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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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APR 14, 2017Cell & Molecular Biology
Researchers have used a grafting technique plus a reagent that is approved for use in humans to enable blind zebrafish t ...Written By: Carmen LeitchAPR 14, 2017Chemistry & Physics
Initial Demonstrations Yield Compounds with Promise for Treating COPD, Cystic Fibrosis and Other Lung Disorders Co-autho ...Written By: The Scripps Research Institute (TSRI)APR 12, 2017Microbiology
I just got a postcard in the mail from my veterinarian. They say it’s time for my dog to get her rabies vaccinatio ...Written By: Kerry EvansAPR 12, 2017Neuroscience
LA JOLLA, CA – April 12, 2017 – A new study led by scientists at The Scripps Research Institute (TSRI) could ...Written By: The Scripps Research Institute (TSRI)APR 10, 2017Cell & Molecular Biology
TSRI and City of Hope Team Up in Effort to Cure AIDS LA JOLLA, CA – April 10, 2017 – Scientists at The Scrip ...Written By: The Scripps Research Institute (TSRI)APR 07, 2017Cell & Molecular Biology
Stem cells have incredible potential; in the pluripotent state, they are able to develop into any type of cell in the bo ...Written By: Carmen LeitchMAR 24, 2017Clinical & Molecular DX
Beyond vanity gains, a drug that slows down the ageing process could be transformative for people who suffer from aging- ...MAR 21, 2017Immunology
The same immune process that protects the immune system from friendly fire by soothing inflammatory reactions and reduci ...Written By: Kara MarkerMAR 19, 2017Immunology
There is an new connection between obesity and hypertension, between the cardiovascular system and the immune response: ...Written By: Kara MarkerMAR 14, 2017Microbiology
Researchers may have made a breakthrough in the fight against a variety of diseases that are difficult to treat. They ca ...Written By: Carmen LeitchMAR 14, 2017Cancer
A drug, Cabozantinib, has demonstrated efficacy against invasive prostate cancer in mice.Written By: Carmen LeitchMAR 10, 2017Cardiology
A careful balance must be struck between various pathways in the body, or adverse cardiac events like heart attac ...Written By: Kara MarkerFEB 27, 2017Immunology
Thanks to the innate immune response, humans have an immediately-acting defense mechanism set in place against invading ...Written By: Kara MarkerFEB 20, 2017Cell & Molecular Biology
A new molecule has been found and it could help in the development of new antibiotics – a major priority for publi ...Written By: Carmen LeitchFEB 20, 2017Cancer
Researchers have captured how a new organo-metal compound infiltrates cancer cells and destroys its most vulnerable orga ...FEB 07, 2017Cell & Molecular Biology
A new antibiotic, teixobactin, was identified a few years ago. It can kill bacteria and has not been shown resistance by ...Written By: Carmen LeitchFEB 03, 2017Cancer
Scientists on the quest to offer more hope for glioblastoma patients may have found a way to stop the growth of the dead ...JAN 29, 2017Cell & Molecular Biology
Artificial intelligence has helped researchers learn more about the biophysics of cancer. Research teams that worked in ...Written By: Carmen LeitchJAN 23, 2017Genetics & Genomics
LA JOLLA, CA – January 23, 2017 – Life’s genetic code has only ever contained four natural bases. Thes ...Written By: The Scripps Research Institute (TSRI)JAN 22, 2017Immunology
New technology allows scientists to watch immune cells move in real time, and researchers recently took advantage of thi ...Written By: Kara MarkerJAN 19, 2017Clinical & Molecular DX
LA JOLLA, CA – January 19, 2017 – A team led by scientists at The Scripps Research Institute (TSRI) has deve ...Written By: The Scripps Research Institute (TSRI)JAN 14, 2017Cell & Molecular Biology
Scientists are always striving to know more about the physiology of exercise, especially as health conditions related to ...Written By: Carmen LeitchJAN 11, 2017Cell & Molecular Biology
In the following video from the Francis Crick Institute, you can get a look at why cancer cells are able to proliferate ...Written By: Carmen LeitchJAN 04, 2017Cell & Molecular Biology
JUPITER, FL – January 4, 2017 – Scientists on the Florida campus of The Scripps Research Institute (TSRI) ha ...Written By: The Scripps Research Institute (TSRI)
APR 14, 2017
Cell & Molecular Biology
Researchers have used a grafting technique plus a reagent that is approved for use in humans to enable blind zebrafish t
...
Written By:
Carmen Leitch
APR 14, 2017
Chemistry & Physics
Initial Demonstrations Yield Compounds with Promise for Treating COPD, Cystic Fibrosis and Other Lung Disorders Co-autho
...
Written By:
The Scripps Research Institute (TSRI)
APR 12, 2017
Microbiology
I just got a postcard in the mail from my veterinarian. They say it’s time for my dog to get her rabies vaccinatio
...
Written By:
Kerry Evans
APR 12, 2017
Neuroscience
LA JOLLA, CA – April 12, 2017 – A new study led by scientists at The Scripps Research Institute (TSRI) could
...
Written By:
The Scripps Research Institute (TSRI)
APR 10, 2017
Cell & Molecular Biology
TSRI and City of Hope Team Up in Effort to Cure AIDS LA JOLLA, CA – April 10, 2017 – Scientists at The Scrip
...
Written By:
The Scripps Research Institute (TSRI)
APR 07, 2017
Cell & Molecular Biology
Stem cells have incredible potential; in the pluripotent state, they are able to develop into any type of cell in the bo
...
Written By:
Carmen Leitch
MAR 24, 2017
Clinical & Molecular DX
Beyond vanity gains, a drug that slows down the ageing process could be transformative for people who suffer from aging-
...
MAR 21, 2017
Immunology
The same immune process that protects the immune system from friendly fire by soothing inflammatory reactions and reduci
...
Written By:
Kara Marker
MAR 19, 2017
Immunology
There is an new connection between obesity and hypertension, between the cardiovascular system and the immune response:
...
Written By:
Kara Marker
MAR 14, 2017
Microbiology
Researchers may have made a breakthrough in the fight against a variety of diseases that are difficult to treat. They ca
...
Written By:
Carmen Leitch
MAR 14, 2017
Cancer
A drug, Cabozantinib, has demonstrated efficacy against invasive prostate cancer in mice.
Written By:
Carmen Leitch
MAR 10, 2017
Cardiology
A careful balance must be struck between various pathways in the body, or adverse cardiac events like heart attac
...
Written By:
Kara Marker
FEB 27, 2017
Immunology
Thanks to the innate immune response, humans have an immediately-acting defense mechanism set in place against invading
...
Written By:
Kara Marker
FEB 20, 2017
Cell & Molecular Biology
A new molecule has been found and it could help in the development of new antibiotics – a major priority for publi
...
Written By:
Carmen Leitch
FEB 20, 2017
Cancer
Researchers have captured how a new organo-metal compound infiltrates cancer cells and destroys its most vulnerable orga
...
FEB 07, 2017
Cell & Molecular Biology
A new antibiotic, teixobactin, was identified a few years ago. It can kill bacteria and has not been shown resistance by
...
Written By:
Carmen Leitch
FEB 03, 2017
Cancer
Scientists on the quest to offer more hope for glioblastoma patients may have found a way to stop the growth of the dead
...
JAN 29, 2017
Cell & Molecular Biology
Artificial intelligence has helped researchers learn more about the biophysics of cancer. Research teams that worked in
...
Written By:
Carmen Leitch
JAN 23, 2017
Genetics & Genomics
LA JOLLA, CA – January 23, 2017 – Life’s genetic code has only ever contained four natural bases. Thes
...
Written By:
The Scripps Research Institute (TSRI)
JAN 22, 2017
Immunology
New technology allows scientists to watch immune cells move in real time, and researchers recently took advantage of thi
...
Written By:
Kara Marker
JAN 19, 2017
Clinical & Molecular DX
LA JOLLA, CA – January 19, 2017 – A team led by scientists at The Scripps Research Institute (TSRI) has deve
...
Written By:
The Scripps Research Institute (TSRI)
JAN 14, 2017
Cell & Molecular Biology
Scientists are always striving to know more about the physiology of exercise, especially as health conditions related to
...
Written By:
Carmen Leitch
JAN 11, 2017
Cell & Molecular Biology
In the following video from the Francis Crick Institute, you can get a look at why cancer cells are able to proliferate
...
Written By:
Carmen Leitch
JAN 04, 2017
Cell & Molecular Biology
JUPITER, FL – January 4, 2017 – Scientists on the Florida campus of The Scripps Research Institute (TSRI) ha
...
Written By:
The Scripps Research Institute (TSRI)