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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Webinars

    • DEC 17, 2019 | 9:00 AM
      The role of SIRT1/LXR signaling in diabetic retinopathy
      The role of SIRT1/LXR signaling in diabetic retinopathy
      DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
      Speaker: Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      DEC 04, 2019 | 7:00 AM
      Improve your reproducibility - Liquid Handling is a crucial factor Exemplarily shown for NGS, ELISA and qPCR
      Improve your reproducibility - Liquid Handling is a crucial factor...
      DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
      Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa Gruschka
      Sponsored By: Eppendorf
      12
      NOV 21, 2019 | 9:00 AM
      The role of immune cells and immune checkpoints in multiple myeloma
      The role of immune cells and immune checkpoints in multiple myeloma
      DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
      Speaker: Nathalie Heider-Hönatsch, M.Sc.
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      NOV 18, 2019 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
      Speaker: Nadine Mellies, PhD , Katja Baesler, PhD
      Sponsored By: Eppendorf
      22 2
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      OCT 10, 2019 | 6:00 AM
      Highly-efficient and -specific genome editing with Cas9 nickase ribonucleoproteins in Primary T-cells
      Highly-efficient and -specific genome editing with Cas9 nickase...
      In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
      Speaker: Jacob Lamberth
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      1
      OCT 03, 2019 | 3:00 PM
      'Any Idiot can do it'.  How easy a knockout or knockin mouse could be generated using CRISPR/Cas9 gene editing technology?
      'Any Idiot can do it'. How easy a knockout or knockin mouse could...
      Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding the mechanisms of diseases. Using CRISPR/Cas9 we are able to p...
      Speaker: Gaetan Burgio, Msc, MBBS, MD, PhD
      Presented at: CRISPR Virtual Event Series 2019
      3
      OCT 03, 2019 | 1:30 PM
      Application of Genome Editing for Improving Banana with Disease Resistance
      Application of Genome Editing for Improving Banana with Disease...
      Banana (Musa spp.) is one of the major staple food crops grown in over 140 countries in the subtropics and tropics with annual global production of around 148 million metric, feeding about 50...
      Speaker: Leena Tripathi, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 1:30 PM
      Re-examining the ethical & regulatory dimensions of gene editing in the wake of the "CRISPR babies" scandal
      Re-examining the ethical & regulatory dimensions of gene editing...
      Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
      Speaker: Erika Kleiderman, B.Sc. , LL.B.
      Presented at: CRISPR Virtual Event Series 2019
      3
      OCT 03, 2019 | 12:00 PM
      Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
      Gene Editing Success: Considerations for maximizing your CRISPR...
      CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
      Speaker: Ryan Donnelly
      Presented at: CRISPR Virtual Event Series 2019
      Sponsored By: Horizon Discovery
      2
      OCT 03, 2019 | 10:30 AM
      Experimenting on future children: How do early adopters shape the ethics and regulation of new technologies?
      Experimenting on future children: How do early adopters shape...
      While CRISPR-Cas9 has dominated the science headlines in recent years, there has been a broad social and moral consensus that it is too soon to move to clinical use of genome editing in human...
      Speaker: Catherine Mills, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 9:00 AM
      Application of CRISPR-Cas9 in plants
      Application of CRISPR-Cas9 in plants
      CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
      Speaker: Xing-Liang Ma, PhD
      Presented at: CRISPR Virtual Event Series 2019
      2
      OCT 03, 2019 | 9:00 AM
      Structures of CRISPR-Cas surveillance complexes
      Structures of CRISPR-Cas surveillance complexes
      CRISPR (clustered regularly interspaced short palindromic repeats) RNA and CRISPR-associated genes (Cas) assemble into RNA-guided surveillance complex that targets foreign nucleic acids for d...
      Speaker: David Taylor, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 7:30 AM
      Keynote Presentation: CRISPR/Cas9 genome editing in mouse and rat: The PHENOMIN-ICS experience
      Keynote Presentation: CRISPR/Cas9 genome editing in mouse and...
      CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
      Speaker: Marie-Christine Birling, PhD
      Presented at: CRISPR Virtual Event Series 2019
      1
      OCT 03, 2019 | 6:00 AM
      CRISPR/Cas9 technology and insect population control
      CRISPR/Cas9 technology and insect population control
      Insects are the largest and most diverse arthropod group. Many insect species are agricultural pests or vectors of numerous diseases. In fact, the mosquito is the deadliest animal on the eart...
      Speaker: Nikolay Kandul, PhD
      Presented at: CRISPR Virtual Event Series 2019
      4
      OCT 03, 2019 | 6:00 AM
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
      Speaker: Lea Witkowsky, PhD
      Presented at: CRISPR Virtual Event Series 2019
      5
      SEP 05, 2019 | 7:00 AM
      The bread and butter method of genomics: How to improve your (q)PCR
      The bread and butter method of genomics: How to improve your (q)PCR
      DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
      Speaker: Tim Schommartz, PhD
      Sponsored By: Eppendorf
      17 1
      AUG 13, 2019 | 9:00 AM
      Nanometer-accuracy distance measurements between fluorophores at the single-molecule level
      Nanometer-accuracy distance measurements between fluorophores...
      DATE: August 13, 2019TIME: 9:00am PT, 12:00pm ET, 5:00pm BST Molecular complexes are major constituents of cells, hence unraveling their mechanisms is key to fuller comprehension of c...
      Speaker: Nico Stuurman, PhD , Marcin Barszczewski, PhD
      Sponsored By: Andor
      3
      JUN 19, 2019 | 11:00 AM
      Selecting the right tools to build your pluripotent stem cell based disease models
      Selecting the right tools to build your pluripotent stem cell...
      DATE: June 19, 2019TIME: 11:00am PDT, 2:00pm EDT Abstract:...
      Speaker: Erik Willems, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      JUN 19, 2019 | 10:00 AM
      Getting started in 3D:  Ask an Expert
      Getting started in 3D: Ask an Expert
      DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
      Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific
      6
      JUN 18, 2019 | 9:00 AM
      Hunting Exoplanets with the Next Generation Transit Survey (NGTS)
      Hunting Exoplanets with the Next Generation Transit Survey (NGTS)
      DATE: June 18, 2019TIME: 9:00am PDT, 12:00pm EDT, 5:00pm BST In the Atacama desert, Chile, twelve small aperture telescopes are observing the southern sky since 2016. Combining the opti...
      Speaker: Philipp Eigmüller, Dr. rer. nat., , Colin Coates, PhD
      Sponsored By: Andor
      5
      MAY 23, 2019 | 9:00 AM
      Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
      Doing More with Less: Stem Cells Regulate Their Fate by Altering...
      DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
      Speaker: Melika Sarem, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAY 21, 2019 | 7:00 AM
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
      DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
      Speaker: Eric Shifrut, PhD
      Sponsored By: Thermo Fisher Scientific
      10 1
      MAY 09, 2019 | 1:30 PM
      C.E. CREDITS
      The NIH Rare Disease Undiagnosed Diseases Network; Lessons Learnt and Challenges Faced in the First Four Years
      The NIH Rare Disease Undiagnosed Diseases Network; Lessons Learnt...
      In 2014, the Undiagnosed Diseases Network (UDN), which is funded by the NIH, was established as a network of seven clinical sites, two sequencing cores, and a coordinating center. Later, a ce...
      Speaker: Liz Worthey, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
    DEC 17, 2019 | 9:00 AM
    The role of SIRT1/LXR signaling in diabetic retinopathy
    The role of SIRT1/LXR signaling in diabetic retinopathy
    DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
    Speaker: Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    DEC 04, 2019 | 7:00 AM
    Improve your reproducibility - Liquid Handling is a crucial factor Exemplarily shown for NGS, ELISA and qPCR
    Improve your reproducibility - Liquid Handling is a crucial factor...
    DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
    Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa Gruschka
    Sponsored By: Eppendorf
    12
    NOV 21, 2019 | 9:00 AM
    The role of immune cells and immune checkpoints in multiple myeloma
    The role of immune cells and immune checkpoints in multiple myeloma
    DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
    Speaker: Nathalie Heider-Hönatsch, M.Sc.
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    NOV 18, 2019 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    Speaker: Nadine Mellies, PhD , Katja Baesler, PhD
    Sponsored By: Eppendorf
    22 2
    OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
     
     
  • OCT 10, 2019 | 6:00 AM
    Highly-efficient and -specific genome editing with Cas9 nickase ribonucleoproteins in Primary T-cells
    Highly-efficient and -specific genome editing with Cas9 nickase...
    In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
    Speaker: Jacob Lamberth
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    1
    OCT 03, 2019 | 3:00 PM
    'Any Idiot can do it'.  How easy a knockout or knockin mouse could be generated using CRISPR/Cas9 gene editing technology?
    'Any Idiot can do it'. How easy a knockout or knockin mouse could...
    Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding the mechanisms of diseases. Using CRISPR/Cas9 we are able to p...
    Speaker: Gaetan Burgio, Msc, MBBS, MD, PhD
    Presented at: CRISPR Virtual Event Series 2019
    3
    OCT 03, 2019 | 1:30 PM
    Application of Genome Editing for Improving Banana with Disease Resistance
    Application of Genome Editing for Improving Banana with Disease...
    Banana (Musa spp.) is one of the major staple food crops grown in over 140 countries in the subtropics and tropics with annual global production of around 148 million metric, feeding about 50...
    Speaker: Leena Tripathi, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 1:30 PM
    Re-examining the ethical & regulatory dimensions of gene editing in the wake of the "CRISPR babies" scandal
    Re-examining the ethical & regulatory dimensions of gene editing...
    Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
    Speaker: Erika Kleiderman, B.Sc. , LL.B.
    Presented at: CRISPR Virtual Event Series 2019
    3
    OCT 03, 2019 | 12:00 PM
    Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
    Gene Editing Success: Considerations for maximizing your CRISPR...
    CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
    Speaker: Ryan Donnelly
    Presented at: CRISPR Virtual Event Series 2019
    Sponsored By: Horizon Discovery
    2
     
     
  • OCT 03, 2019 | 10:30 AM
    Experimenting on future children: How do early adopters shape the ethics and regulation of new technologies?
    Experimenting on future children: How do early adopters shape...
    While CRISPR-Cas9 has dominated the science headlines in recent years, there has been a broad social and moral consensus that it is too soon to move to clinical use of genome editing in human...
    Speaker: Catherine Mills, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 9:00 AM
    Application of CRISPR-Cas9 in plants
    Application of CRISPR-Cas9 in plants
    CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
    Speaker: Xing-Liang Ma, PhD
    Presented at: CRISPR Virtual Event Series 2019
    2
    OCT 03, 2019 | 9:00 AM
    Structures of CRISPR-Cas surveillance complexes
    Structures of CRISPR-Cas surveillance complexes
    CRISPR (clustered regularly interspaced short palindromic repeats) RNA and CRISPR-associated genes (Cas) assemble into RNA-guided surveillance complex that targets foreign nucleic acids for d...
    Speaker: David Taylor, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 7:30 AM
    Keynote Presentation: CRISPR/Cas9 genome editing in mouse and rat: The PHENOMIN-ICS experience
    Keynote Presentation: CRISPR/Cas9 genome editing in mouse and...
    CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
    Speaker: Marie-Christine Birling, PhD
    Presented at: CRISPR Virtual Event Series 2019
    1
    OCT 03, 2019 | 6:00 AM
    CRISPR/Cas9 technology and insect population control
    CRISPR/Cas9 technology and insect population control
    Insects are the largest and most diverse arthropod group. Many insect species are agricultural pests or vectors of numerous diseases. In fact, the mosquito is the deadliest animal on the eart...
    Speaker: Nikolay Kandul, PhD
    Presented at: CRISPR Virtual Event Series 2019
    4
     
     
  • OCT 03, 2019 | 6:00 AM
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
    Speaker: Lea Witkowsky, PhD
    Presented at: CRISPR Virtual Event Series 2019
    5
    SEP 05, 2019 | 7:00 AM
    The bread and butter method of genomics: How to improve your (q)PCR
    The bread and butter method of genomics: How to improve your (q)PCR
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    Speaker: Tim Schommartz, PhD
    Sponsored By: Eppendorf
    17 1
    AUG 13, 2019 | 9:00 AM
    Nanometer-accuracy distance measurements between fluorophores at the single-molecule level
    Nanometer-accuracy distance measurements between fluorophores...
    DATE: August 13, 2019TIME: 9:00am PT, 12:00pm ET, 5:00pm BST Molecular complexes are major constituents of cells, hence unraveling their mechanisms is key to fuller comprehension of c...
    Speaker: Nico Stuurman, PhD , Marcin Barszczewski, PhD
    Sponsored By: Andor
    3
    JUN 19, 2019 | 11:00 AM
    Selecting the right tools to build your pluripotent stem cell based disease models
    Selecting the right tools to build your pluripotent stem cell...
    DATE: June 19, 2019TIME: 11:00am PDT, 2:00pm EDT Abstract:...
    Speaker: Erik Willems, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    JUN 19, 2019 | 10:00 AM
    Getting started in 3D:  Ask an Expert
    Getting started in 3D: Ask an Expert
    DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
    Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific
    6
     
     
  • JUN 18, 2019 | 9:00 AM
    Hunting Exoplanets with the Next Generation Transit Survey (NGTS)
    Hunting Exoplanets with the Next Generation Transit Survey (NGTS)
    DATE: June 18, 2019TIME: 9:00am PDT, 12:00pm EDT, 5:00pm BST In the Atacama desert, Chile, twelve small aperture telescopes are observing the southern sky since 2016. Combining the opti...
    Speaker: Philipp Eigmüller, Dr. rer. nat., , Colin Coates, PhD
    Sponsored By: Andor
    5
    MAY 23, 2019 | 9:00 AM
    Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
    Doing More with Less: Stem Cells Regulate Their Fate by Altering...
    DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
    Speaker: Melika Sarem, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
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    MAY 21, 2019 | 7:00 AM
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
    DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
    Speaker: Eric Shifrut, PhD
    Sponsored By: Thermo Fisher Scientific
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    MAY 09, 2019 | 1:30 PM
    C.E. CREDITS
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    Speaker: Liz Worthey, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
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