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    Method optimization

    In medical research, method optimization evaluates ways to minimize or maximize specific parameters of a study. Optimization can involve parameters such as reducing the costs associated with a procedure, limiting the materials required to develop an assay, or obtaining maximal productivity from a technique.

    Webinars

    • MAR 27, 2020 | 11:00 AM
      Determination of Full, Partial, and Empty Capsid Ratios for Adeno-Associated Virus (AAV) Analysis
      Determination of Full, Partial, and Empty Capsid Ratios for Adeno-Associated...
      DATE: March 27, 2020 TIME: 11:00am PT, 2:00pm ET Adeno-associated virus (AAV) is one of the most commonly used delivery vehicles in gene therapy development. However, the presence of product...
      Speaker: Tingting Li, MS
      Sponsored By: SCIEX
      37 1
      MAR 25, 2020 | 12:00 AM
      Solving the Hemp Challenge: Pesticide Detection
      Solving the Hemp Challenge: Pesticide Detection
      With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
      Speaker: Avinash Dalmia, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2020
      1
      FEB 28, 2020 | 9:00 AM
      Widely Applicable Charge Variant Analysis of Therapeutic Proteins
      Widely Applicable Charge Variant Analysis of Therapeutic Proteins
      DATE: February 28, 2020 TIME: 9:00am PST Finding ways to bring therapeutic proteins to market faster is an ongoing challenge for global pharmaceutical development. Of all the analytical metho...
      Speaker: Peter Holper, B.S. Biochemistry and Cell Biology
      Sponsored By: Sciex
      6
      FEB 26, 2020 | 9:00 AM
      The use of 3D Models in Hepatic Biology
      The use of 3D Models in Hepatic Biology
      DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
      Speaker: Julia Tritapoe , David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      12 1
      FEB 25, 2020 | 9:00 AM
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 1
      FEB 14, 2020 | 10:00 AM
      "No Pressure" HPLC: The Analytical Alternative for Charged & Polar Analytes
      "No Pressure" HPLC: The Analytical Alternative for Charged & Polar...
      DATE: February 14, 2020 TIME: 10:00am PT, 1:00pm ET Separation challenges arise in the lab on a daily basis and you rely on a broad analytical toolset to help solve them. In this presentatio...
      Speaker: Vincent Remcho, PhD.
      Sponsored By: Sciex
      6
      JAN 01, 2020 | 6:00 AM
      Real-Time Monitoring of Striatal GPCR Mediated cAMP Signaling Using Genetically Encoded Fluorescent Sensors
      Real-Time Monitoring of Striatal GPCR Mediated cAMP Signaling...
      Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
      Speaker: Shana Augustin, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Improving the Precision and Targeting of Transcranial Magnetic Stimulation
      Improving the Precision and Targeting of Transcranial Magnetic...
      I describe a framework for improving the targeting and precision of transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique used for research and clinical applicat...
      Speaker: Luis Gomez, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      DEC 17, 2019 | 5:00 AM
      Alinity hq Sigma Metrics
      Alinity hq Sigma Metrics
      DATE: December 17, 2019 TIME: 5:00am PST, 2:00pm CET, UTC 1300...
      Speaker: Sten Westgard, MS
      Sponsored By: Abbott
      18 2
      DEC 10, 2019 | 7:00 AM
      Proven Answers for Protein, Vaccine and Gene Therapy Analysis
      Proven Answers for Protein, Vaccine and Gene Therapy Analysis
      DATE: December 11, 2019 TIME: 7:00am PST, 10:00am EST Rapid growth in the cell and gene therapy industry has generated an urgent need for robust analytics around characterization of both vec...
      Speaker: Mukesh Malik, PhD
      Sponsored By: SCIEX
      8 1
      NOV 19, 2019 | 8:00 AM
      Overcoming the Hurdles of Density Gradient Ultracentrifugation for Optimized Gene Therapy Purification Workflows
      Overcoming the Hurdles of Density Gradient Ultracentrifugation...
      DATE: November 19, 2019TIME: 8:00am PTCentrifugation has long served as a critical separation tool in countless research and production facilities spanning a wide range of discipline...
      Speaker: Ross VerHeul
      Sponsored By: Beckman Coulter Life Sciences
      7 1
      NOV 14, 2019 | 1:30 PM
      Strategies to Improve Laboratory Stewardship
      Strategies to Improve Laboratory Stewardship
      The Laboratory Stewardship Committee of the Cleveland Clinic is a multidisciplinary team of clinicians, pathologists, administrators, nurses and other caregivers. The team has a commitment t...
      Speaker: Gary Procop, MD, MS
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      3
      NOV 06, 2019 | 7:30 AM
      Toward a universal influenza virus vaccine
      Toward a universal influenza virus vaccine
      Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
      Speaker: Adolfo Garcia-Sastre, PhD
      Presented at: Influenza Virtual Event Series 2019
      4
      OCT 15, 2019 | 10:00 AM
      The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics on the PromethION
      The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics...
      DATE: October 15, 2019TIME: 10:00am PDTAdvances in Next-Generation Sequencing technologies as well as bioinformatic tools have advanced our ability to research and explore both human...
      Speaker: Josh Quick , Janina A. Krumbeck, PhD.
      Sponsored By: Zymo Research
      12
      OCT 03, 2019 | 12:00 PM
      Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
      Gene Editing Success: Considerations for maximizing your CRISPR...
      CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
      Speaker: Ryan Donnelly
      Presented at: CRISPR Virtual Event Series 2019
      Sponsored By: Horizon Discovery
      2
      SEP 25, 2019 | 10:00 AM
      Thinking Outside of the Box: Use of Hybrid PCR and Culture Approach for Identification of Bacterial Gastrointestinal Pathogens
      Thinking Outside of the Box: Use of Hybrid PCR and Culture Approach...
      DATE: September 25, 2019TIME: 10:00am PT, 1:00pm ET Stool culture is the traditional method for identification of bacterial gastrointestinal (GI pathogens. Many of theses patho...
      Speaker: Erin McElvania, PhD., D(ABMM)
      Presented at: BD MAX Webinar Library
      Sponsored By: BD
      6
      SEP 24, 2019 | 8:00 AM
      Interrogating 3D spheroid versus 2D monolayer cell models in drug discovery using cell health microplate assays
      Interrogating 3D spheroid versus 2D monolayer cell models in drug...
      DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
      Speaker: Dr. Adyary Fallarero, Ph.D. Adjunct Professor/Docent in Pharmaceutical Biology , Dr. Leticia Montoya, Ph.D., Chemistry and Biochemistry
      Sponsored By: Thermo Fisher Scientific
      9
      SEP 19, 2019 | 8:00 AM
      Importance and Role of Biomarkers in the Management of Pediatric Inflammatory Disease
      Importance and Role of Biomarkers in the Management of Pediatric...
      Learning Objectives: Review basic immuno-pathobiology of IBD and the phenotypes of IBD or IBDs - Crohn’s, Ulcerative Colitis and Indeterminate Colitis Briefly describe the epide...
      Speaker: Benjamin Gold, MD, FACG, FAAP
      Sponsored By: Diasorin
      4
      SEP 17, 2019 | 9:00 AM
      Spatial transcriptomics reveals insights into the melanoma tumour microenvironment
      Spatial transcriptomics reveals insights into the melanoma tumour...
      DATE: September 17, 2019TIME: 9:00am PTSpatial Transcriptomics (ST) technology reveals gene expression from up to one thousand spots across a tissue section. In this webinar, Dr. H...
      Speaker: Hanna Eriksson, M.D., PhD , Kim Thrane , Dr. Aida Soler , Dr. Stephen Hague
      Illumina , 10x Genomics
      2
      SEP 10, 2019 | 9:00 AM
      Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit for selecting antibodies with the complete panel in mind
      Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit...
      DATE: September 10, 2019TIME: 9:00am PDTAfter new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to ma...
      Speaker: Maria Gentile, MSc , Michael Kapinsky, PhD
      Sponsored By: Beckman Coulter Life Sciences
      14
      SEP 05, 2019 | 12:00 PM
      Advancing astrocyte research with novel tools for characterization, isolation, and cultivation
      Advancing astrocyte research with novel tools for characterization,...
      DATE: September 5, 2019TIME: 12:00pm PDTAstrocytes are a major cell type in the mammalian CNS. They are involved in a number of essential processes such as synapse formation and functio...
      Speaker: Melanie Jungblut, Ph.D
      Sponsored By: Miltenyi Biotec
      4
      JUN 26, 2019 | 9:00 AM
      Sample Management vs. Inventory Management: What is the difference?
      Sample Management vs. Inventory Management: What is the difference?
      DATE: June 26, 2019TIME: 9:00am PDT, 12:00pm EDT An excessive number of software solutions are available to help manage your clinical, biobank, or biorepository sample inform...
      Speaker: Kathi Shea , Markus Albertini, PhD
      Sponsored By: Brooks Life Sciences
      6 2
      JUN 12, 2019 | 9:00 AM
      Freeze Drying Solutions For Your Lab
      Freeze Drying Solutions For Your Lab
      DATE: June 12, 2019TIME: 9:00am PDTDoes your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize you...
      Speaker: Jenny Sprung , Megan Zimerman, B.A. in Biology
      Sponsored By: Labconco
      4
      JUN 05, 2019 | 5:00 PM
      Everyday culture practice - Improving reproducibility in cell culture
      Everyday culture practice - Improving reproducibility in cell...
      DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
      Speaker: Jessica Wagener, PhD
      Sponsored By: Eppendorf
      23 2
    MAR 27, 2020 | 11:00 AM
    Determination of Full, Partial, and Empty Capsid Ratios for Adeno-Associated Virus (AAV) Analysis
    Determination of Full, Partial, and Empty Capsid Ratios for Adeno-Associated...
    DATE: March 27, 2020 TIME: 11:00am PT, 2:00pm ET Adeno-associated virus (AAV) is one of the most commonly used delivery vehicles in gene therapy development. However, the presence of product...
    Speaker: Tingting Li, MS
    Sponsored By: SCIEX
    37 1
    MAR 25, 2020 | 12:00 AM
    Solving the Hemp Challenge: Pesticide Detection
    Solving the Hemp Challenge: Pesticide Detection
    With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
    Speaker: Avinash Dalmia, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2020
    1
    FEB 28, 2020 | 9:00 AM
    Widely Applicable Charge Variant Analysis of Therapeutic Proteins
    Widely Applicable Charge Variant Analysis of Therapeutic Proteins
    DATE: February 28, 2020 TIME: 9:00am PST Finding ways to bring therapeutic proteins to market faster is an ongoing challenge for global pharmaceutical development. Of all the analytical metho...
    Speaker: Peter Holper, B.S. Biochemistry and Cell Biology
    Sponsored By: Sciex
    6
    FEB 26, 2020 | 9:00 AM
    The use of 3D Models in Hepatic Biology
    The use of 3D Models in Hepatic Biology
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Speaker: Julia Tritapoe , David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
    12 1
    FEB 25, 2020 | 9:00 AM
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 1
     
     
  • FEB 14, 2020 | 10:00 AM
    "No Pressure" HPLC: The Analytical Alternative for Charged & Polar Analytes
    "No Pressure" HPLC: The Analytical Alternative for Charged & Polar...
    DATE: February 14, 2020 TIME: 10:00am PT, 1:00pm ET Separation challenges arise in the lab on a daily basis and you rely on a broad analytical toolset to help solve them. In this presentatio...
    Speaker: Vincent Remcho, PhD.
    Sponsored By: Sciex
    6
    JAN 01, 2020 | 6:00 AM
    Real-Time Monitoring of Striatal GPCR Mediated cAMP Signaling Using Genetically Encoded Fluorescent Sensors
    Real-Time Monitoring of Striatal GPCR Mediated cAMP Signaling...
    Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
    Speaker: Shana Augustin, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Improving the Precision and Targeting of Transcranial Magnetic Stimulation
    Improving the Precision and Targeting of Transcranial Magnetic...
    I describe a framework for improving the targeting and precision of transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique used for research and clinical applicat...
    Speaker: Luis Gomez, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    DEC 17, 2019 | 5:00 AM
    Alinity hq Sigma Metrics
    Alinity hq Sigma Metrics
    DATE: December 17, 2019 TIME: 5:00am PST, 2:00pm CET, UTC 1300...
    Speaker: Sten Westgard, MS
    Sponsored By: Abbott
    18 2
    DEC 10, 2019 | 7:00 AM
    Proven Answers for Protein, Vaccine and Gene Therapy Analysis
    Proven Answers for Protein, Vaccine and Gene Therapy Analysis
    DATE: December 11, 2019 TIME: 7:00am PST, 10:00am EST Rapid growth in the cell and gene therapy industry has generated an urgent need for robust analytics around characterization of both vec...
    Speaker: Mukesh Malik, PhD
    Sponsored By: SCIEX
    8 1
     
     
  • NOV 19, 2019 | 8:00 AM
    Overcoming the Hurdles of Density Gradient Ultracentrifugation for Optimized Gene Therapy Purification Workflows
    Overcoming the Hurdles of Density Gradient Ultracentrifugation...
    DATE: November 19, 2019TIME: 8:00am PTCentrifugation has long served as a critical separation tool in countless research and production facilities spanning a wide range of discipline...
    Speaker: Ross VerHeul
    Sponsored By: Beckman Coulter Life Sciences
    7 1
    NOV 14, 2019 | 1:30 PM
    Strategies to Improve Laboratory Stewardship
    Strategies to Improve Laboratory Stewardship
    The Laboratory Stewardship Committee of the Cleveland Clinic is a multidisciplinary team of clinicians, pathologists, administrators, nurses and other caregivers. The team has a commitment t...
    Speaker: Gary Procop, MD, MS
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    3
    NOV 06, 2019 | 7:30 AM
    Toward a universal influenza virus vaccine
    Toward a universal influenza virus vaccine
    Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
    Speaker: Adolfo Garcia-Sastre, PhD
    Presented at: Influenza Virtual Event Series 2019
    4
    OCT 15, 2019 | 10:00 AM
    The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics on the PromethION
    The 'Three Peak Challenge' for long-read, ultra-deep stool metagenomics...
    DATE: October 15, 2019TIME: 10:00am PDTAdvances in Next-Generation Sequencing technologies as well as bioinformatic tools have advanced our ability to research and explore both human...
    Speaker: Josh Quick , Janina A. Krumbeck, PhD.
    Sponsored By: Zymo Research
    12
    OCT 03, 2019 | 12:00 PM
    Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
    Gene Editing Success: Considerations for maximizing your CRISPR...
    CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
    Speaker: Ryan Donnelly
    Presented at: CRISPR Virtual Event Series 2019
    Sponsored By: Horizon Discovery
    2
     
     
  • SEP 25, 2019 | 10:00 AM
    Thinking Outside of the Box: Use of Hybrid PCR and Culture Approach for Identification of Bacterial Gastrointestinal Pathogens
    Thinking Outside of the Box: Use of Hybrid PCR and Culture Approach...
    DATE: September 25, 2019TIME: 10:00am PT, 1:00pm ET Stool culture is the traditional method for identification of bacterial gastrointestinal (GI pathogens. Many of theses patho...
    Speaker: Erin McElvania, PhD., D(ABMM)
    Presented at: BD MAX Webinar Library
    Sponsored By: BD
    6
    SEP 24, 2019 | 8:00 AM
    Interrogating 3D spheroid versus 2D monolayer cell models in drug discovery using cell health microplate assays
    Interrogating 3D spheroid versus 2D monolayer cell models in drug...
    DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
    Speaker: Dr. Adyary Fallarero, Ph.D. Adjunct Professor/Docent in Pharmaceutical Biology , Dr. Leticia Montoya, Ph.D., Chemistry and Biochemistry
    Sponsored By: Thermo Fisher Scientific
    9
    SEP 19, 2019 | 8:00 AM
    Importance and Role of Biomarkers in the Management of Pediatric Inflammatory Disease
    Importance and Role of Biomarkers in the Management of Pediatric...
    Learning Objectives: Review basic immuno-pathobiology of IBD and the phenotypes of IBD or IBDs - Crohn’s, Ulcerative Colitis and Indeterminate Colitis Briefly describe the epide...
    Speaker: Benjamin Gold, MD, FACG, FAAP
    Sponsored By: Diasorin
    4
    SEP 17, 2019 | 9:00 AM
    Spatial transcriptomics reveals insights into the melanoma tumour microenvironment
    Spatial transcriptomics reveals insights into the melanoma tumour...
    DATE: September 17, 2019TIME: 9:00am PTSpatial Transcriptomics (ST) technology reveals gene expression from up to one thousand spots across a tissue section. In this webinar, Dr. H...
    Speaker: Hanna Eriksson, M.D., PhD , Kim Thrane , Dr. Aida Soler , Dr. Stephen Hague
    Illumina , 10x Genomics
    2
    SEP 10, 2019 | 9:00 AM
    Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit for selecting antibodies with the complete panel in mind
    Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit...
    DATE: September 10, 2019TIME: 9:00am PDTAfter new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to ma...
    Speaker: Maria Gentile, MSc , Michael Kapinsky, PhD
    Sponsored By: Beckman Coulter Life Sciences
    14
     
     
  • SEP 05, 2019 | 12:00 PM
    Advancing astrocyte research with novel tools for characterization, isolation, and cultivation
    Advancing astrocyte research with novel tools for characterization,...
    DATE: September 5, 2019TIME: 12:00pm PDTAstrocytes are a major cell type in the mammalian CNS. They are involved in a number of essential processes such as synapse formation and functio...
    Speaker: Melanie Jungblut, Ph.D
    Sponsored By: Miltenyi Biotec
    4
    JUN 26, 2019 | 9:00 AM
    Sample Management vs. Inventory Management: What is the difference?
    Sample Management vs. Inventory Management: What is the difference?
    DATE: June 26, 2019TIME: 9:00am PDT, 12:00pm EDT An excessive number of software solutions are available to help manage your clinical, biobank, or biorepository sample inform...
    Speaker: Kathi Shea , Markus Albertini, PhD
    Sponsored By: Brooks Life Sciences
    6 2
    JUN 12, 2019 | 9:00 AM
    Freeze Drying Solutions For Your Lab
    Freeze Drying Solutions For Your Lab
    DATE: June 12, 2019TIME: 9:00am PDTDoes your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize you...
    Speaker: Jenny Sprung , Megan Zimerman, B.A. in Biology
    Sponsored By: Labconco
    4
    JUN 05, 2019 | 5:00 PM
    Everyday culture practice - Improving reproducibility in cell culture
    Everyday culture practice - Improving reproducibility in cell...
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    Speaker: Jessica Wagener, PhD
    Sponsored By: Eppendorf
    23 2
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