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    Blood Brain Barrier

    Blood Brain Barrier: a highly selective semipermeable border that separates the circulating blood from the brain and extracellular fluid in the central nervous system (or CNS). Also known as the BBB, typically formed by endothelial cells of the capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane.

    Webinars

    • MAY 04, 2022 | 10:30 AM
      Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
      Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
      The coronavirus SARS-CoV-2 has led to a worldwide pandemic. Beside respiratory symptoms, infected people may develop neurologic dysfunctions such as loss of smell and taste, also seizures, a...
      Speaker: Susanne Krasemann, MD, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      4
      APR 22, 2021 | 5:00 PM
      Researchers share their Spatial Discoveries in Neurology Research
      Researchers share their Spatial Discoveries in Neurology Research
      Date: April 22, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) System transcriptomics of the schizophrenia brain - Phillip Khaitovich Schizophrenia tops the psychiatric disorder l...
      Speaker: Philipp Khaitovich , Joan Liu
      Sponsored By: NanoString Technologies, Illumina
      5
      APR 21, 2021 | 5:00 PM
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
      Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
      Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
      Sponsored By: NanoString Technologies, Illumina
      5
      APR 20, 2021 | 5:00 PM
      Researchers share their Spatial Discoveries in Cancer Research
      Researchers share their Spatial Discoveries in Cancer Research
      Date: April 20, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers on Oncology - Professor Joan Seoane Prof. Joan Seoane, Group Leader and Director of the Translational Re...
      Speaker: Noel De Miranda , Vasilis Stavrinides, MD
      Sponsored By: NanoString Technologies, Illumina
      4
      FEB 24, 2021 | 12:00 AM
      Preclinical evaluation of novel OT-analogs for the potential treatment of social behavioral deficits
      Preclinical evaluation of novel OT-analogs for the potential treatment...
      As pharmaceutical companies have reduced or eliminated neuroscience drug development due to high costs and low approval rates, the economic and healthcare burden of CNS disorders in the Unit...
      Speaker: Marsha Pierce, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      2
      JAN 01, 2020 | 6:00 AM
      Acoustically Targeted Molecular Neuromodulation
      Acoustically Targeted Molecular Neuromodulation
      The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
      Speaker: Mikhail Shapiro, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      2
      OCT 29, 2019 | 7:00 AM
      Optimizing high-content screening tools for physiologically-relevant 3D in vitro models
      Optimizing high-content screening tools for physiologically-relevant...
      DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
      Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'Connor
      Sponsored By: Molecular Devices
      8
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 05, 2019 | 12:00 PM
      Advancing astrocyte research with novel tools for characterization, isolation, and cultivation
      Advancing astrocyte research with novel tools for characterization,...
      DATE: September 5, 2019TIME: 12:00pm PDTAstrocytes are a major cell type in the mammalian CNS. They are involved in a number of essential processes such as synapse formation and functio...
      Speaker: Melanie Jungblut, Ph.D
      Sponsored By: Miltenyi Biotec
      4
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      MAR 14, 2019 | 12:00 PM
      Keynote Presentation: Infections and Inflammation as Possible Causes of Severe Mental Disorders - Paving the Way for new Treatment Targets
      Keynote Presentation: Infections and Inflammation as Possible...
      The immune system is linked to an increasing number of medical diseases, including lately also severe mental disorders. Hence, infections, autoimmunity and other immune responses could be inv...
      Speaker: Michael Benros, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      3
      NOV 13, 2018 | 9:00 AM
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
      Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
      DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
      Speaker: Sara Busatto
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
      MAR 14, 2018 | 6:00 AM
      Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery of Biologics for Alzheimer's Disease
      Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery...
      98% of small molecules and 100% of large molecules do not cross the blood-brain barrier (BBB). Biologics, including therapeutic antibodies (e.g. anti-amyloid antibodies), have been at the for...
      Speaker: Rachita Sumbria, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      NOV 12, 2015 | 9:00 AM
      Use of a CD200R Inhibitor to Overcome Central Nervous System Tumor Induced Immunosuppression
      Use of a CD200R Inhibitor to Overcome Central Nervous System Tumor...
      Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
      Speaker: Michael Olin
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      2
    MAY 04, 2022 | 10:30 AM
    Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
    Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
    The coronavirus SARS-CoV-2 has led to a worldwide pandemic. Beside respiratory symptoms, infected people may develop neurologic dysfunctions such as loss of smell and taste, also seizures, a...
    Speaker: Susanne Krasemann, MD, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    4
    APR 22, 2021 | 5:00 PM
    Researchers share their Spatial Discoveries in Neurology Research
    Researchers share their Spatial Discoveries in Neurology Research
    Date: April 22, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) System transcriptomics of the schizophrenia brain - Phillip Khaitovich Schizophrenia tops the psychiatric disorder l...
    Speaker: Philipp Khaitovich , Joan Liu
    Sponsored By: NanoString Technologies, Illumina
    5
    APR 21, 2021 | 5:00 PM
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
    Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
    Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
    Sponsored By: NanoString Technologies, Illumina
    5
    APR 20, 2021 | 5:00 PM
    Researchers share their Spatial Discoveries in Cancer Research
    Researchers share their Spatial Discoveries in Cancer Research
    Date: April 20, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers on Oncology - Professor Joan Seoane Prof. Joan Seoane, Group Leader and Director of the Translational Re...
    Speaker: Noel De Miranda , Vasilis Stavrinides, MD
    Sponsored By: NanoString Technologies, Illumina
    4
    FEB 24, 2021 | 12:00 AM
    Preclinical evaluation of novel OT-analogs for the potential treatment of social behavioral deficits
    Preclinical evaluation of novel OT-analogs for the potential treatment...
    As pharmaceutical companies have reduced or eliminated neuroscience drug development due to high costs and low approval rates, the economic and healthcare burden of CNS disorders in the Unit...
    Speaker: Marsha Pierce, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    2
     
     
  • JAN 01, 2020 | 6:00 AM
    Acoustically Targeted Molecular Neuromodulation
    Acoustically Targeted Molecular Neuromodulation
    The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
    Speaker: Mikhail Shapiro, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    2
    OCT 29, 2019 | 7:00 AM
    Optimizing high-content screening tools for physiologically-relevant 3D in vitro models
    Optimizing high-content screening tools for physiologically-relevant...
    DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
    Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'Connor
    Sponsored By: Molecular Devices
    8
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 05, 2019 | 12:00 PM
    Advancing astrocyte research with novel tools for characterization, isolation, and cultivation
    Advancing astrocyte research with novel tools for characterization,...
    DATE: September 5, 2019TIME: 12:00pm PDTAstrocytes are a major cell type in the mammalian CNS. They are involved in a number of essential processes such as synapse formation and functio...
    Speaker: Melanie Jungblut, Ph.D
    Sponsored By: Miltenyi Biotec
    4
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
     
     
  • JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    MAR 14, 2019 | 12:00 PM
    Keynote Presentation: Infections and Inflammation as Possible Causes of Severe Mental Disorders - Paving the Way for new Treatment Targets
    Keynote Presentation: Infections and Inflammation as Possible...
    The immune system is linked to an increasing number of medical diseases, including lately also severe mental disorders. Hence, infections, autoimmunity and other immune responses could be inv...
    Speaker: Michael Benros, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    3
    NOV 13, 2018 | 9:00 AM
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for Cancer
    Extracellular Vesicles as Diagnostic and Therapeutic Tools for...
    DATE:  November 13, 2018TIME:   9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
    Speaker: Sara Busatto
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
    MAR 14, 2018 | 6:00 AM
    Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery of Biologics for Alzheimer's Disease
    Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery...
    98% of small molecules and 100% of large molecules do not cross the blood-brain barrier (BBB). Biologics, including therapeutic antibodies (e.g. anti-amyloid antibodies), have been at the for...
    Speaker: Rachita Sumbria, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    NOV 12, 2015 | 9:00 AM
    Use of a CD200R Inhibitor to Overcome Central Nervous System Tumor Induced Immunosuppression
    Use of a CD200R Inhibitor to Overcome Central Nervous System Tumor...
    Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
    Speaker: Michael Olin
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    2
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