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    Methodology

    Methodology: is a system of methods used in an area of study. The methodology used in an experiment is crucial to its success. When a piece of research is published in a scientific journal, the researchers always carefully describe their methodology.

    Webinars

    • DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      NOV 16, 2020 | 5:00 AM
      Diabetes and the Clinical Laboratory
      Diabetes and the Clinical Laboratory
      DATE: November 16, 2020 TIME: 05:00am PST, 2:00pm CET It may be impossible to stop the inexorable move towards pandemic levels of diabetes, but we can improve the glycaemic control in our pa...
      Speaker: Professor Garry John, PhD, FRCPath
      Sponsored By: Abbott Diagnostics
      11 1
      November 13, 2020 5:00 PM PST | November 14, 2020 9:00 AM SGT
      Representative sampling to address tumor heterogeneity
      Representative sampling to address tumor heterogeneity
      Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
      Speaker: Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      2
      November 12, 2020 10:00 AM PST | 5:00 PM GMT
      Representative sampling to address tumor heterogeneity
      Representative sampling to address tumor heterogeneity
      Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
      Speaker: Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 09, 2020 | 10:00 AM
      TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM TRANSCRIPTOME TO PROTEOME
      TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM...
      Date: November 9th, 2020 Time: 10:00am PDT SARS-CoV-2 continues to spread rapidly with critically ill patients admitted to the intensive care unit (ICU), where the mortality rate is reported...
      Speaker: Douglas Fraser
      Sponsored By: Thermo Fisher Scientific
      16 2
      NOV 05, 2020 | 12:00 AM
      Stigma and Substance Use: Evidence and Myths
      Stigma and Substance Use: Evidence and Myths
      Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
      Speaker: Thomas S. Franko, PharmD, BCACP
      Presented at: Opioid Crisis Virtual Event Series 2020
      2
      NOV 05, 2020 | 12:00 AM
      MAT's Not For Me: Addressing Stigma Toward MAT within the Recovery Community
      MAT's Not For Me: Addressing Stigma Toward MAT within the Recovery...
      Substance use disorder (SUD) remains a highly stigmatized medical condition in the US. One of the most effective methods of treatment for SUD, specifically for opioid use disorder and alcoho...
      Speaker: Glenn E. Sterner III, PhD
      Presented at: Opioid Crisis Virtual Event Series 2020
      2
      OCT 28, 2020 | 7:00 AM
      Guiding pancreatic cancer therapy by individualized epigenetics
      Guiding pancreatic cancer therapy by individualized epigenetics
      Date: October 28, 2020 Time: 7:00am (PDT), 10:00am (EDT) Although chemotherapy remains the mainstay of systemic therapy, a large number of cancer patients fail to respond to it. About half o...
      Speaker: Surajit Dhara, Ph.D. , Valentina Maran, Ph.D.
      Sponsored By: Agilent
      12
      OCT 21, 2020 | 10:30 AM
      Introduction to Supel(TM) Swift HLB: Sample Prep and Applications
      Introduction to Supel(TM) Swift HLB: Sample Prep and Applications
      Solid phase extraction has become a preferable technique for reducing matrix effects for sample preparation due to its ease of use and limited time requirements. MilliporeSigma has launched...
      Speaker: M. James Ross, PhD
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      3
      OCT 21, 2020 | 12:00 AM
      Automated consistency analysis of metabolomic and proteomic data in interlaboratory studies
      Automated consistency analysis of metabolomic and proteomic data...
      As ‘omics research advances, separations data such as chromatograms and nuclear magnetic resonance (NMR) spectra are being used as direct inputs to machine-learning algorithms ranging...
      Speaker: Dr. David A. Sheen
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 01, 2020 | 10:00 AM
      Improvements to Bile Collection Studies in Rats
      Improvements to Bile Collection Studies in Rats
      Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
      Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
      Sponsored By: SAI Infusion Technologies
      5 3
      SEP 30, 2020 | 12:00 PM
      Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
      Efficient Generation of Gene-edited Mouse Models and Cell Lines...
      The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
      Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      4
      SEP 29, 2020 | 7:00 AM
      Considerations in the Use of Analytical Ultracentrifugation for Characterization of AAV Gene Delivery Vectors
      Considerations in the Use of Analytical Ultracentrifugation for...
      Date: September 29, 2020 Time: 10:00am PTD, 1:00pm EDT alytical Ultracentrifugation (AUC) in the biopharmaceutical industry has traditionally been employed in the analysis of aggregation and...
      Speaker: Christopher Sucato
      Sponsored By: Beckman Coulter Life Sciences
      6 1
      SEP 23, 2020 | 11:30 AM
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
      Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 10:30 AM
      Practical Mass Cytometry
      Practical Mass Cytometry
      On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
      Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 10, 2020 | 12:00 AM
      Long read sequencing of the 16S-23S rRNA operon to characterize gut microbial changes associated with multiple sclerosis
      Long read sequencing of the 16S-23S rRNA operon to characterize...
      The microbiome has emerged as a major contributor to human health and disease. Numerous sources implicate shifts in the gut microbiome as potentially pathologic for a variety of autoimmune d...
      Speaker: Erin Longbrake, MD, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Identifying and linking antimicrobial resistance genes in metagenomes with new DNA sequencing technologies
      Identifying and linking antimicrobial resistance genes in metagenomes...
      The transfer of antimicrobial resistance genes (ARG) to pathogenic microbes is a major concern in modern medicine. Antibiotic therapies are often rendered ineffective by horizontal acquisiti...
      Speaker: Derek Bickhart, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 01, 2020 | 8:00 AM
      Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
      Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
      DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
      Speaker: Justin Balko
      Sponsored By: Thermo Fisher Scientific
      20 1
      AUG 27, 2020 | 7:00 AM
      SARS-CoV-2 Quality Control for Molecular and Serology assays
      SARS-CoV-2 Quality Control for Molecular and Serology assays
      SARS-CoV-2 has created significant challenges for laboratories, requiring the development, validation, and scale up of testing in a very short time period--often this was done for multiple m...
      Speaker: Duane Newton, PhD, D(ABMM), FIDSA , Elitza S. Theel, PhD, D(ABMM)
      Presented at: A Bio-Rad Quality Control Virtual Conference
      Sponsored By: Bio-Rad Laboratories
      20 2
      AUG 11, 2020 | 9:00 AM
      The Role of Interferon Gamma Release Assay (IGRA) Testing in the TB Testing Program
      The Role of Interferon Gamma Release Assay (IGRA) Testing in the...
      DATE: August 11, 2020 TIME: 8:00am PDT The goal of TB elimination, less than 1 case per million people per year, can only be achieved through a concerted effort to detect and treat persons i...
      Speaker: Marie-Claire Rowlinson
      Sponsored By: Diasorin
      22 4
      JUL 08, 2020 | 11:00 PM
      Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
      Mass Spectrometry Past and Present - Emerging Technologies and...
      DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
      Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
      Sponsored By: Waters Corporation
      17
      JUL 07, 2020 | 6:30 AM
      Deep immunophenotyping of cancer microenvironments by Imaging Mass Cytometryâ„¢
      Deep immunophenotyping of cancer microenvironments by Imaging...
      Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
      Speaker: Noel de Miranda, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 02, 2020 | 12:45 PM
      Strategies to normalize miRNA expression in serum and plasma
      Strategies to normalize miRNA expression in serum and plasma
      MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      2
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
    NOV 16, 2020 | 5:00 AM
    Diabetes and the Clinical Laboratory
    Diabetes and the Clinical Laboratory
    DATE: November 16, 2020 TIME: 05:00am PST, 2:00pm CET It may be impossible to stop the inexorable move towards pandemic levels of diabetes, but we can improve the glycaemic control in our pa...
    Speaker: Professor Garry John, PhD, FRCPath
    Sponsored By: Abbott Diagnostics
    11 1
    November 13, 2020 5:00 PM PST | November 14, 2020 9:00 AM SGT
    Representative sampling to address tumor heterogeneity
    Representative sampling to address tumor heterogeneity
    Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
    Speaker: Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    2
    November 12, 2020 10:00 AM PST | 5:00 PM GMT
    Representative sampling to address tumor heterogeneity
    Representative sampling to address tumor heterogeneity
    Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
    Speaker: Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 09, 2020 | 10:00 AM
    TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM TRANSCRIPTOME TO PROTEOME
    TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM...
    Date: November 9th, 2020 Time: 10:00am PDT SARS-CoV-2 continues to spread rapidly with critically ill patients admitted to the intensive care unit (ICU), where the mortality rate is reported...
    Speaker: Douglas Fraser
    Sponsored By: Thermo Fisher Scientific
    16 2
     
     
  • NOV 05, 2020 | 12:00 AM
    Stigma and Substance Use: Evidence and Myths
    Stigma and Substance Use: Evidence and Myths
    Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
    Speaker: Thomas S. Franko, PharmD, BCACP
    Presented at: Opioid Crisis Virtual Event Series 2020
    2
    NOV 05, 2020 | 12:00 AM
    MAT's Not For Me: Addressing Stigma Toward MAT within the Recovery Community
    MAT's Not For Me: Addressing Stigma Toward MAT within the Recovery...
    Substance use disorder (SUD) remains a highly stigmatized medical condition in the US. One of the most effective methods of treatment for SUD, specifically for opioid use disorder and alcoho...
    Speaker: Glenn E. Sterner III, PhD
    Presented at: Opioid Crisis Virtual Event Series 2020
    2
    OCT 28, 2020 | 7:00 AM
    Guiding pancreatic cancer therapy by individualized epigenetics
    Guiding pancreatic cancer therapy by individualized epigenetics
    Date: October 28, 2020 Time: 7:00am (PDT), 10:00am (EDT) Although chemotherapy remains the mainstay of systemic therapy, a large number of cancer patients fail to respond to it. About half o...
    Speaker: Surajit Dhara, Ph.D. , Valentina Maran, Ph.D.
    Sponsored By: Agilent
    12
    OCT 21, 2020 | 10:30 AM
    Introduction to Supel(TM) Swift HLB: Sample Prep and Applications
    Introduction to Supel(TM) Swift HLB: Sample Prep and Applications
    Solid phase extraction has become a preferable technique for reducing matrix effects for sample preparation due to its ease of use and limited time requirements. MilliporeSigma has launched...
    Speaker: M. James Ross, PhD
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    3
    OCT 21, 2020 | 12:00 AM
    Automated consistency analysis of metabolomic and proteomic data in interlaboratory studies
    Automated consistency analysis of metabolomic and proteomic data...
    As ‘omics research advances, separations data such as chromatograms and nuclear magnetic resonance (NMR) spectra are being used as direct inputs to machine-learning algorithms ranging...
    Speaker: Dr. David A. Sheen
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
     
     
  • OCT 01, 2020 | 10:00 AM
    Improvements to Bile Collection Studies in Rats
    Improvements to Bile Collection Studies in Rats
    Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
    Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
    Sponsored By: SAI Infusion Technologies
    5 3
    SEP 30, 2020 | 12:00 PM
    Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
    Efficient Generation of Gene-edited Mouse Models and Cell Lines...
    The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
    Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    4
    SEP 29, 2020 | 7:00 AM
    Considerations in the Use of Analytical Ultracentrifugation for Characterization of AAV Gene Delivery Vectors
    Considerations in the Use of Analytical Ultracentrifugation for...
    Date: September 29, 2020 Time: 10:00am PTD, 1:00pm EDT alytical Ultracentrifugation (AUC) in the biopharmaceutical industry has traditionally been employed in the analysis of aggregation and...
    Speaker: Christopher Sucato
    Sponsored By: Beckman Coulter Life Sciences
    6 1
    SEP 23, 2020 | 11:30 AM
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
    Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 10:30 AM
    Practical Mass Cytometry
    Practical Mass Cytometry
    On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
    Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
     
     
  • SEP 10, 2020 | 12:00 AM
    Long read sequencing of the 16S-23S rRNA operon to characterize gut microbial changes associated with multiple sclerosis
    Long read sequencing of the 16S-23S rRNA operon to characterize...
    The microbiome has emerged as a major contributor to human health and disease. Numerous sources implicate shifts in the gut microbiome as potentially pathologic for a variety of autoimmune d...
    Speaker: Erin Longbrake, MD, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    Identifying and linking antimicrobial resistance genes in metagenomes with new DNA sequencing technologies
    Identifying and linking antimicrobial resistance genes in metagenomes...
    The transfer of antimicrobial resistance genes (ARG) to pathogenic microbes is a major concern in modern medicine. Antibiotic therapies are often rendered ineffective by horizontal acquisiti...
    Speaker: Derek Bickhart, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 01, 2020 | 8:00 AM
    Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
    Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
    DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
    Speaker: Justin Balko
    Sponsored By: Thermo Fisher Scientific
    20 1
    AUG 27, 2020 | 7:00 AM
    SARS-CoV-2 Quality Control for Molecular and Serology assays
    SARS-CoV-2 Quality Control for Molecular and Serology assays
    SARS-CoV-2 has created significant challenges for laboratories, requiring the development, validation, and scale up of testing in a very short time period--often this was done for multiple m...
    Speaker: Duane Newton, PhD, D(ABMM), FIDSA , Elitza S. Theel, PhD, D(ABMM)
    Presented at: A Bio-Rad Quality Control Virtual Conference
    Sponsored By: Bio-Rad Laboratories
    20 2
    AUG 11, 2020 | 9:00 AM
    The Role of Interferon Gamma Release Assay (IGRA) Testing in the TB Testing Program
    The Role of Interferon Gamma Release Assay (IGRA) Testing in the...
    DATE: August 11, 2020 TIME: 8:00am PDT The goal of TB elimination, less than 1 case per million people per year, can only be achieved through a concerted effort to detect and treat persons i...
    Speaker: Marie-Claire Rowlinson
    Sponsored By: Diasorin
    22 4
     
     
  • JUL 08, 2020 | 11:00 PM
    Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
    Mass Spectrometry Past and Present - Emerging Technologies and...
    DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
    Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
    Sponsored By: Waters Corporation
    17
    JUL 07, 2020 | 6:30 AM
    Deep immunophenotyping of cancer microenvironments by Imaging Mass Cytometryâ„¢
    Deep immunophenotyping of cancer microenvironments by Imaging...
    Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
    Speaker: Noel de Miranda, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
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    JUL 02, 2020 | 12:45 PM
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    Strategies to normalize miRNA expression in serum and plasma
    MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
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    JUN 30, 2020 | 9:00 AM
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    Sponsored By: Sartorius
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