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    Animal Models

    Animal Models a living organisms in which normative biology or behavior can be studied, or in which a spontaneous or induced pathological process can be investigated, and in which the phenomenon in one or more respects resembles the same phenomenon in humans or other species of animal.

    Webinars

    • FEB 24, 2022 | 9:00 AM
      Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate Detection and Interpretation of Cytokine Expression
      Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate...
      Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
      Speaker: Laura Hocum Stone , Scott Hunter Oppler
      Sponsored By: ACD - A Bio-Techne Brand
      7
      FEB 23, 2022 | 11:55 PM
      Development and Characterization of an In Vitro Integrated Organ Platform for the Evaluation of Pharmacokinetic and Toxicologic Effects of Drugs and Chemicals
      Development and Characterization of an In Vitro Integrated Organ...
      The quest for alternatives to animal safety testing has fueled the development, characterization, and validation of many new technologies. There have been advances in cell and tissue models...
      Speaker: James McKim, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      3
      DEC 07, 2021 | 10:00 AM
      An overview of a novel RNAscopeâ„¢ in situ hybridization technology, and applications in pathology of animal models
      An overview of a novel RNAscopeâ„¢ in situ hybridization technology,...
      Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
      Speaker: Anushka Dikshit, PhD , Sebastien Monette
      Sponsored By: ACD, a Bio-Techne brand
      1
      DEC 07, 2021 | 9:00 AM
      Enhanced ACE2 humanized rodent models to make COVID-19 research more translatable
      Enhanced ACE2 humanized rodent models to make COVID-19 research...
      Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
      Speaker: Justin Zhao, PhD
      Sponsored By: Envigo
      4 1
      NOV 04, 2021 | 8:00 AM
      Label 3Differently - how 3D-IF-validated antibodies provide clear signals from cleared tissues in large-scale 3D imaging
      Label 3Differently - how 3D-IF-validated antibodies provide clear...
      Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
      Speaker: Dr. Markus Habich
      Sponsored By: Miltenyi Biotec
      2
      NOV 03, 2021 | 7:00 AM
      Fully humanized mouse models for Immuno-Oncology preclinical drug candidate selection
      Fully humanized mouse models for Immuno-Oncology preclinical drug...
      Date: November 3, 2021 Time: 7:00am (PDT), 10:00am (EDT) The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provid...
      Speaker: Sébastien Tabruyn
      Sponsored By: Miltenyi Biotec
      5
      OCT 26, 2021 | 8:00 AM
      Maximizing tumor microenvironment analysis for TILs from limited patient samples
      Maximizing tumor microenvironment analysis for TILs from limited...
      Date: October 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) A complex interaction among heterogenous immune and tumor cells within the tumorous tissue not only influences tumor progression, but...
      Speaker: Dr. César Evaristo
      Sponsored By: Miltenyi Biotec
      5
      OCT 14, 2021 | 8:00 AM
      Ensure reproducibility in your B cell analysis
      Ensure reproducibility in your B cell analysis
      Date: October 14, 2021 Time: 8:00am (PDT), 11:00am (EDT) The primary role of B cells is to secrete antibodies, boosting our adaptive immune responses, making them an essential part of our im...
      Speaker: Urmi Roy, PhD , Dr. Susanne Bethke
      Sponsored By: Miltenyi Biotec
      15
      OCT 07, 2021 | 10:00 AM
      Optimizing tumor study performance:  Evaluating the B-NDG & NSGâ„¢ models in PDX and CDX tumor studies.
      Optimizing tumor study performance: Evaluating the B-NDG & NSGâ„¢...
      Date: October 07, 2021 Time: 10:00am (PDT), 1:00pm (EDT) It's estimated than less than 10% of investigational anti-cancer drugs successfully achieve FDA approval for clinical use. This i...
      Speaker: Viktoria Hyddmark
      Sponsored By: Envigo
      3 1
      SEP 08, 2021 | 12:00 AM
      SeXX Matters for Respiratory Viral Pathogenesis and Responses to Vaccines
      SeXX Matters for Respiratory Viral Pathogenesis and Responses...
      The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in COVID-...
      Speaker: Sabra L. Klein, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      AUG 25, 2021 | 10:30 AM
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
      Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
      Speaker: Jason D. Hinman, PhD, MD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: Luminex
      2
      AUG 25, 2021 | 12:00 AM
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
      Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
      Speaker: Andrii Domanskyi, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      5
      AUG 25, 2021 | 12:00 AM
      Learning Electrical Connectomes of Neuropsychiatric Disorders and Behaviors
      Learning Electrical Connectomes of Neuropsychiatric Disorders...
      Targeted stimulation of the brain has the potential to treat mental illnesses but designing an appropriate protocol requires a multitude of choices. I will describe an approach to help desig...
      Speaker: David Carlson, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
      AUG 25, 2021 | 12:00 AM
      Alpha-Synuclein Strains in Synucleinopathies
      Alpha-Synuclein Strains in Synucleinopathies
      Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of É‘-...
      Speaker: Wouter Peelaerts, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      2
      AUG 25, 2021 | 12:00 AM
      A Novel Mouse Model of Ataxia Telangiectasia for Testing Small Molecule Readthrough (SMRT) Compounds
      A Novel Mouse Model of Ataxia Telangiectasia for Testing Small...
      Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      APR 20, 2021 | 12:00 AM
      C.E. CREDITS
      Low error rate long-reads enable the identification of long variant haplotypes in metagenome assemblies
      Low error rate long-reads enable the identification of long variant...
      Microbial communities include distinct lineages of closely related organisms which have proved challenging to separate in metagenomic assembly. Challenges include the existence of highly rel...
      Speaker: Derek Bickhart, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      2
      APR 20, 2021 | 12:00 AM
      X Chromosome Factors that Contribute to Sex Differences in Disease
      X Chromosome Factors that Contribute to Sex Differences in Disease
      Many diseases show sex differences in incidence or progression, suggesting that one sex has inherent biological factors that protect from or exacerbate disease. Historically the root causes...
      Speaker: Arthur P. Arnold, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      3
      APR 20, 2021 | 12:00 AM
      Epigenetic Aging Studies in Mammals
      Epigenetic Aging Studies in Mammals
      In mammals, DNA methylation is an epigenetic mark that regulates gene expression by serving as a maintainable mark whose absence marks promoters and enhancers. Recent epidemiological studies...
      Speaker: Steve Horvath
      Presented at: Genetics Week Virtual Event Series 2021
      6
      APR 07, 2021 | 12:00 AM
      Anti-fibrotic materials for immunoprotected cell-based therapies
      Anti-fibrotic materials for immunoprotected cell-based therapies
      Cell encapsulation within semi-permeable devices represents a local immunoisolation strategy for cell-based therapies without the need for systemic immunosuppression. The encapsulation syste...
      Speaker: Dr. Matthew Bochenek, PhD
      Presented at: Bioprocessing Virtual Event Series 2021
      1
      MAR 11, 2021 | 8:00 AM
      A highly quantitative in vitro method for mechanistic genotoxicity screening
      A highly quantitative in vitro method for mechanistic genotoxicity...
      Date: March 11, 2021 Time: 8:00am (PST), 11:00am (EST) g the toxicity profile of a compound is a necessity across industries and the various stages of drug development. Early stage mechanism...
      Speaker: Urmi Roy, PhD , Dr. Giel Hendriks
      Sponsored By: Miltenyi Biotec
      14
      FEB 10, 2021 | 12:00 AM
      Refining Pain Management for Laboratory Mice
      Refining Pain Management for Laboratory Mice
      Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
      Speaker: Paulin Jirkof, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      4
      FEB 10, 2021 | 12:00 AM
      The Experimental Design Assistant: an interactive web-based tool to provide bespoke feedback on experimental plans for in vivo studies
      The Experimental Design Assistant: an interactive web-based tool...
      There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
      Speaker: Dr. Esther Pearl
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      2
      FEB 10, 2021 | 12:00 AM
      How to improve rodent aseptic surgery at your facility using household products: Press N' Seal and Reynolds Wrap Foil
      How to improve rodent aseptic surgery at your facility using household...
      Learning Objectives: 1. Methods on how to aseptically use foil (Reynolds Wrap) in rodent surgery 2. Methods on how aseptically use cling film (Press N' Seal) in rodent surgery 3. Long-te...
      Speaker: Raphael A. Malbrue, DVM, MS, CertAqV
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      5
    FEB 24, 2022 | 9:00 AM
    Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate Detection and Interpretation of Cytokine Expression
    Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate...
    Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
    Speaker: Laura Hocum Stone , Scott Hunter Oppler
    Sponsored By: ACD - A Bio-Techne Brand
    7
    FEB 23, 2022 | 11:55 PM
    Development and Characterization of an In Vitro Integrated Organ Platform for the Evaluation of Pharmacokinetic and Toxicologic Effects of Drugs and Chemicals
    Development and Characterization of an In Vitro Integrated Organ...
    The quest for alternatives to animal safety testing has fueled the development, characterization, and validation of many new technologies. There have been advances in cell and tissue models...
    Speaker: James McKim, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    3
    DEC 07, 2021 | 10:00 AM
    An overview of a novel RNAscopeâ„¢ in situ hybridization technology, and applications in pathology of animal models
    An overview of a novel RNAscopeâ„¢ in situ hybridization technology,...
    Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
    Speaker: Anushka Dikshit, PhD , Sebastien Monette
    Sponsored By: ACD, a Bio-Techne brand
    1
    DEC 07, 2021 | 9:00 AM
    Enhanced ACE2 humanized rodent models to make COVID-19 research more translatable
    Enhanced ACE2 humanized rodent models to make COVID-19 research...
    Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
    Speaker: Justin Zhao, PhD
    Sponsored By: Envigo
    4 1
    NOV 04, 2021 | 8:00 AM
    Label 3Differently - how 3D-IF-validated antibodies provide clear signals from cleared tissues in large-scale 3D imaging
    Label 3Differently - how 3D-IF-validated antibodies provide clear...
    Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
    Speaker: Dr. Markus Habich
    Sponsored By: Miltenyi Biotec
    2
     
     
  • NOV 03, 2021 | 7:00 AM
    Fully humanized mouse models for Immuno-Oncology preclinical drug candidate selection
    Fully humanized mouse models for Immuno-Oncology preclinical drug...
    Date: November 3, 2021 Time: 7:00am (PDT), 10:00am (EDT) The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provid...
    Speaker: Sébastien Tabruyn
    Sponsored By: Miltenyi Biotec
    5
    OCT 26, 2021 | 8:00 AM
    Maximizing tumor microenvironment analysis for TILs from limited patient samples
    Maximizing tumor microenvironment analysis for TILs from limited...
    Date: October 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) A complex interaction among heterogenous immune and tumor cells within the tumorous tissue not only influences tumor progression, but...
    Speaker: Dr. César Evaristo
    Sponsored By: Miltenyi Biotec
    5
    OCT 14, 2021 | 8:00 AM
    Ensure reproducibility in your B cell analysis
    Ensure reproducibility in your B cell analysis
    Date: October 14, 2021 Time: 8:00am (PDT), 11:00am (EDT) The primary role of B cells is to secrete antibodies, boosting our adaptive immune responses, making them an essential part of our im...
    Speaker: Urmi Roy, PhD , Dr. Susanne Bethke
    Sponsored By: Miltenyi Biotec
    15
    OCT 07, 2021 | 10:00 AM
    Optimizing tumor study performance:  Evaluating the B-NDG & NSGâ„¢ models in PDX and CDX tumor studies.
    Optimizing tumor study performance: Evaluating the B-NDG & NSGâ„¢...
    Date: October 07, 2021 Time: 10:00am (PDT), 1:00pm (EDT) It's estimated than less than 10% of investigational anti-cancer drugs successfully achieve FDA approval for clinical use. This i...
    Speaker: Viktoria Hyddmark
    Sponsored By: Envigo
    3 1
    SEP 08, 2021 | 12:00 AM
    SeXX Matters for Respiratory Viral Pathogenesis and Responses to Vaccines
    SeXX Matters for Respiratory Viral Pathogenesis and Responses...
    The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in COVID-...
    Speaker: Sabra L. Klein, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
     
     
  • AUG 25, 2021 | 10:30 AM
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
    Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
    Speaker: Jason D. Hinman, PhD, MD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: Luminex
    2
    AUG 25, 2021 | 12:00 AM
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
    Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
    Speaker: Andrii Domanskyi, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    5
    AUG 25, 2021 | 12:00 AM
    Learning Electrical Connectomes of Neuropsychiatric Disorders and Behaviors
    Learning Electrical Connectomes of Neuropsychiatric Disorders...
    Targeted stimulation of the brain has the potential to treat mental illnesses but designing an appropriate protocol requires a multitude of choices. I will describe an approach to help desig...
    Speaker: David Carlson, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
    AUG 25, 2021 | 12:00 AM
    Alpha-Synuclein Strains in Synucleinopathies
    Alpha-Synuclein Strains in Synucleinopathies
    Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of É‘-...
    Speaker: Wouter Peelaerts, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    2
    AUG 25, 2021 | 12:00 AM
    A Novel Mouse Model of Ataxia Telangiectasia for Testing Small Molecule Readthrough (SMRT) Compounds
    A Novel Mouse Model of Ataxia Telangiectasia for Testing Small...
    Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
     
     
  • MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    APR 20, 2021 | 12:00 AM
    C.E. CREDITS
    Low error rate long-reads enable the identification of long variant haplotypes in metagenome assemblies
    Low error rate long-reads enable the identification of long variant...
    Microbial communities include distinct lineages of closely related organisms which have proved challenging to separate in metagenomic assembly. Challenges include the existence of highly rel...
    Speaker: Derek Bickhart, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    2
    APR 20, 2021 | 12:00 AM
    X Chromosome Factors that Contribute to Sex Differences in Disease
    X Chromosome Factors that Contribute to Sex Differences in Disease
    Many diseases show sex differences in incidence or progression, suggesting that one sex has inherent biological factors that protect from or exacerbate disease. Historically the root causes...
    Speaker: Arthur P. Arnold, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    3
    APR 20, 2021 | 12:00 AM
    Epigenetic Aging Studies in Mammals
    Epigenetic Aging Studies in Mammals
    In mammals, DNA methylation is an epigenetic mark that regulates gene expression by serving as a maintainable mark whose absence marks promoters and enhancers. Recent epidemiological studies...
    Speaker: Steve Horvath
    Presented at: Genetics Week Virtual Event Series 2021
    6
    APR 07, 2021 | 12:00 AM
    Anti-fibrotic materials for immunoprotected cell-based therapies
    Anti-fibrotic materials for immunoprotected cell-based therapies
    Cell encapsulation within semi-permeable devices represents a local immunoisolation strategy for cell-based therapies without the need for systemic immunosuppression. The encapsulation syste...
    Speaker: Dr. Matthew Bochenek, PhD
    Presented at: Bioprocessing Virtual Event Series 2021
    1
     
     
  • MAR 11, 2021 | 8:00 AM
    A highly quantitative in vitro method for mechanistic genotoxicity screening
    A highly quantitative in vitro method for mechanistic genotoxicity...
    Date: March 11, 2021 Time: 8:00am (PST), 11:00am (EST) g the toxicity profile of a compound is a necessity across industries and the various stages of drug development. Early stage mechanism...
    Speaker: Urmi Roy, PhD , Dr. Giel Hendriks
    Sponsored By: Miltenyi Biotec
    14
    FEB 10, 2021 | 12:00 AM
    Refining Pain Management for Laboratory Mice
    Refining Pain Management for Laboratory Mice
    Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
    Speaker: Paulin Jirkof, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    4
    FEB 10, 2021 | 12:00 AM
    The Experimental Design Assistant: an interactive web-based tool to provide bespoke feedback on experimental plans for in vivo studies
    The Experimental Design Assistant: an interactive web-based tool...
    There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
    Speaker: Dr. Esther Pearl
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    2
    FEB 10, 2021 | 12:00 AM
    How to improve rodent aseptic surgery at your facility using household products: Press N' Seal and Reynolds Wrap Foil
    How to improve rodent aseptic surgery at your facility using household...
    Learning Objectives: 1. Methods on how to aseptically use foil (Reynolds Wrap) in rodent surgery 2. Methods on how aseptically use cling film (Press N' Seal) in rodent surgery 3. Long-te...
    Speaker: Raphael A. Malbrue, DVM, MS, CertAqV
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    5
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