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    Directed Differentiation

    Directed differentiation: is a bioengineering methodology linking stem cell biology, developmental biology and tissue engineering. Directed differentiation harnesses the potential of stem cells by restraining their differentiation in vitro toward a specific cell type interest.

    Webinars

    • JAN 30, 2020 | 9:00 AM
      An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
      An Automated Cancer Organoid Culture Platform to Accelerate Research...
      DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
      Speaker: Brooke Schuster
      Sponsored By: Thermo Fisher Scientific/Gibco
      10
      DEC 17, 2019 | 9:00 AM
      The role of SIRT1/LXR signaling in diabetic retinopathy
      The role of SIRT1/LXR signaling in diabetic retinopathy
      DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
      Speaker: Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      NOV 21, 2019 | 9:00 AM
      The role of immune cells and immune checkpoints in multiple myeloma
      The role of immune cells and immune checkpoints in multiple myeloma
      DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
      Speaker: Nathalie Heider-Hönatsch, M.Sc.
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      OCT 31, 2019 | 9:00 AM
      Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
      Investigation of Endothelial Cell Viability and Growth on 3D printed...
      DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
      Speaker: Chrisoula Chappell
      Sponsored By: Thermo Fisher Scientific/Gibco
      8
      SEP 24, 2019 | 10:00 AM
      CliniMACS Prodigy® Adherent Cell Culture System: Automated, large-scale, and GMP-compliant manufacturing of various stem cells and their derivatives
      CliniMACS Prodigy® Adherent Cell Culture System: Automated, large-scale,...
      DATE: September 24, 2019TIME: 10:00AM PDTRegenerative medicine has become a key focus worldwide and the number of stem cell-based clinical trials are rapidly increasing every year. Yet,...
      Speaker: Sebastian Knöbel, PhD , Dr. Chao Sheng
      Sponsored By: Miltenyi Biotec
      7
      JUN 19, 2019 | 8:00 AM
      Exploring the genetic landscape of solid tumors using whole-genome copy number analysis
      Exploring the genetic landscape of solid tumors using whole-genome...
      DATE: June 19, 2019TIME: 8:00am PDT, 11:00am EDT Approximately 80% of all cancers are known to be affected by both somatic mutations and copy number changes. Furthermore, r...
      Speaker: Ravindra Kolhe, MD, PhD , Joanna Przybyl, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      4
      MAR 27, 2019 | 12:00 PM
      Use of Gas Chromatography for the Analysis of Cannabinoids and Terpenes
      Use of Gas Chromatography for the Analysis of Cannabinoids and...
      With the legalization process currently taking place in the US, finding new techniques for the fast, cheap, and comprehensive analysis of Cannabis sativa components has become a major point o...
      Speaker: Allegra Leghissa, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      2
      MAR 26, 2019 | 10:00 AM
      TSH Receptor Antibodies: Nomenclature, Functionality and Assay Comparison
      TSH Receptor Antibodies: Nomenclature, Functionality and Assay...
      DATE:  March 26, 2019TIME:   10:00am PDT, 1:00pm EDT Despite being the most common autoimmune disorder in the United States, knowledge surrounding thyroid di...
      Speaker: George Kahaly, MD, PhD
      Sponsored By: Quidel
      7
      MAR 13, 2019 | 11:00 AM
      Neuroethics: From Lab to Law; Neuroscience in the Courtroom
      Neuroethics: From Lab to Law; Neuroscience in the Courtroom
      The implications of NIH BRAIN research stretch beyond traditional medical and research contexts. This LabRoots session will present recent developments at the intersection of neuroscience and...
      Speaker: Francis Shen, JD, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      1
      FEB 27, 2019 | 3:00 PM
      Do You Have the Gut-on-a-Chip?
      Do You Have the Gut-on-a-Chip?
      In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
      Speaker: Elena Naumovska, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      OCT 30, 2018 | 10:00 AM
      Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
      Post-translational Modifications and Data-Independent Acquisitions...
      DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
      Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
      Sponsored By: Cell Signaling Technology
      5
      SEP 27, 2018 | 1:30 PM
      Cilia Abnormalities and Developmental Defects in Lowe Syndrome
      Cilia Abnormalities and Developmental Defects in Lowe Syndrome
      Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
      Speaker: R. Claudio Aguilar, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      2
      MAY 03, 2018 | 11:00 AM
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
      DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
      Speaker: Sisi Li
      Sponsored By: Covaris
      5 2
      APR 24, 2018 | 8:00 AM
      KASP genotyping - better by design
      KASP genotyping - better by design
      DATE: April 24, 2018TIME: 8:00AM PSTIn this talk we will cover basic principles of KASP® genotyping chemistry and designing assays that are specific to desired targets. We will go o...
      Speaker: Jonathan Curry, PhD
      Sponsored By: LGC Seracare
      13
      MAR 22, 2018 | 10:30 AM
      Measuring Cortisol in Clinical Settings: Pitfalls, Challenges and Promises
      Measuring Cortisol in Clinical Settings: Pitfalls, Challenges...
      March 22, 2018 09:00AM PST, 1:30 pm EST Cortisol plays a central role in the diagnosis of adrenal excess/insufficiency and in theassessment of stress adaptation and relate...
      Speaker: LiSheng Chen, PhD, DABCC, FABC
      13 2
      MAR 14, 2018 | 6:00 AM
      Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's Walk into Computational Psychiatry
      Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's...
      Psychiatric diagnosis is inherently difficult, due to the lack of clear biomarkers or any other objective assessment. Although quantitative, the psychometric scales employed during the psychi...
      Speaker: Mauro Copelli, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      FEB 22, 2018 | 12:00 PM
      Commercializing Nanomedicine for Improving Human Health: Not Just Hype, It Is Really Happening!
      Commercializing Nanomedicine for Improving Human Health: Not Just...
      There is an acute shortage of organs due to disease, trauma, congenital defects, and most importantly, age related maladies. The synthetic materials used in tissue engineering applications to...
      Speaker: Thomas Webster, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      2
      NOV 09, 2017 | 12:00 PM
      On the road to realizing tissue engineering's transformative potential: multidisciplinary approach to accelerate bench-to-clinic transition
      On the road to realizing tissue engineering's transformative potential:...
      A panel of experts will discuss recent advances and current challenges for the successful development and application of human tissue for drug screening, tissue replacement and eventually org...
      Speaker: Nina Tandon , Benjamin Shepherd
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      OCT 24, 2017 | 7:00 AM
      WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known Disease Classifications of Prostate Cancer
      WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known...
      DATE: October, 24, 2017TIME:  7:00 AM PDT Metabolomics focuses on the chemical processes central to cellular metabolism. A robust mass spectrometry solution for screening...
      Speaker: Timothy Garrett, PhD
      Sponsored By: SCIEX
      4 1
      SEP 28, 2017 | 10:30 AM
      Engineering stem cell biology for disease modelling and therapeutics
      Engineering stem cell biology for disease modelling and therapeutics
      Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
      Speaker: Amr Abdeen, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 27, 2017 | 9:00 AM
      Regulation of actin during cell migration by nucleotide coding sequence and arginylation
      Regulation of actin during cell migration by nucleotide coding...
      Actin cytoskeleton drives cell migration in muscle and non-muscle cells and plays a major role in such diverse processes as tissue morphogenesis, muscle contraction, and cancer metastases. In...
      Speaker: Anna Kashina, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      JUL 25, 2017 | 9:00 AM
      WEBINAR: Functional Genomics and Drug Metabolism
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      7 1
      JUL 20, 2017 | 10:00 AM
      WEBINAR: Innovative quantitative imaging techniques and their utility in advancing neurobiology research
      WEBINAR: Innovative quantitative imaging techniques and their...
      DATE: July 20, 2017TIME: 10:00am PT, 1:00pm ETPart 1 - Daniel Beacham: Case study showing how CyQUANT Direct Cell Proliferation and Fluo-4 calcium imaging assays were us...
      Speaker: Dan Beacham, Ph.D. , Nicholas Radio Ph.D. , Michael Derr, M.S.
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      JUL 01, 2017 | 8:00 AM
      Custom-tailored cardiomyocytes: Directed differentiation of human pluripotent stem cells into defined atrial and ventricular cardiomyocyte subtypes
      Custom-tailored cardiomyocytes: Directed differentiation of human...
      Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
      Speaker: Lukas Cyganek
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
    JAN 30, 2020 | 9:00 AM
    An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
    An Automated Cancer Organoid Culture Platform to Accelerate Research...
    DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
    Speaker: Brooke Schuster
    Sponsored By: Thermo Fisher Scientific/Gibco
    10
    DEC 17, 2019 | 9:00 AM
    The role of SIRT1/LXR signaling in diabetic retinopathy
    The role of SIRT1/LXR signaling in diabetic retinopathy
    DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
    Speaker: Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    NOV 21, 2019 | 9:00 AM
    The role of immune cells and immune checkpoints in multiple myeloma
    The role of immune cells and immune checkpoints in multiple myeloma
    DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
    Speaker: Nathalie Heider-Hönatsch, M.Sc.
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    OCT 31, 2019 | 9:00 AM
    Investigation of Endothelial Cell Viability and Growth on 3D printed GelMa Vascular Networks
    Investigation of Endothelial Cell Viability and Growth on 3D printed...
    DATE: October 31, 2019TIME: 9:00am PDT, 12:00pm EDT INTRODUCTION: A major limitation for the development of 3D engineered tissues is the absence of viable and perfusable...
    Speaker: Chrisoula Chappell
    Sponsored By: Thermo Fisher Scientific/Gibco
    8
    SEP 24, 2019 | 10:00 AM
    CliniMACS Prodigy® Adherent Cell Culture System: Automated, large-scale, and GMP-compliant manufacturing of various stem cells and their derivatives
    CliniMACS Prodigy® Adherent Cell Culture System: Automated, large-scale,...
    DATE: September 24, 2019TIME: 10:00AM PDTRegenerative medicine has become a key focus worldwide and the number of stem cell-based clinical trials are rapidly increasing every year. Yet,...
    Speaker: Sebastian Knöbel, PhD , Dr. Chao Sheng
    Sponsored By: Miltenyi Biotec
    7
     
     
  • JUN 19, 2019 | 8:00 AM
    Exploring the genetic landscape of solid tumors using whole-genome copy number analysis
    Exploring the genetic landscape of solid tumors using whole-genome...
    DATE: June 19, 2019TIME: 8:00am PDT, 11:00am EDT Approximately 80% of all cancers are known to be affected by both somatic mutations and copy number changes. Furthermore, r...
    Speaker: Ravindra Kolhe, MD, PhD , Joanna Przybyl, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    4
    MAR 27, 2019 | 12:00 PM
    Use of Gas Chromatography for the Analysis of Cannabinoids and Terpenes
    Use of Gas Chromatography for the Analysis of Cannabinoids and...
    With the legalization process currently taking place in the US, finding new techniques for the fast, cheap, and comprehensive analysis of Cannabis sativa components has become a major point o...
    Speaker: Allegra Leghissa, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    2
    MAR 26, 2019 | 10:00 AM
    TSH Receptor Antibodies: Nomenclature, Functionality and Assay Comparison
    TSH Receptor Antibodies: Nomenclature, Functionality and Assay...
    DATE:  March 26, 2019TIME:   10:00am PDT, 1:00pm EDT Despite being the most common autoimmune disorder in the United States, knowledge surrounding thyroid di...
    Speaker: George Kahaly, MD, PhD
    Sponsored By: Quidel
    7
    MAR 13, 2019 | 11:00 AM
    Neuroethics: From Lab to Law; Neuroscience in the Courtroom
    Neuroethics: From Lab to Law; Neuroscience in the Courtroom
    The implications of NIH BRAIN research stretch beyond traditional medical and research contexts. This LabRoots session will present recent developments at the intersection of neuroscience and...
    Speaker: Francis Shen, JD, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    1
    FEB 27, 2019 | 3:00 PM
    Do You Have the Gut-on-a-Chip?
    Do You Have the Gut-on-a-Chip?
    In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
    Speaker: Elena Naumovska, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
     
     
  • OCT 30, 2018 | 10:00 AM
    Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
    Post-translational Modifications and Data-Independent Acquisitions...
    DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
    Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
    Sponsored By: Cell Signaling Technology
    5
    SEP 27, 2018 | 1:30 PM
    Cilia Abnormalities and Developmental Defects in Lowe Syndrome
    Cilia Abnormalities and Developmental Defects in Lowe Syndrome
    Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
    Speaker: R. Claudio Aguilar, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    2
    MAY 03, 2018 | 11:00 AM
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    Speaker: Sisi Li
    Sponsored By: Covaris
    5 2
    APR 24, 2018 | 8:00 AM
    KASP genotyping - better by design
    KASP genotyping - better by design
    DATE: April 24, 2018TIME: 8:00AM PSTIn this talk we will cover basic principles of KASP® genotyping chemistry and designing assays that are specific to desired targets. We will go o...
    Speaker: Jonathan Curry, PhD
    Sponsored By: LGC Seracare
    13
    MAR 22, 2018 | 10:30 AM
    Measuring Cortisol in Clinical Settings: Pitfalls, Challenges and Promises
    Measuring Cortisol in Clinical Settings: Pitfalls, Challenges...
    March 22, 2018 09:00AM PST, 1:30 pm EST Cortisol plays a central role in the diagnosis of adrenal excess/insufficiency and in theassessment of stress adaptation and relate...
    Speaker: LiSheng Chen, PhD, DABCC, FABC
    13 2
     
     
  • MAR 14, 2018 | 6:00 AM
    Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's Walk into Computational Psychiatry
    Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's...
    Psychiatric diagnosis is inherently difficult, due to the lack of clear biomarkers or any other objective assessment. Although quantitative, the psychometric scales employed during the psychi...
    Speaker: Mauro Copelli, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    FEB 22, 2018 | 12:00 PM
    Commercializing Nanomedicine for Improving Human Health: Not Just Hype, It Is Really Happening!
    Commercializing Nanomedicine for Improving Human Health: Not Just...
    There is an acute shortage of organs due to disease, trauma, congenital defects, and most importantly, age related maladies. The synthetic materials used in tissue engineering applications to...
    Speaker: Thomas Webster, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    2
    NOV 09, 2017 | 12:00 PM
    On the road to realizing tissue engineering's transformative potential: multidisciplinary approach to accelerate bench-to-clinic transition
    On the road to realizing tissue engineering's transformative potential:...
    A panel of experts will discuss recent advances and current challenges for the successful development and application of human tissue for drug screening, tissue replacement and eventually org...
    Speaker: Nina Tandon , Benjamin Shepherd
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    OCT 24, 2017 | 7:00 AM
    WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known Disease Classifications of Prostate Cancer
    WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known...
    DATE: October, 24, 2017TIME:  7:00 AM PDT Metabolomics focuses on the chemical processes central to cellular metabolism. A robust mass spectrometry solution for screening...
    Speaker: Timothy Garrett, PhD
    Sponsored By: SCIEX
    4 1
    SEP 28, 2017 | 10:30 AM
    Engineering stem cell biology for disease modelling and therapeutics
    Engineering stem cell biology for disease modelling and therapeutics
    Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
    Speaker: Amr Abdeen, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
     
     
  • SEP 27, 2017 | 9:00 AM
    Regulation of actin during cell migration by nucleotide coding sequence and arginylation
    Regulation of actin during cell migration by nucleotide coding...
    Actin cytoskeleton drives cell migration in muscle and non-muscle cells and plays a major role in such diverse processes as tissue morphogenesis, muscle contraction, and cancer metastases. In...
    Speaker: Anna Kashina, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    JUL 25, 2017 | 9:00 AM
    WEBINAR: Functional Genomics and Drug Metabolism
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
    7 1
    JUL 20, 2017 | 10:00 AM
    WEBINAR: Innovative quantitative imaging techniques and their utility in advancing neurobiology research
    WEBINAR: Innovative quantitative imaging techniques and their...
    DATE: July 20, 2017TIME: 10:00am PT, 1:00pm ETPart 1 - Daniel Beacham: Case study showing how CyQUANT Direct Cell Proliferation and Fluo-4 calcium imaging assays were us...
    Speaker: Dan Beacham, Ph.D. , Nicholas Radio Ph.D. , Michael Derr, M.S.
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    JUL 01, 2017 | 8:00 AM
    Custom-tailored cardiomyocytes: Directed differentiation of human pluripotent stem cells into defined atrial and ventricular cardiomyocyte subtypes
    Custom-tailored cardiomyocytes: Directed differentiation of human...
    Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
    Speaker: Lukas Cyganek
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
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