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        25th NIMH Conference on Mental Health Services Research (MHSR)
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        Malnutrition in Clinical Settings: Research Gaps and Opportunities
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      • Solutions for dendritic cell research
        JUL 12, 2022
        Solutions for dendritic cell research
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        JUL 14, 2022
        Imaging long-range neuronal connections in the mouse brain by light sheet fluorescence expansion microscopy
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        FASTQ to final report: An ultra-fast workflow for comprehensive genomic profiling
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        Detection of SARS-CoV-2 antibodies using an innovative approach: dried blood spots offer the possibility of home-based self-collection
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        JUL 20, 2022
        Lessons From The Laboratory: Optimizing Your Tissue Processing
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        JUL 21, 2022
        T cell analysis - Fine-tuning your T cell research workflow step by step
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      • The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf® Gene Expression Test for Kidney Rejection
        JUN 30, 2022
        The PCR Advantage: How the Biomark™ HD System Enhances the TruGraf® Gene Expression Test for Kidney Rejection
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        JUN 30, 2022
        How and Why to Enter the Digital Laboratory
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        MultiFLEX applications in Flow Cytometry
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        JUN 29, 2022
        Live Webinar - Leading the Industry in Direct Trace Elemental Analysis of Seawater with NexION ICPMS
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        JUN 29, 2022
        Two years into the COVID-19 pandemic... What can serology testing tell us about immune status?
      • Insights into Structure, Dynamics, and Function of Endocytic Vesicles on the STELLARIS Confocal Platform
        JUN 29, 2022
        Insights into Structure, Dynamics, and Function of Endocytic Vesicles on the STELLARIS Confocal Platform
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    Nuclear Receptor

    Nuclear Receptor: Is a protein found within cells that is responsible for observing steroid and thyroid hormones. These receptors work with other proteins to monitor the expression of specific genes. They are able to control the development, homeostasis, and metabolism of the organism.

    Webinars

    • FEB 24, 2021 3:00 PM PST
      C.E. CREDITS
      PROTACs: A Chemistry Journey of Protein Degraders
      FEB 24, 2021 3:00 PM PST
      PROTACs: A Chemistry Journey of Protein Degraders
      This talk reviews the advances in the field of Proteolysis Targeting Chimeras (PROTACs). It is divided to five topics: (1) Ligand-induced Target Protein Destabilization; (2) Small-Molecule L...
      Speaker: Jie Jack Li, PhD
      Presented at: Drug Discovery & Development 2021Sponsored By: ChemPartner
      JUL 08, 2020 8:00 AM PDT
      C.E. CREDITS
      Advancing Targeted Protein Degradation Research with Automated Western Blotting
      JUL 08, 2020 8:00 AM PDT
      Advancing Targeted Protein Degradation Research with Automated...
      DATE: July 8, 2020 TIME: 8:00am PDT In this webinar, discover how targeted protein degradation is being used to drive drug discovery. Hosted by Gary Allenby, Chief Executive Officer of Aurel...
      Speaker: Dr. Gary Allenby
      Sponsored By: Bio-Techne
      JAN 31, 2019 7:30 AM PST
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      JAN 31, 2019 7:30 AM PST
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing 2019
      OCT 10, 2018 12:00 PM PDT
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      OCT 10, 2018 12:00 PM PDT
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology 2018Sponsored By: QIAGEN
      OCT 10, 2018 7:30 AM PDT
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      OCT 10, 2018 7:30 AM PDT
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology 2018
      OCT 10, 2018 6:00 AM PDT
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      OCT 10, 2018 6:00 AM PDT
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology 2018Sponsored By: QIAGEN
      MAY 22, 2018 8:00 AM PDT
      Drug development with nuclear receptor knockout and humanized rat models
      MAY 22, 2018 8:00 AM PDT
      Drug development with nuclear receptor knockout and humanized...
      DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
      Speaker: Kevin Forbes, PhD , Andrew Brown, MS
      Sponsored By: Horizon Discovery
      FEB 21, 2018 1:30 PM PST
      Can CADD Drive GPCR Drug Design? Rapid Estimation of Relative Binding Affinities Based on Pre-computed Ensembles
      FEB 21, 2018 1:30 PM PST
      Can CADD Drive GPCR Drug Design? Rapid Estimation of Relative...
      Rapid, accurate estimation of relative ligand affinities offers the potential to allow computational methods to direct drug design and development.  Towards this goal we have developed t...
      Speaker: Alexander MacKerell, PhD
      Presented at: Drug Discovery 2018
      FEB 21, 2018 9:00 AM PST
      New Tools for Understanding Allosteric Signaling in G Protein Coupled Receptors
      FEB 21, 2018 9:00 AM PST
      New Tools for Understanding Allosteric Signaling in G Protein...
      One-third of FDA-approved drugs target G protein-coupled receptors (GPCRs), transmembrane cell surface proteins that recognize small molecules and polypeptides with diverse chemical scaffolds...
      Speaker: Matthew Eddy, PhD
      Presented at: Drug Discovery 2018
      JUL 25, 2017 9:00 AM PDT
      WEBINAR: Functional Genomics and Drug Metabolism
      JUL 25, 2017 9:00 AM PDT
      WEBINAR: Functional Genomics and Drug Metabolism
      EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
      Speaker: David Piper, PhD
      Sponsored By: Thermo Fisher Scientific
      MAY 16, 2017 9:00 AM PDT
      WEBINAR: Disease Models
      MAY 16, 2017 9:00 AM PDT
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      MAY 01, 2017 8:00 AM PDT
      Using iPSCs and Genome Engineering to Build Disease Models
      MAY 01, 2017 8:00 AM PDT
      Using iPSCs and Genome Engineering to Build Disease Models
      Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
      Speaker: David Piper, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      NOV 03, 2016 1:30 PM PDT
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
      NOV 03, 2016 1:30 PM PDT
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
      We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
      Speaker: Fabrizio Bonelli, PhD
      Presented at: Clinical Diagnostics & Research
      SEP 20, 2016 7:00 AM PDT
      Advanced Analysis of Complex Cell Models with the New Operetta CLS HCA System
      SEP 20, 2016 7:00 AM PDT
      Advanced Analysis of Complex Cell Models with the New Operetta...
      DATE: September 20th, 2016 TIME:  7:00AM PST, 10:00AM ET There is a growing trend towards developing in vitro cell models that recapitulate the in vivo environment in basic research,...
      Speaker: Jacob Tesdorpf, PhD , Joe Trask
      Sponsored By: PerkinElmer, Inc., PerkinElmer, Inc., PerkinElmer, Inc.
      MAR 19, 2015 10:30 AM PDT
      Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor Systems: 3 Decades of Progress
      MAR 19, 2015 10:30 AM PDT
      Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor...
      Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
      Speaker: Dean Wong, MD, PhD
      Presented at: Neuroscience
      OCT 29, 2014 6:00 AM PDT
      Expanding the scope of RNA-Seq to archival FFPE samples
      OCT 29, 2014 6:00 AM PDT
      Expanding the scope of RNA-Seq to archival FFPE samples
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett, M.S.
      Presented at: Cancer: Research, Discovery and Therapeutics
      MAY 30, 2014 7:30 AM PDT
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      MAY 30, 2014 7:30 AM PDT
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett and Jeoffrey Schageman
      Presented at: Clinical Diagnostics and Research
      MAR 19, 2014 1:00 PM PDT
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      MAR 19, 2014 1:00 PM PDT
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
      Speaker: Radosveta Koldamova, MD, PhD
      Presented at: Neuroscience
    FEB 24, 2021 3:00 PM PST
    C.E. CREDITS
    PROTACs: A Chemistry Journey of Protein Degraders
    FEB 24, 2021 3:00 PM PST
    PROTACs: A Chemistry Journey of Protein Degraders
    This talk reviews the advances in the field of Proteolysis Targeting Chimeras (PROTACs). It is divided to five topics: (1) Ligand-induced Target Protein Destabilization; (2) Small-Molecule L...
    Speaker: Jie Jack Li, PhD
    Presented at: Drug Discovery & Development 2021Sponsored By: ChemPartner
    JUL 08, 2020 8:00 AM PDT
    C.E. CREDITS
    Advancing Targeted Protein Degradation Research with Automated Western Blotting
    JUL 08, 2020 8:00 AM PDT
    Advancing Targeted Protein Degradation Research with Automated...
    DATE: July 8, 2020 TIME: 8:00am PDT In this webinar, discover how targeted protein degradation is being used to drive drug discovery. Hosted by Gary Allenby, Chief Executive Officer of Aurel...
    Speaker: Dr. Gary Allenby
    Sponsored By: Bio-Techne
    JAN 31, 2019 7:30 AM PST
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    JAN 31, 2019 7:30 AM PST
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing 2019
    OCT 10, 2018 12:00 PM PDT
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    OCT 10, 2018 12:00 PM PDT
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology 2018Sponsored By: QIAGEN
    OCT 10, 2018 7:30 AM PDT
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    OCT 10, 2018 7:30 AM PDT
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology 2018
     
     
  • OCT 10, 2018 6:00 AM PDT
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    OCT 10, 2018 6:00 AM PDT
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology 2018Sponsored By: QIAGEN
    MAY 22, 2018 8:00 AM PDT
    Drug development with nuclear receptor knockout and humanized rat models
    MAY 22, 2018 8:00 AM PDT
    Drug development with nuclear receptor knockout and humanized...
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    Speaker: Kevin Forbes, PhD , Andrew Brown, MS
    Sponsored By: Horizon Discovery
    FEB 21, 2018 1:30 PM PST
    Can CADD Drive GPCR Drug Design? Rapid Estimation of Relative Binding Affinities Based on Pre-computed Ensembles
    FEB 21, 2018 1:30 PM PST
    Can CADD Drive GPCR Drug Design? Rapid Estimation of Relative...
    Rapid, accurate estimation of relative ligand affinities offers the potential to allow computational methods to direct drug design and development.  Towards this goal we have developed t...
    Speaker: Alexander MacKerell, PhD
    Presented at: Drug Discovery 2018
    FEB 21, 2018 9:00 AM PST
    New Tools for Understanding Allosteric Signaling in G Protein Coupled Receptors
    FEB 21, 2018 9:00 AM PST
    New Tools for Understanding Allosteric Signaling in G Protein...
    One-third of FDA-approved drugs target G protein-coupled receptors (GPCRs), transmembrane cell surface proteins that recognize small molecules and polypeptides with diverse chemical scaffolds...
    Speaker: Matthew Eddy, PhD
    Presented at: Drug Discovery 2018
    JUL 25, 2017 9:00 AM PDT
    WEBINAR: Functional Genomics and Drug Metabolism
    JUL 25, 2017 9:00 AM PDT
    WEBINAR: Functional Genomics and Drug Metabolism
    EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science...
    Speaker: David Piper, PhD
    Sponsored By: Thermo Fisher Scientific
     
     
  • MAY 16, 2017 9:00 AM PDT
    WEBINAR: Disease Models
    MAY 16, 2017 9:00 AM PDT
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    MAY 01, 2017 8:00 AM PDT
    Using iPSCs and Genome Engineering to Build Disease Models
    MAY 01, 2017 8:00 AM PDT
    Using iPSCs and Genome Engineering to Build Disease Models
    Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
    Speaker: David Piper, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    NOV 03, 2016 1:30 PM PDT
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
    NOV 03, 2016 1:30 PM PDT
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
    We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
    Speaker: Fabrizio Bonelli, PhD
    Presented at: Clinical Diagnostics & Research
    SEP 20, 2016 7:00 AM PDT
    Advanced Analysis of Complex Cell Models with the New Operetta CLS HCA System
    SEP 20, 2016 7:00 AM PDT
    Advanced Analysis of Complex Cell Models with the New Operetta...
    DATE: September 20th, 2016 TIME:  7:00AM PST, 10:00AM ET There is a growing trend towards developing in vitro cell models that recapitulate the in vivo environment in basic research,...
    Speaker: Jacob Tesdorpf, PhD , Joe Trask
    Sponsored By: PerkinElmer, Inc., PerkinElmer, Inc., PerkinElmer, Inc.
    MAR 19, 2015 10:30 AM PDT
    Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor Systems: 3 Decades of Progress
    MAR 19, 2015 10:30 AM PDT
    Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor...
    Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autor...
    Speaker: Dean Wong, MD, PhD
    Presented at: Neuroscience
     
     
  • OCT 29, 2014 6:00 AM PDT
    Expanding the scope of RNA-Seq to archival FFPE samples
    OCT 29, 2014 6:00 AM PDT
    Expanding the scope of RNA-Seq to archival FFPE samples
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett, M.S.
    Presented at: Cancer: Research, Discovery and Therapeutics
    MAY 30, 2014 7:30 AM PDT
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    MAY 30, 2014 7:30 AM PDT
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett and Jeoffrey Schageman
    Presented at: Clinical Diagnostics and Research
    MAR 19, 2014 1:00 PM PDT
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
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    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
    Speaker: Radosveta Koldamova, MD, PhD
    Presented at: Neuroscience
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