Disease: is a disorder of structure or function in a human, animal, or plant, especially one that produces specific signs or symptoms that is not simply a direct result of physical injury.
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Antibody therapeutics is a fast-growing market boosted by developments in bispecific antibodies and in newly emerging tetra-specific antibodies. With the ability to recruit a combination of...
Stem cells have the capability to develop into any specialized cell type, which makes them a valuable resource in research and regenerative medicine. Differentiated stem cell models provide...
Human cytomegalovirus (CMV) infection is common and usually results in a mild, non-specific illness in otherwise healthy individuals followed by asymptomatic latency. However, congenital CMV...
Testing for abnormal immunoglobulins was based previously on serum electrophoresis and immunofixation only. In the last years, however, free light chain (FLC) testing in serum became one imp...
Differences in how users gate populations within experiments are major sources of variability in flow cytometry data analysis. Incorporating automated image analysis can substantially reduce...
Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat...
Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
The use of adeno-associated viruses (AAV) as gene delivery vectors has vast potential for the treatment of many severe human diseases. A small group of intensively studied AAV capsids have b...
Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...