-Printed Electrodes: A high throughput solution
    WEBINAR: Fast, Simple and Sensitive Electrochemical Biosensing...
    DATE:  January 26, 2017TIME: 8:00am PT, 11:00am ETThe demand for low-cost, disposable devices with short response times capable of performing routine electrochemical biosensing has...
    Speaker: Susana Campuzano, PhD , Laura Fernández Llano, PhD
    Sponsored By: Metrohm USA
    12
    JAN 19, 2017 | 8:00 AM
    Webinar: Detecting meaningful mutations from liquid biopsies by Anchored Multiplex PCR
    Webinar: Detecting meaningful mutations from liquid biopsies by...
    DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
    Speaker: Josh Stahl , Jonathan Doose
    Sponsored By: ArcherDX, ArcherDX
    9
    JAN 17, 2017 | 8:00 AM
    An Introduction to In-Cell ELISA
    An Introduction to In-Cell ELISA
    In-Cell ELISA, is a well-accepted assay approach to perform quantitative immunocytochemistry of cultured cells using either a colormetric or fluorometric readout.  Join our In-Cell ELISA...
    Speaker: John Constable, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
    JAN 17, 2017 | 8:00 AM
    Benefits and limitations of primary and secondary antibody conjugates
    Benefits and limitations of primary and secondary antibody conjugates
    Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
    Speaker: Javier Vancells, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
     
     
  • DEC 14, 2016 | 7:30 AM
    Advances in modeling human diseases using induced pluripotent stem cell-derived cellular models
    Advances in modeling human diseases using induced pluripotent...
    DATE: December 14, 2016 TIME: 7:30am PT, 10:30am ET A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
    Speaker: T.K. Feaster, PhD , Kile Mangan, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    7 1
    DEC 07, 2016 | 9:00 AM
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
    Speaker: Edgar Jacoby, Ph.D.
    Sponsored By: DiscoverX, DiscoverX
    4
    DEC 01, 2016 | 8:00 AM
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
    DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
    Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
    Sponsored By: Revvity
    3
    NOV 23, 2016 | 8:00 AM
    Studying Kinetics of Chromatin Assembly with SWATH-MS
    Studying Kinetics of Chromatin Assembly with SWATH-MS
    DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
    Speaker: Moritz Voelker-Albert , Andreas Schmidt
    Sponsored By: SCIEX OMICS, SCIEX OMICS
    24
    NOV 17, 2016 | 8:30 AM
    Simultaneous, single-cell visualization of RNA and Protein
    Simultaneous, single-cell visualization of RNA and Protein
    DATE: November 17, 2016 TIME: 8:30am PT, 11:30am ET The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
    Speaker: Sara Becker-Catania, PhD
    Sponsored By: eBioscience Business Unit, Thermo Fisher Scientific, eBioscience Business Unit, Thermo Fisher Scientific
    4
     
     
  • NOV 09, 2016 | 9:00 AM
    A duplexed assay to measure GPCR-mediated calcium signaling and β-Arrestin recruitment from single well using FDSS/µCell functional screening system
    A duplexed assay to measure GPCR-mediated calcium signaling and...
    DATE: November 9th, 2016 TIME: 9:00 AM PT, 12:00 PM ET The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...
    Speaker: Thierry Calmels, PhD
    Sponsored By: DiscoverX, DiscoverX
    3
    NOV 08, 2016 | 6:00 AM
    New Approaches to Antibody Validation Using Immunoprecipitation and Mass Spectrometry
    New Approaches to Antibody Validation Using Immunoprecipitation...
    Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications.  Hundreds of thousands o...
    Speaker: John Rogers, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    9 2
    NOV 03, 2016 | 1:30 PM
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
    We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
    Speaker: Fabrizio Bonelli, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 03, 2016 | 12:00 PM
    Point of Care Testing - Why Knowing Now Matters in the Emergency Department
    Point of Care Testing - Why Knowing Now Matters in the Emergency...
    There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes.  There is an association between waiting times and short term mo...
    Speaker: Ellis Jacobs, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    0
    NOV 03, 2016 | 12:00 PM
    Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate Precision in Breast Cancer Targeted Therapy
    Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate...
    Breast cancer is a complex heterogeneous disease, with each subtype characterized by distinct clinical features and molecular alterations. The heterogeneity of breast cancer has presented mas...
    Speaker: Julie Deschenes, MBA, PhD , Dilhan Weeraratne, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
     
     
  • NOV 03, 2016 | 10:30 AM
    Rapid, Low-cost Tools for Global Health:  Using Cell-free Synthetic Biology for Zika Virus Detection and the Portable Manufacture of Therapeutics
    Rapid, Low-cost Tools for Global Health: Using Cell-free Synthetic...
    The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be rapidly developed for distribution and use in pandemic regions.  In early 2016 we developed a pipe...
    Speaker: Keith Pardee, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 03, 2016 | 10:30 AM
    Found in Translation: ST2 From Discovery to Clinical Adoption
    Found in Translation: ST2 From Discovery to Clinical Adoption
    Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
    Speaker: James Snider, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 03, 2016 | 10:30 AM
    The High Resolution Solution: Accurate Mass for the Clinical Research Laboratory
    The High Resolution Solution: Accurate Mass for the Clinical Research...
    Liquid chromatography high resolution time-of-flight mass spectrometry (LC-TOF-MS) is becoming increasingly popular in the clinical research laboratory. It can offer higher throughput and sup...
    Speaker: Natalie Rasmussen
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 03, 2016 | 9:00 AM
    KEYNOTE: Big data and the learning healthcare system: practical applications for the clinical laboratory
    KEYNOTE: Big data and the learning healthcare system: practical...
    The aim of the learning healthcare system is to leverage data stored in the electronic health record (EHR) to gain insights into and improve healthcare delivery. Laboratory testing represents...
    Speaker: Lee Schroeder, MD, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
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