Skin: is the thin layer of tissue forming the natural outer covering of the body of a person or animal. The skin is the largest organ of the body, with a total area of about 20 square feet. The skin protects us from microbes and the elements, helps regulate body temperature, and permits the sensations of touch, heat, and cold.
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Effective functioning of the immune system relies upon systems of checks and balances; too little activity results in overwhelming infection, too much activity results in excessive damage to...
Psoriatic arthritis (PsA) is a chronic inflammatory disease affecting the joints, entheses, and skin, while also increasing the risk of cardiovascular disease (CVD) and metabolic dysfunction...
The oral cavity acts as the gateway to the respiratory and digestive tract, and is in continuity with the skin, sharing several of its features and structure. The oral cavity consists of var...
Inflammatory skin disorders comprise a diverse set of conditions exhibiting unique characteristics. Our objective was to systematically compare the affected and unaffected skin of individual...
The skin epidermis is the body's main defense against dehydration and harmful substances. We used germ-free mice to show that the microbiota is essential for proper differentiation and r...
Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, is characterized by malignant T-cell skin infiltration leading to inflammation and skin barrier defects. To effecti...
Long COVID, now recognized as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), represents a significant and growing concern in public health and medical communities. As the COVID-19 pande...
Understanding the spatial organization of the immune response within tumors is crucial for developing effective cancer immunotherapies. In this seminar, we delve into the interactions betwee...
Human skin is characterized by a limited number of phyla including, Actinomycetota, Bacillota and Pseudomonadota. In particular, Staphylococcus (Bacillota) and Corynebacterium (Actinomycetot...
Our understanding of cancer mechanisms, genetics and complexities continues to expand rapidly. Without a streamlined, standardized and easy to understand organizational system to keep track...
Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
Date: June 30, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Subclinical acute rejection (SubAR) is a significant risk for kidney transplant recipients, affecting 1 in 4 patients. Ea...
Date: November 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) Analysis of SARS-CoV-2–specific T cells is important to understand their role during acute disease and in long-term protection...
Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
The Human Microbiome Project was conceived almost 15 years ago, as an extension of the Human Genome Project, to explore the diversity of human-associated microorganisms at multiple body site...