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    Clinical Genetics

    Clinical Genetics is a diagnostic service and "genetic counseling" for individuals or families with conditions which may have a genetic basis.

    Webinars

    • SEP 30, 2020 | 12:00 AM
      Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
      Elucidation of remdesivir cytotoxicity pathways through genome-wide...
      The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
      Speaker: Minja Velimirovic, MSc, PhD Candidate
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
      Speaker: Adam Ameur
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 23, 2020 | 10:30 AM
      Practical Mass Cytometry
      Practical Mass Cytometry
      On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
      Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 23, 2020 | 9:00 AM
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
      Speaker: Benedetta Bussolati, MD, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
      SEP 23, 2020 | 7:30 AM
      Cell Culture Troubleshooting Tips and Tricks
      Cell Culture Troubleshooting Tips and Tricks
      Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
      Speaker: Marina Wiklander, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      6
      SEP 23, 2020 | 6:00 AM
      Welcome and Opening Remarks
      Welcome and Opening Remarks
      ...
      Speaker: Chris Linthwaite , Andrew Quong, PhD , Alex Cherkassky, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 22, 2020 | 11:00 AM
      A Novel Method for Quantitative  Western Blotting that Eliminates Errors from the Use of  Housekeeping Proteins
      A Novel Method for Quantitative Western Blotting that Eliminates...
      DATE: August 22, 2020 TIME: 9:00am PDT The western blotting technique that began as a means of detecting the protein of interest in a complex sample that may contain numerous other proteins...
      Speaker: Alok Tomar, PhD
      Sponsored By: Thermo Fisher Scientific
      11
      SEP 22, 2020 | 7:00 AM
      Cells in Motion - How to optimize your shake flask and bioreactor cultures
      Cells in Motion - How to optimize your shake flask and bioreactor...
      DATE: September 22, 2020 TIME: 7am PDT, 10am EDT, 4pm CEST Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells......
      Speaker: Ines Hartmann , Ankita Desai
      Sponsored By: Eppendorf
      17 2
      SEP 17, 2020 | 3:30 PM
      SARS-CoV-2 Testing Today and a New Serology Approach For High Throughput Screening
      SARS-CoV-2 Testing Today and a New Serology Approach For High...
      Richard Hughes: New immunogenicity strategies to meet the needs of a developing pandemic Shortly after the COVID-19 pandemic began, the subject of serological testing for anti-viral antibodi...
      Speaker: Russell Garlick, PhD , Richard Hughes , Joel Lefferts, PhD, HCLD, DABCC
      Presented at: Coronavirus Series
      Sponsored By: LGC Seracare
      1
      SEP 17, 2020 | 2:00 PM
      Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
      Keynote Presentation: The formation of an International Collaborative...
      Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
      Speaker: Jacqueline Fabius , Nevan Krogan, PhD
      Presented at: Coronavirus Series
      1
      SEP 17, 2020 | 11:00 AM
      Host and Viral Transcriptomes During COVID-19 Infection
      Host and Viral Transcriptomes During COVID-19 Infection
      In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
      Speaker: Christopher E. Mason, PhD
      Presented at: Coronavirus Series
      3
      SEP 17, 2020 | 9:00 AM
      Purification of cells from SARS-CoV-2 convalescent samples and potentially infectious materials with fluorescent-activated cell sorting
      Purification of cells from SARS-CoV-2 convalescent samples and...
      In recent months, we have seen a large part of the global scientific community shift to infectious disease research. In response, researchers are exploring safer and easier methods to handle...
      Speaker: Joe Ostrand, Ph.D.
      Presented at: Coronavirus Series
      Sponsored By: Miltenyi Biotec
      1
      SEP 17, 2020 | 9:00 AM
      Preclinical Optical Imaging of Infectious Diseases
      Preclinical Optical Imaging of Infectious Diseases
      PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
      Speaker: Kevin Francis, PhD
      Presented at: Coronavirus Series
      Sponsored By: PerkinElmer
      1
      SEP 16, 2020 | 6:00 AM
      A pandemic challenge - Implementing a COVID-19 Antibody test in record time!
      A pandemic challenge - Implementing a COVID-19 Antibody test in...
      Date: September 16, 2020 Time: 7:00am (PDT), 10:00am (EDT) During the early stages of the COVID-19 outbreak in the UK, there was a great deal of uncertainty. Pathology and diagnostic service...
      Speaker: Philip Craddock-Jones , Cecilia Scarponi
      Sponsored By: Ortho Clinical Diagnostics
      13 4
      SEP 11, 2020 | 8:00 AM
      Implementing a World-Class Clinical Pharmacogenomics Service
      Implementing a World-Class Clinical Pharmacogenomics Service
      DATE: September 11, 2020 TIME: 08:00am PT, 11:00pm ET This is the third topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. Pharmacog...
      Speaker: Dr. Hyun Kim
      Sponsored By: Thermo Fisher Scientific/Gibco
      8 2
      SEP 10, 2020 | 1:00 PM
      Keynote Presentation: Evolution of host-specific virulence in an RNA virus of Pacific salmonid fish
      Keynote Presentation: Evolution of host-specific virulence in...
      In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
      Speaker: Gael Kurath, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 PM
      Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
      Bacterial strain typing and genomics characterization of multi-drug...
      In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 10, 2020 | 10:00 AM
      Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
      Keynote Presentation: Squeezing out understanding from sequences:...
      Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
      Speaker: K. Eric Wommack
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 10:00 AM
      PGT-A simplified. Which of the leading NGS solutions is easiest to implement?
      PGT-A simplified. Which of the leading NGS solutions is easiest...
      DATE: September 10, 2020 TIME: 10:00am PT The vast majority of preimplantation genetic testing for aneuploidy (PGT-A) in the United States is performed using one of two NGS-based platforms,...
      Speaker: Adam Goodman
      Sponsored By: Thermo Fisher Scientific
      6
      SEP 10, 2020 | 12:00 AM
      Challenges in tracking horizontal gene transfer of antimicrobial resistance
      Challenges in tracking horizontal gene transfer of antimicrobial...
      Focusing on the urgent clinical problem of increasing carbapenem resistance in Enterobacteriaceae we have been evaluating detection methods in clinical microbiology and molecular transmissio...
      Speaker: Amy Mathers, MD, D(ABMM)
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 10, 2020 | 12:00 AM
      Insights into Aquatic Biofilm Dynamics by High-Throughput Identification of Bacterial Isolates and Full-Length 16S rRNA Gene Surveys
      Insights into Aquatic Biofilm Dynamics by High-Throughput Identification...
      Microbial biofilms form on all aquatic surfaces and can harbor pathogenic bacteria. In the aquaculture industry, Flavobacteria species can cause serious diseases and lead to high mortality....
      Speaker: Joerg Graf, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
      A novel strategy to investigate longitudinal changes within the...
      Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
      Speaker: Candice M. Brown, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Host responses to SARS-CoV-2
      Host responses to SARS-CoV-2
      The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
      Speaker: Angela L. Rasmussen, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      2
    SEP 30, 2020 | 12:00 AM
    Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
    Elucidation of remdesivir cytotoxicity pathways through genome-wide...
    The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
    Speaker: Minja Velimirovic, MSc, PhD Candidate
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
    Speaker: Adam Ameur
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 23, 2020 | 10:30 AM
    Practical Mass Cytometry
    Practical Mass Cytometry
    On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
    Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 23, 2020 | 9:00 AM
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
    Speaker: Benedetta Bussolati, MD, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    2
     
     
  • SEP 23, 2020 | 7:30 AM
    Cell Culture Troubleshooting Tips and Tricks
    Cell Culture Troubleshooting Tips and Tricks
    Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
    Speaker: Marina Wiklander, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    6
    SEP 23, 2020 | 6:00 AM
    Welcome and Opening Remarks
    Welcome and Opening Remarks
    ...
    Speaker: Chris Linthwaite , Andrew Quong, PhD , Alex Cherkassky, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 22, 2020 | 11:00 AM
    A Novel Method for Quantitative  Western Blotting that Eliminates Errors from the Use of  Housekeeping Proteins
    A Novel Method for Quantitative Western Blotting that Eliminates...
    DATE: August 22, 2020 TIME: 9:00am PDT The western blotting technique that began as a means of detecting the protein of interest in a complex sample that may contain numerous other proteins...
    Speaker: Alok Tomar, PhD
    Sponsored By: Thermo Fisher Scientific
    11
    SEP 22, 2020 | 7:00 AM
    Cells in Motion - How to optimize your shake flask and bioreactor cultures
    Cells in Motion - How to optimize your shake flask and bioreactor...
    DATE: September 22, 2020 TIME: 7am PDT, 10am EDT, 4pm CEST Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells......
    Speaker: Ines Hartmann , Ankita Desai
    Sponsored By: Eppendorf
    17 2
    SEP 17, 2020 | 3:30 PM
    SARS-CoV-2 Testing Today and a New Serology Approach For High Throughput Screening
    SARS-CoV-2 Testing Today and a New Serology Approach For High...
    Richard Hughes: New immunogenicity strategies to meet the needs of a developing pandemic Shortly after the COVID-19 pandemic began, the subject of serological testing for anti-viral antibodi...
    Speaker: Russell Garlick, PhD , Richard Hughes , Joel Lefferts, PhD, HCLD, DABCC
    Presented at: Coronavirus Series
    Sponsored By: LGC Seracare
    1
     
     
  • SEP 17, 2020 | 2:00 PM
    Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
    Keynote Presentation: The formation of an International Collaborative...
    Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
    Speaker: Jacqueline Fabius , Nevan Krogan, PhD
    Presented at: Coronavirus Series
    1
    SEP 17, 2020 | 11:00 AM
    Host and Viral Transcriptomes During COVID-19 Infection
    Host and Viral Transcriptomes During COVID-19 Infection
    In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
    Speaker: Christopher E. Mason, PhD
    Presented at: Coronavirus Series
    3
    SEP 17, 2020 | 9:00 AM
    Purification of cells from SARS-CoV-2 convalescent samples and potentially infectious materials with fluorescent-activated cell sorting
    Purification of cells from SARS-CoV-2 convalescent samples and...
    In recent months, we have seen a large part of the global scientific community shift to infectious disease research. In response, researchers are exploring safer and easier methods to handle...
    Speaker: Joe Ostrand, Ph.D.
    Presented at: Coronavirus Series
    Sponsored By: Miltenyi Biotec
    1
    SEP 17, 2020 | 9:00 AM
    Preclinical Optical Imaging of Infectious Diseases
    Preclinical Optical Imaging of Infectious Diseases
    PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
    Speaker: Kevin Francis, PhD
    Presented at: Coronavirus Series
    Sponsored By: PerkinElmer
    1
    SEP 16, 2020 | 6:00 AM
    A pandemic challenge - Implementing a COVID-19 Antibody test in record time!
    A pandemic challenge - Implementing a COVID-19 Antibody test in...
    Date: September 16, 2020 Time: 7:00am (PDT), 10:00am (EDT) During the early stages of the COVID-19 outbreak in the UK, there was a great deal of uncertainty. Pathology and diagnostic service...
    Speaker: Philip Craddock-Jones , Cecilia Scarponi
    Sponsored By: Ortho Clinical Diagnostics
    13 4
     
     
  • SEP 11, 2020 | 8:00 AM
    Implementing a World-Class Clinical Pharmacogenomics Service
    Implementing a World-Class Clinical Pharmacogenomics Service
    DATE: September 11, 2020 TIME: 08:00am PT, 11:00pm ET This is the third topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. Pharmacog...
    Speaker: Dr. Hyun Kim
    Sponsored By: Thermo Fisher Scientific/Gibco
    8 2
    SEP 10, 2020 | 1:00 PM
    Keynote Presentation: Evolution of host-specific virulence in an RNA virus of Pacific salmonid fish
    Keynote Presentation: Evolution of host-specific virulence in...
    In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
    Speaker: Gael Kurath, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 PM
    Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
    Bacterial strain typing and genomics characterization of multi-drug...
    In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    SEP 10, 2020 | 10:00 AM
    Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
    Keynote Presentation: Squeezing out understanding from sequences:...
    Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
    Speaker: K. Eric Wommack
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 10:00 AM
    PGT-A simplified. Which of the leading NGS solutions is easiest to implement?
    PGT-A simplified. Which of the leading NGS solutions is easiest...
    DATE: September 10, 2020 TIME: 10:00am PT The vast majority of preimplantation genetic testing for aneuploidy (PGT-A) in the United States is performed using one of two NGS-based platforms,...
    Speaker: Adam Goodman
    Sponsored By: Thermo Fisher Scientific
    6
     
     
  • SEP 10, 2020 | 12:00 AM
    Challenges in tracking horizontal gene transfer of antimicrobial resistance
    Challenges in tracking horizontal gene transfer of antimicrobial...
    Focusing on the urgent clinical problem of increasing carbapenem resistance in Enterobacteriaceae we have been evaluating detection methods in clinical microbiology and molecular transmissio...
    Speaker: Amy Mathers, MD, D(ABMM)
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 10, 2020 | 12:00 AM
    Insights into Aquatic Biofilm Dynamics by High-Throughput Identification of Bacterial Isolates and Full-Length 16S rRNA Gene Surveys
    Insights into Aquatic Biofilm Dynamics by High-Throughput Identification...
    Microbial biofilms form on all aquatic surfaces and can harbor pathogenic bacteria. In the aquaculture industry, Flavobacteria species can cause serious diseases and lead to high mortality....
    Speaker: Joerg Graf, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
    A novel strategy to investigate longitudinal changes within the...
    Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
    Speaker: Candice M. Brown, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    Host responses to SARS-CoV-2
    Host responses to SARS-CoV-2
    The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
    Speaker: Angela L. Rasmussen, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    2
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