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    Single-Molecule

    Single-Molecule methods provide access to details of a population's characteristics that are obscured by ensemble averaging. It is a powerful method used to examine a multitude of phenomena using advanced techniques such as total internal reflection (TIRF) and superresolution imaging.

    Trending News

    • NOV 19, 2016
      Cell & Molecular Biology
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      The Molecules You Leave Behind can be Used to Profile You
      A trace of us is left on everything we come into contact with, in the form of microbes and trace amounts of chemicals. R ...
      Written By: Carmen Leitch
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      NOV 16, 2016
      Cardiology
      Blueprints of the Mouse Heart More Detailed Than Ever
      Blueprints of the Mouse Heart More Detailed Than Ever
      How do heart cells follow their genetic programming to create a heart? What can mice hearts do to help scientists unders ...
      Written By: Kara Marker
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      NOV 15, 2016
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      Protein Demonstrates Link Between Aging and Age-Related Disease
      Protein Demonstrates Link Between Aging and Age-Related Disease
      Researchers at the University of Wisconsin - Madison have discovered a new protein that provides a critical link between ...
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      NOV 08, 2016
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      NOV 02, 2016
      Cell & Molecular Biology
      Supercomputer Reveals Protein Behavior in Realistic Cellular Setting
      Supercomputer Reveals Protein Behavior in Realistic Cellular Setting
      While interactions of biological molecules have been studied in depth. that work has not usually been done in the typica ...
      Written By: Carmen Leitch
      2
      OCT 29, 2016
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      Supercomputer Used to Learn More about p53, a Tumor Suppressor
      Supercomputer Used to Learn More about p53, a Tumor Suppressor
      "If you have a damaged cell, you don't want it to replicate," explained computational biophysicist Rommie ...
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      OCT 23, 2016
      Microbiology
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      Researchers Learn More About Persistent Bacteria
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      OCT 19, 2016
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      Simultaneous Translation & Degradation of RNA Occurs in Plants
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      OCT 07, 2016
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      A Berry for Cancer Treatment?
      A Berry for Cancer Treatment?
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      OCT 05, 2016
      Cell & Molecular Biology
      New Microscopy Technique can Track Molecules in Living Cells
      New Microscopy Technique can Track Molecules in Living Cells
      A powerful new microscopy tool has been created by researchers working at the Marine Biological Laboratory (MBL) capable ...
      Written By: Carmen Leitch
      3
      SEP 16, 2016
      Chemistry & Physics
      Studying the Balance of a Bubble By Stopping the Swirl
      Studying the Balance of a Bubble By Stopping the Swirl
      Science of Bubbles, stopping the Color Movement
      Written By: Jennifer Ellis
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      SEP 11, 2016
      Cell & Molecular Biology
      Function of Non-Coding RNA Linked to its Structure
      Function of Non-Coding RNA Linked to its Structure
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      Written By: Carmen Leitch
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      SEP 02, 2016
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      One Molecule Directs Stem Cells to Create new Bone
      One Molecule Directs Stem Cells to Create new Bone
      Pluripotent stem cells can form into any cell type in the human body through the process of normal human development. Cr ...
      Written By: Carmen Leitch
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      SEP 01, 2016
      Health & Medicine
      New TSRI Method Makes Building ‘One-Handed' Drugs Easier than Ever
      New TSRI Method Makes Building ‘One-Handed' Drugs Easier than Ever
      Authors of the new study include (left to right) Zhe Zhuang, Tao Liu, Jin-Quan Yu, Gang Chen and Yan-Qiao Chen. LA JOLLA ...
      Written By: The Scripps Research Institute (TSRI)
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      AUG 31, 2016
      Cancer
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      Salmonella School Scientists on How to Thwart Cancer
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      AUG 24, 2016
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      Platelets Use Mechanical Forces To Successfully Clot Blood
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      AUG 21, 2016
      Genetics & Genomics
      How tying DNA in tiny knots could find cancer drugs
      How tying DNA in tiny knots could find cancer drugs
      Image Credit: J E Theriot/Flickr There’s a new way to make tiny knotted and interlocked chemical structures that h ...
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      AUG 12, 2016
      Health & Medicine
      MIT Scientists Made a Portable Biopharmaceutical Factory
      MIT Scientists Made a Portable Biopharmaceutical Factory
      A lot of diseases and conditions are treated with biologics or biopharmaceuticals. Biopharmaceuticals are inherently mor ...
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      3
      AUG 11, 2016
      Cell & Molecular Biology
      Analysis of the Ribozyme Finds a High Tolerance for Mutations
      Analysis of the Ribozyme Finds a High Tolerance for Mutations
      In new research published in the journal Angewandte Chemie, scientists applied a high throughput methodology to study th ...
      Written By: Carmen Leitch
      2 2
      JUL 31, 2016
      Microbiology
      Molecular Switch that Triggers Bacterial Pathogenicity is Found
      Molecular Switch that Triggers Bacterial Pathogenicity is Found
      Scientists at the Department of Energy's Lawrence Berkeley National Laboratory have elucidated the process that acti ...
      Written By: Carmen Leitch
      3
      JUL 26, 2016
      Cell & Molecular Biology
      New Technique Enables Direct Selection of DNA for Sequencing
      New Technique Enables Direct Selection of DNA for Sequencing
      Targeted sequencing allows researchers to hone in on specific regions of DNA they are interested in, and enabling more c ...
      Written By: Carmen Leitch
      3
      JUL 22, 2016
      Genetics & Genomics
      Sporadic Bursts of Gene Activity Are Vital for Regulation
      Sporadic Bursts of Gene Activity Are Vital for Regulation
      Geneticists are constantly discovering new ways the genes are expressed, silenced, and altered in other ways. A new stud ...
      Written By: Kara Marker
      5
      JUL 20, 2016
      Neuroscience
      More Advances in the Treatment of Traumatic Brain Injury
      More Advances in the Treatment of Traumatic Brain Injury
      A week ago, I wrote this article about PDE4B inhibitors to treat traumatic brain injury (TBI). This kind of inhibitor is ...
      Written By: Cassidy Reich
      2
      JUL 17, 2016
      Microbiology
      Fungal Metabolite Reduces Antibiotic Resistance
      Fungal Metabolite Reduces Antibiotic Resistance
      Researchers can stimulate fungi to produce antimicrobial compounds, and in doing so they have detected a novel one. The ...
      Written By: Carmen Leitch
      3
    NOV 19, 2016
    Cell & Molecular Biology
    The Molecules You Leave Behind can be Used to Profile You
    The Molecules You Leave Behind can be Used to Profile You
    A trace of us is left on everything we come into contact with, in the form of microbes and trace amounts of chemicals. R ...
    Written By: Carmen Leitch
    2
    NOV 16, 2016
    Cardiology
    Blueprints of the Mouse Heart More Detailed Than Ever
    Blueprints of the Mouse Heart More Detailed Than Ever
    How do heart cells follow their genetic programming to create a heart? What can mice hearts do to help scientists unders ...
    Written By: Kara Marker
    3
    NOV 15, 2016
    Cell & Molecular Biology
    Protein Demonstrates Link Between Aging and Age-Related Disease
    Protein Demonstrates Link Between Aging and Age-Related Disease
    Researchers at the University of Wisconsin - Madison have discovered a new protein that provides a critical link between ...
    Written By: Carmen Leitch
    2 1
    NOV 08, 2016
    Neuroscience
    It's Never Too Early For a Head Injury
    It's Never Too Early For a Head Injury
    The research and science behind head injuries and professional football has been well known for years. Chronic Traumatic ...
    Written By: Brenda Kelley Kim
    3 1
    NOV 02, 2016
    Cell & Molecular Biology
    Supercomputer Reveals Protein Behavior in Realistic Cellular Setting
    Supercomputer Reveals Protein Behavior in Realistic Cellular Setting
    While interactions of biological molecules have been studied in depth. that work has not usually been done in the typica ...
    Written By: Carmen Leitch
    2
     
     
  • OCT 29, 2016
    Cell & Molecular Biology
    Supercomputer Used to Learn More about p53, a Tumor Suppressor
    Supercomputer Used to Learn More about p53, a Tumor Suppressor
    "If you have a damaged cell, you don't want it to replicate," explained computational biophysicist Rommie ...
    Written By: Carmen Leitch
    2
    OCT 23, 2016
    Microbiology
    Researchers Learn More About Persistent Bacteria
    Researchers Learn More About Persistent Bacteria
    Recurrent infections can be a serious problem for many patients. They can be longer lasting and more serious than a typi ...
    Written By: Carmen Leitch
    2 1
    OCT 19, 2016
    Cell & Molecular Biology
    Simultaneous Translation & Degradation of RNA Occurs in Plants
    Simultaneous Translation & Degradation of RNA Occurs in Plants
    Genes encode for proteins, and proper function of the human body depends on the regulation of the gene expression by the ...
    Written By: Carmen Leitch
    3 5
    OCT 07, 2016
    Videos
    A Berry for Cancer Treatment?
    A Berry for Cancer Treatment?
    Imagine if a single injection of a substance could eliminate cancer tumors, some within days. That would be something ex ...
    Written By: Brenda Kelley Kim
    2
    OCT 05, 2016
    Cell & Molecular Biology
    New Microscopy Technique can Track Molecules in Living Cells
    New Microscopy Technique can Track Molecules in Living Cells
    A powerful new microscopy tool has been created by researchers working at the Marine Biological Laboratory (MBL) capable ...
    Written By: Carmen Leitch
    3
     
     
  • SEP 16, 2016
    Chemistry & Physics
    Studying the Balance of a Bubble By Stopping the Swirl
    Studying the Balance of a Bubble By Stopping the Swirl
    Science of Bubbles, stopping the Color Movement
    Written By: Jennifer Ellis
    2
    SEP 11, 2016
    Cell & Molecular Biology
    Function of Non-Coding RNA Linked to its Structure
    Function of Non-Coding RNA Linked to its Structure
    Junk DNA refers to regions of the genome that did not at first appear to have any function or relevance. Research over t ...
    Written By: Carmen Leitch
    2
    SEP 02, 2016
    Cell & Molecular Biology
    One Molecule Directs Stem Cells to Create new Bone
    One Molecule Directs Stem Cells to Create new Bone
    Pluripotent stem cells can form into any cell type in the human body through the process of normal human development. Cr ...
    Written By: Carmen Leitch
    3
    SEP 01, 2016
    Health & Medicine
    New TSRI Method Makes Building ‘One-Handed' Drugs Easier than Ever
    New TSRI Method Makes Building ‘One-Handed' Drugs Easier than Ever
    Authors of the new study include (left to right) Zhe Zhuang, Tao Liu, Jin-Quan Yu, Gang Chen and Yan-Qiao Chen. LA JOLLA ...
    Written By: The Scripps Research Institute (TSRI)
    1
    AUG 31, 2016
    Cancer
    Salmonella School Scientists on How to Thwart Cancer
    Salmonella School Scientists on How to Thwart Cancer
    Cancer cells know when they’re being attacked. And one of their best counterattack strategies is to pump the chemo ...
    Written By: Xuan Pham
    3
     
     
  • AUG 24, 2016
    Cardiology
    Platelets Use Mechanical Forces To Successfully Clot Blood
    Platelets Use Mechanical Forces To Successfully Clot Blood
    Of all the different cell types circulating through the bloodstream, platelets are the cells we have to thank for instig ...
    Written By: Kara Marker
    4
    AUG 21, 2016
    Genetics & Genomics
    How tying DNA in tiny knots could find cancer drugs
    How tying DNA in tiny knots could find cancer drugs
    Image Credit: J E Theriot/Flickr There’s a new way to make tiny knotted and interlocked chemical structures that h ...
    Written By: Futurity (futurity.org)
    3
    AUG 12, 2016
    Health & Medicine
    MIT Scientists Made a Portable Biopharmaceutical Factory
    MIT Scientists Made a Portable Biopharmaceutical Factory
    A lot of diseases and conditions are treated with biologics or biopharmaceuticals. Biopharmaceuticals are inherently mor ...
    Written By: Cassidy Reich
    3
    AUG 11, 2016
    Cell & Molecular Biology
    Analysis of the Ribozyme Finds a High Tolerance for Mutations
    Analysis of the Ribozyme Finds a High Tolerance for Mutations
    In new research published in the journal Angewandte Chemie, scientists applied a high throughput methodology to study th ...
    Written By: Carmen Leitch
    2 2
    JUL 31, 2016
    Microbiology
    Molecular Switch that Triggers Bacterial Pathogenicity is Found
    Molecular Switch that Triggers Bacterial Pathogenicity is Found
    Scientists at the Department of Energy's Lawrence Berkeley National Laboratory have elucidated the process that acti ...
    Written By: Carmen Leitch
    3
     
     
  • JUL 26, 2016
    Cell & Molecular Biology
    New Technique Enables Direct Selection of DNA for Sequencing
    New Technique Enables Direct Selection of DNA for Sequencing
    Targeted sequencing allows researchers to hone in on specific regions of DNA they are interested in, and enabling more c ...
    Written By: Carmen Leitch
    3
    JUL 22, 2016
    Genetics & Genomics
    Sporadic Bursts of Gene Activity Are Vital for Regulation
    Sporadic Bursts of Gene Activity Are Vital for Regulation
    Geneticists are constantly discovering new ways the genes are expressed, silenced, and altered in other ways. A new stud ...
    Written By: Kara Marker
    5
    JUL 20, 2016
    Neuroscience
    More Advances in the Treatment of Traumatic Brain Injury
    More Advances in the Treatment of Traumatic Brain Injury
    A week ago, I wrote this article about PDE4B inhibitors to treat traumatic brain injury (TBI). This kind of inhibitor is ...
    Written By: Cassidy Reich
    2
    JUL 17, 2016
    Microbiology
    Fungal Metabolite Reduces Antibiotic Resistance
    Fungal Metabolite Reduces Antibiotic Resistance
    Researchers can stimulate fungi to produce antimicrobial compounds, and in doing so they have detected a novel one. The ...
    Written By: Carmen Leitch
    3
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