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    Monoclonal proteins

    Monoclonal proteins, also called M proteins, are elevated in the blood and urine of patients with multiple myeloma or monoclonal gammopathy of undetermined significance (MGUS), a condition which is highly correlated to bone marrow and blood cancers. Monoclonal proteins are antibodies produced in the bone marrow by the cancerous cells.

    Webinars

    • JUL 01, 2017 | 8:00 AM
      New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells
      New Monoclonal Antibodies to Defined Cell Surface Proteins on...
      The availability of well-characterised monoclonal antibodies (mAbs) detecting cell-surface epitopes on human pluripotent stem cells (hPSCs) provides useful research tools to investigate the c...
      Speaker: Andrew Laslett
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      MAY 10, 2017 | 9:00 AM
      A Semi-Automated High-Throughput Transient Expression and Purification Platform using the Expi293 Expression System
      A Semi-Automated High-Throughput Transient Expression and Purification...
      We have developed a semi-automated, high-throughput transient expression and purification system that yields milligram quantities of hundreds of proteins weekly. Starting from a glycerol stoc...
      Speaker: Matthew McKenna
      Presented at: 2017 Gibco ExpressionWorld
      4
      MAY 02, 2017 | 8:00 AM
      Counteracting tumor evasion of antibody immunity, free webinar and Q&A session
      Counteracting tumor evasion of antibody immunity, free webinar...
      DATE: May 2, 2017TIME: 8:00am PT, 11:00am ET, 4:00pm GMT, 5:00pm CETThe natural immune responses that patients develop to their own tumors, as well as therapeutic regimens employin...
      Speaker: Zhiqiang An, Ph.D.
      Presented at: Abcam virtual exhibition: support and products to advance your research
      Sponsored By: Abcam
      8 1
      FEB 20, 2017 | 8:00 AM
      Tips, hints and trouble shooting: optimization of your recombinant protein preparation workflow
      Tips, hints and trouble shooting: optimization of your recombinant...
      First established in the 1880’s, cell culture is the process by which cells are grown in a laboratory under controlled environment. The culturing of different kinds of cells supports sc...
      Speaker: Quangvu Nguyen
      Presented at: Protein Research Live
      5
      NOV 03, 2016 | 1:30 PM
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
      We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
      Speaker: Fabrizio Bonelli, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      OCT 11, 2016 | 7:00 AM
      Two Dimensional Liquid Chromatography Applied to the Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates
      Two Dimensional Liquid Chromatography Applied to the Characterization...
      DATE:  October 11, 2016 TIME:  7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
      Speaker: Koen Sandra, PhD
      Sponsored By: Agilent Genomics, Agilent Genomics
      5
      JUN 15, 2016 | 7:30 AM
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
      Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
      Speaker: Guinevere Kammeijer, MSc
      Sponsored By: Sciex, Sciex
      11 2
      MAY 04, 2016 | 12:00 PM
      Development of a Mammalian Recombinant Protein Production Suite
      Development of a Mammalian Recombinant Protein Production Suite
      Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
      Speaker: Catherine Owczarek, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAY 04, 2016 | 10:00 AM
      The ExpiCHO transient expression system: Optimization of monoclonal antibody protein A purification
      The ExpiCHO transient expression system: Optimization of monoclonal...
      The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
      Speaker: Lina Mpanda, MSc.
      Presented at: 2016 Gibco ExpressionWorld
      2
      JAN 15, 2016 | 4:00 AM
      Multiplex IHC and novel monoclonal antibodies as enabling tools for the study of tumor immunology
      Multiplex IHC and novel monoclonal antibodies as enabling tools...
      DATE: January 15, 2016 TIME: 7am EST, 12pm UK, 1pm CET With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
      Speaker: Matthew Silver, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      10 1
      OCT 15, 2015 | 7:30 AM
      WEBINAR: Graduate from Shaker to Fermentor
      WEBINAR: Graduate from Shaker to Fermentor
      DATE: October 15, 2015 TIME: 7:30AM PDT, 10:30AM EDT Most cell biologists culture cells in dishes and shake flasks to produce proteins and biological molecules; however the production of ...
      Speaker: Michelet Dorceus
      Sponsored By: Eppendorf, Eppendorf
      8 1
      OCT 07, 2014 | 8:00 AM
      Comprehensive characterization of mAbs in a single analysis
      Comprehensive characterization of mAbs in a single analysis
       In this Webinar, we will present a comprehensive characterization of a representative monoclonal antibody trypsin-digest in a single analysis. Both small and large peptides (3-65 amino acids...
      Speaker: Bryan Fonslow, PhD
      Sponsored By: Sciex, Sciex
      28
      MAY 28, 2014 | 10:30 AM
      Heavy/Light Chain Combination Assays: What Laboratories should know about M-Protein detection
      Heavy/Light Chain Combination Assays: What Laboratories should...
      Traditional testing methods for monoclonal protein in Plasma Cell Dyscrasias correctly identify a majority of patients. However, limitations in these methods can cause patients to be missed...
      Speaker: Richard O'Hara, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      87
      MAY 28, 2014 | 7:30 AM
      Technical Challenges and Standardization of Vitamin D
      Technical Challenges and Standardization of Vitamin D
      Variability of vitamin D results remains a hot topic today as more options are available to laboratories. This webinar examines how clinical and analytical factors such as vitamin D binding...
      Speaker: James Freeman, BS
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      14
      AUG 21, 2013 | 6:00 AM
      C.E. CREDITS
      M-protein Evaluation in an Age of Automation: Capillary Electrophoresis, Free Light Chains & Heavy-Light Measurements
      M-protein Evaluation in an Age of Automation: Capillary Electrophoresis,...
      This presentation focuses on contemporary methods for detection of monoclonal proteins (M-protiens) that are associated with multiple myeloma and other plasma cell dyscrasias. The basic princ...
      Speaker: David F Keren, MD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      46
    JUL 01, 2017 | 8:00 AM
    New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells
    New Monoclonal Antibodies to Defined Cell Surface Proteins on...
    The availability of well-characterised monoclonal antibodies (mAbs) detecting cell-surface epitopes on human pluripotent stem cells (hPSCs) provides useful research tools to investigate the c...
    Speaker: Andrew Laslett
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
    MAY 10, 2017 | 9:00 AM
    A Semi-Automated High-Throughput Transient Expression and Purification Platform using the Expi293 Expression System
    A Semi-Automated High-Throughput Transient Expression and Purification...
    We have developed a semi-automated, high-throughput transient expression and purification system that yields milligram quantities of hundreds of proteins weekly. Starting from a glycerol stoc...
    Speaker: Matthew McKenna
    Presented at: 2017 Gibco ExpressionWorld
    4
    MAY 02, 2017 | 8:00 AM
    Counteracting tumor evasion of antibody immunity, free webinar and Q&A session
    Counteracting tumor evasion of antibody immunity, free webinar...
    DATE: May 2, 2017TIME: 8:00am PT, 11:00am ET, 4:00pm GMT, 5:00pm CETThe natural immune responses that patients develop to their own tumors, as well as therapeutic regimens employin...
    Speaker: Zhiqiang An, Ph.D.
    Presented at: Abcam virtual exhibition: support and products to advance your research
    Sponsored By: Abcam
    8 1
    FEB 20, 2017 | 8:00 AM
    Tips, hints and trouble shooting: optimization of your recombinant protein preparation workflow
    Tips, hints and trouble shooting: optimization of your recombinant...
    First established in the 1880’s, cell culture is the process by which cells are grown in a laboratory under controlled environment. The culturing of different kinds of cells supports sc...
    Speaker: Quangvu Nguyen
    Presented at: Protein Research Live
    5
    NOV 03, 2016 | 1:30 PM
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
    We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
    Speaker: Fabrizio Bonelli, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
     
     
  • OCT 11, 2016 | 7:00 AM
    Two Dimensional Liquid Chromatography Applied to the Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates
    Two Dimensional Liquid Chromatography Applied to the Characterization...
    DATE:  October 11, 2016 TIME:  7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
    Speaker: Koen Sandra, PhD
    Sponsored By: Agilent Genomics, Agilent Genomics
    5
    JUN 15, 2016 | 7:30 AM
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
    Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
    Speaker: Guinevere Kammeijer, MSc
    Sponsored By: Sciex, Sciex
    11 2
    MAY 04, 2016 | 12:00 PM
    Development of a Mammalian Recombinant Protein Production Suite
    Development of a Mammalian Recombinant Protein Production Suite
    Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
    Speaker: Catherine Owczarek, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    MAY 04, 2016 | 10:00 AM
    The ExpiCHO transient expression system: Optimization of monoclonal antibody protein A purification
    The ExpiCHO transient expression system: Optimization of monoclonal...
    The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
    Speaker: Lina Mpanda, MSc.
    Presented at: 2016 Gibco ExpressionWorld
    2
    JAN 15, 2016 | 4:00 AM
    Multiplex IHC and novel monoclonal antibodies as enabling tools for the study of tumor immunology
    Multiplex IHC and novel monoclonal antibodies as enabling tools...
    DATE: January 15, 2016 TIME: 7am EST, 12pm UK, 1pm CET With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
    Speaker: Matthew Silver, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    10 1
     
     
  • OCT 15, 2015 | 7:30 AM
    WEBINAR: Graduate from Shaker to Fermentor
    WEBINAR: Graduate from Shaker to Fermentor
    DATE: October 15, 2015 TIME: 7:30AM PDT, 10:30AM EDT Most cell biologists culture cells in dishes and shake flasks to produce proteins and biological molecules; however the production of ...
    Speaker: Michelet Dorceus
    Sponsored By: Eppendorf, Eppendorf
    8 1
    OCT 07, 2014 | 8:00 AM
    Comprehensive characterization of mAbs in a single analysis
    Comprehensive characterization of mAbs in a single analysis
     In this Webinar, we will present a comprehensive characterization of a representative monoclonal antibody trypsin-digest in a single analysis. Both small and large peptides (3-65 amino acids...
    Speaker: Bryan Fonslow, PhD
    Sponsored By: Sciex, Sciex
    28
    MAY 28, 2014 | 10:30 AM
    Heavy/Light Chain Combination Assays: What Laboratories should know about M-Protein detection
    Heavy/Light Chain Combination Assays: What Laboratories should...
    Traditional testing methods for monoclonal protein in Plasma Cell Dyscrasias correctly identify a majority of patients. However, limitations in these methods can cause patients to be missed...
    Speaker: Richard O'Hara, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    87
    MAY 28, 2014 | 7:30 AM
    Technical Challenges and Standardization of Vitamin D
    Technical Challenges and Standardization of Vitamin D
    Variability of vitamin D results remains a hot topic today as more options are available to laboratories. This webinar examines how clinical and analytical factors such as vitamin D binding...
    Speaker: James Freeman, BS
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    14
    AUG 21, 2013 | 6:00 AM
    C.E. CREDITS
    M-protein Evaluation in an Age of Automation: Capillary Electrophoresis, Free Light Chains & Heavy-Light Measurements
    M-protein Evaluation in an Age of Automation: Capillary Electrophoresis,...
    This presentation focuses on contemporary methods for detection of monoclonal proteins (M-protiens) that are associated with multiple myeloma and other plasma cell dyscrasias. The basic princ...
    Speaker: David F Keren, MD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    46
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