Nanoparticles: A nanoparticle is a microscopic particle with at least one dimension less than 100 nanometers (nm) in size. Nanoparticles are found in the natural world but are also synthesized for scientific research in a variety of areas such as drug delivery and renewable energy. In nanotechnology, a nanoparticle is defined as a small object, which acts as a whole unit with respect to its properties.
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From Discovery to Clinic: Comprehensive CRISPR Solutions for Therapeutic Development CRISPR gene editing has revolutionized the field of molecular biology, offering precise, efficient, and v...
Advanced Gene Therapy Development Solutions: A Comprehensive Platform for Next-Generation Therapeutic Innovation: The landscape of gene therapy has evolved dramatically over the past decade,...
When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether t...
Analytical ultracentrifugation is an established method during the development of therapeutic proteins and antibodies and contributes supporting information regarding the size, oligomerizati...
OCT 23, 2024 | 7:30 AM
C.E. CREDITS
This talk will provide an overview of our work in the design of self-assembled, functionalised peptide and protein nanoparticles, hydrogels and bio-interfaces for applications in healthcare....
The development of acid degradable linkers that rapidly hydrolyze at endosomal pHs is a central problem in the field of drug delivery. Acid degradable linkages are challenging to develop bec...
Analytical Ultracentrifugation (AUC) stands as a cornerstone technique in the realm of molecular and particle analysis, offering unparalleled insights into the size, shape, and interactions...
Determining the purity of LNPs loaded with nucleic acids can be challenging due to their size heterogeneity. Here, we present analytical ultracentrifugation (AUC) methods that use multiwavel...
DEC 07, 2023 | 10:00 AM
C.E. CREDITS
Lateral flow assay applications have become increasingly diverse in a post-pandemic world, and the areas of infectious disease and oncology continue to be at the forefront. In both areas, th...
AAVs and LNPs are complementary gene transfer systems with respect to immunogenicity, tissue tropism and types of nucleic acids, which can be delivered. AUC provides a wealth of orthogonal a...
This talk will provide an overview of our work in the design of self-assembled, functionalised peptide and protein nanoparticles, hydrogels and bio-interfaces for applications in healthcare....