Cancer diagnostics often begin with a biopsy and histopathologic examination, from the basis of physical examination and medical history. Sometimes the first indication is an abnormal laboratory test result (eg, anemia resulting from colon cancer).
A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
Personalised Healthcare is essential to AstraZeneca’s approach to drug development and is adopted by more than 80% of drug products in clinical development. Selection of the right patie...
The reproducibility of animal studies is now critical to ensure that limited resources are used wisely and that efforts yield useable knowledge. At this time, IACUCs and other similar a...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
DATE: January 26th, 2016
TIME: 8am pacific, 11am eastern
PTEN gene loss occurs frequently in castration-resistant prostate cancer (CRPC) and may drive progression through activation of th...
Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
Currently, next-generation sequencing is not only being used for basic discovery research but also in clinical settings for translational biomarker profiling and clinical research studies inc...
Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
This lecture will provide attendees with the knowledge and skills to bring on new clinical laboratory tests in clinical chemistry and molecular diagnostics. The lecture will provide a general...
Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
Detection of rare mutations is required for reliable identification of mutations in liquid biopsies and heterogeneous tumors. Yet low-level mutation detection remains a technically challengin...
The assessment of pigmented lesions is a difficult area of dermatology and dermatopathology. Melanoma is the leading cause of cancer in woman age 25-29 years, yet it is also a leading c...
Of special interest in a clinical setting is the identification and interpretation of somatic variants from the DNA of a tumor/normal matched pair. Studies have shown that a large proportion...
While TDM is routinely used in a number of medical fields, it has not gained wide utilization in oncology. There is a growing body of evidence demonstrating that current dosing methods based...
A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
DATE: September 9, 2015TIME: 9:00am PDT, 12:00PM EDTDriver mutations are causally implicated in tumorigenesis and disease progression, and they are defined by molecular abnormalities such as ...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Discussion of the guaiac based test introduced in 1971 and its' shortcomings versus Fecal Immunochemical Testing (FIT) and how it relates to acute and non-acute facilities.
Why is FIT...
Technological advances in high throughput, low cost DNA sequencing coupled with the availability of a high quality reference assembly allow us to interrogate the genome with greater precision...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
DATE: Tuesday, March 10, 2015 TIME: 09:00 PST, 11:00 CST, 12:00 EST, 16:00 GMTThe International Myeloma Working Group (IMWG) has issued updated criteria for the diagnosis of multiple...
Date: Tuesday, February 10th, 2015Time: 12:00PM PST, 3:00PM ESTFor the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology ...
A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
Personalised Healthcare is essential to AstraZeneca’s approach to drug development and is adopted by more than 80% of drug products in clinical development. Selection of the right patie...
The reproducibility of animal studies is now critical to ensure that limited resources are used wisely and that efforts yield useable knowledge. At this time, IACUCs and other similar a...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
DATE: January 26th, 2016
TIME: 8am pacific, 11am eastern
PTEN gene loss occurs frequently in castration-resistant prostate cancer (CRPC) and may drive progression through activation of th...
Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
Currently, next-generation sequencing is not only being used for basic discovery research but also in clinical settings for translational biomarker profiling and clinical research studies inc...
Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
This lecture will provide attendees with the knowledge and skills to bring on new clinical laboratory tests in clinical chemistry and molecular diagnostics. The lecture will provide a general...
Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
Detection of rare mutations is required for reliable identification of mutations in liquid biopsies and heterogeneous tumors. Yet low-level mutation detection remains a technically challengin...
The assessment of pigmented lesions is a difficult area of dermatology and dermatopathology. Melanoma is the leading cause of cancer in woman age 25-29 years, yet it is also a leading c...
Of special interest in a clinical setting is the identification and interpretation of somatic variants from the DNA of a tumor/normal matched pair. Studies have shown that a large proportion...
While TDM is routinely used in a number of medical fields, it has not gained wide utilization in oncology. There is a growing body of evidence demonstrating that current dosing methods based...
A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
DATE: September 9, 2015TIME: 9:00am PDT, 12:00PM EDTDriver mutations are causally implicated in tumorigenesis and disease progression, and they are defined by molecular abnormalities such as ...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Discussion of the guaiac based test introduced in 1971 and its' shortcomings versus Fecal Immunochemical Testing (FIT) and how it relates to acute and non-acute facilities.
Why is FIT...
Technological advances in high throughput, low cost DNA sequencing coupled with the availability of a high quality reference assembly allow us to interrogate the genome with greater precision...
Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
DATE: Tuesday, March 10, 2015 TIME: 09:00 PST, 11:00 CST, 12:00 EST, 16:00 GMTThe International Myeloma Working Group (IMWG) has issued updated criteria for the diagnosis of multiple...
Date: Tuesday, February 10th, 2015Time: 12:00PM PST, 3:00PM ESTFor the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology ...
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