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    Host Cell Protein

    Host Cell Proteins: these are process-related impurities, expressed by the host cell used for production of biopharmaceutical proteins. Host cells express many of their own proteins that can easily contaminate the recombinant protein drug.

    Webinars

    • MAR 17, 2021 | 8:00 AM
      Advanced enzymes to facilitate SARS-CoV-2 research
      Advanced enzymes to facilitate SARS-CoV-2 research
      Date: March 17, 2021 Time: 08:00am (PST) Research focused on SARS-CoV-2 has become a primary focus in genomic and molecular biology fields. With a constantly changing field with new methods...
      Speaker: Li Lavelle
      Sponsored By: Thermo Fisher Scientific
      24 1
      JAN 27, 2021 | 7:00 AM
      A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
      A novel automated and simultaneous protein/antibody high-throughput...
      DATE: January 27, 2020 TIME: 7:00am PST resin columns is limited by throughput and a complicated sample preparation process, which makes it challenging to extend to high...
      Speaker: Weilin Liu, PhD
      Sponsored By: GenScript
      8
      DEC 17, 2020 | 9:00 AM
      Advancing Cell Biology with Cryo-Correlative Microscopy
      Advancing Cell Biology with Cryo-Correlative Microscopy
      Date: December 17, 2020 Time: 9:00am (PST), 12:00pm (EST) Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging moda...
      Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D. , Joseph Kim
      Sponsored By: Leica Microsystems, Alveole
      13 2
      DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      OCT 15, 2020 | 8:00 AM
      Zonal Rotor Ultracentrifugation: An Effective Tool for Nanoparticle Separations at Large Scale
      Zonal Rotor Ultracentrifugation: An Effective Tool for Nanoparticle...
      DATE: October 15, 2020 TIME: 8am PDT, 11am EDT Density gradient centrifugation is an effective method for the isolation and purification of small particles. Hollow rotors capable of hosting...
      Speaker: Dr. Alexander Wittemann , Dr. Simone Plueisch
      Sponsored By: Beckman Coulter Life Sciences
      9
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: IDT
      2
      SEP 23, 2020 | 10:30 AM
      iPSC- and patient- derived intestinal organoids for gastrointestinal research
      iPSC- and patient- derived intestinal organoids for gastrointestinal...
      Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
      Speaker: Kevin Su
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      SEP 17, 2020 | 2:00 PM
      Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
      Keynote Presentation: The formation of an International Collaborative...
      Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
      Speaker: Jacqueline Fabius , Nevan Krogan, PhD
      Presented at: Coronavirus Series
      1
      SEP 17, 2020 | 9:00 AM
      Preclinical Optical Imaging of Infectious Diseases
      Preclinical Optical Imaging of Infectious Diseases
      PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
      Speaker: Kevin Francis, PhD
      Presented at: Coronavirus Series
      Sponsored By: PerkinElmer
      1
      SEP 10, 2020 | 10:00 AM
      Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
      Keynote Presentation: Squeezing out understanding from sequences:...
      Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
      Speaker: K. Eric Wommack
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Understanding the role of virus-host interactions in tissue tropism of plant viruses
      Understanding the role of virus-host interactions in tissue tropism...
      To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
      Speaker: Svetlana Y. Folimonova
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 09, 2020 | 12:00 AM
      How Plant Virology Informs Emergence of Zoonotic Viruses Such as SARS-COV-2
      How Plant Virology Informs Emergence of Zoonotic Viruses Such...
      The statement by Dimitri Ivanovsky in 1882 that "the sap of leaves infected with tobacco mosaic disease retains its infectious properties even after filtration through Chamberland filte...
      Speaker: Michael Goodin, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      3
      SEP 02, 2020 | 7:00 AM
      Whole transcriptome in situ cell atlas reveals cellular composition and interactions in the developing human brain
      Whole transcriptome in situ cell atlas reveals cellular composition...
      DATE: September 2, 2020 TIME: 03:00pm PDT, 6:00pm EDT Spatial omics is an expanding collection of methods to examine biological molecules in their geographical context. By retaining the prec...
      Speaker: Dr. Omer Bayraktar , Pawel Zajac, Ph.D. , Dr. Rudy Van Eijsden
      Sponsored By: Illumina, NanoString Technologies
      19 3
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      JUN 24, 2020 | 9:00 AM
      Advanced quantitative fluorescence microscopy to probe the molecular dynamics of viral entry.
      Advanced quantitative fluorescence microscopy to probe the molecular...
      DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
      Speaker: Luis Alvarez, Ph.D.
      Sponsored By: Leica Microsystems
      15 1
      JUN 17, 2020 | 1:30 PM
      Insights into the Pathogenesis of COVID-19 as Revealed by Spatial Biology
      Insights into the Pathogenesis of COVID-19 as Revealed by Spatial...
      Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
      Speaker: Joseph M. Beechem, PhD , Christopher E. Mason, PhD , Robert Schwartz, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      9
      JUN 17, 2020 | 10:30 AM
      Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19 Research
      Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19...
      COVID 19 has resulted in diverse research needs ranging from mechanism and impact of the disease, to solutions to identify, combat or treat the disease. Cellular technologies such as flow an...
      Speaker: Haley R. Pugsley, PhD , Kamala Tyagarajan, PhD
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 11, 2020 | 10:00 AM
      Correlative (Cryo-)Microscopy for Cell Biology
      Correlative (Cryo-)Microscopy for Cell Biology
      DATE: June 11, 2020 TIME: 10:00am PT, 1:00pm ET Correlative light and electron microscopy (CLEM) enables biological discoveries by merging different microscopes and imaging modalities to stu...
      Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D.
      Sponsored By: Leica Microsystems, Alveole
      35 3
      JUN 03, 2020 | 12:00 AM
      Microenvironment on Demand: A breakthrough technology for personalized cell therapy discoveries
      Microenvironment on Demand: A breakthrough technology for personalized...
      NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
      Speaker: Maithreyan Srinivasan
      Presented at: Immuno-Oncology Virtual Event Series 2020
      1
      APR 22, 2020 | 12:00 AM
      Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
      Long-range technologies resolve complex genomic regions overlooked...
      Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
      Speaker: Mark Ebbert, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 22, 2020 | 12:00 AM
      Nanotherapeutics: An insight into healthcare and future multi-dimensional clinical applications
      Nanotherapeutics: An insight into healthcare and future multi-dimensional...
      In recent years Nanotherapeutics has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. It involves design, fabrication, r...
      Speaker: Pratibha Kakadia, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 1:30 PM
      Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
      Spatially Resolved Molecular Investigation of Triple Negative...
      Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
      Speaker: Dina Finan, PhD , Stephen Williams, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 12:00 PM
      Expanding the Hi-C toolbox: New high-resolution approaches for diploid genome phasing, protein-directed chromatin architecture mapping and more
      Expanding the Hi-C toolbox: New high-resolution approaches for...
      Careful and deliberate packaging of the genome is essential to ensuring correct and timely transcriptional programs. Chromatin conformation capture (3C and Hi-C) is a powerful approach for c...
      Speaker: Iain Russell, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: Dovetail Genomics
      1
      APR 21, 2020 | 7:30 AM
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
      Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
      Speaker: Scott Soderling, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: CasTag Biosciences
      1 1
    MAR 17, 2021 | 8:00 AM
    Advanced enzymes to facilitate SARS-CoV-2 research
    Advanced enzymes to facilitate SARS-CoV-2 research
    Date: March 17, 2021 Time: 08:00am (PST) Research focused on SARS-CoV-2 has become a primary focus in genomic and molecular biology fields. With a constantly changing field with new methods...
    Speaker: Li Lavelle
    Sponsored By: Thermo Fisher Scientific
    24 1
    JAN 27, 2021 | 7:00 AM
    A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
    A novel automated and simultaneous protein/antibody high-throughput...
    DATE: January 27, 2020 TIME: 7:00am PST resin columns is limited by throughput and a complicated sample preparation process, which makes it challenging to extend to high...
    Speaker: Weilin Liu, PhD
    Sponsored By: GenScript
    8
    DEC 17, 2020 | 9:00 AM
    Advancing Cell Biology with Cryo-Correlative Microscopy
    Advancing Cell Biology with Cryo-Correlative Microscopy
    Date: December 17, 2020 Time: 9:00am (PST), 12:00pm (EST) Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging moda...
    Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D. , Joseph Kim
    Sponsored By: Leica Microsystems, Alveole
    13 2
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
    OCT 15, 2020 | 8:00 AM
    Zonal Rotor Ultracentrifugation: An Effective Tool for Nanoparticle Separations at Large Scale
    Zonal Rotor Ultracentrifugation: An Effective Tool for Nanoparticle...
    DATE: October 15, 2020 TIME: 8am PDT, 11am EDT Density gradient centrifugation is an effective method for the isolation and purification of small particles. Hollow rotors capable of hosting...
    Speaker: Dr. Alexander Wittemann , Dr. Simone Plueisch
    Sponsored By: Beckman Coulter Life Sciences
    9
     
     
  • SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: IDT
    2
    SEP 23, 2020 | 10:30 AM
    iPSC- and patient- derived intestinal organoids for gastrointestinal research
    iPSC- and patient- derived intestinal organoids for gastrointestinal...
    Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
    Speaker: Kevin Su
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    SEP 17, 2020 | 2:00 PM
    Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
    Keynote Presentation: The formation of an International Collaborative...
    Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
    Speaker: Jacqueline Fabius , Nevan Krogan, PhD
    Presented at: Coronavirus Series
    1
    SEP 17, 2020 | 9:00 AM
    Preclinical Optical Imaging of Infectious Diseases
    Preclinical Optical Imaging of Infectious Diseases
    PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
    Speaker: Kevin Francis, PhD
    Presented at: Coronavirus Series
    Sponsored By: PerkinElmer
    1
    SEP 10, 2020 | 10:00 AM
    Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
    Keynote Presentation: Squeezing out understanding from sequences:...
    Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
    Speaker: K. Eric Wommack
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 09, 2020 | 12:00 AM
    Understanding the role of virus-host interactions in tissue tropism of plant viruses
    Understanding the role of virus-host interactions in tissue tropism...
    To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
    Speaker: Svetlana Y. Folimonova
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 09, 2020 | 12:00 AM
    How Plant Virology Informs Emergence of Zoonotic Viruses Such as SARS-COV-2
    How Plant Virology Informs Emergence of Zoonotic Viruses Such...
    The statement by Dimitri Ivanovsky in 1882 that "the sap of leaves infected with tobacco mosaic disease retains its infectious properties even after filtration through Chamberland filte...
    Speaker: Michael Goodin, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
    SEP 02, 2020 | 7:00 AM
    Whole transcriptome in situ cell atlas reveals cellular composition and interactions in the developing human brain
    Whole transcriptome in situ cell atlas reveals cellular composition...
    DATE: September 2, 2020 TIME: 03:00pm PDT, 6:00pm EDT Spatial omics is an expanding collection of methods to examine biological molecules in their geographical context. By retaining the prec...
    Speaker: Dr. Omer Bayraktar , Pawel Zajac, Ph.D. , Dr. Rudy Van Eijsden
    Sponsored By: Illumina, NanoString Technologies
    19 3
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    JUN 24, 2020 | 9:00 AM
    Advanced quantitative fluorescence microscopy to probe the molecular dynamics of viral entry.
    Advanced quantitative fluorescence microscopy to probe the molecular...
    DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
    Speaker: Luis Alvarez, Ph.D.
    Sponsored By: Leica Microsystems
    15 1
     
     
  • JUN 17, 2020 | 1:30 PM
    Insights into the Pathogenesis of COVID-19 as Revealed by Spatial Biology
    Insights into the Pathogenesis of COVID-19 as Revealed by Spatial...
    Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
    Speaker: Joseph M. Beechem, PhD , Christopher E. Mason, PhD , Robert Schwartz, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    9
    JUN 17, 2020 | 10:30 AM
    Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19 Research
    Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19...
    COVID 19 has resulted in diverse research needs ranging from mechanism and impact of the disease, to solutions to identify, combat or treat the disease. Cellular technologies such as flow an...
    Speaker: Haley R. Pugsley, PhD , Kamala Tyagarajan, PhD
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    1
    JUN 11, 2020 | 10:00 AM
    Correlative (Cryo-)Microscopy for Cell Biology
    Correlative (Cryo-)Microscopy for Cell Biology
    DATE: June 11, 2020 TIME: 10:00am PT, 1:00pm ET Correlative light and electron microscopy (CLEM) enables biological discoveries by merging different microscopes and imaging modalities to stu...
    Speaker: Elizabeth Wright, Ph.D. , Jae Yang, Ph.D. , Bryan Sibert, Ph.D.
    Sponsored By: Leica Microsystems, Alveole
    35 3
    JUN 03, 2020 | 12:00 AM
    Microenvironment on Demand: A breakthrough technology for personalized cell therapy discoveries
    Microenvironment on Demand: A breakthrough technology for personalized...
    NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
    Speaker: Maithreyan Srinivasan
    Presented at: Immuno-Oncology Virtual Event Series 2020
    1
    APR 22, 2020 | 12:00 AM
    Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
    Long-range technologies resolve complex genomic regions overlooked...
    Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
    Speaker: Mark Ebbert, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • APR 22, 2020 | 12:00 AM
    Nanotherapeutics: An insight into healthcare and future multi-dimensional clinical applications
    Nanotherapeutics: An insight into healthcare and future multi-dimensional...
    In recent years Nanotherapeutics has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. It involves design, fabrication, r...
    Speaker: Pratibha Kakadia, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 1:30 PM
    Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
    Spatially Resolved Molecular Investigation of Triple Negative...
    Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
    Speaker: Dina Finan, PhD , Stephen Williams, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 12:00 PM
    Expanding the Hi-C toolbox: New high-resolution approaches for diploid genome phasing, protein-directed chromatin architecture mapping and more
    Expanding the Hi-C toolbox: New high-resolution approaches for...
    Careful and deliberate packaging of the genome is essential to ensuring correct and timely transcriptional programs. Chromatin conformation capture (3C and Hi-C) is a powerful approach for c...
    Speaker: Iain Russell, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: Dovetail Genomics
    1
    APR 21, 2020 | 7:30 AM
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
    Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
    Speaker: Scott Soderling, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: CasTag Biosciences
    1 1
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