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Tau Protein
Tau Protein: microtubule-associated protein that accumulates in neurons in neurofibrillary degeneration in a wide variety of disorders including Alzheimer’s disease; gene for tau protein situated on chromosome 17; normal role for tau protein is to stabilize microtubules; abnormal phosphorylation of tau protein destabilizes microtubules, which causes degenerative change.
SEP 27, 2022 | 10:00 AM
Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
APR 27, 2022 | 9:00 AM
Date: April 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Abnormal accumulation of misfolded tau protein in filaments characterizes more than 20 neurodegenerative diseases—c...
MAR 10, 2022 | 11:55 PM
Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
AUG 25, 2021 | 1:30 PM
In this preliminary experiment, we used spatial transcriptomics to assess the gene expression profiles of microglia or astrocytes in relation to their distance from plaques. We compared 18-m...
AUG 25, 2021 | 7:30 AM
The misfolding of intrinsically disordered proteins (IDPs) such as tau and α-synuclein (αSyn) has been associated with the on-set and progression of Alzheimer’s (AD) and Pa...
JUN 09, 2021 | 7:00 AM
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
DEC 09, 2020 | 8:00 AM
Date: December 89 2020 Time: 8:00am (PST), 11:00am (EST) This talk introduces the Leica STELLARIS 8 τ-STED system where STED Nanoscopy meets Leica’s Fast Lifetime Contrast (FALCON)...
OCT 08, 2020 | 7:00 AM
DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
MAR 11, 2020 | 1:30 PM
Neurodegenerative disease research can be considerably accelerated by using fibrillar or oligomeric constructs of prion-like proteins in in vitro or in vivo studies. These exist in a variety...
JAN 01, 2020 | 6:00 AM
Misfolded and accumulated neurodegenerative disease associated proteins (NDAPs, such as tau and alpha-synuclein) represent the major pathological hallmark in Alzheimer’s and Parkinson&...
DEC 04, 2019 | 7:00 AM
DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
NOV 19, 2019 | 10:00 AM
DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
NOV 18, 2019 | 7:00 AM
DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
JUN 05, 2019 | 5:00 PM
DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
MAY 16, 2019 | 4:00 PM
DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
FEB 27, 2019 | 8:00 AM
DATE: February 27, 2019TIME: 8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
DEC 06, 2018 | 9:00 AM
DATE: December 6, 2018TIME: 9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
JUN 08, 2017 | 10:00 AM
DATE: June 8, 2017TIME: 10:00AM PDT, 1:00PM EDT, 7:00PM CESTAlzheimer’s Disease (AD) is the result of complex interactions between risk factors that cause pleiotropic changes in m...