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    Translational Medicine

    Translational medicine builds on basic research advances - studies of biological processes using cell cultures, for example, or animal models - and uses them to develop new therapies or medical procedures. Accordingly, translational medicine is a highly interdisciplinary field, the primary goal of which is to coalesce assets of various natures within the individual pillars in order to improve the global healthcare system significantly.

    Webinars

    • MAR 19, 2014 | 10:00 AM
      MS Bioscreen: From the Bedside to the Bench and Back
      MS Bioscreen: From the Bedside to the Bench and Back
      We present a personalized medicine suite of software applications developed at UCSF for multiple sclerosis (MS): the MS Bioscreen. This new tool addresses the challenges of the dynamic manage...
      Speaker: Pierre-Antoine Gourraud, PhD, MPH
      Presented at: Neuroscience Virtual Event Series 2014
      25
      MAR 19, 2014 | 7:00 AM
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
      Speaker: Ahmad Salehi, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      15
      FEB 19, 2014 | 9:00 AM
      Next-generation RNA-Seq and Exome-Seq using Ion Proton Sequencer for translational oncology research
      Next-generation RNA-Seq and Exome-Seq using Ion Proton Sequencer...
      Genome sequencing technologies have enabled a rapid expansion into understanding cancer biology, drug development, and treatment resistance. Research in our laboratory has focused on the app...
      Speaker: Milan Radovich, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Winter
      106
      OCT 23, 2013 | 12:00 PM
      Cellular regulation of the molecular chaperone HSP90 by posttranslational modifications - impact on function and drug sensitivity
      Cellular regulation of the molecular chaperone HSP90 by posttranslational...
      Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
      Speaker: Len Neckers, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      2
      OCT 17, 2013 | 1:00 PM
      C.E. CREDITS
      Transcriptome sequencing in translational oncology research
      Transcriptome sequencing in translational oncology research
      Invading cancer cells leave the tumor to form distant metastases and are ultimately responsible for 90% of deaths in cancer. Reducing the ability of cancer cells to invade and metastasize cou...
      Speaker: Milan Radovich, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      64
      OCT 17, 2013 | 12:00 PM
      C.E. CREDITS
      Embracing the Complexity of Cancer: Seeing the Forest and the Trees
      Embracing the Complexity of Cancer: Seeing the Forest and the...
      Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      34
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
      Resistance to AR Signaling Inhibitors in Castration Resistant...
      While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
      Speaker: Elahe A Mostaghel, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 11:00 AM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      58
      OCT 16, 2013 | 7:00 AM
      C.E. CREDITS
      Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
      Prognostic, predictive, and surrogate biomarkers in men with castration...
      With the rapid rise in the number of therapeutic options for men with castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision-making, emphasizing the nee...
      Speaker: Andrew Armstrong, MD ScM FACP
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      96
      AUG 22, 2013 | 1:00 PM
      Embracing the Complexity of Cancer: Seeing the Forest and the Trees
      Embracing the Complexity of Cancer: Seeing the Forest and the...
      Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2013
      92
      AUG 22, 2013 | 9:00 AM
      C.E. CREDITS
      Return of Genome Sequencing Results to Physicians and Patients
      Return of Genome Sequencing Results to Physicians and Patients
      There has been considerable debate in the scientific and clinical communities regarding the return of results from genome sequencing to physicians and patients. Questions surrounding which he...
      Speaker: Cinnamon S Bloss, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      56
      AUG 22, 2013 | 9:00 AM
      C.E. CREDITS
      Management and Analysis of Pre-implantation Genetic Diagnosis Data
      Management and Analysis of Pre-implantation Genetic Diagnosis...
      During IVF procedures pre-implantation genetic diagnosis (PGD) allows for genetic profiling of embryos prior to replacement. Most PGD procedures during IVF are performed to select chromosomal...
      Speaker: Deanne Taylor, MS, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      34
      AUG 21, 2013 | 4:00 PM
      C.E. CREDITS
      Development of Targeted Next Generation Sequencing for Pharmacogenomics
      Development of Targeted Next Generation Sequencing for Pharmacogenomics
      The goal of personalized medicine is to customize healthcare to the individual patient. Pharmacogenomics, the analysis of how a patient's genetic makeup affects the individual's response to c...
      Speaker: Edward Ki Yun Leung, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      42
      AUG 21, 2013 | 8:00 AM
      Post Genome-Wide Association Studies
      Post Genome-Wide Association Studies
      In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      105
      MAY 30, 2013 | 9:00 AM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Clinical Diagnostics Virtual Event Series 2013
      19
      MAY 10, 2013 | 9:00 AM
      Renin: Clinical Utility of Renin Measurement in Hypertension
      Renin: Clinical Utility of Renin Measurement in Hypertension
       Measurement of renin and its activity is increasingly used in the evaluation of circulatory function. This is primarily driven by a higher than previously realized prevalence of primary hype...
      Speaker: Jonathan Williams, MD, MMSc
      Sponsored By: DiaSorin no, Diasorin
      49
      SEP 13, 2012 | 12:00 PM
      C.E. CREDITS
      Consumer Response to Direct-to-Consumer Personal Genomic Testing
      Consumer Response to Direct-to-Consumer Personal Genomic Testing
       Direct-to-Consumer (DTC) genome-wide disease risk profiling is currently available to individuals and provides information about one's genetic risk for a range of common polygenic diseases. ...
      Speaker: Cinnamon S Bloss, PhD
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      23
    MAR 19, 2014 | 10:00 AM
    MS Bioscreen: From the Bedside to the Bench and Back
    MS Bioscreen: From the Bedside to the Bench and Back
    We present a personalized medicine suite of software applications developed at UCSF for multiple sclerosis (MS): the MS Bioscreen. This new tool addresses the challenges of the dynamic manage...
    Speaker: Pierre-Antoine Gourraud, PhD, MPH
    Presented at: Neuroscience Virtual Event Series 2014
    25
    MAR 19, 2014 | 7:00 AM
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
    Speaker: Ahmad Salehi, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    15
    FEB 19, 2014 | 9:00 AM
    Next-generation RNA-Seq and Exome-Seq using Ion Proton Sequencer for translational oncology research
    Next-generation RNA-Seq and Exome-Seq using Ion Proton Sequencer...
    Genome sequencing technologies have enabled a rapid expansion into understanding cancer biology, drug development, and treatment resistance. Research in our laboratory has focused on the app...
    Speaker: Milan Radovich, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Winter
    106
    OCT 23, 2013 | 12:00 PM
    Cellular regulation of the molecular chaperone HSP90 by posttranslational modifications - impact on function and drug sensitivity
    Cellular regulation of the molecular chaperone HSP90 by posttranslational...
    Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
    Speaker: Len Neckers, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    2
    OCT 17, 2013 | 1:00 PM
    C.E. CREDITS
    Transcriptome sequencing in translational oncology research
    Transcriptome sequencing in translational oncology research
    Invading cancer cells leave the tumor to form distant metastases and are ultimately responsible for 90% of deaths in cancer. Reducing the ability of cancer cells to invade and metastasize cou...
    Speaker: Milan Radovich, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    64
     
     
  • OCT 17, 2013 | 12:00 PM
    C.E. CREDITS
    Embracing the Complexity of Cancer: Seeing the Forest and the Trees
    Embracing the Complexity of Cancer: Seeing the Forest and the...
    Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    34
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
    Resistance to AR Signaling Inhibitors in Castration Resistant...
    While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
    Speaker: Elahe A Mostaghel, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
    OCT 16, 2013 | 11:00 AM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    58
    OCT 16, 2013 | 7:00 AM
    C.E. CREDITS
    Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
    Prognostic, predictive, and surrogate biomarkers in men with castration...
    With the rapid rise in the number of therapeutic options for men with castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision-making, emphasizing the nee...
    Speaker: Andrew Armstrong, MD ScM FACP
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    96
    AUG 22, 2013 | 1:00 PM
    Embracing the Complexity of Cancer: Seeing the Forest and the Trees
    Embracing the Complexity of Cancer: Seeing the Forest and the...
    Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2013
    92
     
     
  • AUG 22, 2013 | 9:00 AM
    C.E. CREDITS
    Return of Genome Sequencing Results to Physicians and Patients
    Return of Genome Sequencing Results to Physicians and Patients
    There has been considerable debate in the scientific and clinical communities regarding the return of results from genome sequencing to physicians and patients. Questions surrounding which he...
    Speaker: Cinnamon S Bloss, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    56
    AUG 22, 2013 | 9:00 AM
    C.E. CREDITS
    Management and Analysis of Pre-implantation Genetic Diagnosis Data
    Management and Analysis of Pre-implantation Genetic Diagnosis...
    During IVF procedures pre-implantation genetic diagnosis (PGD) allows for genetic profiling of embryos prior to replacement. Most PGD procedures during IVF are performed to select chromosomal...
    Speaker: Deanne Taylor, MS, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    34
    AUG 21, 2013 | 4:00 PM
    C.E. CREDITS
    Development of Targeted Next Generation Sequencing for Pharmacogenomics
    Development of Targeted Next Generation Sequencing for Pharmacogenomics
    The goal of personalized medicine is to customize healthcare to the individual patient. Pharmacogenomics, the analysis of how a patient's genetic makeup affects the individual's response to c...
    Speaker: Edward Ki Yun Leung, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    42
    AUG 21, 2013 | 8:00 AM
    Post Genome-Wide Association Studies
    Post Genome-Wide Association Studies
    In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    105
    MAY 30, 2013 | 9:00 AM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Clinical Diagnostics Virtual Event Series 2013
    19
     
     
  • MAY 10, 2013 | 9:00 AM
    Renin: Clinical Utility of Renin Measurement in Hypertension
    Renin: Clinical Utility of Renin Measurement in Hypertension
     Measurement of renin and its activity is increasingly used in the evaluation of circulatory function. This is primarily driven by a higher than previously realized prevalence of primary hype...
    Speaker: Jonathan Williams, MD, MMSc
    Sponsored By: DiaSorin no, Diasorin
    49
    SEP 13, 2012 | 12:00 PM
    C.E. CREDITS
    Consumer Response to Direct-to-Consumer Personal Genomic Testing
    Consumer Response to Direct-to-Consumer Personal Genomic Testing
     Direct-to-Consumer (DTC) genome-wide disease risk profiling is currently available to individuals and provides information about one's genetic risk for a range of common polygenic diseases. ...
    Speaker: Cinnamon S Bloss, PhD
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    23
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