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    Host Cell Protein

    Host Cell Proteins: these are process-related impurities, expressed by the host cell used for production of biopharmaceutical proteins. Host cells express many of their own proteins that can easily contaminate the recombinant protein drug.

    Webinars

    • OCT 24, 2023 | 9:00 PM
      Protein Expression Webinar
      Protein Expression Webinar
      This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
      Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      MAR 08, 2023 | 9:00 AM
      Boost microbial detection sensitivity with unbiased human host DNA and RNA depletion
      Boost microbial detection sensitivity with unbiased human host...
      Date: March 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) An unbiased characterization of the human microbiome is crucial to a more complete understanding of microbial effect on h...
      Speaker: Zenas George, Ph.D.
      Sponsored By: Jumpcode Genomics
      8
      MAR 07, 2023 | 9:00 AM
      Enabling High-throughput Biology with New Technologies for Synthetic Construct Sequencing
      Enabling High-throughput Biology with New Technologies for Synthetic...
      Date: March 07, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) The ability to synthesize and sequence vast numbers of DNA constructs is a cornerstone of modern high-throughput biologic...
      Speaker: Joseph C. Mellor, Ph.D. , Henry Chan, Ph.D. , Bryan Jiang
      Sponsored By: seqWell
      15
      JAN 25, 2023 | 8:00 AM
      Multiplex proteomics using proximity extension assay for identification of protein biomarkers predictive of acute graft-versus-host disease in allogeneic hematopoietic cell transplantation
      Multiplex proteomics using proximity extension assay for identification...
      Date: January 25, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Allogeneic hematopoietic cell transplantation (HCT) is curative for hematological diseases; however, is also associated...
      Speaker: Ivan Pasic, Hon BSc, PhD, MD, FRCPC , Dr. Frank (Fotios) Michelis
      Sponsored By: Olink Proteomics
      15
      NOV 03, 2022 | 6:00 AM
      Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions
      Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral...
      Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
      Speaker: Mohamed Abdel-Mohsen
      Sponsored By: GenScript
      16
      OCT 19, 2022 | 6:00 AM
      Evolution of SARS-CoV-2
      Evolution of SARS-CoV-2
      At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), emerged in China. As of September 2022, SARS-CoV...
      Speaker: Kei Sato, PhD
      Presented at: Coronavirus Series
      6
      JUN 29, 2022 | 7:00 AM
      Insights into Structure, Dynamics, and Function of Endocytic Vesicles on the STELLARIS Confocal Platform
      Insights into Structure, Dynamics, and Function of Endocytic Vesicles...
      Date: June 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Imaging live cells is key to reveal their inner workings, dynamics, and function. Current technological advances in confo...
      Speaker: Julia Roberti, Ph.D.
      Sponsored By: Leica Microsystems
      5
      JUN 01, 2022 | 9:00 AM
      Analysis of process related impurities in cell & gene therapy products by SWATH LC-MS
      Analysis of process related impurities in cell & gene therapy...
      Date: June 01, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple...
      Speaker: Ejvind Mørtz
      Sponsored By: SCIEX
      3
      MAY 19, 2022 | 8:00 AM
      Automated sample preparation for reproducible clinical proteomics
      Automated sample preparation for reproducible clinical proteomics
      Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
      Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
      Sponsored By: Covaris, Inc.
      14
      APR 06, 2022 | 9:00 AM
      Keynote Presentation: Continuous Bioprocessing - New Challenges and Opportunities for Membrane Technology
      Keynote Presentation: Continuous Bioprocessing - New Challenges...
      There is growing interest in the development of integrated continuous bioprocesses for the production of important biotherapeutics due to the potential for enhanced productivity, greater fle...
      Speaker: Andrew L. Zydney, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      1
      MAR 10, 2022 | 11:55 PM
      Characterizing Pathology-Inducing Protein Aggregates as Tools for Alzheimer's and Parkinson's Disease Models and Drug Discovery
      Characterizing Pathology-Inducing Protein Aggregates as Tools...
      Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
      Speaker: Jacob McPhail, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      2 1
      DEC 08, 2021 | 7:00 AM
      Troubleshooting in bioprocessing
      Troubleshooting in bioprocessing
      Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
      Speaker: Ines Hartmann , Eric Timmermans
      Sponsored By: Eppendorf
      12
      DEC 07, 2021 | 9:00 AM
      Enhanced ACE2 humanized rodent models to make COVID-19 research more translatable
      Enhanced ACE2 humanized rodent models to make COVID-19 research...
      Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
      Speaker: Justin Zhao, PhD
      Sponsored By: Envigo
      4 1
      OCT 27, 2021 | 6:00 AM
      Comprehensive characterization of Etanercept using the ZenoTOF 7600 system
      Comprehensive characterization of Etanercept using the ZenoTOF...
      Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
      Speaker: Xuezhi Bi, PhD
      Sponsored By: SCIEX
      5
      OCT 21, 2021 | 9:00 AM
      Strategies for HCP-MS Analysis- designing the best approach for your process and product
      Strategies for HCP-MS Analysis- designing the best approach for...
      Date: October 21, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Industry guidelines for host cell protein impurity analysis emphasize the importance of process-specific and product-specific assessm...
      Speaker: Christina Morris
      Sponsored By: SCIEX
      1
      OCT 14, 2021 | 7:00 AM
      Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
      Heterologous Protein Engineering and characterization of native...
      Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      22
      SEP 08, 2021 | 12:00 AM
      Genetic Approaches and Host Targets to Inhibit Influenza Virus Pathogenesis
      Genetic Approaches and Host Targets to Inhibit Influenza Virus...
      Influenza viruses represent a significant burden to human health. In order to limit respiratory viral disease, new approaches that can prevent viral infection and spread are needed. We have...
      Speaker: Nicholas Heaton, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      SEP 08, 2021 | 12:00 AM
      Development of Self-Replicating Propagation-Defective RNAs as Next Generation Vaccine Candidates Against Human Coronaviruses
      Development of Self-Replicating Propagation-Defective RNAs as...
      Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
      Speaker: Isabel Sola, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      AUG 25, 2021 | 8:00 AM
      Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
      Improving heterologous protein production in yeast with massively...
      Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
      Speaker: Eric Abbate
      Sponsored By: Inscripta
      5 2
      AUG 25, 2021 | 12:00 AM
      Characterizing Pathogenic Protein Aggregates for Utilization as Molecular Tools to Accelerate Neurodegenerative Disease Research
      Characterizing Pathogenic Protein Aggregates for Utilization as...
      Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in society, no cur...
      Speaker: Jacob McPhail, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: StressMarq Biosciences
      1
      JUL 13, 2021 | 11:00 AM
      Monoclonality Assurance Using CloneSelect Single-Cell Printer and CloneSelect Imager in Human Stem Cell (hSC) Engineering Workflow
      Monoclonality Assurance Using CloneSelect Single-Cell Printer...
      Date: July 13, 2021 Time: 11:00am (PDT), 1:00pm (EDT) 1 R&D, Cell Culture & Fermentation Sciences, Bio Pharmaceutical Development, AstraZeneca, Gaithersburg, USA, 2 R&D, ADPE, Ce...
      Speaker: Gargi Roy
      Sponsored By: Molecular Devices
      9 10
      APR 29, 2021 | 10:00 AM
      Quantitative western blotting analysis: tips, considerations, and streamlining analysis using Invitrogen iBright Analysis Software
      Quantitative western blotting analysis: tips, considerations,...
      Date: April 29, 2021 Time: 10:00am PDT Western blotting is a fundamental application used in life science research to better understand target proteins and their function in complex systems....
      Speaker: Janaki Narahari, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5
      APR 21, 2021 | 5:00 PM
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
      Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
      Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
      Sponsored By: NanoString Technologies, Illumina
      5
      APR 21, 2021 | 12:00 AM
      Past, Present and Future of Engineered Cell Therapy
      Past, Present and Future of Engineered Cell Therapy
      Engineered cell therapy is an emerging field of science to target and treat cancer. Current strategies include utilizing immune cells such as T cells, NK cells and Macrophages or other cells...
      Speaker: Janani Krishnamurthy, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      2
    OCT 24, 2023 | 9:00 PM
    Protein Expression Webinar
    Protein Expression Webinar
    This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
    Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    MAR 08, 2023 | 9:00 AM
    Boost microbial detection sensitivity with unbiased human host DNA and RNA depletion
    Boost microbial detection sensitivity with unbiased human host...
    Date: March 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) An unbiased characterization of the human microbiome is crucial to a more complete understanding of microbial effect on h...
    Speaker: Zenas George, Ph.D.
    Sponsored By: Jumpcode Genomics
    8
    MAR 07, 2023 | 9:00 AM
    Enabling High-throughput Biology with New Technologies for Synthetic Construct Sequencing
    Enabling High-throughput Biology with New Technologies for Synthetic...
    Date: March 07, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) The ability to synthesize and sequence vast numbers of DNA constructs is a cornerstone of modern high-throughput biologic...
    Speaker: Joseph C. Mellor, Ph.D. , Henry Chan, Ph.D. , Bryan Jiang
    Sponsored By: seqWell
    15
    JAN 25, 2023 | 8:00 AM
    Multiplex proteomics using proximity extension assay for identification of protein biomarkers predictive of acute graft-versus-host disease in allogeneic hematopoietic cell transplantation
    Multiplex proteomics using proximity extension assay for identification...
    Date: January 25, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Allogeneic hematopoietic cell transplantation (HCT) is curative for hematological diseases; however, is also associated...
    Speaker: Ivan Pasic, Hon BSc, PhD, MD, FRCPC , Dr. Frank (Fotios) Michelis
    Sponsored By: Olink Proteomics
    15
    NOV 03, 2022 | 6:00 AM
    Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions
    Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral...
    Date: October 13, 2022 Time: 10:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD...
    Speaker: Mohamed Abdel-Mohsen
    Sponsored By: GenScript
    16
     
     
  • OCT 19, 2022 | 6:00 AM
    Evolution of SARS-CoV-2
    Evolution of SARS-CoV-2
    At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), emerged in China. As of September 2022, SARS-CoV...
    Speaker: Kei Sato, PhD
    Presented at: Coronavirus Series
    6
    JUN 29, 2022 | 7:00 AM
    Insights into Structure, Dynamics, and Function of Endocytic Vesicles on the STELLARIS Confocal Platform
    Insights into Structure, Dynamics, and Function of Endocytic Vesicles...
    Date: June 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Imaging live cells is key to reveal their inner workings, dynamics, and function. Current technological advances in confo...
    Speaker: Julia Roberti, Ph.D.
    Sponsored By: Leica Microsystems
    5
    JUN 01, 2022 | 9:00 AM
    Analysis of process related impurities in cell & gene therapy products by SWATH LC-MS
    Analysis of process related impurities in cell & gene therapy...
    Date: June 01, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple...
    Speaker: Ejvind Mørtz
    Sponsored By: SCIEX
    3
    MAY 19, 2022 | 8:00 AM
    Automated sample preparation for reproducible clinical proteomics
    Automated sample preparation for reproducible clinical proteomics
    Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
    Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
    Sponsored By: Covaris, Inc.
    14
    APR 06, 2022 | 9:00 AM
    Keynote Presentation: Continuous Bioprocessing - New Challenges and Opportunities for Membrane Technology
    Keynote Presentation: Continuous Bioprocessing - New Challenges...
    There is growing interest in the development of integrated continuous bioprocesses for the production of important biotherapeutics due to the potential for enhanced productivity, greater fle...
    Speaker: Andrew L. Zydney, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    1
     
     
  • MAR 10, 2022 | 11:55 PM
    Characterizing Pathology-Inducing Protein Aggregates as Tools for Alzheimer's and Parkinson's Disease Models and Drug Discovery
    Characterizing Pathology-Inducing Protein Aggregates as Tools...
    Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
    Speaker: Jacob McPhail, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    2 1
    DEC 08, 2021 | 7:00 AM
    Troubleshooting in bioprocessing
    Troubleshooting in bioprocessing
    Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
    Speaker: Ines Hartmann , Eric Timmermans
    Sponsored By: Eppendorf
    12
    DEC 07, 2021 | 9:00 AM
    Enhanced ACE2 humanized rodent models to make COVID-19 research more translatable
    Enhanced ACE2 humanized rodent models to make COVID-19 research...
    Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
    Speaker: Justin Zhao, PhD
    Sponsored By: Envigo
    4 1
    OCT 27, 2021 | 6:00 AM
    Comprehensive characterization of Etanercept using the ZenoTOF 7600 system
    Comprehensive characterization of Etanercept using the ZenoTOF...
    Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
    Speaker: Xuezhi Bi, PhD
    Sponsored By: SCIEX
    5
    OCT 21, 2021 | 9:00 AM
    Strategies for HCP-MS Analysis- designing the best approach for your process and product
    Strategies for HCP-MS Analysis- designing the best approach for...
    Date: October 21, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Industry guidelines for host cell protein impurity analysis emphasize the importance of process-specific and product-specific assessm...
    Speaker: Christina Morris
    Sponsored By: SCIEX
    1
     
     
  • OCT 14, 2021 | 7:00 AM
    Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
    Heterologous Protein Engineering and characterization of native...
    Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    22
    SEP 08, 2021 | 12:00 AM
    Genetic Approaches and Host Targets to Inhibit Influenza Virus Pathogenesis
    Genetic Approaches and Host Targets to Inhibit Influenza Virus...
    Influenza viruses represent a significant burden to human health. In order to limit respiratory viral disease, new approaches that can prevent viral infection and spread are needed. We have...
    Speaker: Nicholas Heaton, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    SEP 08, 2021 | 12:00 AM
    Development of Self-Replicating Propagation-Defective RNAs as Next Generation Vaccine Candidates Against Human Coronaviruses
    Development of Self-Replicating Propagation-Defective RNAs as...
    Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
    Speaker: Isabel Sola, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    AUG 25, 2021 | 8:00 AM
    Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
    Improving heterologous protein production in yeast with massively...
    Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
    Speaker: Eric Abbate
    Sponsored By: Inscripta
    5 2
    AUG 25, 2021 | 12:00 AM
    Characterizing Pathogenic Protein Aggregates for Utilization as Molecular Tools to Accelerate Neurodegenerative Disease Research
    Characterizing Pathogenic Protein Aggregates for Utilization as...
    Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in society, no cur...
    Speaker: Jacob McPhail, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: StressMarq Biosciences
    1
     
     
  • JUL 13, 2021 | 11:00 AM
    Monoclonality Assurance Using CloneSelect Single-Cell Printer and CloneSelect Imager in Human Stem Cell (hSC) Engineering Workflow
    Monoclonality Assurance Using CloneSelect Single-Cell Printer...
    Date: July 13, 2021 Time: 11:00am (PDT), 1:00pm (EDT) 1 R&D, Cell Culture & Fermentation Sciences, Bio Pharmaceutical Development, AstraZeneca, Gaithersburg, USA, 2 R&D, ADPE, Ce...
    Speaker: Gargi Roy
    Sponsored By: Molecular Devices
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    APR 29, 2021 | 10:00 AM
    Quantitative western blotting analysis: tips, considerations, and streamlining analysis using Invitrogen iBright Analysis Software
    Quantitative western blotting analysis: tips, considerations,...
    Date: April 29, 2021 Time: 10:00am PDT Western blotting is a fundamental application used in life science research to better understand target proteins and their function in complex systems....
    Speaker: Janaki Narahari, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5
    APR 21, 2021 | 5:00 PM
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
    Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
    Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
    Sponsored By: NanoString Technologies, Illumina
    5
    APR 21, 2021 | 12:00 AM
    Past, Present and Future of Engineered Cell Therapy
    Past, Present and Future of Engineered Cell Therapy
    Engineered cell therapy is an emerging field of science to target and treat cancer. Current strategies include utilizing immune cells such as T cells, NK cells and Macrophages or other cells...
    Speaker: Janani Krishnamurthy, PhD
    Presented at: Genetics Week Virtual Event Series 2021
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