Dementia isn't a specific disease. Instead, dementia describes a group of symptoms affecting memory, thinking and social abilities severely enough to interfere with daily functioning. Though dementia generally involves memory loss, memory loss has different causes. So memory loss alone doesn't mean you have dementia. Alzheimer's disease is the most common cause of a progressive dementia in older adults, but there are a number of causes of dementia. Depending on the cause, some dementia symptoms can be reversed.
Inflammation is associated with cognitive decline and the pathogenesis of Alzheimer's disease, although exact pathways remain elusive. To further explore the role of inflammation, we uti...
C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
Date: April 25, 2023 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The presynaptic protein alpha-synuclein (α-syn) is associated with Parkinson’s disease and Lewy body dementi...
Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of É‘-...
DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
DATE: March 5, 2019TIME: 10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
The cerebellum is incorporated into the distributed neural circuits subserving motor control, cognitive processing and the modulation of emotion. This lecture provides an overview of anatomic...
DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
Review this popular and powerful method for accurate detection of low abundance proteins or changes in protein expression, presented by Dr Martin Broadstock. Review the application of fluores...
Autologous cell based interventions, which include mesenchymal stem cells, are mostly unproven therapies increasingly being applied for musculoskeletal and other medical disorders by medical ...
Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
Transforming serious brain disease through cutting edge science, generating novel medicines that enable patients to overcome everyday challenges and achieve their full potential...
Alzheimers disease (AD) is a common neurodegenerative disorder characterized clinically by progress decline in memory and thinking and pathologically by the presence of senile plaques and neu...
Alzheimers disease (AD) is a neurodegenerative disorder producing cognitive impairment and dementia in millions of elders. Currently no treatment is effective to slow the progression of AD. M...
Inflammation is associated with cognitive decline and the pathogenesis of Alzheimer's disease, although exact pathways remain elusive. To further explore the role of inflammation, we uti...
C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
Date: April 25, 2023 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The presynaptic protein alpha-synuclein (α-syn) is associated with Parkinson’s disease and Lewy body dementi...
Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of É‘-...
DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
DATE: March 5, 2019TIME: 10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
The cerebellum is incorporated into the distributed neural circuits subserving motor control, cognitive processing and the modulation of emotion. This lecture provides an overview of anatomic...
DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
Review this popular and powerful method for accurate detection of low abundance proteins or changes in protein expression, presented by Dr Martin Broadstock. Review the application of fluores...
Autologous cell based interventions, which include mesenchymal stem cells, are mostly unproven therapies increasingly being applied for musculoskeletal and other medical disorders by medical ...
Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
Transforming serious brain disease through cutting edge science, generating novel medicines that enable patients to overcome everyday challenges and achieve their full potential...
Alzheimers disease (AD) is a common neurodegenerative disorder characterized clinically by progress decline in memory and thinking and pathologically by the presence of senile plaques and neu...
Alzheimers disease (AD) is a neurodegenerative disorder producing cognitive impairment and dementia in millions of elders. Currently no treatment is effective to slow the progression of AD. M...
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