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    Research

    Research: comprises "creative and systematic work undertaken to increase the stock of knowledge, including knowledge of humans, culture and society, and the use of this stock of knowledge to devise new applications."

    Webinars

    • MAY 20, 2020 | 12:00 AM
      Single-cell Genomics Tools for better understanding and treatment of Human Disease
      Single-cell Genomics Tools for better understanding and treatment...
      The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
      Speaker: Anindita Basu, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 20, 2020 | 12:00 AM
      Zero-effort Analytical Method Validation
      Zero-effort Analytical Method Validation
      Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
      Speaker: Jürgen Voorgang
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 20, 2020 | 12:00 AM
      Validation of LIMS is a part of the data integrity
      Validation of LIMS is a part of the data integrity
      LIMS systems are used extensively in laboratories everywhere. As a tool in the lab we need to be able to trust the system to have the necessary data integrity. Just like the analytical metho...
      Speaker: Siri H. Segalstad
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Gene-editing by a "click-of-a-button"
      Gene-editing by a "click-of-a-button"
      If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
      Speaker: Steve Shih, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
      Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
      We describe a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray io...
      Speaker: Luke Ghislain, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      The Importance of Data Integrity: LIMS, Tools and Best Practices
      The Importance of Data Integrity: LIMS, Tools and Best Practices
      The amount of data that is produced each day is mind boggling. Over 2.5 quintillion bytes of data are created every single day, and this number continues to grow every single day. This year...
      Speaker: Christine Paszko, PhD, MT (ASCP)
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      3
      MAY 20, 2020 | 12:00 AM
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
      Speaker: Joseph de Rutte
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
      Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
      The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
      Speaker: Rémi Dangla
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      LAB 4.0 Fully automated LIMS including SAP integration
      LAB 4.0 Fully automated LIMS including SAP integration
      The digital lab is knocking at your door. In the age of digitalization and Industry 4.0, the laboratory is also on its way to the future. Lab 4.0 includes robotic systems, fully automated wo...
      Speaker: Guido von Dahlen
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 19, 2020 | 1:15 PM
      Immune Infiltration Influences the Survival of Pancreatic Cancer Patients
      Immune Infiltration Influences the Survival of Pancreatic Cancer...
      Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
      Speaker: Dana Mustafa, Ph.D.
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 1:15 PM
      Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢ Technology
      Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢...
      The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
      Speaker: Anushka Dikshit, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      3
      MAY 19, 2020 | 12:45 PM
      Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients Treated with Immune Checkpoint Therapy
      Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment...
      Immune checkpoint inhibitors (ICI) have shown durable and long-term benefits in a subset of head and neck squamous cell carcinoma (HNSCC) patients. To identify patient-responders from non-re...
      Speaker: Arutha Kulasinghe, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      2
      MAY 19, 2020 | 12:45 PM
      Assessing Immune Biomarkers of Response to Anthracyclines in Breast Cancer
      Assessing Immune Biomarkers of Response to Anthracyclines in Breast...
      Background: Pathologists have long recognized that the interaction between immune and tumour cells is critical in the development and progression of breast cancer. Studies have demonstrated...
      Speaker: Melanie Spears, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:45 AM
      Single-nucleus and Spatial Transcriptomics of Archival Pancreatic Ductal Adenocarcinoma after Neoadjuvant Treatment
      Single-nucleus and Spatial Transcriptomics of Archival Pancreatic...
      Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease and existing molecular subtypes do not inform clinical decisions. Previously-identified bulk transcriptomic sub...
      Speaker: William L. Hwang, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:45 AM
      Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint Blockade in Non-small-cell Lung Cancer (NSCLC) Using High-plex Digital Spatial Profiling
      Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint...
      The majority of patients with advanced NSCLC do not respond to monotherapy with PD-1 axis inhibition, and more robust predictive biomarkers are needed. In this study, we assessed tumor sampl...
      Speaker: Jon Zugazagoitia, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:15 AM
      A Multi-omic Single Cell and Spatial Atlas of Breast Cancer Reveals Stromal Suppression of Anti-Cancer Immunity
      A Multi-omic Single Cell and Spatial Atlas of Breast Cancer Reveals...
      We applied CITE-Seq to measure >150 cell surface immune markers and checkpoint proteins simultaneous to RNA-Sequencing. We resolve the tumour-immune milieu with high precision and reveal...
      Speaker: Alex Swarbrick, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      4
      MAY 19, 2020 | 8:00 AM
      Looking Beyond PCR: Isothermal Amplification
      Looking Beyond PCR: Isothermal Amplification
      DATE: May 19, 2020 TIME: 8:00am PT, 11:00am ET Limited sample material resulting in insufficient DNA input is a common hurdle for downstream analysis. This problem can be solved using a vari...
      Speaker: Agne Alminaite, PhD , Remigijus Skirgaila, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      71
      MAY 14, 2020 | 7:05 PM
      Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
      Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
      B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
      Speaker: Timothy Looney, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 14, 2020 | 7:05 PM
      Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
      Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
      B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
      Speaker: Timothy Looney, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 6:40 PM
      Genomic profiling of prostate cancer cells from urine using Oncomine Pan Cancer Cell Free Assay
      Genomic profiling of prostate cancer cells from urine using Oncomine...
      Genomic profiling of liquid biopsies is no longer an emerging area of clinical research, but quickly becoming translated as part of contemporary clinical trials for potential future use in t...
      Speaker: Jane Bayani, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      11
      MAY 14, 2020 | 6:40 PM
      Genomic profiling of prostate cancer cells from urine using Oncomine Pan Cancer Cell Free Assay
      Genomic profiling of prostate cancer cells from urine using Oncomine...
      Genomic profiling of liquid biopsies is no longer an emerging area of clinical research, but quickly becoming translated as part of contemporary clinical trials for potential future use in t...
      Speaker: Jane Bayani, PhD
      Presented at: OncomineWorld 2021: A virtual NGS education meeting
      6
      MAY 14, 2020 | 6:05 PM
      Experience with Oncomine Myeloid Research Assay
      Experience with Oncomine Myeloid Research Assay
      ...
      Speaker: Xia Li, Ph.D., DABMGG, CG(ASCP), FACMG
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 14, 2020 | 6:05 PM
      Experience with Oncomine Myeloid Research Assay
      Experience with Oncomine Myeloid Research Assay
      ...
      Speaker: Xia Li, Ph.D., DABMGG, CG(ASCP), FACMG
      Presented at: OncomineWorld 2021: A virtual NGS education meeting
      0
      MAY 14, 2020 | 5:40 PM
      First experience with the Ion Torrent Genexus Workflow
      First experience with the Ion Torrent Genexus Workflow
      Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
      Speaker: Dr. Kojo Elenitoba-Johnson
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      6
    MAY 20, 2020 | 12:00 AM
    Single-cell Genomics Tools for better understanding and treatment of Human Disease
    Single-cell Genomics Tools for better understanding and treatment...
    The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
    Speaker: Anindita Basu, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
    MAY 20, 2020 | 12:00 AM
    Zero-effort Analytical Method Validation
    Zero-effort Analytical Method Validation
    Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
    Speaker: Jürgen Voorgang
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
    MAY 20, 2020 | 12:00 AM
    Validation of LIMS is a part of the data integrity
    Validation of LIMS is a part of the data integrity
    LIMS systems are used extensively in laboratories everywhere. As a tool in the lab we need to be able to trust the system to have the necessary data integrity. Just like the analytical metho...
    Speaker: Siri H. Segalstad
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Gene-editing by a "click-of-a-button"
    Gene-editing by a "click-of-a-button"
    If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
    Speaker: Steve Shih, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
    Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
    We describe a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray io...
    Speaker: Luke Ghislain, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 20, 2020 | 12:00 AM
    The Importance of Data Integrity: LIMS, Tools and Best Practices
    The Importance of Data Integrity: LIMS, Tools and Best Practices
    The amount of data that is produced each day is mind boggling. Over 2.5 quintillion bytes of data are created every single day, and this number continues to grow every single day. This year...
    Speaker: Christine Paszko, PhD, MT (ASCP)
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    3
    MAY 20, 2020 | 12:00 AM
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
    Speaker: Joseph de Rutte
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
    Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
    The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
    Speaker: Rémi Dangla
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    LAB 4.0 Fully automated LIMS including SAP integration
    LAB 4.0 Fully automated LIMS including SAP integration
    The digital lab is knocking at your door. In the age of digitalization and Industry 4.0, the laboratory is also on its way to the future. Lab 4.0 includes robotic systems, fully automated wo...
    Speaker: Guido von Dahlen
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 19, 2020 | 1:15 PM
    Immune Infiltration Influences the Survival of Pancreatic Cancer Patients
    Immune Infiltration Influences the Survival of Pancreatic Cancer...
    Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
    Speaker: Dana Mustafa, Ph.D.
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
     
     
  • MAY 19, 2020 | 1:15 PM
    Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢ Technology
    Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢...
    The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
    Speaker: Anushka Dikshit, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    3
    MAY 19, 2020 | 12:45 PM
    Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients Treated with Immune Checkpoint Therapy
    Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment...
    Immune checkpoint inhibitors (ICI) have shown durable and long-term benefits in a subset of head and neck squamous cell carcinoma (HNSCC) patients. To identify patient-responders from non-re...
    Speaker: Arutha Kulasinghe, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    2
    MAY 19, 2020 | 12:45 PM
    Assessing Immune Biomarkers of Response to Anthracyclines in Breast Cancer
    Assessing Immune Biomarkers of Response to Anthracyclines in Breast...
    Background: Pathologists have long recognized that the interaction between immune and tumour cells is critical in the development and progression of breast cancer. Studies have demonstrated...
    Speaker: Melanie Spears, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 11:45 AM
    Single-nucleus and Spatial Transcriptomics of Archival Pancreatic Ductal Adenocarcinoma after Neoadjuvant Treatment
    Single-nucleus and Spatial Transcriptomics of Archival Pancreatic...
    Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease and existing molecular subtypes do not inform clinical decisions. Previously-identified bulk transcriptomic sub...
    Speaker: William L. Hwang, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 11:45 AM
    Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint Blockade in Non-small-cell Lung Cancer (NSCLC) Using High-plex Digital Spatial Profiling
    Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint...
    The majority of patients with advanced NSCLC do not respond to monotherapy with PD-1 axis inhibition, and more robust predictive biomarkers are needed. In this study, we assessed tumor sampl...
    Speaker: Jon Zugazagoitia, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
     
     
  • MAY 19, 2020 | 11:15 AM
    A Multi-omic Single Cell and Spatial Atlas of Breast Cancer Reveals Stromal Suppression of Anti-Cancer Immunity
    A Multi-omic Single Cell and Spatial Atlas of Breast Cancer Reveals...
    We applied CITE-Seq to measure >150 cell surface immune markers and checkpoint proteins simultaneous to RNA-Sequencing. We resolve the tumour-immune milieu with high precision and reveal...
    Speaker: Alex Swarbrick, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    4
    MAY 19, 2020 | 8:00 AM
    Looking Beyond PCR: Isothermal Amplification
    Looking Beyond PCR: Isothermal Amplification
    DATE: May 19, 2020 TIME: 8:00am PT, 11:00am ET Limited sample material resulting in insufficient DNA input is a common hurdle for downstream analysis. This problem can be solved using a vari...
    Speaker: Agne Alminaite, PhD , Remigijus Skirgaila, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    71
    MAY 14, 2020 | 7:05 PM
    Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
    Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
    B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
    Speaker: Timothy Looney, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 14, 2020 | 7:05 PM
    Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
    Haemato-Oncology Applications of BCR Immune Repertoire Sequencing
    B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
    Speaker: Timothy Looney, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
    MAY 14, 2020 | 6:40 PM
    Genomic profiling of prostate cancer cells from urine using Oncomine Pan Cancer Cell Free Assay
    Genomic profiling of prostate cancer cells from urine using Oncomine...
    Genomic profiling of liquid biopsies is no longer an emerging area of clinical research, but quickly becoming translated as part of contemporary clinical trials for potential future use in t...
    Speaker: Jane Bayani, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    11
     
     
  • MAY 14, 2020 | 6:40 PM
    Genomic profiling of prostate cancer cells from urine using Oncomine Pan Cancer Cell Free Assay
    Genomic profiling of prostate cancer cells from urine using Oncomine...
    Genomic profiling of liquid biopsies is no longer an emerging area of clinical research, but quickly becoming translated as part of contemporary clinical trials for potential future use in t...
    Speaker: Jane Bayani, PhD
    Presented at: OncomineWorld 2021: A virtual NGS education meeting
    6
    MAY 14, 2020 | 6:05 PM
    Experience with Oncomine Myeloid Research Assay
    Experience with Oncomine Myeloid Research Assay
    ...
    Speaker: Xia Li, Ph.D., DABMGG, CG(ASCP), FACMG
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 14, 2020 | 6:05 PM
    Experience with Oncomine Myeloid Research Assay
    Experience with Oncomine Myeloid Research Assay
    ...
    Speaker: Xia Li, Ph.D., DABMGG, CG(ASCP), FACMG
    Presented at: OncomineWorld 2021: A virtual NGS education meeting
    0
    MAY 14, 2020 | 5:40 PM
    First experience with the Ion Torrent Genexus Workflow
    First experience with the Ion Torrent Genexus Workflow
    Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
    Speaker: Dr. Kojo Elenitoba-Johnson
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
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