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    Gene Sequencing

    Gene Sequencing: the process of determining the precise order of nucleotides within a DNA molecule. It includes any method or technology that is used to determine the order of the four bases-adenine, guanine, cytosine, and thymine-in a strand of DNA. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery.

    Webinars

    • FEB 05, 2014 | 9:00 AM
      Going Back to Nature: The Benefits of Wood Enrichment
      Going Back to Nature: The Benefits of Wood Enrichment
      Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
      Speaker: Karen Froberg-Fejko, LATg, VMD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 9:00 AM
      The Manager of the Vivarium at the End of the World
      The Manager of the Vivarium at the End of the World
      The city of Valdivia is located in Chile, South America, 841 km south of its capital city Santiago. I moved to Valdivia early in 2004 to participate in the development of a new animal facilit...
      Speaker: Juan Manuel Baamonde
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 05, 2014 | 9:00 AM
      What Germs? Hiring and Training Gnotobiotic Technicians
      What Germs? Hiring and Training Gnotobiotic Technicians
      The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
      Speaker: Michelle Hull, MS RLATg
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      3
      FEB 05, 2014 | 9:00 AM
      Challenges in Enriching Animal Environments in a Contract Research Organization
      Challenges in Enriching Animal Environments in a Contract Research...
      Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
      Speaker: Michelle Weideman, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      4
      FEB 05, 2014 | 9:00 AM
      C.E. CREDITS
      Certifying competence
      Certifying competence
      Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
      Speaker: Bryan R Howard, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      42
      FEB 05, 2014 | 8:00 AM
      The 8th Edition of the Guide: An Environmental Impact
      The 8th Edition of the Guide: An Environmental Impact
      The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
      Speaker: John Bradfield, PhD, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 05, 2014 | 7:00 AM
      C.E. CREDITS
      Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs
      Simplifying Rodent Surgery... Tips for improving technique without...
      Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      47
      FEB 05, 2014 | 6:00 AM
      C.E. CREDITS
      Bedding vs. Thermoregulation
      Bedding vs. Thermoregulation
      This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
      Speaker: Andrea Gay
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      28 1
      NOV 20, 2013 | 11:00 AM
      Tools to accelerate biomarker screening for CDx
      Tools to accelerate biomarker screening for CDx
      ...
      Speaker: Dan Rhodes, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      199
      NOV 08, 2013 | 12:00 PM
      Childhood cancer with various genomic assay including whole genome sequencing
      Childhood cancer with various genomic assay including whole genome...
      The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
      Speaker: Jaime Guidry Auvil, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      4
      OCT 17, 2013 | 9:00 AM
      Using DNASTAR Software to Identify Cancer Variations in Targeted Resequencing Data
      Using DNASTAR Software to Identify Cancer Variations in Targeted...
      DNASTAR offers an integrated suite of software for assembling and analyzing data from all major next-generation sequencing platforms. The software supports a variety of reference guided and d...
      Speaker: Matthew Keyser, MS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      48
      OCT 17, 2013 | 6:00 AM
      A Bioinformatics Approach to Clinical Sequencing
      A Bioinformatics Approach to Clinical Sequencing
      The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
      Speaker: Dan Rhodes, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
      Resistance to AR Signaling Inhibitors in Castration Resistant...
      While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
      Speaker: Elahe A Mostaghel, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      68
      OCT 16, 2013 | 9:00 AM
      C.E. CREDITS
      Keynote: Breast Cancer Genomics and Genetics
      Keynote: Breast Cancer Genomics and Genetics
      It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
      Speaker: Charles M. Perou, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      132
      OCT 16, 2013 | 6:00 AM
      Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium development of a tool for clinical research applications
      Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium...
      The knowledge of molecular alterations involved in colon carcinoma (CRC) and non-small-cell lung carcinoma (NSCLC) has significantly increased in the past few years. Molecular subgroups of t...
      Speaker: Nicola Normanno, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      102
      AUG 22, 2013 | 4:00 PM
      C.E. CREDITS
      Complexity of Mammalian Transcription
      Complexity of Mammalian Transcription
      The next generation sequencing technologies are profoundly influencing our way to study biology. We have previously developed cap-analysis gene expression (CAGE) to simultaneously mRNA/noncod...
      Speaker: Piero Carninci, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      50
      AUG 22, 2013 | 3:00 PM
      C.E. CREDITS
      Evaluation challenges and regulatory considerations for next-generation sequencing and other high throughput genomic technology based clinical applications
      Evaluation challenges and regulatory considerations for next-generation...
      The use of ultrahigh throughput diagnostic tests that determine genetic sequence variation to guide patient care is rapidly expanding, fueled by the enormous growth in sequencing platform dev...
      Speaker: Živana Težak, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      282
      AUG 22, 2013 | 2:00 PM
      The Road to Genomic Medicine is Paved with Data and Information
      The Road to Genomic Medicine is Paved with Data and Information
      Since the introduction of second-generation DNS sequencing technologies in 2007, the cost of genome sequencing has been consistently by 33% per quarter, with the $1000 genome arriving in 2012...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      110
      AUG 22, 2013 | 1:00 PM
      Dominant regulation of gene expression by microRNAs
      Dominant regulation of gene expression by microRNAs
      MicroRNAs are short non-coding cellular regulators of gene expression. Each microRNA controls the expression of a large set of genes, and microRNAs collectively, may regulate more than half o...
      Speaker: Noam Shomron, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      121
      AUG 22, 2013 | 12:00 PM
      C.E. CREDITS
      Exome Sequencing as a Diagnostic Tool
      Exome Sequencing as a Diagnostic Tool
      It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
      Speaker: Pinar Bayrak-Toydemir, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      66
      AUG 22, 2013 | 10:00 AM
      C.E. CREDITS
      Using Prostate Cancer Exome Data to Identify Candidate Genes
      Using Prostate Cancer Exome Data to Identify Candidate Genes
      In this presentation, exome data from individuals with prostate cancer will be aligned against an annotated reference human genome and SNPs will be identified using DNASTARs SeqMan NGen softw...
      Speaker: Matthew Keyser, MS
      Presented at: Genetics and Genomics Virtual Event Series 2013
      60
      AUG 22, 2013 | 10:00 AM
      C.E. CREDITS
      Clinical Interpretation of Sequence Variants
      Clinical Interpretation of Sequence Variants
      The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
      Speaker: Elaine Lyon, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      72
      AUG 22, 2013 | 9:00 AM
      Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
      Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
      The rapid advancements in next generation sequencing have served the research market very well, delivering more and more sequence for less and less money. While these advancements are still b...
      Speaker: Shawn Baker, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      222
    FEB 05, 2014 | 9:00 AM
    Going Back to Nature: The Benefits of Wood Enrichment
    Going Back to Nature: The Benefits of Wood Enrichment
    Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
    Speaker: Karen Froberg-Fejko, LATg, VMD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 9:00 AM
    The Manager of the Vivarium at the End of the World
    The Manager of the Vivarium at the End of the World
    The city of Valdivia is located in Chile, South America, 841 km south of its capital city Santiago. I moved to Valdivia early in 2004 to participate in the development of a new animal facilit...
    Speaker: Juan Manuel Baamonde
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 05, 2014 | 9:00 AM
    What Germs? Hiring and Training Gnotobiotic Technicians
    What Germs? Hiring and Training Gnotobiotic Technicians
    The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
    Speaker: Michelle Hull, MS RLATg
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    3
    FEB 05, 2014 | 9:00 AM
    Challenges in Enriching Animal Environments in a Contract Research Organization
    Challenges in Enriching Animal Environments in a Contract Research...
    Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
    Speaker: Michelle Weideman, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    4
    FEB 05, 2014 | 9:00 AM
    C.E. CREDITS
    Certifying competence
    Certifying competence
    Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
    Speaker: Bryan R Howard, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    42
     
     
  • FEB 05, 2014 | 8:00 AM
    The 8th Edition of the Guide: An Environmental Impact
    The 8th Edition of the Guide: An Environmental Impact
    The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
    Speaker: John Bradfield, PhD, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 05, 2014 | 7:00 AM
    C.E. CREDITS
    Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs
    Simplifying Rodent Surgery... Tips for improving technique without...
    Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    47
    FEB 05, 2014 | 6:00 AM
    C.E. CREDITS
    Bedding vs. Thermoregulation
    Bedding vs. Thermoregulation
    This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
    Speaker: Andrea Gay
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    28 1
    NOV 20, 2013 | 11:00 AM
    Tools to accelerate biomarker screening for CDx
    Tools to accelerate biomarker screening for CDx
    ...
    Speaker: Dan Rhodes, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    199
    NOV 08, 2013 | 12:00 PM
    Childhood cancer with various genomic assay including whole genome sequencing
    Childhood cancer with various genomic assay including whole genome...
    The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
    Speaker: Jaime Guidry Auvil, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    4
     
     
  • OCT 17, 2013 | 9:00 AM
    Using DNASTAR Software to Identify Cancer Variations in Targeted Resequencing Data
    Using DNASTAR Software to Identify Cancer Variations in Targeted...
    DNASTAR offers an integrated suite of software for assembling and analyzing data from all major next-generation sequencing platforms. The software supports a variety of reference guided and d...
    Speaker: Matthew Keyser, MS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    48
    OCT 17, 2013 | 6:00 AM
    A Bioinformatics Approach to Clinical Sequencing
    A Bioinformatics Approach to Clinical Sequencing
    The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
    Speaker: Dan Rhodes, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
    Resistance to AR Signaling Inhibitors in Castration Resistant...
    While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
    Speaker: Elahe A Mostaghel, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    68
    OCT 16, 2013 | 9:00 AM
    C.E. CREDITS
    Keynote: Breast Cancer Genomics and Genetics
    Keynote: Breast Cancer Genomics and Genetics
    It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
    Speaker: Charles M. Perou, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    132
     
     
  • OCT 16, 2013 | 6:00 AM
    Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium development of a tool for clinical research applications
    Building an Ion AmpliSeq Colon and Lung Cancer Panel - Consortium...
    The knowledge of molecular alterations involved in colon carcinoma (CRC) and non-small-cell lung carcinoma (NSCLC) has significantly increased in the past few years. Molecular subgroups of t...
    Speaker: Nicola Normanno, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    102
    AUG 22, 2013 | 4:00 PM
    C.E. CREDITS
    Complexity of Mammalian Transcription
    Complexity of Mammalian Transcription
    The next generation sequencing technologies are profoundly influencing our way to study biology. We have previously developed cap-analysis gene expression (CAGE) to simultaneously mRNA/noncod...
    Speaker: Piero Carninci, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    50
    AUG 22, 2013 | 3:00 PM
    C.E. CREDITS
    Evaluation challenges and regulatory considerations for next-generation sequencing and other high throughput genomic technology based clinical applications
    Evaluation challenges and regulatory considerations for next-generation...
    The use of ultrahigh throughput diagnostic tests that determine genetic sequence variation to guide patient care is rapidly expanding, fueled by the enormous growth in sequencing platform dev...
    Speaker: Živana Težak, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    282
    AUG 22, 2013 | 2:00 PM
    The Road to Genomic Medicine is Paved with Data and Information
    The Road to Genomic Medicine is Paved with Data and Information
    Since the introduction of second-generation DNS sequencing technologies in 2007, the cost of genome sequencing has been consistently by 33% per quarter, with the $1000 genome arriving in 2012...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    110
    AUG 22, 2013 | 1:00 PM
    Dominant regulation of gene expression by microRNAs
    Dominant regulation of gene expression by microRNAs
    MicroRNAs are short non-coding cellular regulators of gene expression. Each microRNA controls the expression of a large set of genes, and microRNAs collectively, may regulate more than half o...
    Speaker: Noam Shomron, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    121
     
     
  • AUG 22, 2013 | 12:00 PM
    C.E. CREDITS
    Exome Sequencing as a Diagnostic Tool
    Exome Sequencing as a Diagnostic Tool
    It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
    Speaker: Pinar Bayrak-Toydemir, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    66
    AUG 22, 2013 | 10:00 AM
    C.E. CREDITS
    Using Prostate Cancer Exome Data to Identify Candidate Genes
    Using Prostate Cancer Exome Data to Identify Candidate Genes
    In this presentation, exome data from individuals with prostate cancer will be aligned against an annotated reference human genome and SNPs will be identified using DNASTARs SeqMan NGen softw...
    Speaker: Matthew Keyser, MS
    Presented at: Genetics and Genomics Virtual Event Series 2013
    60
    AUG 22, 2013 | 10:00 AM
    C.E. CREDITS
    Clinical Interpretation of Sequence Variants
    Clinical Interpretation of Sequence Variants
    The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
    Speaker: Elaine Lyon, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    72
    AUG 22, 2013 | 9:00 AM
    Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
    Next-Gen Sequencing: Driving the Transition from Genetics to Genomics
    The rapid advancements in next generation sequencing have served the research market very well, delivering more and more sequence for less and less money. While these advancements are still b...
    Speaker: Shawn Baker, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    222
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