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        High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
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        A new approach of COVID-19 surveillance testing to maximize the identification of asymptomatic patients
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        Advancing Cell Biology with Cryo-Correlative Microscopy
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        Applications of Procalcitonin-aided Decision Making for Antibiotic Stewardship in Emergency Care
      • High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
        High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
      • A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
        A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
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        Uterine B cell dynamics during pregnancy - Immune regulation of the placenta
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        Endpoint assays for the characterization of rare and therapy-resistant cells in cancer
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    Chromatin Proteins

    Chromatin Proteins: The DNA double helix in the cell nucleus is packaged by special proteins termed histones. The formed protein/DNA complex is called chromatin. The basic structural unit of chromatin is the nucleosome.

    Webinars

    • FEB 21, 2018 6:00 AM PST
      Using HDAC Inhibitors to Improve Cancer Immunotherapy
      FEB 21, 2018 6:00 AM PST
      Using HDAC Inhibitors to Improve Cancer Immunotherapy
      We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
      Speaker: Alejandro Villagra, PhD
      Presented at: Drug Discovery 2018
      SEP 19, 2017 10:30 AM PDT
      WEBINAR: Structure and Function of Epigenetic Regulators in Human Disease
      SEP 19, 2017 10:30 AM PDT
      WEBINAR: Structure and Function of Epigenetic Regulators in Human...
      DATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...
      Speaker: Cigall Kadoch, PhD , Chris Fry, PhD
      Sponsored By: Cell Signaling Technology
      APR 14, 2017 10:00 AM PDT
      WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated with Age and Dietary Restriction using Targeted MS and Untargeted LC-MS Lipidomics Approaches
      APR 14, 2017 10:00 AM PDT
      WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated...
      DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
      Speaker: Kévin Contrepois , PhD
      Sponsored By: SCIEX
      FEB 23, 2017 1:30 PM PST
      Mining Dense, Dynamic Personal Data Clouds to Enhance Health
      FEB 23, 2017 1:30 PM PST
      Mining Dense, Dynamic Personal Data Clouds to Enhance Health
      Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
      Speaker: Nathan Price, PhD
      Presented at: Precision Medicine 2017
      FEB 23, 2017 12:00 PM PST
      Novel Precision medicines that exploit Proximity
      FEB 23, 2017 12:00 PM PST
      Novel Precision medicines that exploit Proximity
      Cell growth and regulation involve vast networks of interacting DNAs, RNAs, proteins, lipids and sugars. Through a fundamental strategy of life, these interactions push multiple cellular proc...
      Speaker: James Prudent, PhD
      Presented at: Precision Medicine 2017
      FEB 23, 2017 12:00 PM PST
      Rapid Learning for Precision Oncology
      FEB 23, 2017 12:00 PM PST
      Rapid Learning for Precision Oncology
      In this era of precision molecular medicine, knowledge changes rapidly and is highly dispersed.  Physicians and patients are faced with conflicting expert opinions and a shortage of acti...
      Speaker: Marty Tenenbaum, PhD
      Presented at: Precision Medicine 2017
      FEB 23, 2017 12:00 PM PST
      Recent progress in cellular medicine with an eye to precision medicine
      FEB 23, 2017 12:00 PM PST
      Recent progress in cellular medicine with an eye to precision...
      Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
      Speaker: Giacinto Scoles, PhD
      Presented at: Precision Medicine 2017
      FEB 23, 2017 10:30 AM PST
      Clinical Whole Genome Sequencing In a Healthy Population
      FEB 23, 2017 10:30 AM PST
      Clinical Whole Genome Sequencing In a Healthy Population
      Clinical whole genome sequencing (cWGS) is rapidly gaining acceptance as cost is decreasing and success rates in identifying disease-causing variants are increasing. While the application of...
      Speaker: Erica Ramos, MS, CGC
      Presented at: Precision Medicine 2017
      FEB 23, 2017 9:00 AM PST
      Metabolomics and its Role in Precision Medicine
      FEB 23, 2017 9:00 AM PST
      Metabolomics and its Role in Precision Medicine
      Although there have been enormous advances in gene sequencing, the results give massive amounts of data that only point to disease risk. Major health factors, including diet, lifestyle, envir...
      Speaker: John Ryals, PhD
      Presented at: Precision Medicine 2017
      FEB 23, 2017 7:30 AM PST
      KEYNOTE: Towards a new era of precision medicine in psychiatry: Using genetic algorithms to optimize medication outcome
      FEB 23, 2017 7:30 AM PST
      KEYNOTE: Towards a new era of precision medicine in psychiatry:...
      Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
      Speaker: Daniel Mueller, PhD
      Presented at: Precision Medicine 2017
      FEB 23, 2017 6:00 AM PST
      Validation and Commercialization of Liquid Biopsy in a CLIA Lab
      FEB 23, 2017 6:00 AM PST
      Validation and Commercialization of Liquid Biopsy in a CLIA Lab
      Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy.  A liquid biopsy provides biomarker information that...
      Speaker: Michael Nall
      Presented at: Precision Medicine 2017
      FEB 23, 2017 6:00 AM PST
      Obtaining Samples for Precision Medicine Studies: An Outsider's Perspective
      FEB 23, 2017 6:00 AM PST
      Obtaining Samples for Precision Medicine Studies: An Outsider's...
      Best practices for developing precision medicine diagnostics can include completing a retrospective analysis.  Obtaining enough samples to have a statistically significant study typicall...
      Speaker: Matt Klusas
      Presented at: Precision Medicine 2017
      FEB 22, 2017 1:30 PM PST
      Integrating genomics platforms and data in Biobanks
      FEB 22, 2017 1:30 PM PST
      Integrating genomics platforms and data in Biobanks
      Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
      Speaker: Sami Amr, PhD
      Presented at: Precision Medicine 2017
      FEB 22, 2017 12:00 PM PST
      Measurement Assurance for Tissue Engineering & Regenerative Medicine
      FEB 22, 2017 12:00 PM PST
      Measurement Assurance for Tissue Engineering & Regenerative Medicine
      Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
      Speaker: Carl Simon, PhD
      Presented at: Precision Medicine 2017
      FEB 22, 2017 12:00 PM PST
      From Bits to Bedside: Translating Big Data into Precision Medicine and Digital Health
      FEB 22, 2017 12:00 PM PST
      From Bits to Bedside: Translating Big Data into Precision Medicine...
      In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
      Speaker: Dexter Hadley, MD, PhD
      Presented at: Precision Medicine 2017
      FEB 22, 2017 10:30 AM PST
      Beyond the hype: the evidence behind the role of genetics in drug response
      FEB 22, 2017 10:30 AM PST
      Beyond the hype: the evidence behind the role of genetics in drug...
      Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
      Speaker: Matt Nelson, PhD
      Presented at: Precision Medicine 2017
      FEB 22, 2017 10:30 AM PST
      NGS live in your lab in 30 days
      FEB 22, 2017 10:30 AM PST
      NGS live in your lab in 30 days
      Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
      Speaker: Salim Essakali , Yi Kong, Ph.D.
      Presented at: Precision Medicine 2017
      FEB 22, 2017 9:00 AM PST
      The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral Processes in Autism Spectrum Disorder
      FEB 22, 2017 9:00 AM PST
      The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral...
      Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
      Speaker: Ruth Luna, PhD, MB (ASCP) CM
      Presented at: Precision Medicine 2017
      FEB 22, 2017 7:30 AM PST
      KEYNOTE: Where innovation and regulation meet
      FEB 22, 2017 7:30 AM PST
      KEYNOTE: Where innovation and regulation meet
      Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
      Speaker: Laura Koontz, PhD
      Presented at: Precision Medicine 2017
      FEB 22, 2017 6:00 AM PST
      Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
      FEB 22, 2017 6:00 AM PST
      Mate-pair next generation sequencing as a powerful clinical tool...
      Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine 2017
      FEB 22, 2017 6:00 AM PST
      GenomeFIRST ™ A new paradigm for the return of genomic results
      FEB 22, 2017 6:00 AM PST
      GenomeFIRST ™ A new paradigm for the return of genomic results
      The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
      Speaker: Marc Williams, MD
      Presented at: Precision Medicine 2017
      NOV 23, 2016 8:00 AM PST
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      NOV 23, 2016 8:00 AM PST
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      DATE: November 23rd, 2016 TIME: 8:00AM PT, 11:00AM ET The structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
      Speaker: Moritz Voelker-Albert , Andreas Schmidt
      Sponsored By: SCIEX OMICS, SCIEX OMICS
      APR 11, 2016 9:00 AM PDT
      WEBINAR: The epigenome in normal human placental development and its dysregulation in preeclampsia
      APR 11, 2016 9:00 AM PDT
      WEBINAR: The epigenome in normal human placental development and...
      9:00 AM PT, 11:00 AM CT, 12:00 PM ET Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
      Speaker: Peter Jones, Ph.D., D.Sc. , Nandor Than, MD, PhD
      Sponsored By: Zymo Research, Zymo Research
      FEB 24, 2016 3:00 PM PST
      Bringing precision medicine in oncology to South Africa
      FEB 24, 2016 3:00 PM PST
      Bringing precision medicine in oncology to South Africa
      The greatest health epidemic of our time is cancer. Deaths from cancer worldwide outnumber the combined deaths from HIV/AIDS, tuberculosis and malaria by a wide margin. There are at least 100...
      Speaker: Musa Mhlanga, PhD
      Presented at: Precision Medicine 2016
    FEB 21, 2018 6:00 AM PST
    Using HDAC Inhibitors to Improve Cancer Immunotherapy
    FEB 21, 2018 6:00 AM PST
    Using HDAC Inhibitors to Improve Cancer Immunotherapy
    We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
    Speaker: Alejandro Villagra, PhD
    Presented at: Drug Discovery 2018
    SEP 19, 2017 10:30 AM PDT
    WEBINAR: Structure and Function of Epigenetic Regulators in Human Disease
    SEP 19, 2017 10:30 AM PDT
    WEBINAR: Structure and Function of Epigenetic Regulators in Human...
    DATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...
    Speaker: Cigall Kadoch, PhD , Chris Fry, PhD
    Sponsored By: Cell Signaling Technology
    APR 14, 2017 10:00 AM PDT
    WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated with Age and Dietary Restriction using Targeted MS and Untargeted LC-MS Lipidomics Approaches
    APR 14, 2017 10:00 AM PDT
    WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated...
    DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
    Speaker: Kévin Contrepois , PhD
    Sponsored By: SCIEX
    FEB 23, 2017 1:30 PM PST
    Mining Dense, Dynamic Personal Data Clouds to Enhance Health
    FEB 23, 2017 1:30 PM PST
    Mining Dense, Dynamic Personal Data Clouds to Enhance Health
    Healthcare is becoming more proactive and data-rich than anything before possible – and will increasingly focus on maintaining and enhancing wellness more than just reacting to disease....
    Speaker: Nathan Price, PhD
    Presented at: Precision Medicine 2017
    FEB 23, 2017 12:00 PM PST
    Novel Precision medicines that exploit Proximity
    FEB 23, 2017 12:00 PM PST
    Novel Precision medicines that exploit Proximity
    Cell growth and regulation involve vast networks of interacting DNAs, RNAs, proteins, lipids and sugars. Through a fundamental strategy of life, these interactions push multiple cellular proc...
    Speaker: James Prudent, PhD
    Presented at: Precision Medicine 2017
     
     
  • FEB 23, 2017 12:00 PM PST
    Rapid Learning for Precision Oncology
    FEB 23, 2017 12:00 PM PST
    Rapid Learning for Precision Oncology
    In this era of precision molecular medicine, knowledge changes rapidly and is highly dispersed.  Physicians and patients are faced with conflicting expert opinions and a shortage of acti...
    Speaker: Marty Tenenbaum, PhD
    Presented at: Precision Medicine 2017
    FEB 23, 2017 12:00 PM PST
    Recent progress in cellular medicine with an eye to precision medicine
    FEB 23, 2017 12:00 PM PST
    Recent progress in cellular medicine with an eye to precision...
    Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
    Speaker: Giacinto Scoles, PhD
    Presented at: Precision Medicine 2017
    FEB 23, 2017 10:30 AM PST
    Clinical Whole Genome Sequencing In a Healthy Population
    FEB 23, 2017 10:30 AM PST
    Clinical Whole Genome Sequencing In a Healthy Population
    Clinical whole genome sequencing (cWGS) is rapidly gaining acceptance as cost is decreasing and success rates in identifying disease-causing variants are increasing. While the application of...
    Speaker: Erica Ramos, MS, CGC
    Presented at: Precision Medicine 2017
    FEB 23, 2017 9:00 AM PST
    Metabolomics and its Role in Precision Medicine
    FEB 23, 2017 9:00 AM PST
    Metabolomics and its Role in Precision Medicine
    Although there have been enormous advances in gene sequencing, the results give massive amounts of data that only point to disease risk. Major health factors, including diet, lifestyle, envir...
    Speaker: John Ryals, PhD
    Presented at: Precision Medicine 2017
    FEB 23, 2017 7:30 AM PST
    KEYNOTE: Towards a new era of precision medicine in psychiatry: Using genetic algorithms to optimize medication outcome
    FEB 23, 2017 7:30 AM PST
    KEYNOTE: Towards a new era of precision medicine in psychiatry:...
    Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
    Speaker: Daniel Mueller, PhD
    Presented at: Precision Medicine 2017
     
     
  • FEB 23, 2017 6:00 AM PST
    Validation and Commercialization of Liquid Biopsy in a CLIA Lab
    FEB 23, 2017 6:00 AM PST
    Validation and Commercialization of Liquid Biopsy in a CLIA Lab
    Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy.  A liquid biopsy provides biomarker information that...
    Speaker: Michael Nall
    Presented at: Precision Medicine 2017
    FEB 23, 2017 6:00 AM PST
    Obtaining Samples for Precision Medicine Studies: An Outsider's Perspective
    FEB 23, 2017 6:00 AM PST
    Obtaining Samples for Precision Medicine Studies: An Outsider's...
    Best practices for developing precision medicine diagnostics can include completing a retrospective analysis.  Obtaining enough samples to have a statistically significant study typicall...
    Speaker: Matt Klusas
    Presented at: Precision Medicine 2017
    FEB 22, 2017 1:30 PM PST
    Integrating genomics platforms and data in Biobanks
    FEB 22, 2017 1:30 PM PST
    Integrating genomics platforms and data in Biobanks
    Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
    Speaker: Sami Amr, PhD
    Presented at: Precision Medicine 2017
    FEB 22, 2017 12:00 PM PST
    Measurement Assurance for Tissue Engineering & Regenerative Medicine
    FEB 22, 2017 12:00 PM PST
    Measurement Assurance for Tissue Engineering & Regenerative Medicine
    Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
    Speaker: Carl Simon, PhD
    Presented at: Precision Medicine 2017
    FEB 22, 2017 12:00 PM PST
    From Bits to Bedside: Translating Big Data into Precision Medicine and Digital Health
    FEB 22, 2017 12:00 PM PST
    From Bits to Bedside: Translating Big Data into Precision Medicine...
    In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
    Speaker: Dexter Hadley, MD, PhD
    Presented at: Precision Medicine 2017
     
     
  • FEB 22, 2017 10:30 AM PST
    Beyond the hype: the evidence behind the role of genetics in drug response
    FEB 22, 2017 10:30 AM PST
    Beyond the hype: the evidence behind the role of genetics in drug...
    Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
    Speaker: Matt Nelson, PhD
    Presented at: Precision Medicine 2017
    FEB 22, 2017 10:30 AM PST
    NGS live in your lab in 30 days
    FEB 22, 2017 10:30 AM PST
    NGS live in your lab in 30 days
    Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
    Speaker: Salim Essakali , Yi Kong, Ph.D.
    Presented at: Precision Medicine 2017
    FEB 22, 2017 9:00 AM PST
    The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral Processes in Autism Spectrum Disorder
    FEB 22, 2017 9:00 AM PST
    The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral...
    Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
    Speaker: Ruth Luna, PhD, MB (ASCP) CM
    Presented at: Precision Medicine 2017
    FEB 22, 2017 7:30 AM PST
    KEYNOTE: Where innovation and regulation meet
    FEB 22, 2017 7:30 AM PST
    KEYNOTE: Where innovation and regulation meet
    Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
    Speaker: Laura Koontz, PhD
    Presented at: Precision Medicine 2017
    FEB 22, 2017 6:00 AM PST
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  • FEB 22, 2017 6:00 AM PST
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    Presented at: Precision Medicine 2017
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    Speaker: Moritz Voelker-Albert , Andreas Schmidt
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