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    Assay Development

    Assay Development: one of the first steps in drug development and toxicity testing is creating test systems on which to evaluate the effects of chemical compounds on cellular, molecular or biochemical processes of interest.

    Webinars

    • NOV 03, 2016 | 7:30 AM
      Fusion genes:  what , why and how
      Fusion genes: what , why and how
      Fusion genes are hybrid genes formed by the fusion of two separate genes. Translocation, interstitial deletion and chromosomal inversions are some of the genetic events that can lead to the f...
      Speaker: Raed Samara, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 03, 2016 | 6:00 AM
      Mutation Detection Simplified: From Liquid Biopsy in clinical oncology to the detection of Drug Resistance Associated Mutations in virology
      Mutation Detection Simplified: From Liquid Biopsy in clinical...
      Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades.  Next-Generation Sequencing (NGS) technology r...
      Speaker: Gerd Michel, PhD , Lou Welebob
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      5
      NOV 03, 2016 | 6:00 AM
      Automation and core-laboratory: experience of a large European academic hospital
      Automation and core-laboratory: experience of a large European...
      Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
      Speaker: Damien Gruson, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 03, 2016 | 6:00 AM
      IQCP is a four letter word
      IQCP is a four letter word
      IQCP represents a new approach to quality control for clinical laboratories.  Beginning in 2016 clinical laboratories were tasked with developing individualized quality control plans for...
      Speaker: Steven Cotten, PhD DABCC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      5
      NOV 02, 2016 | 1:30 PM
      A Platform to Digitize Biology: A Potential Pathway to Exponential Medicine
      A Platform to Digitize Biology: A Potential Pathway to Exponential...
      Today there are about 7B mobile phone worldwide and about 50,000 mobile health applications actively changing the landscape of how healthcare will be delivered in the next years. While numero...
      Speaker: John McDevitt, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      4
      NOV 02, 2016 | 12:00 PM
      Immunoassays and Pain Management Drug Testing
      Immunoassays and Pain Management Drug Testing
      In the past several years, there has been an increase in drug testing associated with chronic pain. Immunoassays are the most common method for initial screening which can test for a specific...
      Speaker: Nihmat Morjana, Ph.D., M.Sc.
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 02, 2016 | 10:30 AM
      Tough Targets. Simple Genotyping. Using HRM as a direct approach in research applications.
      Tough Targets. Simple Genotyping. Using HRM as a direct approach...
      Are there DNA targets in your lab that are difficult to genotype using standard PCR or sequencing?Do you ever need to genotype a single sample, and you don’t want to wait to batch sam...
      Speaker: Brian McNally, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 02, 2016 | 10:30 AM
      Urine Drug Testing in Pain Management
      Urine Drug Testing in Pain Management
      With increasing emphasis on effective pain management in clinical care, there has been a significant increase in the number of opioid prescriptions in the past decade.  While these drugs...
      Speaker: William Clarke, PhD, MBA, DABCC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3 1
      NOV 02, 2016 | 10:30 AM
      Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
      Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
      Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
      Speaker: Sebastiano Gattoni-Celli, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 02, 2016 | 9:00 AM
      Vitamin D supplementation in Pregnant Women: Effects on Preeclampsia and Asthma in the Offspring
      Vitamin D supplementation in Pregnant Women: Effects on Preeclampsia...
      Vitamin D insufficiency and deficiency are prevalent worldwide, and pregnant women and infants are at highest risk for having deficiency and related consequences. Epidemiologic studies have s...
      Speaker: Augusto Litonjua, MD, PhD , Scott Weiss, MD, MS
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      4
      NOV 02, 2016 | 7:30 AM
      FDA and Mass Spec Tests for Clinical Labs
      FDA and Mass Spec Tests for Clinical Labs
      Most of the tests performed for patient care use automated colorimetric and immunoassay methods in the clinical laboratories. Clinical labs are regulated by CLIA and are routinely inspected b...
      Speaker: Ravinder Singh, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 02, 2016 | 6:00 AM
      Urine Toxicology Testing in Support of Pain Management
      Urine Toxicology Testing in Support of Pain Management
      Chronic pain is a major problem in most countries. Specialized pain management physicians often see and treat patients with chronic pain, and one type of therapy that may be prescribed is an...
      Speaker: Jennifer Colby, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      4
      NOV 02, 2016 | 6:00 AM
      Fast and easy identification of disease causing variants in hereditary diseases using patient phenotype information and testing for different modes of inheritance
      Fast and easy identification of disease causing variants in hereditary...
      Whole genome and exome sequencing is being widely used to identify disease-causing variants in patients with hereditary and rare diseases. Discovering the true disease-causing variants often...
      Speaker: Anika Joecker, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 01, 2016 | 8:00 AM
      Development of selection strategies for Homologous Recombination Deficient (HRD) patients utilizing a Liquid Biopsy
      Development of selection strategies for Homologous Recombination...
      DATE: November 1, 2016 TIME: 8:00AM PT, 11:00AM ET Metastatic cancer is an evolving, heterogeneous disease that becomes more complex over time through the selection of sub-clonal tumor po...
      Speaker: Mark Landers
      Sponsored By: Epic Sciences, Epic Sciences , Epic Sciences
      4
      OCT 19, 2016 | 9:00 AM
      Controlling RNA-Seq Experiments Using Spike-In RNA Variants
      Controlling RNA-Seq Experiments Using Spike-In RNA Variants
      DATE: October 19, 2016 TIME:  9:00 AM PT, 12:00 PM ET, 6:00 PM CEST    Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
      Speaker: Lukas Paul, PhD
      Sponsored By: Lexogen, Lexogen
      7 2
      OCT 11, 2016 | 7:00 AM
      Cellular Applications for Image-based Cytometry on A Multimode Plate Reader
      Cellular Applications for Image-based Cytometry on A Multimode...
      Date: October 11th, 2016Time: 10:00AM EST, 4:00PM CEST, 3:00PM BST, 7:00AM PSTPlate readers first became available about 30 years ago and have become the workhorses of researc...
      Speaker: Frauke Haenel, PhD , Maria Kuzikov, MSc
      Sponsored By: Revvity
      8 1
      OCT 05, 2016 | 12:00 PM
      Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing the Abundance  of Extremely Rare Mutations Associated with Cancer Diagnosis, Prognosis, and Therapy
      Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing...
      Real-time multiplex PCR assays are potentially the most rapid, most sensitive,and least expensive way to assess the abundance of mutant DNA fragments present in liquid biopsies; provided th...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      OCT 05, 2016 | 10:00 AM
      When Good Biomarkers Go Bad: Effectively Utilizing Procalcitonin (PCT) for Sepsis Management to Demonstrate the Value of the Lab
      When Good Biomarkers Go Bad: Effectively Utilizing Procalcitonin...
      DATE:  October 5, 2016 TIME:  10:00am PT, 1:00pm ET Sepsis, a host-mediated response to a systemic infection, is a leading cause of mortality worldwide (1).  Early recognit...
      Speaker: Joshua Hayden, PhD, DABCC, FACB
      Sponsored By: LabLeaders, LabLeaders
      7 1
      SEP 22, 2016 | 4:00 AM
      Cross-validation of Antibodies Using DigiWest
      Cross-validation of Antibodies Using DigiWest
      DATE: September 22, 2016 TIME:  4:00am PT, 7:00am ET, 11:00am GMT Here, we present a novel approach that combines the principles of the western blot (protein separation by SDS-PAGE; ...
      Speaker: Anthony Couvillon, PhD , Markus Templin, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      3 2
      SEP 20, 2016 | 7:00 AM
      Advanced Analysis of Complex Cell Models with the New Operetta CLS HCA System
      Advanced Analysis of Complex Cell Models with the New Operetta...
      DATE: September 20th, 2016TIME:  7:00AM PST, 10:00AM ETThere is a growing trend towards developing in vitro cell models that recapitulate the in vivo environment in basic research,...
      Speaker: Jacob Tesdorpf, PhD , Joe Trask
      Sponsored By: Revvity
      25
      SEP 08, 2016 | 1:30 PM
      The Paradigm Shift in Clinical Microbiology
      The Paradigm Shift in Clinical Microbiology
      Multi-Drug Resistant Organisms (MDROs) are becoming a bigger and bigger concern throughout the world. Antibiotic resistance forms and spreads faster than pharmaceutical companies have been ab...
      Speaker: Steven Cagas, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      3
      AUG 30, 2016 | 8:00 AM
      Improved differentiation of human pluripotent stem cell-derived neurons through reduction of progenitor proliferation: impact on downstream applications
      Improved differentiation of human pluripotent stem cell-derived...
      Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
      Speaker: David Kuninger, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      1
      JUN 30, 2016 | 8:00 AM
      Surveying expression of immune checkpoint markers in the tissue microenvironment
      Surveying expression of immune checkpoint markers in the tissue...
      DATE:  June 30, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
      Speaker: Jeffrey Kim, PhD
      Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
      3 1
      JUN 30, 2016 | 7:30 AM
      Proteome centric precision medicine:  embracing pathological diversity
      Proteome centric precision medicine: embracing pathological diversity
      Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
      Speaker: Jennifer Van Eyk, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      8
    NOV 03, 2016 | 7:30 AM
    Fusion genes:  what , why and how
    Fusion genes: what , why and how
    Fusion genes are hybrid genes formed by the fusion of two separate genes. Translocation, interstitial deletion and chromosomal inversions are some of the genetic events that can lead to the f...
    Speaker: Raed Samara, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 03, 2016 | 6:00 AM
    Mutation Detection Simplified: From Liquid Biopsy in clinical oncology to the detection of Drug Resistance Associated Mutations in virology
    Mutation Detection Simplified: From Liquid Biopsy in clinical...
    Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades.  Next-Generation Sequencing (NGS) technology r...
    Speaker: Gerd Michel, PhD , Lou Welebob
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    5
    NOV 03, 2016 | 6:00 AM
    Automation and core-laboratory: experience of a large European academic hospital
    Automation and core-laboratory: experience of a large European...
    Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
    Speaker: Damien Gruson, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 03, 2016 | 6:00 AM
    IQCP is a four letter word
    IQCP is a four letter word
    IQCP represents a new approach to quality control for clinical laboratories.  Beginning in 2016 clinical laboratories were tasked with developing individualized quality control plans for...
    Speaker: Steven Cotten, PhD DABCC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    5
    NOV 02, 2016 | 1:30 PM
    A Platform to Digitize Biology: A Potential Pathway to Exponential Medicine
    A Platform to Digitize Biology: A Potential Pathway to Exponential...
    Today there are about 7B mobile phone worldwide and about 50,000 mobile health applications actively changing the landscape of how healthcare will be delivered in the next years. While numero...
    Speaker: John McDevitt, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    4
     
     
  • NOV 02, 2016 | 12:00 PM
    Immunoassays and Pain Management Drug Testing
    Immunoassays and Pain Management Drug Testing
    In the past several years, there has been an increase in drug testing associated with chronic pain. Immunoassays are the most common method for initial screening which can test for a specific...
    Speaker: Nihmat Morjana, Ph.D., M.Sc.
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 02, 2016 | 10:30 AM
    Tough Targets. Simple Genotyping. Using HRM as a direct approach in research applications.
    Tough Targets. Simple Genotyping. Using HRM as a direct approach...
    Are there DNA targets in your lab that are difficult to genotype using standard PCR or sequencing?Do you ever need to genotype a single sample, and you don’t want to wait to batch sam...
    Speaker: Brian McNally, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 02, 2016 | 10:30 AM
    Urine Drug Testing in Pain Management
    Urine Drug Testing in Pain Management
    With increasing emphasis on effective pain management in clinical care, there has been a significant increase in the number of opioid prescriptions in the past decade.  While these drugs...
    Speaker: William Clarke, PhD, MBA, DABCC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3 1
    NOV 02, 2016 | 10:30 AM
    Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
    Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
    Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
    Speaker: Sebastiano Gattoni-Celli, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 02, 2016 | 9:00 AM
    Vitamin D supplementation in Pregnant Women: Effects on Preeclampsia and Asthma in the Offspring
    Vitamin D supplementation in Pregnant Women: Effects on Preeclampsia...
    Vitamin D insufficiency and deficiency are prevalent worldwide, and pregnant women and infants are at highest risk for having deficiency and related consequences. Epidemiologic studies have s...
    Speaker: Augusto Litonjua, MD, PhD , Scott Weiss, MD, MS
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    4
     
     
  • NOV 02, 2016 | 7:30 AM
    FDA and Mass Spec Tests for Clinical Labs
    FDA and Mass Spec Tests for Clinical Labs
    Most of the tests performed for patient care use automated colorimetric and immunoassay methods in the clinical laboratories. Clinical labs are regulated by CLIA and are routinely inspected b...
    Speaker: Ravinder Singh, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 02, 2016 | 6:00 AM
    Urine Toxicology Testing in Support of Pain Management
    Urine Toxicology Testing in Support of Pain Management
    Chronic pain is a major problem in most countries. Specialized pain management physicians often see and treat patients with chronic pain, and one type of therapy that may be prescribed is an...
    Speaker: Jennifer Colby, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    4
    NOV 02, 2016 | 6:00 AM
    Fast and easy identification of disease causing variants in hereditary diseases using patient phenotype information and testing for different modes of inheritance
    Fast and easy identification of disease causing variants in hereditary...
    Whole genome and exome sequencing is being widely used to identify disease-causing variants in patients with hereditary and rare diseases. Discovering the true disease-causing variants often...
    Speaker: Anika Joecker, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
    NOV 01, 2016 | 8:00 AM
    Development of selection strategies for Homologous Recombination Deficient (HRD) patients utilizing a Liquid Biopsy
    Development of selection strategies for Homologous Recombination...
    DATE: November 1, 2016 TIME: 8:00AM PT, 11:00AM ET Metastatic cancer is an evolving, heterogeneous disease that becomes more complex over time through the selection of sub-clonal tumor po...
    Speaker: Mark Landers
    Sponsored By: Epic Sciences, Epic Sciences , Epic Sciences
    4
    OCT 19, 2016 | 9:00 AM
    Controlling RNA-Seq Experiments Using Spike-In RNA Variants
    Controlling RNA-Seq Experiments Using Spike-In RNA Variants
    DATE: October 19, 2016 TIME:  9:00 AM PT, 12:00 PM ET, 6:00 PM CEST    Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
    Speaker: Lukas Paul, PhD
    Sponsored By: Lexogen, Lexogen
    7 2
     
     
  • OCT 11, 2016 | 7:00 AM
    Cellular Applications for Image-based Cytometry on A Multimode Plate Reader
    Cellular Applications for Image-based Cytometry on A Multimode...
    Date: October 11th, 2016Time: 10:00AM EST, 4:00PM CEST, 3:00PM BST, 7:00AM PSTPlate readers first became available about 30 years ago and have become the workhorses of researc...
    Speaker: Frauke Haenel, PhD , Maria Kuzikov, MSc
    Sponsored By: Revvity
    8 1
    OCT 05, 2016 | 12:00 PM
    Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing the Abundance  of Extremely Rare Mutations Associated with Cancer Diagnosis, Prognosis, and Therapy
    Sensitive and Specific, Multiplex, Real-Time PCR Assays for Assessing...
    Real-time multiplex PCR assays are potentially the most rapid, most sensitive,and least expensive way to assess the abundance of mutant DNA fragments present in liquid biopsies; provided th...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
    OCT 05, 2016 | 10:00 AM
    When Good Biomarkers Go Bad: Effectively Utilizing Procalcitonin (PCT) for Sepsis Management to Demonstrate the Value of the Lab
    When Good Biomarkers Go Bad: Effectively Utilizing Procalcitonin...
    DATE:  October 5, 2016 TIME:  10:00am PT, 1:00pm ET Sepsis, a host-mediated response to a systemic infection, is a leading cause of mortality worldwide (1).  Early recognit...
    Speaker: Joshua Hayden, PhD, DABCC, FACB
    Sponsored By: LabLeaders, LabLeaders
    7 1
    SEP 22, 2016 | 4:00 AM
    Cross-validation of Antibodies Using DigiWest
    Cross-validation of Antibodies Using DigiWest
    DATE: September 22, 2016 TIME:  4:00am PT, 7:00am ET, 11:00am GMT Here, we present a novel approach that combines the principles of the western blot (protein separation by SDS-PAGE; ...
    Speaker: Anthony Couvillon, PhD , Markus Templin, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    3 2
    SEP 20, 2016 | 7:00 AM
    Advanced Analysis of Complex Cell Models with the New Operetta CLS HCA System
    Advanced Analysis of Complex Cell Models with the New Operetta...
    DATE: September 20th, 2016TIME:  7:00AM PST, 10:00AM ETThere is a growing trend towards developing in vitro cell models that recapitulate the in vivo environment in basic research,...
    Speaker: Jacob Tesdorpf, PhD , Joe Trask
    Sponsored By: Revvity
    25
     
     
  • SEP 08, 2016 | 1:30 PM
    The Paradigm Shift in Clinical Microbiology
    The Paradigm Shift in Clinical Microbiology
    Multi-Drug Resistant Organisms (MDROs) are becoming a bigger and bigger concern throughout the world. Antibiotic resistance forms and spreads faster than pharmaceutical companies have been ab...
    Speaker: Steven Cagas, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    3
    AUG 30, 2016 | 8:00 AM
    Improved differentiation of human pluripotent stem cell-derived neurons through reduction of progenitor proliferation: impact on downstream applications
    Improved differentiation of human pluripotent stem cell-derived...
    Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
    Speaker: David Kuninger, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    1
    JUN 30, 2016 | 8:00 AM
    Surveying expression of immune checkpoint markers in the tissue microenvironment
    Surveying expression of immune checkpoint markers in the tissue...
    DATE:  June 30, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
    Speaker: Jeffrey Kim, PhD
    Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
    3 1
    JUN 30, 2016 | 7:30 AM
    Proteome centric precision medicine:  embracing pathological diversity
    Proteome centric precision medicine: embracing pathological diversity
    Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
    Speaker: Jennifer Van Eyk, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
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