Transcription factors are cellular proteins that modulate gene expression by binding to DNA. These proteins work by decoding genomic information to express a specific and unique set of genes within each cell in the body. They bind to short, conserved DNA sequences located within the promoter region.
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FEB 21, 2024 | 12:00 PM
C.E. CREDITS
mRNA‑based products are rapidly growing in the biotherapeutics space. Important considerations need to be made to develop a process for mRNA synthesis that consistently generates high‑yield...
Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
MAR 22, 2023 | 9:00 AM
C.E. CREDITS
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
Date: September 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Development and evolution are controlled, to a large degree, by regions of genomic DNA called enhancers that encode...
Date: September 20, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Variation in gene expression among cell types, tissues, and organisms is commonly examined by reverse transcription...
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
APR 20, 2021 | 12:00 AM
C.E. CREDITS
The recent explosion in the sample sizes and diversity of omics assays has created exciting new opportunities for biomedical scientists. However, connecting these omics data types in an inte...
Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
Date: October 28, 2020 Time: 7:00am (PDT), 10:00am (EDT) Although chemotherapy remains the mainstay of systemic therapy, a large number of cancer patients fail to respond to it. About half o...
DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...