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Pathology
Pathology: The study of disease. Pathology has been defined as "that branch of medicine which treats of the essential nature of disease. As a field of general inquiry and research, pathology addresses four components of disease: cause, mechanisms of development (pathogenesis), structural alterations of cells (morphologic changes), and the consequences of changes (clinical manifestations). A pathological condition is one caused by disease, rather than occurring physiologically.
OCT 29, 2014 | 7:30 AM
The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
OCT 24, 2014 | 12:00 PM
  Influenza is a major clinical and public health issue. Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
AUG 21, 2014 | 9:45 AM
In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
AUG 21, 2014 | 8:45 AM
With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
AUG 20, 2014 | 10:45 AM
A recent publication in Nature Genetics1 analyzed TCGA data, and classified solid tumors into two mutually exclusive classes: C class tumors, driven by copy number alterations; and M class tu...
MAY 30, 2014 | 9:00 AM
Vaginitis and vaginosis, including Bacterial Vaginosis (BV), Vulvovaginal Candidiasis (VVC), and Trichomoniasis (TV), are extremely common conditions, consuming many healthcare resources and...
MAY 30, 2014 | 7:30 AM
The value of measuring lactate levels is expanding. Though generally considered a nonspecific biomarker, knowing lactate levels early in a patients presentation can provide valuable informat...
MAY 29, 2014 | 12:00 PM
Pharmcogenomics (PGx) is the 2nd potential clinical application of genomic medicine, preceded by genomic application for cancer. In the recently published, 2012 Institute of Medicine report o...
MAY 29, 2014 | 7:30 AM
Human papillomavirus (HPV) is the primary cause of cervical cancer and more than 100 types of HPV have been identified. Detection of HPV from cervical samples is associated with a 250 times...
MAY 29, 2014 | 7:30 AM
Case Example: University of Michigan Chemical Pathology LaboratoryEvery laboratory wants to achieve the highest quality possible and meet its commitment to deliver timely results. However...
MAY 29, 2014 | 6:00 AM
Governments, pathology providers, and clients relying on pathology reports face increasing conflict between burgeoning costs versus demands for service innovation. The health industry has bee...
