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    Directed Differentiation

    Directed differentiation: is a bioengineering methodology linking stem cell biology, developmental biology and tissue engineering. Directed differentiation harnesses the potential of stem cells by restraining their differentiation in vitro toward a specific cell type interest.

    Webinars

    • JUL 01, 2017 | 8:00 AM
      Directed differentiation of hematopoietic cells from human pluripotent stem cells
      Directed differentiation of hematopoietic cells from human pluripotent...
      The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
      Speaker: Alessandra Giorgetti
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUL 01, 2017 | 8:00 AM
      Building inner ear organoids from human pluripotent stem cells through directed self-assembly
      Building inner ear organoids from human pluripotent stem cells...
      The human inner ear contains ~75,000 sensory hair cells that detect sound or movement via mechanosensitive hair bundles and transmit signals to the brain via specialized sensory neurons. Inne...
      Speaker: Karl Koehler
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      JUN 26, 2017 | 8:00 AM
      WEBINAR: Finding pathologic T cells in rheumatoid arthritis by mass cytometry
      WEBINAR: Finding pathologic T cells in rheumatoid arthritis by...
      Unfortunately due to technical issues this webinar has been delayed until June 26th. If you are unable to make the new time, it will be available on demand for you to view.DATE: June 26,...
      Speaker: Deepak Rao, MD, PhD , Michelle Poulin, PhD
      Sponsored By: Standard BioTools
      7 1
      JUN 08, 2017 | 12:00 PM
      Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing the Latest Technologies from Thermo Fisher Scientific
      Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing...
      The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
      Speaker: Rhonda Newman, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      JUN 07, 2017 | 9:00 AM
      WEBINAR: Generation of purified human iPSC derived cardiomyocytes using clinically relevant workflow
      WEBINAR: Generation of purified human iPSC derived cardiomyocytes...
      DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
      Speaker: Todd Herron, BS, PhD
      Sponsored By: Miltenyi Biotec
      5 1
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
      MAY 01, 2017 | 8:00 AM
      Using iPSCs and Genome Engineering to Build Disease Models
      Using iPSCs and Genome Engineering to Build Disease Models
      Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
      Speaker: David Piper, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      MAR 16, 2017 | 1:30 PM
      Humans and fish to study the cellular mechanisms of neuromuscular development
      Humans and fish to study the cellular mechanisms of neuromuscular...
      Studying the genetics of rare congenital disorders disrupting cognitive function has led to the identification of multiple disease genes that helped us better understand the mechanisms underl...
      Speaker: Chiara Manzini, PhD
      Presented at: Neuroscience Virtual Event Series 2017
      1
      FEB 21, 2017 | 11:00 AM
      Genome Engineering to Introduce a Fluorescent Reporter into Human Pluripotent Stem Cells to Study Cardiac Disease
      Genome Engineering to Introduce a Fluorescent Reporter into Human...
      The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
      Speaker: Lise Munsie, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      NOV 17, 2016 | 7:00 AM
      From heart to mind: Simplified iPS cell reprogramming into cardiac and neural cells under hypoxic conditions
      From heart to mind: Simplified iPS cell reprogramming into cardiac...
      DATE: November 17, 2016 TIME: 7:00am PT, 10:00am ET Induced pluripotent stem (iPS) cell reprogramming allows turning an adult somatic cell into a pluripotent stem cell. Four Fac...
      Speaker: Rick Cohen, Ph.D
      Sponsored By: Eppendorf, Eppendorf
      5
      NOV 08, 2016 | 10:00 AM
      The genetics of aquaculture: Genotyping with GBS and arrays for species identification and trait improvement
      The genetics of aquaculture: Genotyping with GBS and arrays for...
      DATE: November 8, 2016 TIME: 10:00am PT, 1:00pm ET Stock and individual identification of Coho and Chinook Salmon in British Columbia via amplicon sequencing We have assemble...
      Speaker: Terry Beacham, PhD , Yniv Palti, PhD
      Sponsored By: Affymetrix, part of Thermo Fisher Scientific, Affymetrix, part of Thermo Fisher Scientific
      5 1
      OCT 18, 2016 | 11:45 AM
      Cell Models for Therapeutic Discovery - Leveraging Engineered, Primary and Stem Cells
      Cell Models for Therapeutic Discovery - Leveraging Engineered,...
      ...
      Speaker: David Piper, PhD
      Presented at: SyncD³ - Where drug discovery & development meet
      0
      AUG 30, 2016 | 8:00 AM
      From urine to the study of metabolic disease - A patient-driven strategy to decipher PCSK9 roles and functions.
      From urine to the study of metabolic disease - A patient-driven...
      In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
      Speaker: Karim Si-Tayeb, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      AUG 30, 2016 | 8:00 AM
      Human pluripotent stem cells for the study of enteric neuropathies
      Human pluripotent stem cells for the study of enteric neuropathies
      The human enteric nervous system (ENS) is derived from the neural crest and represents a complex network of ~500 million neurons with dozens of distinct neurotransmitter and hormone subtypes ...
      Speaker: Faranak Fattahi, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      AUG 30, 2016 | 8:00 AM
      iPSC Generation and Validation: Ensuring the best materials for downstream applications  iPSC Generation and Validation: Ensuring the best materials for downstream applications
      iPSC Generation and Validation: Ensuring the best materials for...
      The reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSC) has great potential of applications, not only in basic research, but also in drug screening and cell therapy. Wit...
      Speaker: Rene Quintanilla Jr.
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      0
      AUG 30, 2016 | 8:00 AM
      Tissue engineering with human pluripotent stem cells
      Tissue engineering with human pluripotent stem cells
      One of the ultimate goals in Regenerative Medicine is the generation of pluripotent stem cells (PSCs) directly from somatic cells obtained from patients. Although major findings in the defini...
      Speaker: Nuria Montserrat, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      AUG 30, 2016 | 8:00 AM
      Directed differentiation of induced pluripotent stem cells to hepatic stellate cells
      Directed differentiation of induced pluripotent stem cells to...
      In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
      Speaker: Pau Sancho Bru, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      OCT 28, 2015 | 11:00 AM
      The Hidden Effects of Epigenetic Discoveries
      The Hidden Effects of Epigenetic Discoveries
      DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
      Speaker: Jeffrey Kim, PhD , Christopher Scharer, PhD , Carlos Barrero, MD
      Sponsored By: Rockland
      25
      SEP 16, 2015 | 12:00 PM
      The Functionalization of C-H Bonds
      The Functionalization of C-H Bonds
      Among the frontier challenges in chemistry in the 21st century are the interconnected goals of increasing control of chemical reactivity while synthesizing and diversifying complex molecules ...
      Speaker: Christina White
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      MAY 13, 2015 | 10:30 AM
      Statistical methods for bulk and single-cell RNA-seq experiments
      Statistical methods for bulk and single-cell RNA-seq experiments
      I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
      Speaker: Christina Kendziorski, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4 1
      MAY 13, 2015 | 6:00 AM
      Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma
      Predictive Gene Signatures: Molecular Markers Distinguishing Colon...
      Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
      Speaker: Janice Drew, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      0
      APR 07, 2015 | 8:30 AM
      Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
      Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
      Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
      Speaker: Roberto Iacone, PhD , Brad Swanson, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      11 2
      DEC 09, 2014 | 7:00 AM
      Statin Myopathy: When might it be autoimmune?
      Statin Myopathy: When might it be autoimmune?
       Statins are among the most commonly prescribed medications that significantly reduce cardiovascular risk in selected individuals. However, these drugs can also be associated with muscle symp...
      Speaker: Lisa Christopher-Stine, MD
      Sponsored By: Inova Diagnostics, Inova Diagnostics
      28
      MAY 30, 2014 | 7:30 AM
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett and Jeoffrey Schageman
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      82
    JUL 01, 2017 | 8:00 AM
    Directed differentiation of hematopoietic cells from human pluripotent stem cells
    Directed differentiation of hematopoietic cells from human pluripotent...
    The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
    Speaker: Alessandra Giorgetti
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    JUL 01, 2017 | 8:00 AM
    Building inner ear organoids from human pluripotent stem cells through directed self-assembly
    Building inner ear organoids from human pluripotent stem cells...
    The human inner ear contains ~75,000 sensory hair cells that detect sound or movement via mechanosensitive hair bundles and transmit signals to the brain via specialized sensory neurons. Inne...
    Speaker: Karl Koehler
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    JUN 26, 2017 | 8:00 AM
    WEBINAR: Finding pathologic T cells in rheumatoid arthritis by mass cytometry
    WEBINAR: Finding pathologic T cells in rheumatoid arthritis by...
    Unfortunately due to technical issues this webinar has been delayed until June 26th. If you are unable to make the new time, it will be available on demand for you to view.DATE: June 26,...
    Speaker: Deepak Rao, MD, PhD , Michelle Poulin, PhD
    Sponsored By: Standard BioTools
    7 1
    JUN 08, 2017 | 12:00 PM
    Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing the Latest Technologies from Thermo Fisher Scientific
    Improved CRISPR Cas9 Editing of Pluripotent Stem Cells Utilizing...
    The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
    Speaker: Rhonda Newman, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    JUN 07, 2017 | 9:00 AM
    WEBINAR: Generation of purified human iPSC derived cardiomyocytes using clinically relevant workflow
    WEBINAR: Generation of purified human iPSC derived cardiomyocytes...
    DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
    Speaker: Todd Herron, BS, PhD
    Sponsored By: Miltenyi Biotec
    5 1
     
     
  • MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
    MAY 01, 2017 | 8:00 AM
    Using iPSCs and Genome Engineering to Build Disease Models
    Using iPSCs and Genome Engineering to Build Disease Models
    Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
    Speaker: David Piper, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    MAR 16, 2017 | 1:30 PM
    Humans and fish to study the cellular mechanisms of neuromuscular development
    Humans and fish to study the cellular mechanisms of neuromuscular...
    Studying the genetics of rare congenital disorders disrupting cognitive function has led to the identification of multiple disease genes that helped us better understand the mechanisms underl...
    Speaker: Chiara Manzini, PhD
    Presented at: Neuroscience Virtual Event Series 2017
    1
    FEB 21, 2017 | 11:00 AM
    Genome Engineering to Introduce a Fluorescent Reporter into Human Pluripotent Stem Cells to Study Cardiac Disease
    Genome Engineering to Introduce a Fluorescent Reporter into Human...
    The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
    Speaker: Lise Munsie, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
    NOV 17, 2016 | 7:00 AM
    From heart to mind: Simplified iPS cell reprogramming into cardiac and neural cells under hypoxic conditions
    From heart to mind: Simplified iPS cell reprogramming into cardiac...
    DATE: November 17, 2016 TIME: 7:00am PT, 10:00am ET Induced pluripotent stem (iPS) cell reprogramming allows turning an adult somatic cell into a pluripotent stem cell. Four Fac...
    Speaker: Rick Cohen, Ph.D
    Sponsored By: Eppendorf, Eppendorf
    5
     
     
  • NOV 08, 2016 | 10:00 AM
    The genetics of aquaculture: Genotyping with GBS and arrays for species identification and trait improvement
    The genetics of aquaculture: Genotyping with GBS and arrays for...
    DATE: November 8, 2016 TIME: 10:00am PT, 1:00pm ET Stock and individual identification of Coho and Chinook Salmon in British Columbia via amplicon sequencing We have assemble...
    Speaker: Terry Beacham, PhD , Yniv Palti, PhD
    Sponsored By: Affymetrix, part of Thermo Fisher Scientific, Affymetrix, part of Thermo Fisher Scientific
    5 1
    OCT 18, 2016 | 11:45 AM
    Cell Models for Therapeutic Discovery - Leveraging Engineered, Primary and Stem Cells
    Cell Models for Therapeutic Discovery - Leveraging Engineered,...
    ...
    Speaker: David Piper, PhD
    Presented at: SyncD³ - Where drug discovery & development meet
    0
    AUG 30, 2016 | 8:00 AM
    From urine to the study of metabolic disease - A patient-driven strategy to decipher PCSK9 roles and functions.
    From urine to the study of metabolic disease - A patient-driven...
    In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
    Speaker: Karim Si-Tayeb, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    AUG 30, 2016 | 8:00 AM
    Human pluripotent stem cells for the study of enteric neuropathies
    Human pluripotent stem cells for the study of enteric neuropathies
    The human enteric nervous system (ENS) is derived from the neural crest and represents a complex network of ~500 million neurons with dozens of distinct neurotransmitter and hormone subtypes ...
    Speaker: Faranak Fattahi, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    AUG 30, 2016 | 8:00 AM
    iPSC Generation and Validation: Ensuring the best materials for downstream applications  iPSC Generation and Validation: Ensuring the best materials for downstream applications
    iPSC Generation and Validation: Ensuring the best materials for...
    The reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSC) has great potential of applications, not only in basic research, but also in drug screening and cell therapy. Wit...
    Speaker: Rene Quintanilla Jr.
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    0
     
     
  • AUG 30, 2016 | 8:00 AM
    Tissue engineering with human pluripotent stem cells
    Tissue engineering with human pluripotent stem cells
    One of the ultimate goals in Regenerative Medicine is the generation of pluripotent stem cells (PSCs) directly from somatic cells obtained from patients. Although major findings in the defini...
    Speaker: Nuria Montserrat, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    AUG 30, 2016 | 8:00 AM
    Directed differentiation of induced pluripotent stem cells to hepatic stellate cells
    Directed differentiation of induced pluripotent stem cells to...
    In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
    Speaker: Pau Sancho Bru, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    OCT 28, 2015 | 11:00 AM
    The Hidden Effects of Epigenetic Discoveries
    The Hidden Effects of Epigenetic Discoveries
    DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
    Speaker: Jeffrey Kim, PhD , Christopher Scharer, PhD , Carlos Barrero, MD
    Sponsored By: Rockland
    25
    SEP 16, 2015 | 12:00 PM
    The Functionalization of C-H Bonds
    The Functionalization of C-H Bonds
    Among the frontier challenges in chemistry in the 21st century are the interconnected goals of increasing control of chemical reactivity while synthesizing and diversifying complex molecules ...
    Speaker: Christina White
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    MAY 13, 2015 | 10:30 AM
    Statistical methods for bulk and single-cell RNA-seq experiments
    Statistical methods for bulk and single-cell RNA-seq experiments
    I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
    Speaker: Christina Kendziorski, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4 1
     
     
  • MAY 13, 2015 | 6:00 AM
    Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma
    Predictive Gene Signatures: Molecular Markers Distinguishing Colon...
    Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
    Speaker: Janice Drew, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    0
    APR 07, 2015 | 8:30 AM
    Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
    Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
    Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
    Speaker: Roberto Iacone, PhD , Brad Swanson, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    11 2
    DEC 09, 2014 | 7:00 AM
    Statin Myopathy: When might it be autoimmune?
    Statin Myopathy: When might it be autoimmune?
     Statins are among the most commonly prescribed medications that significantly reduce cardiovascular risk in selected individuals. However, these drugs can also be associated with muscle symp...
    Speaker: Lisa Christopher-Stine, MD
    Sponsored By: Inova Diagnostics, Inova Diagnostics
    28
    MAY 30, 2014 | 7:30 AM
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett and Jeoffrey Schageman
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
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