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    Animal Models

    Animal Models a living organisms in which normative biology or behavior can be studied, or in which a spontaneous or induced pathological process can be investigated, and in which the phenomenon in one or more respects resembles the same phenomenon in humans or other species of animal.

    Webinars

    • FEB 03, 2021 | 8:00 AM
      An introduction to immuno-oncology at Miltenyi Biotec
      An introduction to immuno-oncology at Miltenyi Biotec
      Date: February 3, 2021 Time: 8:00am (PST), 11:00am (EST) This introduction webinar will provide you with an overview of the general immuno-oncology (IO) research field...
      Speaker: Dr. Marcello Stein
      Sponsored By: Miltenyi Biotec
      19 2
      DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      DEC 03, 2020 | 10:00 AM
      Keynote Presentation: COVID-19 Projections for the United States
      Keynote Presentation: COVID-19 Projections for the United States
      Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
      Speaker: Ali H. Mokdad, PhD
      Presented at: Coronavirus Series
      2
      DEC 03, 2020 | 9:00 AM
      Transmission Dynamics of SARS-CoV-2: Inference and Projection
      Transmission Dynamics of SARS-CoV-2: Inference and Projection
      Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
      Speaker: Jeffrey Shaman
      Presented at: Coronavirus Series
      3
      DEC 03, 2020 | 12:00 AM
      Immunity, Aging and COVID-19 : where do we stand?
      Immunity, Aging and COVID-19 : where do we stand?
      SARS-CoV-2 had spread with speed unknown in recent history across the globe, sickening >50M people and killing over 1M. By far the most of the severe cases and deaths were registered amon...
      Speaker: Janko Nikolich-Zugich, MD, PhD
      Presented at: Coronavirus Series
      8
      DEC 03, 2020 | 12:00 AM
      Development, assessment and commercialization of serological SARS CoV-2 tests - an interdisciplinary success story
      Development, assessment and commercialization of serological SARS...
      Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
      Speaker: Mark Dürkop, PhD
      Presented at: Coronavirus Series
      3
      NOV 18, 2020 | 8:00 AM
      Whole-organ mapping using AI and light sheet microscopy
      Whole-organ mapping using AI and light sheet microscopy
      DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
      Speaker: Ali Ertürk
      Sponsored By: Miltenyi Biotec
      14
      November 13, 2020 4:00 PM PST | November 14, 2020 8:00 AM SGT
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
      Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
      Speaker: Srabani Bhaumik, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      November 12, 2020 9:00 AM PST | 4:00 PM GMT
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
      Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
      Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
      Speaker: Srabani Bhaumik, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      OCT 20, 2020 | 9:00 AM
      Understanding how in vitro macrophage assays drive IO drug development forward
      Understanding how in vitro macrophage assays drive IO drug development...
      DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
      Speaker: Thibaut Janss, PhD
      Sponsored By: Miltenyi Biotec
      6 1
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 01, 2020 | 10:00 AM
      Improvements to Bile Collection Studies in Rats
      Improvements to Bile Collection Studies in Rats
      Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
      Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
      Sponsored By: SAI Infusion Technologies
      5 3
      SEP 30, 2020 | 12:00 PM
      Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
      Efficient Generation of Gene-edited Mouse Models and Cell Lines...
      The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
      Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      4
      SEP 30, 2020 | 7:30 AM
      Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
      Keynote Presentation: Functionalizing Genome Editing Techniques...
      Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
      Speaker: Shondra Miller, PhD/Director
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Integrated DNA Technologies (IDT)
      2
      SEP 23, 2020 | 12:00 AM
      Extracellular Vesicles and Chronic Kidney Disease
      Extracellular Vesicles and Chronic Kidney Disease
      Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
      Speaker: Sargis Sedrakyan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 17, 2020 | 1:00 PM
      Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission and Reinfection in Domestic Cats
      Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission...
      Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19) and responsible for the current pandemic. Here, we present an in-depth study...
      Speaker: Jürgen A. Richt, DVM, PhD
      Presented at: Coronavirus Series
      1
      SEP 17, 2020 | 11:00 AM
      Lung-Chip - Accelerating Study of Viral Infection and Therapeutics
      Lung-Chip - Accelerating Study of Viral Infection and Therapeutics
      Infectious diseases, such as COVID-19, are challenging to study in animal models due to species differences, and conventional 2D cell-based systems lack the complexity to appropriately model...
      Speaker: Lorna Ewart, PhD
      Presented at: Coronavirus Series
      Sponsored By: Emulate
      1
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 15, 2020 | 8:00 AM
      Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
      Next generation ultra high content analysis of the tumor immune...
      DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
      Speaker: Stefan Eulitz
      Sponsored By: Miltenyi Biotec
      15 2
      SEP 10, 2020 | 12:00 AM
      Insights into Aquatic Biofilm Dynamics by High-Throughput Identification of Bacterial Isolates and Full-Length 16S rRNA Gene Surveys
      Insights into Aquatic Biofilm Dynamics by High-Throughput Identification...
      Microbial biofilms form on all aquatic surfaces and can harbor pathogenic bacteria. In the aquaculture industry, Flavobacteria species can cause serious diseases and lead to high mortality....
      Speaker: Joerg Graf, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
      A novel strategy to investigate longitudinal changes within the...
      Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
      Speaker: Candice M. Brown, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Host responses to SARS-CoV-2
      Host responses to SARS-CoV-2
      The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
      Speaker: Angela L. Rasmussen, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      2
    FEB 03, 2021 | 8:00 AM
    An introduction to immuno-oncology at Miltenyi Biotec
    An introduction to immuno-oncology at Miltenyi Biotec
    Date: February 3, 2021 Time: 8:00am (PST), 11:00am (EST) This introduction webinar will provide you with an overview of the general immuno-oncology (IO) research field...
    Speaker: Dr. Marcello Stein
    Sponsored By: Miltenyi Biotec
    19 2
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
    DEC 03, 2020 | 10:00 AM
    Keynote Presentation: COVID-19 Projections for the United States
    Keynote Presentation: COVID-19 Projections for the United States
    Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
    Speaker: Ali H. Mokdad, PhD
    Presented at: Coronavirus Series
    2
    DEC 03, 2020 | 9:00 AM
    Transmission Dynamics of SARS-CoV-2: Inference and Projection
    Transmission Dynamics of SARS-CoV-2: Inference and Projection
    Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
    Speaker: Jeffrey Shaman
    Presented at: Coronavirus Series
    3
    DEC 03, 2020 | 12:00 AM
    Immunity, Aging and COVID-19 : where do we stand?
    Immunity, Aging and COVID-19 : where do we stand?
    SARS-CoV-2 had spread with speed unknown in recent history across the globe, sickening >50M people and killing over 1M. By far the most of the severe cases and deaths were registered amon...
    Speaker: Janko Nikolich-Zugich, MD, PhD
    Presented at: Coronavirus Series
    8
     
     
  • DEC 03, 2020 | 12:00 AM
    Development, assessment and commercialization of serological SARS CoV-2 tests - an interdisciplinary success story
    Development, assessment and commercialization of serological SARS...
    Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
    Speaker: Mark Dürkop, PhD
    Presented at: Coronavirus Series
    3
    NOV 18, 2020 | 8:00 AM
    Whole-organ mapping using AI and light sheet microscopy
    Whole-organ mapping using AI and light sheet microscopy
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    Speaker: Ali Ertürk
    Sponsored By: Miltenyi Biotec
    14
    November 13, 2020 4:00 PM PST | November 14, 2020 8:00 AM SGT
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
    Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
    Speaker: Srabani Bhaumik, PhD
    Presented at: DISCOVERY Global User Symposium
    1
    November 12, 2020 9:00 AM PST | 4:00 PM GMT
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated stainer and reagents: assay optimization, imaging and future implications
    Fluorescent multiplexing of 3D spheroid FFPE with Roche automated...
    Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
    Speaker: Srabani Bhaumik, PhD
    Presented at: DISCOVERY Global User Symposium
    1
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
     
     
  • OCT 20, 2020 | 9:00 AM
    Understanding how in vitro macrophage assays drive IO drug development forward
    Understanding how in vitro macrophage assays drive IO drug development...
    DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
    Speaker: Thibaut Janss, PhD
    Sponsored By: Miltenyi Biotec
    6 1
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 01, 2020 | 10:00 AM
    Improvements to Bile Collection Studies in Rats
    Improvements to Bile Collection Studies in Rats
    Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
    Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
    Sponsored By: SAI Infusion Technologies
    5 3
    SEP 30, 2020 | 12:00 PM
    Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
    Efficient Generation of Gene-edited Mouse Models and Cell Lines...
    The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
    Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    4
    SEP 30, 2020 | 7:30 AM
    Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
    Keynote Presentation: Functionalizing Genome Editing Techniques...
    Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
    Speaker: Shondra Miller, PhD/Director
    Presented at: CRISPR Virtual Event Series 2020
    1
     
     
  • SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Integrated DNA Technologies (IDT)
    2
    SEP 23, 2020 | 12:00 AM
    Extracellular Vesicles and Chronic Kidney Disease
    Extracellular Vesicles and Chronic Kidney Disease
    Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
    Speaker: Sargis Sedrakyan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 17, 2020 | 1:00 PM
    Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission and Reinfection in Domestic Cats
    Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission...
    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19) and responsible for the current pandemic. Here, we present an in-depth study...
    Speaker: Jürgen A. Richt, DVM, PhD
    Presented at: Coronavirus Series
    1
    SEP 17, 2020 | 11:00 AM
    Lung-Chip - Accelerating Study of Viral Infection and Therapeutics
    Lung-Chip - Accelerating Study of Viral Infection and Therapeutics
    Infectious diseases, such as COVID-19, are challenging to study in animal models due to species differences, and conventional 2D cell-based systems lack the complexity to appropriately model...
    Speaker: Lorna Ewart, PhD
    Presented at: Coronavirus Series
    Sponsored By: Emulate
    1
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
     
     
  • SEP 15, 2020 | 8:00 AM
    Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
    Next generation ultra high content analysis of the tumor immune...
    DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
    Speaker: Stefan Eulitz
    Sponsored By: Miltenyi Biotec
    15 2
    SEP 10, 2020 | 12:00 AM
    Insights into Aquatic Biofilm Dynamics by High-Throughput Identification of Bacterial Isolates and Full-Length 16S rRNA Gene Surveys
    Insights into Aquatic Biofilm Dynamics by High-Throughput Identification...
    Microbial biofilms form on all aquatic surfaces and can harbor pathogenic bacteria. In the aquaculture industry, Flavobacteria species can cause serious diseases and lead to high mortality....
    Speaker: Joerg Graf, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
    A novel strategy to investigate longitudinal changes within the...
    Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
    Speaker: Candice M. Brown, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    Host responses to SARS-CoV-2
    Host responses to SARS-CoV-2
    The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
    Speaker: Angela L. Rasmussen, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    2
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