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    Pathology

    Pathology: The study of disease. Pathology has been defined as "that branch of medicine which treats of the essential nature of disease. As a field of general inquiry and research, pathology addresses four components of disease: cause, mechanisms of development (pathogenesis), structural alterations of cells (morphologic changes), and the consequences of changes (clinical manifestations). A pathological condition is one caused by disease, rather than occurring physiologically.

    Webinars

    • FEB 19, 2014 | 10:00 AM
      Next-generation sequencing applications in advanced cancer samples: Experience with Ion AmpliSeq custom panels
      Next-generation sequencing applications in advanced cancer samples:...
      Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
      Speaker: Christopher Corless, MD, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Winter
      122
      FEB 06, 2014 | 10:00 AM
      Refinement of rodent anesthesia through the appropriate selection and use of physiological monitoring
      Refinement of rodent anesthesia through the appropriate selection...
      The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      4
      FEB 05, 2014 | 2:00 PM
      Rodent Health Surveillance:  Innovation driving changes
      Rodent Health Surveillance: Innovation driving changes
      Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
      Speaker: Charles Clifford, DVM, PhD, DACVP
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      4
      FEB 05, 2014 | 2:00 PM
      Guidelines for Inanimate Surgical Training and Competency Assessment; Improvement of Animal Welfare and Decreasing Confounding Factors
      Guidelines for Inanimate Surgical Training and Competency Assessment;...
      With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 1:00 PM
      Gross and Histopathologic Pathology of Rhesus Macaques
      Gross and Histopathologic Pathology of Rhesus Macaques
      This seminar will cover spontaneous diseases of Rhesus Macaques utilizing a systemic approach. It will consist of gross and histopathologic images of common pathologic conditions highlighting...
      Speaker: Olga Gonzalez, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 11:00 AM
      Ensuring and Assessing Training and/or Qualifications of Personnel in Animal Care and Use Programs: The AAALAC Perspective
      Ensuring and Assessing Training and/or Qualifications of Personnel...
      All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
      Speaker: John N Norton, D.V.M., PhD, Dipl, ABT, ACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 05, 2014 | 8:00 AM
      The 8th Edition of the Guide: An Environmental Impact
      The 8th Edition of the Guide: An Environmental Impact
      The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
      Speaker: John Bradfield, PhD, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      NOV 20, 2013 | 10:00 AM
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
      2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
      Speaker: Nicole Littmann
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      50
      OCT 17, 2013 | 9:00 AM
      C.E. CREDITS
      Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics
      Subtyping Circulating Tumor Cells in Breast Cancer for Personalized...
      Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
      Speaker: Lori M. Millner, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      86
      OCT 17, 2013 | 8:00 AM
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
      Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
      Speaker: William Clarke, PhD, MBA, DABCC
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      264
      OCT 17, 2013 | 7:00 AM
      C.E. CREDITS
      Monitoring for Chemotherapy Toxicity and Cardiac Troponin
      Monitoring for Chemotherapy Toxicity and Cardiac Troponin
      Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
      Speaker: Allan Jaffe, M.D.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 16, 2013 | 2:00 PM
      C.E. CREDITS
      Novel therapies for ALK mutated cancers
      Novel therapies for ALK mutated cancers
      Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
      Speaker: Roberto Chiarle, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Molecular Diagnostics in Detection, Diagnosis, and Prognosis of Cancer
      Molecular Diagnostics in Detection, Diagnosis, and Prognosis of...
      Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      129
      OCT 16, 2013 | 12:00 PM
      C.E. CREDITS
      New therapeutic strategies and new modes of drug resistance: From the bench to bedside and back again with the oncogene eIF4E
      New therapeutic strategies and new modes of drug resistance: From...
      The eukaryotic translation initiation factor eIF4E is a potent oncogene estimated to be elevated in about 30% of human cancers including cancers of the breast, prostate, lung, colon as well a...
      Speaker: Katherine LB Borden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      60
      OCT 16, 2013 | 12:00 PM
      Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based Proteomics and Digital Pathology
      Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
      Speaker: William M. Gallagher, PhD.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      98
      OCT 16, 2013 | 9:00 AM
      C.E. CREDITS
      Keynote: Breast Cancer Genomics and Genetics
      Keynote: Breast Cancer Genomics and Genetics
      It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
      Speaker: Charles M. Perou, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      132
      AUG 22, 2013 | 12:00 PM
      C.E. CREDITS
      Exome Sequencing as a Diagnostic Tool
      Exome Sequencing as a Diagnostic Tool
      It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
      Speaker: Pinar Bayrak-Toydemir, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      66
      AUG 22, 2013 | 10:00 AM
      C.E. CREDITS
      Clinical Interpretation of Sequence Variants
      Clinical Interpretation of Sequence Variants
      The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
      Speaker: Elaine Lyon, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      72
      AUG 22, 2013 | 7:00 AM
      C.E. CREDITS
      Warfarin Sensitivity Testing
      Warfarin Sensitivity Testing
      Anticoagulation therapy is frequently employed to prevent stroke in patients with atrial fibrillation, prophylaxis of venous thromboembolism and pulmonary embolism in patients with prosthetic...
      Speaker: Thomas P Moyer, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      64
      AUG 21, 2013 | 1:00 PM
      Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
      Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
      Cervical cancer screening has evolved significantly since the PAP smear was introduced in 1949. In particular, the association with human papillomavirus (HPV) infection and the mechanism of H...
      Speaker: Bruce K Patterson, MD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      59 1
      AUG 21, 2013 | 10:00 AM
      C.E. CREDITS
      Genomic Approaches to Discover Biomarkers of Drug Response in Cancer
      Genomic Approaches to Discover Biomarkers of Drug Response in...
      Massively parallel sequencing technology has proven to enable the identification of driver genetic alterations in patients' tumors that may be suppressed by targeted therapies. Through retros...
      Speaker: Michael F Berger, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      117
      AUG 21, 2013 | 8:00 AM
      Post Genome-Wide Association Studies
      Post Genome-Wide Association Studies
      In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      105
      AUG 21, 2013 | 8:00 AM
      C.E. CREDITS
      Clinical Applications in Pharmacogenetics
      Clinical Applications in Pharmacogenetics
      As a component of individualized medicine, pharmacogenetics (PGx) focuses on how genetic factors influence individual responses to specific medications. The clinical goals of pharmacogenetics...
      Speaker: Linnea Baudhuin, PhD, DABMG
      Presented at: Genetics and Genomics Virtual Event Series 2013
      71
      AUG 21, 2013 | 8:00 AM
      C.E. CREDITS
      Implementation of genome sequencing in a clinical diagnostic laboratory
      Implementation of genome sequencing in a clinical diagnostic laboratory
      With the technical costs of genome sequencing continuously dropping, it is now feasible to offer this assay in a clinical context. Empirical evidence suggests that genome and exome sequencing...
      Speaker: Matthew Lebo, PhD, FACMG
      Presented at: Genetics and Genomics Virtual Event Series 2013
      79
    FEB 19, 2014 | 10:00 AM
    Next-generation sequencing applications in advanced cancer samples: Experience with Ion AmpliSeq custom panels
    Next-generation sequencing applications in advanced cancer samples:...
    Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
    Speaker: Christopher Corless, MD, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Winter
    122
    FEB 06, 2014 | 10:00 AM
    Refinement of rodent anesthesia through the appropriate selection and use of physiological monitoring
    Refinement of rodent anesthesia through the appropriate selection...
    The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    4
    FEB 05, 2014 | 2:00 PM
    Rodent Health Surveillance:  Innovation driving changes
    Rodent Health Surveillance: Innovation driving changes
    Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
    Speaker: Charles Clifford, DVM, PhD, DACVP
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    4
    FEB 05, 2014 | 2:00 PM
    Guidelines for Inanimate Surgical Training and Competency Assessment; Improvement of Animal Welfare and Decreasing Confounding Factors
    Guidelines for Inanimate Surgical Training and Competency Assessment;...
    With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 1:00 PM
    Gross and Histopathologic Pathology of Rhesus Macaques
    Gross and Histopathologic Pathology of Rhesus Macaques
    This seminar will cover spontaneous diseases of Rhesus Macaques utilizing a systemic approach. It will consist of gross and histopathologic images of common pathologic conditions highlighting...
    Speaker: Olga Gonzalez, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
     
     
  • FEB 05, 2014 | 11:00 AM
    Ensuring and Assessing Training and/or Qualifications of Personnel in Animal Care and Use Programs: The AAALAC Perspective
    Ensuring and Assessing Training and/or Qualifications of Personnel...
    All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
    Speaker: John N Norton, D.V.M., PhD, Dipl, ABT, ACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 05, 2014 | 8:00 AM
    The 8th Edition of the Guide: An Environmental Impact
    The 8th Edition of the Guide: An Environmental Impact
    The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
    Speaker: John Bradfield, PhD, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    NOV 20, 2013 | 10:00 AM
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
    2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
    Speaker: Nicole Littmann
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    50
    OCT 17, 2013 | 9:00 AM
    C.E. CREDITS
    Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics
    Subtyping Circulating Tumor Cells in Breast Cancer for Personalized...
    Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
    Speaker: Lori M. Millner, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    86
    OCT 17, 2013 | 8:00 AM
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
    Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
    Speaker: William Clarke, PhD, MBA, DABCC
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    264
     
     
  • OCT 17, 2013 | 7:00 AM
    C.E. CREDITS
    Monitoring for Chemotherapy Toxicity and Cardiac Troponin
    Monitoring for Chemotherapy Toxicity and Cardiac Troponin
    Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
    Speaker: Allan Jaffe, M.D.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
    OCT 16, 2013 | 2:00 PM
    C.E. CREDITS
    Novel therapies for ALK mutated cancers
    Novel therapies for ALK mutated cancers
    Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
    Speaker: Roberto Chiarle, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Molecular Diagnostics in Detection, Diagnosis, and Prognosis of Cancer
    Molecular Diagnostics in Detection, Diagnosis, and Prognosis of...
    Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    129
    OCT 16, 2013 | 12:00 PM
    C.E. CREDITS
    New therapeutic strategies and new modes of drug resistance: From the bench to bedside and back again with the oncogene eIF4E
    New therapeutic strategies and new modes of drug resistance: From...
    The eukaryotic translation initiation factor eIF4E is a potent oncogene estimated to be elevated in about 30% of human cancers including cancers of the breast, prostate, lung, colon as well a...
    Speaker: Katherine LB Borden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    60
    OCT 16, 2013 | 12:00 PM
    Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based Proteomics and Digital Pathology
    Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
    Speaker: William M. Gallagher, PhD.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    98
     
     
  • OCT 16, 2013 | 9:00 AM
    C.E. CREDITS
    Keynote: Breast Cancer Genomics and Genetics
    Keynote: Breast Cancer Genomics and Genetics
    It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
    Speaker: Charles M. Perou, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    132
    AUG 22, 2013 | 12:00 PM
    C.E. CREDITS
    Exome Sequencing as a Diagnostic Tool
    Exome Sequencing as a Diagnostic Tool
    It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
    Speaker: Pinar Bayrak-Toydemir, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    66
    AUG 22, 2013 | 10:00 AM
    C.E. CREDITS
    Clinical Interpretation of Sequence Variants
    Clinical Interpretation of Sequence Variants
    The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
    Speaker: Elaine Lyon, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    72
    AUG 22, 2013 | 7:00 AM
    C.E. CREDITS
    Warfarin Sensitivity Testing
    Warfarin Sensitivity Testing
    Anticoagulation therapy is frequently employed to prevent stroke in patients with atrial fibrillation, prophylaxis of venous thromboembolism and pulmonary embolism in patients with prosthetic...
    Speaker: Thomas P Moyer, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    64
    AUG 21, 2013 | 1:00 PM
    Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
    Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
    Cervical cancer screening has evolved significantly since the PAP smear was introduced in 1949. In particular, the association with human papillomavirus (HPV) infection and the mechanism of H...
    Speaker: Bruce K Patterson, MD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    59 1
     
     
  • AUG 21, 2013 | 10:00 AM
    C.E. CREDITS
    Genomic Approaches to Discover Biomarkers of Drug Response in Cancer
    Genomic Approaches to Discover Biomarkers of Drug Response in...
    Massively parallel sequencing technology has proven to enable the identification of driver genetic alterations in patients' tumors that may be suppressed by targeted therapies. Through retros...
    Speaker: Michael F Berger, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    117
    AUG 21, 2013 | 8:00 AM
    Post Genome-Wide Association Studies
    Post Genome-Wide Association Studies
    In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    105
    AUG 21, 2013 | 8:00 AM
    C.E. CREDITS
    Clinical Applications in Pharmacogenetics
    Clinical Applications in Pharmacogenetics
    As a component of individualized medicine, pharmacogenetics (PGx) focuses on how genetic factors influence individual responses to specific medications. The clinical goals of pharmacogenetics...
    Speaker: Linnea Baudhuin, PhD, DABMG
    Presented at: Genetics and Genomics Virtual Event Series 2013
    71
    AUG 21, 2013 | 8:00 AM
    C.E. CREDITS
    Implementation of genome sequencing in a clinical diagnostic laboratory
    Implementation of genome sequencing in a clinical diagnostic laboratory
    With the technical costs of genome sequencing continuously dropping, it is now feasible to offer this assay in a clinical context. Empirical evidence suggests that genome and exome sequencing...
    Speaker: Matthew Lebo, PhD, FACMG
    Presented at: Genetics and Genomics Virtual Event Series 2013
    79
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