Follow a comprehensive curation of novel and significant discoveries in the fields of genetics and genomics by watching these webinars. Highlighted areas of interest in the fields of genetics and genomics include epigenetics, molecular genetics, hereditary disease, clinical genetics, population genetics, etc.
In 2014, the Undiagnosed Diseases Network (UDN), which is funded by the NIH, was established as a network of seven clinical sites, two sequencing cores, and a coordinating center. Later, a ce...
As genomics plays an ever expanding role in healthcare and research, educational programs focused on applied genomics have not kept pace with the demand for trained students. In this talk, w...
(Adapted from a DPYD verification document written by Hannah Stevens, Trainee Clinical Scientist) 5-Fluorouracil (5-FU) and capecitabine are fluoropyrimidine chemotherapies that are used to...
Since the introduction of single cell sequencing techniques to the genomics community, interest in its use has grown exponentially and the number of single cell publications has exploded. Th...
CRISPR/Cas9 technology has become very popular in the last 5 years and has profoundly changed our way to do genetically engineered animals. I will present the latest development in genome edi...
Much has been said about the promise of Next Generation Sequencing (NGS) to revolutionise diagnosis of rare diseases, and there are many examples of success in this arena. However, the majori...
Dr. Sigrid Reinsch will discuss NASA’s GeneLab Project whose goal is to develop a unique publicly accessible repository and collaborative workspace that hosts multi-omics datasets gener...
In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
Genome engineers can leverage an ever-expanding array of biological and computational tools to make targeted genetic changes. Maintaining and optimizing components ranging from reagent desig...
CRISPR-Cas9 based gene editing is a powerful tool which can induce heritable mutations at desired genomic loci without leaving transgenic trace in plants. Here we constructed a robust, multip...
Aging is accompanied by widespread epigenetic reprogramming, including the loss of heterochromatin and altered chromatin-associated processes. These changes compromise transcriptional precis...
Release of the first human genome assembly was a landmark achievement, and after nearly two decades of improvements, the current human reference genome (GRCh38) is the most accurate and compl...
In this presentation I will describe our latest work to obtain comprehensive genomes leveraging long and linked reads. The vast majority of NGS whole-genome data covers hundreds of thousands...
Short-read sequencing has found wide-spread use in metagenomics but the short read lengths and bias with regard to sequence composition have translated to limitations of the study of complex...
Human intestinal epithelial cells (hIECs) are arranged as a monolayer of cells and provide the first line of defense against invading pathogens. Upon viral infection hIECs upregulate type I...
Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
In recent years Nanotherapeutics has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. It involves design, fabrication, r...
With the completion of the human genome nearly two decades ago, consumers, patients, and physicians are wondering when genetic testing will go PRIME TIME. While the diagnostic utility of gen...
CRISPR (clustered regularly interspaced short palindromic repeats) RNA and CRISPR-associated genes (Cas) assemble into RNA-guided surveillance complex that targets foreign nucleic acids for d...
Over the last decade, the policy and regulatory trajectory of genomic and reproductive technologies has been a checkered one. Approaches around the world range from constitutional and crimina...
CRISPR-Cas9 gene editing is a powerful technique that enables genetic modification with greater speed and accuracy than previous approaches. In this webinar, Dr. Chen highlights the advantag...
Engineered cell therapy is an emerging field of science to target and treat cancer. Current strategies include utilizing immune cells such as T cells, NK cells and Macrophages or other cells...
The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
Karyomapping, a technique for preimplantation genetic diagnosis (PGD) of single gene disorders, involves using very few or single cells, and comes with challenges due to limited amounts of s...
Resolving the genetics of underlying Mendelian diseases as well as host immune responses to infectious diseases is an important prerequisite for understanding their biology and for ultimate...
Learning Objectives: 1. Learn why the complexity and repetitive structure of the human genome makes it impossible to detect all structural variants using short-read sequencing 2. Learn how h...
To interpret genome sequence from telomere to telomere, it is helpful end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution an...
In 2014, the Undiagnosed Diseases Network (UDN), which is funded by the NIH, was established as a network of seven clinical sites, two sequencing cores, and a coordinating center. Later, a ce...
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