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    Research

    Research: comprises "creative and systematic work undertaken to increase the stock of knowledge, including knowledge of humans, culture and society, and the use of this stock of knowledge to devise new applications."

    Webinars

    • JUN 01, 2020 | 1:30 PM
      Symposium 4 - Expanding Species Diversity in Neuroscience Research
      Symposium 4 - Expanding Species Diversity in Neuroscience Research
      The goal is to inform the community of the BRAIN Initiative's support for the diversity of species used in neuroscience research. By leveraging advances in genetics and neuroscience tool...
      Speaker: Organizer(s): Karen David, Cynthia Moss
      Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
      1
      JUN 01, 2020 | 1:30 PM
      Symposium 3 - Advances in Neurotechnologies for Human Research
      Symposium 3 - Advances in Neurotechnologies for Human Research
      Novel neurotechnologies are generating exciting opportunities for groups in The BRAIN Initiative and the broader biomedical community to re-imagine the boundaries of recording and modulating...
      Speaker: Organizer(s): Phil Starr, Greg Worrell
      Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
      4
      JUN 01, 2020 | 11:30 AM
      Symposium 1 - How Can Dynamical Systems Neuroscience Reciprocally Advance Machine Learning?
      Symposium 1 - How Can Dynamical Systems Neuroscience Reciprocally...
      This symposium will feature presenters whose research, jointly considered, may propel machine learning (ML) beyond statistical pattern matching to dynamical multi-scale interpretations. Key...
      Speaker: Organizer(s): Grace M. Hwang
      Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
      3
      JUN 01, 2020 | 10:30 AM
      Neural Mechanisms of Navigation Behavior
      Neural Mechanisms of Navigation Behavior
      ...
      Speaker: Plenary Keynote: Rachel Wilson, PhD
      Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
      3
      MAY 28, 2020 | 10:00 AM
      In situ immune profiling of heart transplant biopsies improves diagnostic accuracy and rejection risk stratification
      In situ immune profiling of heart transplant biopsies improves...
      DATE: May 28, 2020 TIME: 10:00am PT, 1:00pm ET Cardiac allograft rejection is a serious concern in transplant medicine, conferring an increased risk of acute graft failure and adverse patient...
      Speaker: Eliot Peyster, MD, MSc
      Sponsored By: Akoya Biosciences
      11
      MAY 28, 2020 | 9:00 AM
      Detection of Chemical Agents in Bone by LC-MS
      Detection of Chemical Agents in Bone by LC-MS
      A recently proposed model for the incorporation of xenobiotics of clinical and forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relativ...
      Speaker: Timothy Garrett, PhD
      Presented at: Healthcare Heroes - Clinical Customer Appreciation Symposium
      1
      MAY 28, 2020 | 8:00 AM
      Novel Roles of Actin Cytoskeleton on Mitochondrial Dynamics and Homeostasis
      Novel Roles of Actin Cytoskeleton on Mitochondrial Dynamics and...
      DATE: May 28, 2020 TIME: 8AM PT, 11AM ET, 4PM GMT, 5PM CET...
      Speaker: Rajarshi Chakrabarti, PhD , Claudia Florindo, PhD , Meredith Price
      Sponsored By: Andor
      16
      MAY 28, 2020 | 7:00 AM
      How to quantify 200 metabolites with one LC-MS/MS method?
      How to quantify 200 metabolites with one LC-MS/MS method?
      The central carbon metabolism including glycolysis, the pentose phosphate pathway, and the TCA-cycle is essential for all biological systems. The measurements of metabolites involved in thes...
      Speaker: Kristaps Klavins, PhD
      Presented at: Healthcare Heroes - Clinical Customer Appreciation Symposium
      2
      MAY 27, 2020 | 9:00 AM
      Enrichment & analysis of rare antigen & virus-specific T cells
      Enrichment & analysis of rare antigen & virus-specific T cells
      DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
      Speaker: Marcello Stein, PhD.
      Sponsored By: Miltenyi Biotec
      20
      MAY 27, 2020 | 8:00 AM
      How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
      How multiplexed imaging reveals key insights into the tumor microenvironment...
      DATE: May 27, 2020 TIME: 8:00am PT, 11:00am ET Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understand...
      Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
      Sponsored By: Cytiva
      18
      MAY 26, 2020 | 8:00 AM
      Sensitivity, Selectivity, and Speed:  Solving Analytical Challenges in Endocrinology using LC-MS/MS for Clinical Research
      Sensitivity, Selectivity, and Speed: Solving Analytical Challenges...
      DATE: May 26, 2020 TIME: 8:00am PT, 11:00am ET, 4:00pm BST, 5:00pm CEST The use of LC-MS/MS technologies in Endocrinology for clinical research is an area of rapid growth. This is a result o...
      Speaker: Dominic Foley
      Sponsored By: Waters Corporation
      18
      MAY 21, 2020 | 8:00 AM
      Accelerating gene editing research using the power of flow cytometry
      Accelerating gene editing research using the power of flow cytometry
      DATE: May 21, 2020 TIME: 8:00am PDT, 11:00am EDT The advent of CRISPR has radically changed the face and pace of biological research and has unlocked unprecedented potential in the study of...
      Speaker: Natasha Jacobsen
      Sponsored By: Thermo Fisher Scientific
      22
      MAY 20, 2020 | 1:15 PM
      Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells & CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment...
      Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart®...
      Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
      Speaker: Jan Davidson, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 1:15 PM
      GeoMx® Protein Offerings: Fully validated antibodies to meet your spatial profiling needs
      GeoMx® Protein Offerings: Fully validated antibodies to meet your...
      With over 200 validated antibodies and the option to add custom antibodies, the GeoMx DSP protein portfolio offers options to fit a wide range of spatial profiling application needs. NanoStr...
      Speaker: Jenny Cronin, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      6
      MAY 20, 2020 | 12:45 PM
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
      Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
      Speaker: Juraj Adamik, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 9:00 AM
      Keynote Presentation: Quantitative biology with droplet microfluidics
      Keynote Presentation: Quantitative biology with droplet microfluidics
      Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I wi...
      Speaker: Adam Abate, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 11:45 AM
      Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
      Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
      Personalized medicine has beomce a paradigm in lung cancer management; ~ 25–30% of advanced lung cancer patients could benefit from a targeted therapy. Several guidelines currently end...
      Speaker: Noemi Reguart, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 11:45 AM
      Immune Infiltration Correlates of TP53 Mutational Status in Acute Myeloid Leukemia
      Immune Infiltration Correlates of TP53 Mutational Status in Acute...
      Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
      Speaker: Sergio Rutella, MD, PhD, FRCPath
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 11:15 AM
      Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant Ribociclib Plus Letrozole Versus Chemotherapy in PAM50 Luminal B Early Breast Cancer
      Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant...
      Background: CDK4/6 inhibitors increase tumor immunogenicity in preclinical models of breast cancer and several trials combining CDK4/6 inhibitors and anti-PD1/PDL1 therapies are underway. Ho...
      Speaker: Aleix Prat, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 11:15 AM
      Spatial Landscape of the Immune Microenvironment in Metastatic Prostate Cancer using GeoMxâ„¢ Digital Spatial Profiler
      Spatial Landscape of the Immune Microenvironment in Metastatic...
      Metastatic prostate cancer (mPC) is a phenotypically diverse disease with poor responses to immune based therapeutics. Development of immunotherapeutic strategies for mPC is hampered by the...
      Speaker: Peter Nelson, MD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 7:30 AM
      Keynote Presentation: Bridging Multiscale Physiological Systems via Microfluidics- from single cell to tissue-scale to organ-scale
      Keynote Presentation: Bridging Multiscale Physiological Systems...
      Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
      Speaker: Abraham Lee
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 10:00 AM
      How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing Daily Practice to the Targeted Treatment of Cytokine Storm
      How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing...
      The spread of severe acute respiratory syndrome coronavirus 2 (SARS CoV2), changed the daily life of medical oncologists. To keep safe both patients and healthy workers is the most important...
      Speaker: PLENARY: Paolo Ascierto, MD
      Presented at: Advancing Science - A Virtual Oncology Conference
      3
      MAY 20, 2020 | 12:00 AM
      Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
      Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
      Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Next-gen protein assays enabling precision medicine and data-driven biology
      Next-gen protein assays enabling precision medicine and data-driven...
      Proteins are the functional blocks of any biological entity from 50 nm sized viruses to the 100 ft long mammals (blue whale). They perform intra cellular, tissue, organ, system, or organism...
      Speaker: Kursad Araz, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
    JUN 01, 2020 | 1:30 PM
    Symposium 4 - Expanding Species Diversity in Neuroscience Research
    Symposium 4 - Expanding Species Diversity in Neuroscience Research
    The goal is to inform the community of the BRAIN Initiative's support for the diversity of species used in neuroscience research. By leveraging advances in genetics and neuroscience tool...
    Speaker: Organizer(s): Karen David, Cynthia Moss
    Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
    1
    JUN 01, 2020 | 1:30 PM
    Symposium 3 - Advances in Neurotechnologies for Human Research
    Symposium 3 - Advances in Neurotechnologies for Human Research
    Novel neurotechnologies are generating exciting opportunities for groups in The BRAIN Initiative and the broader biomedical community to re-imagine the boundaries of recording and modulating...
    Speaker: Organizer(s): Phil Starr, Greg Worrell
    Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
    4
    JUN 01, 2020 | 11:30 AM
    Symposium 1 - How Can Dynamical Systems Neuroscience Reciprocally Advance Machine Learning?
    Symposium 1 - How Can Dynamical Systems Neuroscience Reciprocally...
    This symposium will feature presenters whose research, jointly considered, may propel machine learning (ML) beyond statistical pattern matching to dynamical multi-scale interpretations. Key...
    Speaker: Organizer(s): Grace M. Hwang
    Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
    3
    JUN 01, 2020 | 10:30 AM
    Neural Mechanisms of Navigation Behavior
    Neural Mechanisms of Navigation Behavior
    ...
    Speaker: Plenary Keynote: Rachel Wilson, PhD
    Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
    3
    MAY 28, 2020 | 10:00 AM
    In situ immune profiling of heart transplant biopsies improves diagnostic accuracy and rejection risk stratification
    In situ immune profiling of heart transplant biopsies improves...
    DATE: May 28, 2020 TIME: 10:00am PT, 1:00pm ET Cardiac allograft rejection is a serious concern in transplant medicine, conferring an increased risk of acute graft failure and adverse patient...
    Speaker: Eliot Peyster, MD, MSc
    Sponsored By: Akoya Biosciences
    11
     
     
  • MAY 28, 2020 | 9:00 AM
    Detection of Chemical Agents in Bone by LC-MS
    Detection of Chemical Agents in Bone by LC-MS
    A recently proposed model for the incorporation of xenobiotics of clinical and forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relativ...
    Speaker: Timothy Garrett, PhD
    Presented at: Healthcare Heroes - Clinical Customer Appreciation Symposium
    1
    MAY 28, 2020 | 8:00 AM
    Novel Roles of Actin Cytoskeleton on Mitochondrial Dynamics and Homeostasis
    Novel Roles of Actin Cytoskeleton on Mitochondrial Dynamics and...
    DATE: May 28, 2020 TIME: 8AM PT, 11AM ET, 4PM GMT, 5PM CET...
    Speaker: Rajarshi Chakrabarti, PhD , Claudia Florindo, PhD , Meredith Price
    Sponsored By: Andor
    16
    MAY 28, 2020 | 7:00 AM
    How to quantify 200 metabolites with one LC-MS/MS method?
    How to quantify 200 metabolites with one LC-MS/MS method?
    The central carbon metabolism including glycolysis, the pentose phosphate pathway, and the TCA-cycle is essential for all biological systems. The measurements of metabolites involved in thes...
    Speaker: Kristaps Klavins, PhD
    Presented at: Healthcare Heroes - Clinical Customer Appreciation Symposium
    2
    MAY 27, 2020 | 9:00 AM
    Enrichment & analysis of rare antigen & virus-specific T cells
    Enrichment & analysis of rare antigen & virus-specific T cells
    DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
    Speaker: Marcello Stein, PhD.
    Sponsored By: Miltenyi Biotec
    20
    MAY 27, 2020 | 8:00 AM
    How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
    How multiplexed imaging reveals key insights into the tumor microenvironment...
    DATE: May 27, 2020 TIME: 8:00am PT, 11:00am ET Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understand...
    Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
    Sponsored By: Cytiva
    18
     
     
  • MAY 26, 2020 | 8:00 AM
    Sensitivity, Selectivity, and Speed:  Solving Analytical Challenges in Endocrinology using LC-MS/MS for Clinical Research
    Sensitivity, Selectivity, and Speed: Solving Analytical Challenges...
    DATE: May 26, 2020 TIME: 8:00am PT, 11:00am ET, 4:00pm BST, 5:00pm CEST The use of LC-MS/MS technologies in Endocrinology for clinical research is an area of rapid growth. This is a result o...
    Speaker: Dominic Foley
    Sponsored By: Waters Corporation
    18
    MAY 21, 2020 | 8:00 AM
    Accelerating gene editing research using the power of flow cytometry
    Accelerating gene editing research using the power of flow cytometry
    DATE: May 21, 2020 TIME: 8:00am PDT, 11:00am EDT The advent of CRISPR has radically changed the face and pace of biological research and has unlocked unprecedented potential in the study of...
    Speaker: Natasha Jacobsen
    Sponsored By: Thermo Fisher Scientific
    22
    MAY 20, 2020 | 1:15 PM
    Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells & CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment...
    Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart®...
    Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
    Speaker: Jan Davidson, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 1:15 PM
    GeoMx® Protein Offerings: Fully validated antibodies to meet your spatial profiling needs
    GeoMx® Protein Offerings: Fully validated antibodies to meet your...
    With over 200 validated antibodies and the option to add custom antibodies, the GeoMx DSP protein portfolio offers options to fit a wide range of spatial profiling application needs. NanoStr...
    Speaker: Jenny Cronin, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    6
    MAY 20, 2020 | 12:45 PM
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
    Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
    Speaker: Juraj Adamik, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
     
     
  • MAY 20, 2020 | 9:00 AM
    Keynote Presentation: Quantitative biology with droplet microfluidics
    Keynote Presentation: Quantitative biology with droplet microfluidics
    Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I wi...
    Speaker: Adam Abate, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 11:45 AM
    Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
    Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
    Personalized medicine has beomce a paradigm in lung cancer management; ~ 25–30% of advanced lung cancer patients could benefit from a targeted therapy. Several guidelines currently end...
    Speaker: Noemi Reguart, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 11:45 AM
    Immune Infiltration Correlates of TP53 Mutational Status in Acute Myeloid Leukemia
    Immune Infiltration Correlates of TP53 Mutational Status in Acute...
    Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
    Speaker: Sergio Rutella, MD, PhD, FRCPath
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 11:15 AM
    Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant Ribociclib Plus Letrozole Versus Chemotherapy in PAM50 Luminal B Early Breast Cancer
    Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant...
    Background: CDK4/6 inhibitors increase tumor immunogenicity in preclinical models of breast cancer and several trials combining CDK4/6 inhibitors and anti-PD1/PDL1 therapies are underway. Ho...
    Speaker: Aleix Prat, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 11:15 AM
    Spatial Landscape of the Immune Microenvironment in Metastatic Prostate Cancer using GeoMxâ„¢ Digital Spatial Profiler
    Spatial Landscape of the Immune Microenvironment in Metastatic...
    Metastatic prostate cancer (mPC) is a phenotypically diverse disease with poor responses to immune based therapeutics. Development of immunotherapeutic strategies for mPC is hampered by the...
    Speaker: Peter Nelson, MD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
     
     
  • MAY 20, 2020 | 7:30 AM
    Keynote Presentation: Bridging Multiscale Physiological Systems via Microfluidics- from single cell to tissue-scale to organ-scale
    Keynote Presentation: Bridging Multiscale Physiological Systems...
    Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
    Speaker: Abraham Lee
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 10:00 AM
    How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing Daily Practice to the Targeted Treatment of Cytokine Storm
    How COVID-19 has Changed an Immuno-oncologist's Life: from Optimizing...
    The spread of severe acute respiratory syndrome coronavirus 2 (SARS CoV2), changed the daily life of medical oncologists. To keep safe both patients and healthy workers is the most important...
    Speaker: PLENARY: Paolo Ascierto, MD
    Presented at: Advancing Science - A Virtual Oncology Conference
    3
    MAY 20, 2020 | 12:00 AM
    Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
    Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
    Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Next-gen protein assays enabling precision medicine and data-driven biology
    Next-gen protein assays enabling precision medicine and data-driven...
    Proteins are the functional blocks of any biological entity from 50 nm sized viruses to the 100 ft long mammals (blue whale). They perform intra cellular, tissue, organ, system, or organism...
    Speaker: Kursad Araz, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
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