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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Webinars

    • APR 19, 2022 | 1:30 PM
      C.E. CREDITS
      Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular Depletion
      Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular...
      Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
      Speaker: Dante DeAscanis
      Presented at: Genetics Week Virtual Event Series 2022
      Sponsored By: Jumpcode Genomics
      3
      APR 06, 2022 | 5:30 AM
      Leveraging Microscale Automated Bioreactors for the Design and Optimization of Microbial Cell Factories for the Production of Anticancer Drugs Taxol
      Leveraging Microscale Automated Bioreactors for the Design and...
      Currently over 95 % of pharmaceutical products and transport fuels are derived from petroleum. Sustainable alternatives are critical to achieving net-zero emissions without detriment to qual...
      Speaker: Leonardo Rios Solis, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      2
      APR 05, 2022 | 8:00 AM
      Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
      Investigating antimicrobial mechanisms-of-action using automated...
      Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
      Speaker: Ali Clark-ElSayed
      Sponsored By: Inscripta
      8
      FEB 23, 2022 | 3:00 PM
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
      Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
      Speaker: Stacey Ward, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      Sponsored By: MilliporeSigma
      1
      DEC 09, 2021 | 8:00 AM
      Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
      Reprogramming human regulatory T cell specificity with a novel...
      Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
      Speaker: Leonardo Ferreira
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      DEC 08, 2021 | 9:00 AM
      The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks with MAD TiGER
      The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks...
      Date: December 9, 2021 Time: 9:00am (PDT), 12:00am (EDT) CRISPR editing has revolutionized plant breeding, and the MAD7 CRISPR nuclease developed by InscriptaTM is democratizing access to CR...
      Speaker: Gabino Sanchez , Ben Mijts
      Sponsored By: Inscripta
      5
      NOV 30, 2021 | 8:00 AM
      ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR T Cell Manufacturing with nS/MARt Vectors
      ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR...
      Date: November 30, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA Vector Lab at the German Cancer Research Center (DKFZ) has developed Nano-S/MARt (nS/MARt), a novel DNA Vector platform that...
      Speaker: Matthias Bozza
      Sponsored By: MaxCyte®
      5
      NOV 17, 2021 | 8:00 AM
      Exosomes: From pure isolation to standardized analysis by flow cytometry
      Exosomes: From pure isolation to standardized analysis by flow...
      Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
      Speaker: Ariadna Pascual Velazquez , Laura Müller , Stefan Wild, PhD
      Sponsored By: Miltenyi Biotec
      9
      NOV 02, 2021 | 9:00 AM
      Fluorophore fundamentals for flow cytometry
      Fluorophore fundamentals for flow cytometry
      Date: November 2, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Flow cytometry is a powerful technique for the analysis of multiple parameters of individual cells within heterogeneous populations....
      Speaker: Jolene Bradford, MLS, SCYM(ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      15
      OCT 27, 2021 | 8:00 AM
      Easily upgrade your flow cytometry data with brightfield images using the Attune CytPix Flow Cytometer
      Easily upgrade your flow cytometry data with brightfield images...
      Date: October 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn about how brightfield images can take your flow cytometry data to the next level. Join Dr. Cora Chadick, Technical Director, as...
      Speaker: Cora Chadick
      Sponsored By: Thermo Fisher Scientific
      6
      OCT 14, 2021 | 7:00 AM
      Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
      Heterologous Protein Engineering and characterization of native...
      Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      22
      OCT 12, 2021 | 8:00 AM
      The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
      The growing concern of off-target effects: How to measure and...
      Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
      Speaker: Pandhita Pochanard
      Sponsored By: Thermo Fisher Scientific/Gibco
      30
      SEP 29, 2021 | 11:59 PM
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy, PhD
      Presented at: CRISPR Virtual Event Series 2021
      2 2
      SEP 29, 2021 | 12:00 PM
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
      Speaker: Domenica Martorana, PhD
      Presented at: CRISPR Virtual Event Series 2021
      Sponsored By: QIAGEN
      1
      SEP 29, 2021 | 9:00 AM
      Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome Engineering
      Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome...
      RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: CRISPR Virtual Event Series 2021
      1
      SEP 28, 2021 | 8:00 AM
      New fixable viability dyes and applications for flow cytometry
      New fixable viability dyes and applications for flow cytometry
      Date: September 28, 2021 Time: 8:00am (PDT), 11:00am (EDT) Flow cytometry provides many advantages including single-cell quantitative analysis, high sample throughput, and multiplex cell cha...
      Speaker: Chris Langsdorf
      Sponsored By: Thermo Fisher Scientific
      9 4
      SEP 23, 2021 | 10:00 AM
      From start up to scale up: Creative solutions to modernize your lab budget
      From start up to scale up: Creative solutions to modernize your...
      Date: Septembee 23, 2021 Time: 8:00am (PDT), 11:00am (EDT) Join leaders and financial experts in the biotech and clinical space to engage in discussions about overcoming financial challenges...
      Speaker: Dr. Richard Qun Shan , Jason Hansen , Travis Hardman
      Sponsored By: Thermo Fisher Scientific
      4
      SEP 17, 2021 | 12:00 PM
      Developing better techniques for 3D culture and analysis.
      Developing better techniques for 3D culture and analysis.
      Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
      Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      SEP 14, 2021 | 7:00 AM
      What prevents you from increasing your PCR productivity?
      What prevents you from increasing your PCR productivity?
      Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
      Speaker: Arora Phang, PhD
      Sponsored By: Eppendorf
      24 1
      AUG 31, 2021 | 9:00 AM
      The Regulation of ALC1 by TRIM33 during the DNA Damage Response
      The Regulation of ALC1 by TRIM33 during the DNA Damage Response
      Date: July 07, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA damage response is extremely crucial in maintaining genomic integrity. Failure to repair damaged DNA can result in the propagati...
      Speaker: Rukia Henry
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
      AUG 25, 2021 | 8:00 AM
      Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
      Improving heterologous protein production in yeast with massively...
      Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
      Speaker: Eric Abbate
      Sponsored By: Inscripta
      5 2
      AUG 25, 2021 | 12:00 AM
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
      Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
      Speaker: Andrii Domanskyi, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      5
      JUL 15, 2021 | 8:00 AM
      The Good, the Bad and the Ugly of 45 color panel design: Building to higher dimensional flow cytometry while maintaining biological resolution
      The Good, the Bad and the Ugly of 45 color panel design: Building...
      Date: July 15, 2021 Time: 8:00am (PDT), 11:00am (EDT) High dimensional full spectrum flow cytometry grants unprecedented access to previously unattainable parameters in cellular biology. Flu...
      Speaker: Seddon Thomas
      Sponsored By: Thermo Fisher Scientific
      7 2
      JUL 01, 2021 | 12:00 PM
      Mastering basic cell culture techniques
      Mastering basic cell culture techniques
      Date: July 01, 2021 Time: 09:30am IST/12:00pm SGT/01:00pm JST, KST/03:00pm AEST/ 05:00pm NZST We know that understanding cell culture is essential for life of your work. Gibco Galaxy Tour We...
      Speaker: Brittany Balhouse , Christopher Scanlon
      Sponsored By: Thermo Fisher Scientific/Gibco
      48 3
    APR 19, 2022 | 1:30 PM
    C.E. CREDITS
    Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular Depletion
    Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular...
    Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
    Speaker: Dante DeAscanis
    Presented at: Genetics Week Virtual Event Series 2022
    Sponsored By: Jumpcode Genomics
    3
    APR 06, 2022 | 5:30 AM
    Leveraging Microscale Automated Bioreactors for the Design and Optimization of Microbial Cell Factories for the Production of Anticancer Drugs Taxol
    Leveraging Microscale Automated Bioreactors for the Design and...
    Currently over 95 % of pharmaceutical products and transport fuels are derived from petroleum. Sustainable alternatives are critical to achieving net-zero emissions without detriment to qual...
    Speaker: Leonardo Rios Solis, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    2
    APR 05, 2022 | 8:00 AM
    Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
    Investigating antimicrobial mechanisms-of-action using automated...
    Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
    Speaker: Ali Clark-ElSayed
    Sponsored By: Inscripta
    8
    FEB 23, 2022 | 3:00 PM
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
    Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
    Speaker: Stacey Ward, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    Sponsored By: MilliporeSigma
    1
    DEC 09, 2021 | 8:00 AM
    Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
    Reprogramming human regulatory T cell specificity with a novel...
    Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
    Speaker: Leonardo Ferreira
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
     
     
  • DEC 08, 2021 | 9:00 AM
    The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks with MAD TiGER
    The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks...
    Date: December 9, 2021 Time: 9:00am (PDT), 12:00am (EDT) CRISPR editing has revolutionized plant breeding, and the MAD7 CRISPR nuclease developed by InscriptaTM is democratizing access to CR...
    Speaker: Gabino Sanchez , Ben Mijts
    Sponsored By: Inscripta
    5
    NOV 30, 2021 | 8:00 AM
    ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR T Cell Manufacturing with nS/MARt Vectors
    ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR...
    Date: November 30, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA Vector Lab at the German Cancer Research Center (DKFZ) has developed Nano-S/MARt (nS/MARt), a novel DNA Vector platform that...
    Speaker: Matthias Bozza
    Sponsored By: MaxCyte®
    5
    NOV 17, 2021 | 8:00 AM
    Exosomes: From pure isolation to standardized analysis by flow cytometry
    Exosomes: From pure isolation to standardized analysis by flow...
    Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
    Speaker: Ariadna Pascual Velazquez , Laura Müller , Stefan Wild, PhD
    Sponsored By: Miltenyi Biotec
    9
    NOV 02, 2021 | 9:00 AM
    Fluorophore fundamentals for flow cytometry
    Fluorophore fundamentals for flow cytometry
    Date: November 2, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Flow cytometry is a powerful technique for the analysis of multiple parameters of individual cells within heterogeneous populations....
    Speaker: Jolene Bradford, MLS, SCYM(ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    15
    OCT 27, 2021 | 8:00 AM
    Easily upgrade your flow cytometry data with brightfield images using the Attune CytPix Flow Cytometer
    Easily upgrade your flow cytometry data with brightfield images...
    Date: October 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn about how brightfield images can take your flow cytometry data to the next level. Join Dr. Cora Chadick, Technical Director, as...
    Speaker: Cora Chadick
    Sponsored By: Thermo Fisher Scientific
    6
     
     
  • OCT 14, 2021 | 7:00 AM
    Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
    Heterologous Protein Engineering and characterization of native...
    Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    22
    OCT 12, 2021 | 8:00 AM
    The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
    The growing concern of off-target effects: How to measure and...
    Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
    Speaker: Pandhita Pochanard
    Sponsored By: Thermo Fisher Scientific/Gibco
    30
    SEP 29, 2021 | 11:59 PM
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy, PhD
    Presented at: CRISPR Virtual Event Series 2021
    2 2
    SEP 29, 2021 | 12:00 PM
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
    Speaker: Domenica Martorana, PhD
    Presented at: CRISPR Virtual Event Series 2021
    Sponsored By: QIAGEN
    1
    SEP 29, 2021 | 9:00 AM
    Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome Engineering
    Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome...
    RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: CRISPR Virtual Event Series 2021
    1
     
     
  • SEP 28, 2021 | 8:00 AM
    New fixable viability dyes and applications for flow cytometry
    New fixable viability dyes and applications for flow cytometry
    Date: September 28, 2021 Time: 8:00am (PDT), 11:00am (EDT) Flow cytometry provides many advantages including single-cell quantitative analysis, high sample throughput, and multiplex cell cha...
    Speaker: Chris Langsdorf
    Sponsored By: Thermo Fisher Scientific
    9 4
    SEP 23, 2021 | 10:00 AM
    From start up to scale up: Creative solutions to modernize your lab budget
    From start up to scale up: Creative solutions to modernize your...
    Date: Septembee 23, 2021 Time: 8:00am (PDT), 11:00am (EDT) Join leaders and financial experts in the biotech and clinical space to engage in discussions about overcoming financial challenges...
    Speaker: Dr. Richard Qun Shan , Jason Hansen , Travis Hardman
    Sponsored By: Thermo Fisher Scientific
    4
    SEP 17, 2021 | 12:00 PM
    Developing better techniques for 3D culture and analysis.
    Developing better techniques for 3D culture and analysis.
    Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
    Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    SEP 14, 2021 | 7:00 AM
    What prevents you from increasing your PCR productivity?
    What prevents you from increasing your PCR productivity?
    Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
    Speaker: Arora Phang, PhD
    Sponsored By: Eppendorf
    24 1
    AUG 31, 2021 | 9:00 AM
    The Regulation of ALC1 by TRIM33 during the DNA Damage Response
    The Regulation of ALC1 by TRIM33 during the DNA Damage Response
    Date: July 07, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA damage response is extremely crucial in maintaining genomic integrity. Failure to repair damaged DNA can result in the propagati...
    Speaker: Rukia Henry
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
     
     
  • AUG 25, 2021 | 8:00 AM
    Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
    Improving heterologous protein production in yeast with massively...
    Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
    Speaker: Eric Abbate
    Sponsored By: Inscripta
    5 2
    AUG 25, 2021 | 12:00 AM
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
    Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
    Speaker: Andrii Domanskyi, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    5
    JUL 15, 2021 | 8:00 AM
    The Good, the Bad and the Ugly of 45 color panel design: Building to higher dimensional flow cytometry while maintaining biological resolution
    The Good, the Bad and the Ugly of 45 color panel design: Building...
    Date: July 15, 2021 Time: 8:00am (PDT), 11:00am (EDT) High dimensional full spectrum flow cytometry grants unprecedented access to previously unattainable parameters in cellular biology. Flu...
    Speaker: Seddon Thomas
    Sponsored By: Thermo Fisher Scientific
    7 2
    JUL 01, 2021 | 12:00 PM
    Mastering basic cell culture techniques
    Mastering basic cell culture techniques
    Date: July 01, 2021 Time: 09:30am IST/12:00pm SGT/01:00pm JST, KST/03:00pm AEST/ 05:00pm NZST We know that understanding cell culture is essential for life of your work. Gibco Galaxy Tour We...
    Speaker: Brittany Balhouse , Christopher Scanlon
    Sponsored By: Thermo Fisher Scientific/Gibco
    48 3
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