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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • JUL 29, 2020 | 12:00 AM
      Automated Media Exchange for Long Term Spheroid Assays Using MultiFlo FX's new AMX Module
      Automated Media Exchange for Long Term Spheroid Assays Using MultiFlo...
      Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 22, 2020 | 10:00 AM
      Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
      Molecular Diagnostic Solutions in a Pandemic: Planning for the...
      DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
      Speaker: Heba Mostafa, MD, PhD, D(ABMM)
      Sponsored By: GenMark Dx
      27 13
      JUL 02, 2020 | 12:15 PM
      Authenticating human cells: Knowing exactly what is in your test tube
      Authenticating human cells: Knowing exactly what is in your test...
      The study of human development and diseases relies on analysis of samples obtained and manipulated ex vivo. It is critical in such studies to know the provenance and confirm that the identit...
      Speaker: Steve Jackson, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 17, 2020 | 10:30 AM
      Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19 Research
      Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19...
      COVID 19 has resulted in diverse research needs ranging from mechanism and impact of the disease, to solutions to identify, combat or treat the disease. Cellular technologies such as flow an...
      Speaker: Haley R. Pugsley, PhD , Kamala Tyagarajan, PhD
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 04, 2020 | 2:00 PM
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
      In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
      Speaker: KEYNOTE: Claire Brown, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      3
      JUN 03, 2020 | 1:00 PM
      Gene manipulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond
      Gene manipulation in primary human immune cells: Successful strategies...
      Gene manipulation studies in primary human immune cells can answer important biological questions within a clinically relevant cellular context. In this webinar we explore the use of several...
      Speaker: Verena Brucklacher-Waldert, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Horizon Discovery
      2
      JUN 02, 2020 | 9:00 AM
      Osmolality Testing: Providing Unique Process Control for Downstream Operations
      Osmolality Testing: Providing Unique Process Control for Downstream...
      DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
      Speaker: Alois Jungbauer, PhD , Kristeena Wright, PhD
      Sponsored By: Advanced Instruments
      11 1
      MAY 20, 2020 | 1:15 PM
      Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells & CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment...
      Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart®...
      Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
      Speaker: Jan Davidson, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 12:00 AM
      Gene-editing by a "click-of-a-button"
      Gene-editing by a "click-of-a-button"
      If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
      Speaker: Steve Shih, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
      Speaker: Joseph de Rutte
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      APR 29, 2020 | 6:00 AM
      Comprehensive cervical cancer screening by multiplexed HPV and biomarker mRNA detection using the Quantigene 2.0 platform
      Comprehensive cervical cancer screening by multiplexed HPV and...
      Background and aim: Multiplexing of biomarker panels by microsphere-based technologies are robust and cost-effective methods. The QuantiGene™ Plex Assay (ThermoFisher Scientific) platf...
      Speaker: Andreas Kaufmann, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 24, 2020 | 9:00 AM
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
      DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
      Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
      Sponsored By: Akoya Biosciences
      6
      APR 24, 2020 | 8:00 AM
      The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
      The International Council for Standardisation in Hematology (ICSH)...
      The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
      Speaker: Bob Gosselin
      Sponsored By: Diagnostica Stago, Inc.
      10
      APR 22, 2020 | 8:00 AM
      C.E. CREDITS
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      Discover strategies for labs to optimize coagulation testing, improve patient outcomes, and strengthen their role in clinical care teams....
      Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      7
      APR 21, 2020 | 12:00 PM
      SNVs to Large Structural Variation: Capturing nucleotide through inter-chromosomal variants through a powerful three-dimensional data type
      SNVs to Large Structural Variation: Capturing nucleotide through...
      Within the clinical arena, the oncology community has led the way in the early adoption of next generation sequencing. NGS is in widespread use in clinical cancer research and is now beginni...
      Speaker: Cory Padilla, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 20, 2020 | 8:00 AM
      C.E. CREDITS
      Emergency patient management using coagulation assays
      Emergency patient management using coagulation assays
      Explore emergency hemostasis testing approaches, from rapid lab assays to viscoelastic methods, for managing bleeding patients....
      Speaker: Wayne Chandler, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      17 5
      APR 15, 2020 | 4:00 PM
      From cell seeding to analysis - Getting the best out of your cell-based assay
      From cell seeding to analysis - Getting the best out of your cell-based...
      DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
      Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
      Sponsored By: Eppendorf, Promega
      19 2
      APR 08, 2020 | 12:00 AM
      Droplet Digital PCR as a tool for gene therapy application
      Droplet Digital PCR as a tool for gene therapy application
      Digital PCR has become the emerging technique for the sequence-specific detection and quantification of nucleic acids for various applications. During the recent years, numerous articles of...
      Speaker: Nagarjun Kasaraneni, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 07, 2020 | 8:00 AM
      Best Practice Criteria for Pluripotent Stem Cell Lines
      Best Practice Criteria for Pluripotent Stem Cell Lines
      DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
      Speaker: Lyn Healy
      Sponsored By: STEMCELL Technologies
      22
      MAR 24, 2020 | 11:00 AM
      3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic Neurons
      3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic...
      DATE: March 24, 2020 TIME: 11:00am PT, 2:00pm ET While in vitro cell culture has long been used to study neurological diseases, researchers have come to the realization that 2-D systems do n...
      Speaker: Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific - Disease Modeling
      9
      MAR 17, 2020 | 7:00 AM
      Time-Resolved STED Microscopy
      Time-Resolved STED Microscopy
      DATE: March 17, 2020 TIME: 7:00am PT, 10:00am ET Introduced more than 30 years ago, stimulated emission depletion (STED) microscopy has raised to a standard and widely used method for imagin...
      Speaker: Giuseppe Vicidomini, Ph.D.
      Sponsored By: Leica Microsystems
      8
      MAR 11, 2020 | 1:30 PM
      PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary Consortium Utilizing Human Single-Neuron Recordings
      PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary...
      Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
      Speaker: Adam Mamelak, MD , Ueli Rutishauser, PhD , Gabriel Kreiman, PhD , Jie Zheng, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
    JUL 29, 2020 | 12:00 AM
    Automated Media Exchange for Long Term Spheroid Assays Using MultiFlo FX's new AMX Module
    Automated Media Exchange for Long Term Spheroid Assays Using MultiFlo...
    Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
    JUL 02, 2020 | 12:15 PM
    Authenticating human cells: Knowing exactly what is in your test tube
    Authenticating human cells: Knowing exactly what is in your test...
    The study of human development and diseases relies on analysis of samples obtained and manipulated ex vivo. It is critical in such studies to know the provenance and confirm that the identit...
    Speaker: Steve Jackson, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 17, 2020 | 10:30 AM
    Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19 Research
    Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19...
    COVID 19 has resulted in diverse research needs ranging from mechanism and impact of the disease, to solutions to identify, combat or treat the disease. Cellular technologies such as flow an...
    Speaker: Haley R. Pugsley, PhD , Kamala Tyagarajan, PhD
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    1
     
     
  • JUN 04, 2020 | 2:00 PM
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
    In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
    Speaker: KEYNOTE: Claire Brown, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    3
    JUN 03, 2020 | 1:00 PM
    Gene manipulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond
    Gene manipulation in primary human immune cells: Successful strategies...
    Gene manipulation studies in primary human immune cells can answer important biological questions within a clinically relevant cellular context. In this webinar we explore the use of several...
    Speaker: Verena Brucklacher-Waldert, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    2
    JUN 02, 2020 | 9:00 AM
    Osmolality Testing: Providing Unique Process Control for Downstream Operations
    Osmolality Testing: Providing Unique Process Control for Downstream...
    DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
    Speaker: Alois Jungbauer, PhD , Kristeena Wright, PhD
    Sponsored By: Advanced Instruments
    11 1
    MAY 20, 2020 | 1:15 PM
    Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells & CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment...
    Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart®...
    Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
    Speaker: Jan Davidson, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 12:00 AM
    Gene-editing by a "click-of-a-button"
    Gene-editing by a "click-of-a-button"
    If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
    Speaker: Steve Shih, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 20, 2020 | 12:00 AM
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
    Speaker: Joseph de Rutte
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    APR 29, 2020 | 6:00 AM
    Comprehensive cervical cancer screening by multiplexed HPV and biomarker mRNA detection using the Quantigene 2.0 platform
    Comprehensive cervical cancer screening by multiplexed HPV and...
    Background and aim: Multiplexing of biomarker panels by microsphere-based technologies are robust and cost-effective methods. The QuantiGene™ Plex Assay (ThermoFisher Scientific) platf...
    Speaker: Andreas Kaufmann, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 24, 2020 | 9:00 AM
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
    DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
    Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
    Sponsored By: Akoya Biosciences
    6
    APR 24, 2020 | 8:00 AM
    The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
    The International Council for Standardisation in Hematology (ICSH)...
    The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
    Speaker: Bob Gosselin
    Sponsored By: Diagnostica Stago, Inc.
    10
     
     
  • APR 22, 2020 | 8:00 AM
    C.E. CREDITS
    The NEW Coag Value Playbook...Embrace the Power of Local Testing
    The NEW Coag Value Playbook...Embrace the Power of Local Testing
    Discover strategies for labs to optimize coagulation testing, improve patient outcomes, and strengthen their role in clinical care teams....
    Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    7
    APR 21, 2020 | 12:00 PM
    SNVs to Large Structural Variation: Capturing nucleotide through inter-chromosomal variants through a powerful three-dimensional data type
    SNVs to Large Structural Variation: Capturing nucleotide through...
    Within the clinical arena, the oncology community has led the way in the early adoption of next generation sequencing. NGS is in widespread use in clinical cancer research and is now beginni...
    Speaker: Cory Padilla, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 20, 2020 | 8:00 AM
    C.E. CREDITS
    Emergency patient management using coagulation assays
    Emergency patient management using coagulation assays
    Explore emergency hemostasis testing approaches, from rapid lab assays to viscoelastic methods, for managing bleeding patients....
    Speaker: Wayne Chandler, MD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    17 5
    APR 15, 2020 | 4:00 PM
    From cell seeding to analysis - Getting the best out of your cell-based assay
    From cell seeding to analysis - Getting the best out of your cell-based...
    DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
    Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
    Sponsored By: Eppendorf, Promega
    19 2
    APR 08, 2020 | 12:00 AM
    Droplet Digital PCR as a tool for gene therapy application
    Droplet Digital PCR as a tool for gene therapy application
    Digital PCR has become the emerging technique for the sequence-specific detection and quantification of nucleic acids for various applications. During the recent years, numerous articles of...
    Speaker: Nagarjun Kasaraneni, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1
     
     
  • APR 07, 2020 | 8:00 AM
    Best Practice Criteria for Pluripotent Stem Cell Lines
    Best Practice Criteria for Pluripotent Stem Cell Lines
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    Speaker: Lyn Healy
    Sponsored By: STEMCELL Technologies
    22
    MAR 24, 2020 | 11:00 AM
    3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic Neurons
    3-D Organoid Models for Differentiation of PSC-Derived Dopaminergic...
    DATE: March 24, 2020 TIME: 11:00am PT, 2:00pm ET While in vitro cell culture has long been used to study neurological diseases, researchers have come to the realization that 2-D systems do n...
    Speaker: Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific - Disease Modeling
    9
    MAR 17, 2020 | 7:00 AM
    Time-Resolved STED Microscopy
    Time-Resolved STED Microscopy
    DATE: March 17, 2020 TIME: 7:00am PT, 10:00am ET Introduced more than 30 years ago, stimulated emission depletion (STED) microscopy has raised to a standard and widely used method for imagin...
    Speaker: Giuseppe Vicidomini, Ph.D.
    Sponsored By: Leica Microsystems
    8
    MAR 11, 2020 | 1:30 PM
    PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary Consortium Utilizing Human Single-Neuron Recordings
    PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary...
    Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
    Speaker: Adam Mamelak, MD , Ueli Rutishauser, PhD , Gabriel Kreiman, PhD , Jie Zheng, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
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