A core goal of neuroscience is to understand how the brain adaptively orchestrates movements to execute complex behaviors. Quantifying behavioral dynamics, however, has historically been pro...
The Brain Behavior Quantification and Synchronization (BBQS) program is a basic research effort in the NIH BRAIN Initiative to develop new tools and approaches in support of a more comprehen...
This talk will present the methodology of using the guided ultrasonic waves generated by the rodent to track its physiology, behavior, and psychological state. When behaving in an environmen...
We are developing the three-banded panther worm Hofstenia miamia as a new model system for neuroscience. Hofstenia is a rare, lab-tractable member of a lineage of early-branching marine inve...
The study of psychopathology is changing with the advent and pervasive use of smartphones, wearables, and connected devices together with significant advances in brain imaging. These new ave...
A central goal for neuroscience is to understand how our brains process information in real life, such as faces during natural social interactions. While we have gained important knowledge u...
The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, Alison Hanson discusses a collaborative effort aimed at coming one s...
Behaving animals continually reconcile the internal states of their neural circuits brain-wide with incoming sensory and environmental evidence to evaluate when and how to act. The brains of...
To make movement and foraging decisions in a naturalistic environment, multiple neural populations must work synergistically to produce successful actions. These decisions span multiple scal...
Virginia will discuss work on single-trial analysis of EEG signals during episodic memory tasks. They develop single-trial classifiers to predict whether people will remember pictures from E...
Individuals with substance use disorders often show impaired sensitivity to reward value. However, it is not clear whether such impairment impacts reward-related decision making and whether...
Studying motor behaviors can reveal fundamental principles of the brain and mind. This presentation focuses on our work towards developing the hardware and computational tools that will allo...
With the internet, society has been exposed to puzzling and exquisite animal behavior, while neuroscience has vastly concentrated on a few inbred animal models studied in trained unnatural s...
Diosgenin is a botanical steroidal saponin with anti-inflammatory, antioxidant, anti-thrombotic, anti- apoptotic, anti-depressant, and anti-nociceptive properties. However, it's unknown...
Spheroids and organoids, two examples of 3D cell culture models, have become invaluable tools to study the processes that dictate behavior of tissues under physiological and pathological con...
Generating Insights into tissue microenvironments is crucial to our understanding of normal and abnormal tissue development such as during cancer progression. Spatial biology methods using m...
Smartphone-based optical imaging and sensing devices are among the next-generation biosensors that have shown great potential to transform the field of point-of-care (POC) diagnostics....
The elegant and well-orchestrated molecular players responsible for normal neurodevelopment harbor the capacity for detrimental repercussions if mis-expressed at the wrong time, or in the wr...
Troubleshooting is a systematic approach designed to correct problems that may occur with patient samples, instruments, operating an analyzer, handling, reagents and quality control material...
Healthy human red blood cells (RBCs) gradually degrade over their lifespan of ~120 days. However, sickle cells - RBCs from sickle cell disease (SCD) patients - degrade much faster within the...
Clinical laboratories generate most of the objective data on which diagnostic, preventive, and therapeutic decisions are made. By considering the current availability of information analytic...
C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
3D morphological analysis of neurons often requires using different imaging modalities, capturing multiple types of neurons and inspecting neurons in a range of densities. These complexities...
We are currently facing an Opioid epidemic and a mental health crisis with increased disconnection and addiction and beginning a psychedelic renaissance. Nociplastic pain is a newer phenomen...
A core goal of neuroscience is to understand how the brain adaptively orchestrates movements to execute complex behaviors. Quantifying behavioral dynamics, however, has historically been pro...
The Brain Behavior Quantification and Synchronization (BBQS) program is a basic research effort in the NIH BRAIN Initiative to develop new tools and approaches in support of a more comprehen...
This talk will present the methodology of using the guided ultrasonic waves generated by the rodent to track its physiology, behavior, and psychological state. When behaving in an environmen...
We are developing the three-banded panther worm Hofstenia miamia as a new model system for neuroscience. Hofstenia is a rare, lab-tractable member of a lineage of early-branching marine inve...
The study of psychopathology is changing with the advent and pervasive use of smartphones, wearables, and connected devices together with significant advances in brain imaging. These new ave...
A central goal for neuroscience is to understand how our brains process information in real life, such as faces during natural social interactions. While we have gained important knowledge u...
The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, Alison Hanson discusses a collaborative effort aimed at coming one s...
Behaving animals continually reconcile the internal states of their neural circuits brain-wide with incoming sensory and environmental evidence to evaluate when and how to act. The brains of...
To make movement and foraging decisions in a naturalistic environment, multiple neural populations must work synergistically to produce successful actions. These decisions span multiple scal...
Virginia will discuss work on single-trial analysis of EEG signals during episodic memory tasks. They develop single-trial classifiers to predict whether people will remember pictures from E...
Individuals with substance use disorders often show impaired sensitivity to reward value. However, it is not clear whether such impairment impacts reward-related decision making and whether...
Studying motor behaviors can reveal fundamental principles of the brain and mind. This presentation focuses on our work towards developing the hardware and computational tools that will allo...
With the internet, society has been exposed to puzzling and exquisite animal behavior, while neuroscience has vastly concentrated on a few inbred animal models studied in trained unnatural s...
Diosgenin is a botanical steroidal saponin with anti-inflammatory, antioxidant, anti-thrombotic, anti- apoptotic, anti-depressant, and anti-nociceptive properties. However, it's unknown...
Spheroids and organoids, two examples of 3D cell culture models, have become invaluable tools to study the processes that dictate behavior of tissues under physiological and pathological con...
Generating Insights into tissue microenvironments is crucial to our understanding of normal and abnormal tissue development such as during cancer progression. Spatial biology methods using m...
Smartphone-based optical imaging and sensing devices are among the next-generation biosensors that have shown great potential to transform the field of point-of-care (POC) diagnostics....
The elegant and well-orchestrated molecular players responsible for normal neurodevelopment harbor the capacity for detrimental repercussions if mis-expressed at the wrong time, or in the wr...
Troubleshooting is a systematic approach designed to correct problems that may occur with patient samples, instruments, operating an analyzer, handling, reagents and quality control material...
Healthy human red blood cells (RBCs) gradually degrade over their lifespan of ~120 days. However, sickle cells - RBCs from sickle cell disease (SCD) patients - degrade much faster within the...
Clinical laboratories generate most of the objective data on which diagnostic, preventive, and therapeutic decisions are made. By considering the current availability of information analytic...
C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
3D morphological analysis of neurons often requires using different imaging modalities, capturing multiple types of neurons and inspecting neurons in a range of densities. These complexities...
We are currently facing an Opioid epidemic and a mental health crisis with increased disconnection and addiction and beginning a psychedelic renaissance. Nociplastic pain is a newer phenomen...